|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A preventive control strategy for static voltage stability based on an efficient power plant model of electric vehicles显示文摘With the increasing integration of wind farms and electric vehicles(EVs)in power systems,voltage stability is becoming more and more serious.Based on vehicle-to-grid(V2G),an efficient power plant model of EVs(E-EPP)was developed to estimate EV charging load with available corresponding response capacity under different charging strategies.A preventive control strategy based on E-EPP was proposed to maintain the static voltage stability margin(VSM)of power system above a predefined security level.Two control modes were used including the disconnection of EV charging load(‘V1G’mode)and the discharge of stored battery energy back to power grid(‘V2G’mode).A modified IEEE 14-bus system with high penetration of wind power and EVs was used to verify the effectiveness of preventive control strategy.Simulation results showed that the proposed strategy can not only improve the static voltage stability of power system with considerable wind generation,but also guarantee the travelling comfort for EV owners. | Mingshen WANG Yunfei MU Hongjie JIA Jianzhong WU Xiuping YAO Xiaodan YU Janaka EKANAYAKE | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，1： | 25 |
| 2 | Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells显示文摘Sjögren’s syndrome(SS)is a systemic autoimmune disease characterized by progressive inflammation and tissue damage in salivary glands and lacrimal glands.Our previous studies showed that myeloid-derived suppressor cells(MDSCs)exhibited impaired immunosuppressive function during disease progression in patients with SS and mice with experimental Sjögren’s syndrome(ESS),but it remains unclear whether restoring the function of MDSCs can effectively ameliorate the development of ESS.In this study,we found that murine olfactory ecto-mesenchymal stem cell-derived exosomes(OE-MSC-Exos)significantly enhanced the suppressive function of MDSCs by upregulating arginase expression and increasing ROS and NO levels.Moreover,treatment with OE-MSC-Exos via intravenous injection markedly attenuated disease progression and restored MDSC function in ESS mice.Mechanistically,OE-MSC-Exo-secreted IL-6 activated the Jak2/Stat3 pathway in MDSCs.In addition,the abundant S100A4 in OE-MSC-Exos acted as a key factor in mediating the endogenous production of IL-6 by MDSCs via TLR4 signaling,indicating an autocrine pathway of MDSC functional modulation by IL-6.Taken together,our results demonstrated that OE-MSC-Exos possess therapeutic potential to attenuate ESS progression by enhancing the immunosuppressive function of MDSCs,possibly constituting a new strategy for the treatment of Sjögren’s syndrome and other autoimmune diseases. | Ke Rui Yue Hong Qiugang Zhu Xiaofei Shi Fan Xiao Hailong Fu Qing Yin Yida Xing Xinfeng Wu Xiaodan Kong Huaxi Xu Jie Tian Shengjun Wang Liwei Lu | 2021 | Cellular & Molecular Immunology2021，18，2： | 12 |
| 3 | Dynamic frequency response from electric vehicles in the Great Britain power system显示文摘With the large penetration of renewable energy,fulfilling the balance between electricity demand and supply is a challenge to the modern power system.According to the UK government,the wind power penetration will reach 30%by the year 2020.The role of electric vehicles(EVs)contributing to frequency response was investigated.A dynamic frequency control strategy which considers the comfort level of vehicle owners was developed for EVs to regulate their power consumption according to the deviation of system frequency.A simulation model of a population of EVs equipped with such controlwas implemented inMatlab/Simulink platform.In this paper,a simplified Great Britain power system model is used to study the contribution of EVs to dynamic frequency control.The case study showed that using EVs as a demand response resource can greatly reduce the frequency deviations.And the rapid response from EVs can help reduce the operation cost of conventional generators. | Jian MENG Yunfei MU Jianzhong WU Hongjie JIA Qian DAI Xiaodan YU | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，2： | 8 |
