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| 1 | A Survey on Expert Recommendation in Community Question Answering显示文摘 | Xianzhi Wang Chaoran Huang Lina Yao Boualem Benatallah Manqing Dong | 2018 | Journal of Computer Science & Technology2018，33，4： | 10 |
| 2 | Modelling of tropospheric delays in geosynchronous synthetic aperture radar显示文摘As a direct consequence of the orbital height, the integration time in geosynchronous synthetic aperture radar(GEO SAR) with metric or decimetric azimuth resolutions is in the order of several hundreds or even thousands of seconds. With such long integration time, the compensation of residual tropospheric propagation terms poses one of the fundamental challenges associated with GEO SAR missions. In order to better characterise the impact of the propagation errors on GEO SAR imaging, we put forward a model for the simulation of the tropospheric delay appropriate for the accurate simulation of GEO SAR surveys. The suggested model, with a deterministic background component and a random turbulent one, incorporates some of the most recent meteorological data for the characterization of the troposphere. To illustrate the relevance of the derivation, the suggested model is used for performance estimation and raw data simulation of GEO SAR raw data. Substantial conclusion on the system impulse response and the associated calibration requirements is also drawn from the analysis. | Dexin LI Marc RODRIGUEZ-CASSOLA Pau PRATS-IRAOLA Zhen DONG Manqing WU Alberto MOREIRA | 2017 | Science China(Information Sciences)2017，60，6： | 4 |
| 3 | The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases显示文摘Alzheimer's disease(AD)is a neurodegenerative disease characterized by progressive cognitive decline,accompanied by amyloid-β(Aβ)overload and hyperphosphorylated tau accumulation in the brain.Synaptic dysfunction,an important pathological hallmark in AD;is recognized as the main cause of the cognitive impairments.Accumulating evidence suggests that synaptic dysfunction could be an early pathological event in AD.Pathological tau,which is detached from axonal microtubules and mislocalized into pre-and postsynaptic neuronal compartments,is suggested to induce synaptic dysfunction in several ways,including reducing mobility and release of presynaptic vesicles,decreasing glutamatergic receptors,impairing the maturation of dendritic spines at postsynaptic terminals,disrupting mitochondrial transport and function in synapses,and promoting the phagocytosis of synapses by microglia.Here,we review the current understanding of how pathological tau mediates synaptic dysfunction and contributes to cognitive decline in AD.We propose that elucidating the mechanism by which pathological tau impairs synaptic function is essential for exploring novel therapeutic strategies for AD. | Moxin Wu Manqing Zhang Xiaoping Yin Kai Chen Zhijian Hu Qin Zhou Xianming Cao Zhiying Chen Dan Liu | 2021 | Translational Neurodegeneration2021，10，4： | 4 |
| 4 | Low-cost hybrid integrated 4 × 25 GBaud PAM-4CWDM ROSA with a PLC-based arrayed waveguide grating de-multiplexer显示文摘We demonstrate a low-cost hybrid integrated and compact 100 GBaud four-lane coarse wavelength division multiplexing (CWDM) receiver optical sub-assembly (ROSA) based on an arrayed waveguide grating de-multiplexer in the O band. To achieve the horizontal light coupling between the planar light-wave circuit (PLC) based arrayed waveguide grating de-multiplexer and photodetector array, a 42°polished facet is applied for total reflection.A flexible printed circuit with high-frequency coplanar waveguides is used for a power supply of trans-impedance amplifier and signal transmission.The fabricated CWDM ROSA module, whose size is 18mm×22mm×6mm, shows a 3 dB bandwidth of 21.2,18.4,19.6,and 19.3 GHz,respectively,in each lane. The overall symbol error rates are at a magnitude of 10^-7 for 25 GBaud four-level pulse amplitude modulation (PAM-4) transmission with an average input optical power of 5dBm. | Lei Liu Limin Chang Yingxin Kuang Zezheng Li Yang Liu Huan Guan Manqing Tan Yude Yu Zhiyong Li | 2019 | Photonics Research2019，7，7： | 3 |
| 5 | A novel mutation in 5'-UTR of Makorin ring finger 3 gene associated with the familial precocious puberty显示文摘Central precocious puberty (CPP)is one of the most common and complex problems in clinical pediatric endocrinology practice. Currently,CPP is believed to result from complex interactions between genetic,endocrinal,nutritional,and environmental factors. Most CPP cases are commonly associated with an early activation of hypothalamic-pituitary-gonadal (HPG)axis followed by overproduction and release of GnRH from hypothalamus. | Wenli Lu Junqi Wang Chuanyin Li Manqing Sun Ronggui Hu Wei Wang | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 1 |
