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8篇 您的检索式:作者名="Manolis Pasparakis"
    题名 作者 年代 出处 被引量
1Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury显示文摘Yumiko Imai Keiji Kuba G. Greg Neely Rubina Yaghubian-Malhami Thomas Perkmann Geert van Loo Maria Ermolaeva Ruud Veldhuizen Y.H. Connie Leung Hongliang Wang Haolin Liu Yang Sun Manolis Pasparakis Manfred Kopf Christin Mech Sina Bavari J.S. Malik Peiris Ar 2008Cell2008,,2:4
2Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis显示文摘Ralph Gareus Elena Kotsaki Sofia Xanthoulea Ingeborg van der Made Marion J.J. Gijbels Rozina Kardakaris Apostolos Polykratis George Kollias Menno P.J. de Winther Manolis Pasparakis 2008Cell Metabolism2008,,5:2
3Inducing Z-DNA overcomes immune checkpoint blockade resistance显示文摘Inducing immunogenic cell death in tumors holds promise in stimulating anti-tumor immunity.A recent study published in Nature reported that a small molecule previously shown to induce the formation of Z-DNA activates ZBP1-dependent cell death and renders tumors sensitive to immune checkpoint blockade-based immunotherapy.Cancer immunotherapy by immune checkpoint blockade(ICB)has achieved remarkable success in individual cases;however,these are still restricted to a small number of patients.Therefore,novel approaches to enhance anti-tumor immunity are urgently needed.Induction of immunogenic cell death,such as necroptosis,in tumor cells was shown to synergize with ICB to induce antitumor immune responses in mouse models.1 The RNA-editing enzyme adenosine deaminase acting on RNA 1(ADAR1)has emerged as a novel checkpoint conferring resistance to ICB therapy.Huipeng Jiao Manolis Pasparakis 2022Cell Research2022,32,10:1
4Inhi bition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice显示文摘Edwin Kanters Manolis Pasparakis Marion J Gijbels 2003Clin Invest2003,112,:1
5Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma显示文摘Tom Luedde Naiara Beraza Vasileios Kotsikoris Geert van Loo Arianna Nenci Rita De Vos Tania Roskams Christian Trautwein Manolis Pasparakis 2007Cancer Cell2007,,2:1
6Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements显示文摘Dimitris Kontoyiannis Manolis Pasparakis Theresa T Pizarro Fabio Cominelli George Kollias 1999Immunity1999,,3:1
7Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases显示文摘Sofia Xanthoulea Manolis Pasparakis Stavroula Kousteni 2004J Exp Med2004,200,3:1
8IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages显示文摘David G. Saliba Andreas Heger Hayley L. Eames Spyros Oikonomopoulos Ana Teixeira Katrina Blazek Ariadne Androulidaki Daniel Wong Fui G. Goh Miriam Weiss Adam Byrne Manolis Pasparakis Jiannis Ragoussis Irina A. Udalova 2014Cell Reports2014,,5:1
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