| 4 | Structural basis of AMPK regulation by adenine nucleotides and glycogen显示文摘激活安培的蛋白质 kinase (AMPK ) 为糖尿病,肥胖,和癌症的治疗是一个中央细胞的精力传感器和精力动态平衡,和一个有希望的药目标的管理者。这里我们人的 α 的现在的低分辨率的水晶结构; 1 β 2 γ 1 holo-AMPK 建筑群跳了到它的 allosteric 调节的人安培和肝糖模仿 cyclodextrin,两个在 phosphorylated (4.05 Å) 并且 non-phosphorylated (4.60 Å) 状态。另外,我们解决了 2.95 Å人的 kinase 领域(KD ) 的结构跳了到邻近的 autoinhibitory 领域(帮助) 并且表现了广泛生物化学并且 mutational 研究。一起,这些研究由安培和肝糖说明 allosteric AMPK 调整的内在的机制,其绑定改变在交替的帮助(安培) 和糖类绑定模块(肝糖) 之间的 equilibria 相互作用。 | Xiaodan Li Lili Wang X Edward Zhou Jiyuan Ke Parker W de Waal Xin Gu M H Eileen Tan Dongye Wang Donghai Wu H Eric Xu Karsten Melcher | 2015 | Cell Research2015，25，1： | 8 |
| 5 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins显示文摘The Omicron BA.2 variant has become a dominant infective strain worldwide.Receptor binding studies show that the Omicron BA.2 spike trimer exhibits 11-fold and 2-fold higher potency in binding to human ACE2 than the spike trimer from the wildtype(WT)and Omicron BA.1 strains.The structure of the BA.2 spike trimer complexed with human ACE2 reveals that all three receptor-binding domains(RBDs)in the spike trimer are in open conformation,ready for ACE2 binding,thus providing a basis for the increased infectivity of the BA.2 strain.JMB2002,a therapeutic antibody that was shown to efficiently inhibit Omicron BA.1,also shows potent neutralization activities against Omicron BA.2.In addition,both BA.1 and BA.2 spike trimers are able to bind to mouse ACE2 with high potency.In contrast,the WT spike trimer binds well to cat ACE2 but not to mouse ACE2.The structures of both BA.1 and BA.2 spike trimer bound to mouse ACE2 reveal the basis for their high affinity interactions.Together,these results suggest a possible evolution pathway for Omicron BA.1 and BA.2 variants via a human-cat-mouse-human circle,which could have important implications in establishing an effective strategy for combating SARS-CoV-2 viral infections. | Youwei Xu Canrong Wu Xiaodan Cao Chunyin Gu Heng Liu Meriting Jiang Xiaoxi Wang Qingning Yuan Kai Wu Jia Liu Deyi Wang Xianqing He Xueping Wang Su-Jun Deng H.Eric Xu Wanchao Yin | 2022 | Cell Research2022，32，7： | 6 |
| 6 | High-Voltage Layered Ternary Oxide Cathode Materials:Failure Mechanisms and Modification Methods显示文摘Due to the large reversible capacity,high operating voltage and low cost,layered ternaryoxide cathode materials LiNixCoyAl-x-yO2(NCA)and LiNixCoyMn1-x-yO2(NCM)are considered asthe most potential candidate materials for lithium-ion batteries(LIBs)used in(hybrid)electricvehicles(EVs).However,next-generation long-range EVs require a high specific capacity(around 203 mAh·g^-1at 3.7V)at the cathode active material level,which is not provided withcurrent commercially layered ternary oxide cathodes.Increasing the operating voltage is aneffective method to improve the specific capacity of the cathode and the energy density of the battery,but the high operating voltage also causes a lot of problems,such as cation mix-ing and phase transformation,electrolyte decomposition,transition metal dissolution andmicrocracks.So far,researchers have carried out a lot of works to solve these issues.Surfacecoating,element doping and the design of electrolytes have been proved to be effective solu-tions.In this review,the failure mechanisms and modification methods of high-voltage lay-ered ternary oxide cathode materials are summarized,which could provide valuable infor-mation to the research of high-voltage layered ternary oxide cathode materials in basic sci-ence and industrial production. | Xiaodan Wang Ying Bai Xinran Wang Chuan Wu | 2020 | Chinese Journal of Chemistry2020，38，12： | 5 |