| 6 | Study of risk factors for intraoperative hypothermia during pediatric burn surgery显示文摘Background Intraoperative hypothermia(core temperature<36.0°C)is common during the perioperative period and can result in adverse consequences,especially in children.We aimed to determine the incidence of intraoperative hypothermia and its risk factors in pediatric patients during burn surgery.Methods In the present study we enrolled 197 pediatric patients with burn injury undergoing surgical debridement and skin grafting.Factors,such as total burn surface area(TBSA),were collected and analyzed to identify the potential risk factors for intraoperative hypothermia.Results The incidence of intraoperative hypothermia among all patients was 17.8%.Compared with patients with normothermia,children with hypothermia were associated with larger TBSA(25%vs 15%,p<0.001)and with less intraoperative active warming(34.28%vs 54.93%,p<0.05).In addition,compared with patients with moderate-degree burn,patients with severe and extremely severe burn were associated with much higher risk of intraoperative hypothermia[severe:odds ratio(OR)=3.805,95%confidence interval(CI)=1.396-10.368,p=0.009;extremely severe:OR=6.933,95%CI=2.604-18.462,p<0.001].TBSA was the only independent risk factor that emerged as being strongly associated with intraoperative hypothermia(OR=1.068,p=0.001)and could be used to predict the occurrence of hypothermia when combined with other factors.TBSA for predicting intraoperative hypothermia by receiver operating characteristic(ROC)curve analysis showed a good predictive ability with an area under the ROC curve of 0.758.Conclusion TBSA is an important risk factor for intraoperative hypothermia in pediatric patients with burn. | Yaoqin Hu Yangfan Tian Manqing Zhang Jialian Zhao Qiang Shu | 2021 | World Journal of Pediatric Surgery2021，4，1： | 1 |
| 7 | Effects of different C contents on the microstructure, tensile properties and stress-rupture properties of IN792 alloy显示文摘 | Jinxia Yang Qi Zheng Manqing Ji Xiaofeng Sun Zhuangqi Hu | 2010 | Materials Science & Engineering A2010，，3： | 1 |
| 8 | Off-grid correction for improving scatterer localization performance in compressive sampling SAR tomography显示文摘Dear editor,SAR tomography(TomoSAR)[1]as an adavnced technique forms an elevation aperture along the elevation direction.Therefore,it has the ability of resolving layovers,which are common in urban environments.For the moment,TomoSAR is broadly applied to map the urban areas with existence of large quantities of layovers. | Xiaoxiang ZHU Anxi YU Zhen DONG Manqing WU Qi LIU | 2021 | Science China(Information Sciences)2021，64，2： | 1 |
| 9 | Real time estimation of elastic deformation for end-point tracking control of flexible two-link manipulators 显示文摘 | Manq C H | 1992 | The Journal of Dynamic Systems Measurement and Control1992，115，3： | 1 |
| 10 | The Fabrication and Characterization of Polarization Insensitive Semiconductor Optical Amplifier显示文摘An angled facet strained bulk InGaAs SOA has been designed and fabricated. A device with double-layer antireflection coatings had <2dB polarization sensitivity and <0.5dB gain ripple. | Lijuan Yu Weihua Guo Chunlin Han Yong-Zhen Huang Xiaoyu Ma Manqing Tan | 2003 | 光学学报2003，23，S1： | 1 |
| 11 | Impairment of TRPC1-BK complex in diabetic rat coronary artery显示文摘To the Editor:Diabetes mellitus(DM)is a chronic disease that endangers human health and can lead to different complications.[1]Coronary artery,disease is one of the most serious complications in DM patients. | Manqing Sun Lingling Qian Lingfeng Miao Ying Wu Xiaoyu Liu Shipeng Dang Xu Tang Zhenye Zhang Chao Wang Qiang Chai Fu Yi Jianfeng Hao Ruxing Wang | 2022 | Chinese Medical Journal2022，，15： | 0 |
| 12 | A 640×640 ISFET array for detecting cell metabolism显示文摘Ion sensitive field effect transistor(ISFET)devices are highly accurate,convenient,fast and low-cost in the detection of ions and biological macromolecules,such as DNA molecules,antibodies,enzymatic substrates and cellular metabolites.For high-throughput cell metabolism detection,we successfully designed a very large-scale biomedical sensing application specific integrated circuit(ASIC)with a 640×640 ISFET array.The circuit design is highly integrated by compressing the size of a pixel to 7.4×7.4μm^(2)and arranging the layout of even and odd columns in an interdigital pattern to maximize the utilization of space.The chip can operate at a speed of 2.083M pixels/s and the dynamic process of the fluid flow on the surface of the array was monitored through ion imaging.The pH sensitivity is 33±4 mV/pH and the drift rate is 0.06 mV/min after 5 h,indicating the stability and robustness of the chip.Moreover,the chip was applied to monitor pH changes in CaSki cells metabolism,with pH shifting from 8.04 to 7.40 on average.This platform has the potential for continuous and parallel monitoring of cell metabolism in single-cell culture arrays. | Ling Yang Yizheng Huang Zhigang Song Manqing Tan Yude Yu Zhao Li | 2023 | Journal of Semiconductors2023，44，2： | 0 |
