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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia显示文摘 | Francielle Tramontini Gomes de Sousa Cardozo Carla Maísa Camelini Alessandra Mascarello Márcio José Rossi Ricardo José Nunes Célia Regina Monte Barardi Margarida Matos de Mendon?a Cláudia Maria Oliveira Sim?es | 2011 | Antiviral Research2011，，1： | 2 |
| 3 | Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials显示文摘 | Peter M Rothwell Jacqueline F Price F Gerald R Fowkes Alberto Zanchetti Maria Carla Roncaglioni Gianni Tognoni Robert Lee Jill FF Belch Michelle Wilson Ziyah Mehta Tom W Meade | 2012 | The Lancet . 2012 (9826)2012，，： | 1 |
| 4 | Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitisidaea and Maytenus spinosa 显示文摘 | Maria T R de A Carla R L Jose M P | 2010 | Phytochemistry2010，71，1415： | 1 |
| 5 | Telomerase deficiency impairs differentiation of mesenchymal stem cells显示文摘 | Lin Liu Carla M DiGirolamo Paula A.A.S Navarro Maria A Blasco David L Keefe | 2003 | Experimental Cell Research2003，，1： | 1 |
| 6 | Searching for novel cancer chemopreventive plants and their products: the ge- nus Zanthoxylum 显示文摘 | Francesco E Massimo C Maria Carla M | 2011 | Curt Drug Targets2011，12，13： | 1 |
| 7 | In vitro study of N-succinyl chitosan for targeted delivery of 5-aminosalicylic acid to colon显示文摘 | Carla M Maria M Donatella V | 2011 | Carbohydr Polym2011，85，3： | 1 |
| 8 | Searching for novel cancer chemopreventive plants and their products: the genus Zanthoxylum 显示文摘 | Francesco E Massimo C Maria Carla M | 2011 | Current Drug Targets2011，12，13： | 1 |
| 9 | Perceived social support as an offshoot of attachment style显示文摘 | Jo?o M Moreira Maria de Fátima Silva Carla Moleiro Patr??cia Aguiar Micael Andrez Sónia Bernardes Helena Afonso | 2002 | Personality and Individual Differences2002，，3： | 1 |
| 10 | Solid-state nuclear magnetic resonance study of polyurethane/natural fibers composites显示文摘 | Maria I B T Cheila G M Carla R A | 2002 | Journal of Applied Polymer Science2002，85，7： | 1 |
| 11 | Propranolol hydrochloride degradation using La@TiO_(2) functionalized with CMCD显示文摘Propranolol hydrochloride can be considered a persistent and bioaccumulative pharmaceutical in the environment.This drug and its by-products are potentially toxic and have adverse effects,since these compounds have been associated with endocrine-disrupting effects,reproductive deficiencies,embryo abnormalities and pericardial oedema.TiO_(2)–La 0.05%–carboxymethyl-β-cyclodextrin(CMCD)nanoparticles were successfully prepared by a simple two-step method,which consists of sonification and functionalization.The characterization analyses reveal that lanthanum is dispersed on the semiconductor surface,probably forming Ti–O–La bonds,which can induce oxygen vacancies and surface defects that effectively restrain the recombination of photogenerated electron/holes pairs.The efficiency of TiO_(2)–La 0.05%–CMCD samples in degradation of propranolol under UV-light irradiation is higher than that of pristine TiO_(2) within 20 min reaction,probably due to complex formation between theβ-blocker and the oligosaccharide,which allows us to propose a photocatalytic mechanism based on the formation of intermediates and competition of these compounds to the radicals and CMCD cavities. | Gustavo Lopes Colpani Vitor Follmann Santos Rubieli Carla Frezza Zeferino Micheli Zanetti Josiane Maria Muneron de Mello Luciano Luiz Silva Natan Padoin Regina de Fatima Peralta Muniz Moreira Márcio Antônio Fiori Cíntia Soaresc | 2022 | Journal of Rare Earths2022，40，4： | 0 |
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