| 7 | Distribution, sources and burial fl ux of sedimentary organic matter in the East China Sea显示文摘Distribution of total organic carbon(TOC),total nitrogen(TN),stable isotope ratio of organic carbon and nitrogen(δ13 C andδ15 N)in 31 surface sediments were examined to quantitatively discriminate the source and burial of sedimentary organic matter(SOM)in the East China Sea(ECS).Results show that high content of TOC and TN occurred in the southern inner shelf and the northeast area due to the transport of organic matter(OM)from the Changjiang(Yangtze)River southwards by the Zhejiang Fujian Coastal Current(ZFCC)and the delivery from the old Huanghe(Yellow)River estuary by the Subei Coastal Current(SbCC),respectively.The signifi cant relationship of TOC to clay provided evidence that the fi ne-grained sediment was the primary carrier for SOM from the inner shelf to open sea.The TN varied proportionally to the TOC with the neglected intercept,suggesting that most of nitrogen measured was related to the SOM and the infl uence of the sorption of inorganic nitrogen was insignifi cant.The seaward enrichment ofδ13 C and seaward depletion of C/N andδ15 N illustrated the decrease of terrestrial OM(TOM)and the increase of marine OM(MOM).The close of average C/N ratio to the Redfi eld ratio indicated the minor role of terrestrial plant debris in the SOM.Distribution of bulk OM properties was ascribed to the terrestrial and marine input by the shelf circulation and phytoplankton with the contributions of 76.1%MOM and 23.9%TOM to SOM,respectively.The burial fl ux of OC ranged within 0.34–7.56 mg/(cm 2∙a)(averaged 2.80 mg/(cm 2∙a))and enriched along the shore and in the fi ne-grained area,manifesting the signifi cant input of the land-based sources and the eff ect of shelf mud depositional process on the fate of SOM.The sharp seaward decrease of burial fl uxes of terrestrial and marine OC gave evidences that the majority of organic carbon were settled in the inner shelf with the small fraction of them further transported eastwards. | WU Xiaodan WU Bin JIANG Mingyu CHANG Fengming NAN Qingyun YU Xinke Saren Gaowa | 2020 | Journal of Oceanology and Limnology2020，38，5： | 5 |
| 8 | Phosphofructokinase-1 Negatively Regulates Neurogenesis from Neural Stem Cells显示文摘Phosphofructokinase-1(PFK-1),a major regulatory glycolytic enzyme,has been implicated in the functions of astrocytes and neurons.Here,we report that PFK-1 negatively regulates neurogenesis from neural stem cells(NSCs)by targeting pro-neural transcriptional factors.Using in vitro assays,we found that PFK-1 knockdown enhanced,and PFK-1 overexpression inhibited the neuronal differentiation of NSCs,which was consistent with the findings from NSCs subjected to 5 h of hypoxia.Meanwhile,the neurogenesis induced by PFK-1 knockdown was attributed to the increased proliferation of neural progenitors and the commitment of NSCs to the neuronal lineage.Similarly,in vivo knockdown of PFK-1 also increased neurogenesis in the dentate gyrus of the hippocampus.Finally,we demonstrated that the neurogenesis mediated by PFK-1 was likely achieved by targeting mammalian achaete-scute homologue-1(Mash 1),neuronal differentiation factor(NeuroD),and sex-determining region Y(SRY)-related HMG box 2(Sox2).All together,our results reveal PFK-1 as an important regulator of neurogenesis. | Fengyun Zhang Xiaodan Qian Cheng Qin Yuhui Lin Haiyin Wu Lei Chang Chunxia Luo Dongya Zhu | 2016 | Neuroscience Bulletin2016，32，3： | 4 |
| 9 | Effects of Processing Parameters on Microstructure and Properties of Ultra High Strength Linepipe Steel显示文摘To examine the effect of processing parameters on microstructural evolution and to obtain the excellent combination of strength and toughness,simulation of thermo-mechanical processing was conducted using the Gleeble machine.Trial production was then conducted under the conditions obtained by Gleeble tests.Based on the results of microstructure analysis and mechanical property evaluation,the relationship between microstructural features and mechanical properties was elucidated.The result shows that the volume fraction of constituted phases can be controlled through adjusting the cooling rate and finish cooling temperature in order to get different strength levels.As cooling rate increases,the volume fraction of upper bainite increases,which leads to the increase of strength.The upper shelf energy(USE) increases with increasing volume fraction of acicular ferrite in bainite base because of the small effective acicular ferrite grain size.Ductile-brittle transition temperature(DBTT) decreases with increasing acicular ferrite volume fraction.High reduction in the rough stage has great influence on grain refinement. | Xiaodan Wu Hakcheol Lee Young Min Kim Nack J.Kim | 2012 | Journal of Materials Science & Technology2012，28，10： | 4 |