| 13 | Simulation of structural design with high coupling efficiency in external cavity semiconductor laser显示文摘For external cavity semiconductor lasers(ECSLs),high coupling efficiency is critical to reducing the linewidth.In this paper,the coupling efficiency between the laser diode and the waveguide grating has been improved,with proposals for its improvement presented,including adding spot-size conversion(SSC)and using a silicon-on-insulator(SOI)waveguide.The results indicate an increase of coupling efficiency from 41.5%to 93.1%,which exhibits an improvement of approximately 51.6%over conventional schemes.The relationship between coupling efficiency and SOI waveguide structures is mainly concerned in this article.These findings provide a new way for the future research of the narrow linewidth of ECSL. | Yangjie Zhang Wentao Guo Di Xiong Xiaofeng Guo Wenyuan Liao Haifeng Liu Weihua Liu Manqing Tan | 2019 | Journal of Semiconductors2019，40，10： | 0 |
| 14 | Artificial Intelligence-enabled contactless sensing for medical diagnosis显示文摘Artificial Intelligence(AI)is an emerging technology which aims to make intelligent machines,especially intelligent computer programs.It can be utilized to enable human intelligence on machines,but the ability of AI does not have to confine itself to biologically observable methods.It can identify hidden relationships,correlations,and trends that may not be apparent in traditional viewpoints.As a result,AI-enabled technologies have achieved significant achievements for medical care including diagnosis,treatment,drug discovery,and healthcare management[1]. | Yan Chen Manqing Wu | 2023 | Medical Review2023，3，3： | 0 |
| 15 | APPLICATION OF ELECTRICAL IMPEDANCE MYOGRAPHY IN CHARACTERIZING CARPAL TUNNEL SYNDROME显示文摘Background:Electrical impedance myography(EIM)is a non-invasive,painless,and easy-to-perform technique for assessing neuromuscular disorders.We evaluated the potential of EIM for quantitatively characterizing carpal tunnel syndrome(CTS).Methods:Healthy subjects and patients with differing severity of CTS underwent EIM measurement of their small hand muscles.A bioelectrical impedance vector analysis(BIVA)method was first applied to display 50-kHz EIM data in a single plot.Results:Patients with more severe CTS had smaller EIM values in the affected muscle.The reactance and phase parameters differed significantly between any two groups(P<0.05).Their accuracy for differentiating between any two adjacent groups was approximately 80%and for other groups was approximately 90%.There was a strong association between EIM and electrophysiology results.Conclusion:BIVA is convenient and helpful for indicating the differences between healthy subjects and CTS patients.These results demonstrate EIM’s potential for quantitatively characterizing patients with CTS. | Chen Lingfen Li Zhao Zhu Yu Yang Ling Hu Shiming Chai Chunlin Tan Manqing Yu Yude Tian Dong | 2019 | 现代电生理学杂志2019，26，B03： | 0 |
| 16 | Apoptotic vesicles rejuvenate mesenchymal stem cells via Rab7-mediated autolysosome formation and alleviate bone loss in aging mice显示文摘Aging skeletons display decreased bone mass,increased marrow adiposity,and impaired bone marrow mesenchymal stem cells(MSCs).Apoptosis is a programmed cell death process that generates a large number of apoptotic vesicles(apoVs).Dysregulated apoptosis has been closely linked to senescence-associated diseases.However,whether apoVs mediate agingrelated bone loss is not clear.In this study,we showed that young MSC-derived apoVs effectively rejuvenated the nuclear abnormalities of aged bone marrow MSCs and restored their impaired self-renewal,osteo-/adipo-genic lineage differentiation capacities via activating autophagy.Mechanistically,apoptotic young MSCs generated and enriched a high level of Ras-related protein 7(Rab7)into apoVs.Subsequently,recipient aged MSCs reused apoV-derived Rab7 to restore autolysosomes formation,thereby contributing to autophagy flux activation and MSC rejuvenation.Moreover,systemic infusion of young MSC-derived apoVs enhanced bone mass,reduced marrow adiposity,and recused the impairment of recipient MSCs in aged mice.Our findings reveal the role of apoVs in rejuvenating aging-MSCs via restoring autolysosome formation and provide a potential approach for treating age-related bone loss. | Fangcao Lei Zhiqing Huang Qianmin Ou Jiaqi Li Manqing Liu Lan Ma Lingping Tan Zhengmei Lin Xiaoxing Kou | 2023 | Nano Research2023，16，1： | 0 |
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