| 10 | Ultrafine monolayer Co-containing layered double hydroxide nanosheets for water oxidation显示文摘For many two-dimensional(2D)materials,low coordination edges and corner sites offer greatly enhanced catalytic performance compared to basal sites,motivating the search for new synthetic approaches towards ultrathin and ultrafine 2D nanomaterials with high specific surface areas.To date,the synthesis of catalysts that are both ultrathin(monolayer)and ultrafine(lateral size<10nm)has proven extremely challenging.Herein,using a facile ultrasonic exfoliation procedure,we describe the successful synthesis of ultrafine ZnCo-LDH nanosheets(denoted as ZnCo-UF)with a size^3.5 nm and thickness^0.5 nm.The single layer ZnCo-UF nanosheets possess an abundance of oxygen vacancies(Vo)and unsaturated coordination s让es,thereby affording outstanding electrocatalytic water oxidation performance.DFT calculations confirmed that Vo on the surface of ZnCo-UF enhanced H20 adsorption via increasing the electropositivity of the nanosheets. | Xiaodan Jia Xin Zhang Jiaqing Zhao Yufei Zhao Yunxuan Zhao Geoffrey I.N.Waterhouse Run Shi Li-Zhu Wu Chen-Ho Tung Tierui Zhang | 2019 | Journal of Energy Chemistry2019，28，7： | 3 |
| 11 | Glycomolecules in Echinococcus granulosus cyst fluid inhibit TLR4-mediated inflammatory responses via c-Raf显示文摘Cystic echinococcosis,which is caused by larval infection of Echinococcus granulosus(E.granulosus)sensu lato,is a widespread chronic cyst-forming helminthic disease that affects up to 3 million people.1 E.granulosus can actively divert the host immune response towards anergy and anti-inflammatory pathways.2 Previous studies have shown that E.granulosus can escape host immunosurveillance by modulating the maturation of dendritic cells(DCs).3,4 Nevertheless,how E.granulosus,an extracellular pathogen,modulates the inflammatory response in DCs remains poorly understood.In this study,we investigated the effects of E.granulosus cyst fluid(EgCF)on bone marrow-derived DCs(BMDCs)exposed to LPS,an inflammatory stimulus,and the mechanisms involved in the EgCF–DCs immune modulation. | Jun Hou Linlin Li Dan Dong Lianghai Wang Xian Wang Kun Yang Xiaodan Xu Congzhe Chen Xiangwei Wu Xueling Chen | 2020 | Cellular & Molecular Immunology2020，17，4： | 3 |
| 12 | A Vesicular Stomatitis Virus-Based Vaccine Carrying Zika Virus Capsid Protein Protects Mice from Viral Infection显示文摘Dear Editor,Zika virus (ZIKV) is a mosquito-borne virus that belongs to the Flavivirus family along with dengue virus (DENV),yellow fever virus, West Nile virus, and Japanese encephalitis virus (Ming et al. 2016). ZIKV is a singlestranded positive-sense RNA virus encoding three structural proteins, including nucleocapsid protein C, prM/M,envelope glycoprotein E, and seven non-structural proteins.Since 2015. | Xiaodan Shi Jingping Hu Jing Guo Chuanjian Wu Sidong Xiong Chunsheng Dong | 2019 | Virologica Sinica2019，34，1： | 2 |
| 13 | Exposure measurement, risk assessment and source identification for exposure of traffic assistants to particle-bound PAHs in Tianjin, China显示文摘To investigate the levels of exposure to particulate-bound polycyclic aromatic hydrocarbon(PAH) and to estimate the risk these levels pose to traffic assistants(TAs) in Tianjin(a megacity in North China), a measurement campaign(33 all-day exposure samples, 25 occupational-exposure samples and 10 indoor samples) was conducted to characterize the TAs' exposure to PAHs, assess the cancer risk and identify the potential sources of exposure. The average total exposure concentration of 14 PAHs was approximately 2871 ± 928 ng/m3(on-duty), and 1622 ± 457 ng/m3(all-day). The indoor PAHs level was 1257 ± 107 ng/m3. After 8000 Monte Carlo simulations, the cancer risk resulting from exposure to PAHs was found to be approximately 1.05 × 10-4. A multivariate analysis was applied to identify the potential sources, and the results showed that, in addition to vehicle exhaust, coal combustion and cooking fumes were also another two important contributors to personal PAH exposure. The diagnostic ratios of PAH compounds agree with the source apportionment results derived from principal component analysis. | Xiaodan Xue Yan You Jianhui Wu Bin Han Zhipeng Bai Naijun Tang Liwen Zhang | 2014 | Journal of Environmental Sciences2014，26，2： | 2 |
| 14 | Zn/Sr dual ions-collagen co-assembly hydroxyapatite enhances bone regeneration through procedural osteo-immunomodulation and osteogenesis显示文摘The immune microenvironment induced by biomaterials played vital roles in bone regeneration.Hydroxyapatite(HA)and its ion-substituted derivates represent a large class of core inorganic materials for bone tissue engineering.Although ion substitution was proved to be a potent way to grant HA more biological functions,few studies focused on the immunomodulatory properties of ion-doped HA.Herein,to explore the potential osteoimmunomodulatory effects of ion-doped HA,zinc and strontium co-assembled into HA through a collagen template biomimetic way(ZnSr-Col-HA)was successfully achieved.It was found that ZnSr-Col-HA could induce a favorable osteo-immune microenvironment by stimulating macrophages.Furthermore,ZnSr-Col-HA demonstrated a procedural promoting effect on osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs)in vitro.Specifically,the osteo-immune microenvironment acted as a dominant factor in promoting osteogenic gene expressions at the early stage through OSM signal pathway.Whereas the direct stimulating effects on BMSCs by Zn^(2+)/Sr^(2+) were more effectively at the later stage with Nfatc1/Maf and Wnt signals activated.In vivo study confirmed strong promoting effects of ZnSr-Col-HA on critical-sized cranial defect repair.The current study indicated that such a combined biomaterial design philosophy of dual ion-doping and biomimetic molecular co-assembly to endow HA applicable osteoimmunomodulatory characteristics might bring up a new cutting-edge concept for bone regeneration study. | Zhenyu Zhong Xiaodan Wu Yifan Wang Mengdie Li Yan Li XuLong Liu Xin Zhang Ziyang Lan Jianglin Wang Yingying Du Shengmin Zhang | 2022 | Bioactive Materials2022，7，4： | 2 |
| 15 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 16 | Polymer Micelle with pH-Triggered Hydrophobic-Hydrophilic Transition and De-Cross-Linking Process in the Core and Its Application for Targeted Anticancer Drug Delivery显示文摘 | Jianquan Fan Fang Zeng Shuizhu Wu Xiaodan Wang | 2012 | Biomacromolecules2012，13，： | 1 |
| 17 | Can lung cancer stem cells be targeted for therapies?显示文摘 | Xiaodan Wu Hong Chen Xiangdong Wang | 2012 | Cancer Treatment Reviews2012，，6： | 1 |
| 18 | Recent progress in perovskite solar cells:from device to commercialization显示文摘Perovskite solar cells(PSCs) are undergoing rapid development and the power conversion efficiency reaches 25.7% which attracts increasing attention on their commercialization recently.In this review,we summarized the recent progress of PSCs based on device structures,perovskite-based tandem cells,large-area modules,stability,applications and industrialization.Last,the challenges and perspectives are discussed,aiming at providing a thrust for the commercialization of PSCs in the near future. | Xinhui Luo Xuesong Lin Feng Gao Yang Zhao Xiaodong Li Liqing Zhan Zexiong Qiu Jin Wang Cong Chen Lei Meng Xiaofeng Gao Yu Zhang Zijian Huang Rundong Fan Huifen Liu Yanrun Chen Xiaoxue Ren Jiahong Tang Chun-Hao Chen Dong Yang Yongguang Tu Xiao Liu Dongxue Liu Qing Zhao Jingbi You Junfeng Fang Yongzhen Wu Hongwei Han Xiaodan Zhang Dewei Zhao Fuzhi Huang Huanping Zhou Yongbo Yuan Qi Chen Zhaokui Wang Shengzhong(Frank)Liu Rui Zhu Jotaro Nakazaki Yongfang Li Liyuan Han | 2022 | Science China Chemistry2022，65，12： | 1 |
| 19 | Enhanced photocatalytic activity of (Zn, N)-codoped TiO 2 nanoparticles显示文摘 | Huarong Zhang Yong Liang Xiaodan Wu Haiwu Zheng | 2012 | Materials Research Bulletin2012，，9： | 1 |
| 20 | A new SO2,SO3 Sensor with Ag2SO4-Based Electrolyte显示文摘 | Liu Qingguo Xiaodan Wu Weijiang | 1990 | Solid State Ionics1990，4041，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员