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16篇 您的检索式:作者名="Mark Norris"
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1GRADE指南:Ⅲ.证据质量分级显示文摘本文介绍证据质量分级的GRADE方法。GRADE将证据质量分为高、中、低和极低四个级别。该分级应用于证据群,而非针对个别研究。系统评价中,质量反映了我们认为效应估计值正确的把握度。对推荐意见而言,质量反映了我们认为效应估计值足以支持某特定推荐的把握度。随机对照试验初定为高质量证据,观察性研究初定为低质量证据。GRADE中所使用的质量一词不只是意味着偏倚风险,还可能受研究结果的不精确性、不一致性和间接性,及发表偏倚的影响。此外,若干因素可增加我们对效应估计值的把握度。GRADE提供了一种系统方法来思考并报告各因素。GRADE将评估证据质量的过程与给出推荐建议的过程分开。推荐强度的判断不仅依赖于证据质量。Howard Balshem Mark Helfanda Holger J.Schunemann Andrew D.Oxman Regina Kunz Jan Brozek Gunn E.Vist Yngve Falck-Ytter Joerg Meerpohl Susan Norris Gordon H.Guyatt GRADE工作组 李幼平 杨晓妍 高霑 2011中国循证医学杂志2011,11,4:128
2GRADE指南:Ⅶ.证据质量评价--不一致性显示文摘本文针对二分类变量结局指标相对(而非绝对)治疗效果的不一致性。证据本身不会因不同研究结果具有一致性而升级,但可能因不一致而降低质量级别。衡量一致性的标准包括点估计值的相似性、可信区间的重叠程度以及统计学判定标准包括异质性检验和I2。系统评价作者应提出并检验少数几个与患者、干预措施、结局指标以及方法学相关的先验假设以探寻异质性来源。当不一致性很大且无法解释时,因不一致性而降低质量级别是恰当的,特别当某些研究显示有显著益处而其他显示无益甚至有害时(而非仅是疗效大与疗效小的比较)。明显的亚组效应可能不可靠。如果亚组效应满足以下条件,其可信度将会增加:基于少数几个有具体方向的先验假设、亚组比较来自研究内而非研究间、交互检验的P值小、结果有生物学意义。Gordon H.Guyatt Andrew D.Oxman Regina Kunz James Woodcock Jan Brozek Mark Helfand Pablo Alonso-Coello Paul Glasziou Roman Jaeschke Elie A.Akl Susan Norris Gunn Vist Philipp Dahm Vijay K.Shukla Julian Higgins Yngve Falck-Ytter Holger J.Schünemann 代表GRADE小组 李幼平 杨晓妍 王莉 蔡羽嘉 陈群飞 2011中国循证医学杂志2011,11,12:33
3GRADE指南:Ⅷ.证据质量评价--间接性显示文摘直接证据来自直接比较我们关注的干预措施用于我们关注的患者人群,并测量患者重要结局的研究。间接证据可由以下4种方式之一产生。第一,患者可能与我们关注的患者不同(适用性一词常用于这类间接性)。第二,所检验的干预措施可能与我们关注的干预措施不同。有关患者和干预措施间接性的决策取决于对生物或社会因素差异是否大到可能使效应尺度出现预期的较大差异的考虑。第三,结果可能有别于最初设定的结局指标——如替代结果本身不重要,但测量之是基于替代结果的变化反映患者重要结局变化这一假设。第四类间接性在概念上与前三类不同,发生于临床医生必须在未经直接比较的两种干预措施间做出选择时。这种情况下比较治疗方案需要特定的统计方法,并根据患者人群、联合干预措施、结局测量指标及备选干预措施试验方法的差异程度,将证据级别降低1或2级。Gordon Guyatt Andrew D.Oxman Regina Kunz James Woodcock Jan Brozek Mark Helfand Pablo Alonso-Coello Yngve Falck-Ytter Roman Jaeschke Gunn Vist Elie A.Akl Piet N Post Susan Norris Joerg Meerpohl Mona Nasser 代表GRADE工作组 李幼平 杨晓妍 李鸿浩 2011中国循证医学杂志2011,11,12:30
4CpG Island methylation in sporadic colorectal cancers and its relationship to microsatellite instability显示文摘Nicholas Hawkins Mark Norrie Kay Cheong Elisa Mokany Su-Lyn Ku Alan Meagher Terence O’connor Robyn Ward 2002Gastroenterology2002,,:2
5Carotid Plaque Pathology: Thrombosis, Ulceration, and Stroke Pathogenesis显示文摘Mark Fisher Annlia Paganini-Hill Aldana Martin Michele Cosgrove James F. Toole Henry J.M. Barnett John Norris 2005Stroke2005,,2:2
6The BT Intranet:Information by Design显示文摘Mark Norris 1999Computer1999,,3:2
7Developing a comprehensive picture of service failure显示文摘Mark Colgate Melissa Norris 2001International Journal of Service Industry Management2001,12,3:1
8Simultaneous separation and quantitation of the major bovine whey proteins including proteose peptone and caseinomacropeptide by reversed-phase high-performance liquid chromatography on polystyrene–divinylbenzene显示文摘David F. Elgar Carmen S. Norris John S. Ayers Mark Pritchard Don E. Otter Kate P. Palmano 2000Journal of Chromatography A2000,,2:1
9Prediction of province-level outbreaks of foot-and-mouth disease in Iran using a zero-inflated negative binomial model显示文摘S Reza Jafarzadeh Michelle Norris Mark C Thurmond 2014Preventive Veterinary Medicine2014,21,34:1
10New Partnerships for Co-delivery of the 2030 Agenda for Sustainable Development显示文摘Partnerships have become a comer stone of contemporary research that recognizes working across disciplines and co-production with intended users as essential to enabling sustainable resilience-building.Furthermore,research that addresses sustainable development challenges brings an urgent need to reflect on the ways that partnerships are supported,and for the disaster risk management and resilience communities,efforts to support realization of the wider 2030 Agenda for sustainable development bring particular pressures.In November 2019,the UK Disasters Research Group(DRG)brought together a number of key stakeholders focused on disaster risk,resilience,and sustainability research relevant to Official DevelopmeAssistance to consider how fit for purpose existing partnership models are for the pace of change required to deliver the priorities of the wider 2030 Agenda.Participants were invited to discuss how research partnerships across three levels(individual and project-based;national and institutional;and international)could be improved based on elements that facilitate robust partnerships and learning from aspects that hinder them.From the discussions,participanls emphasized the importance of effective communication mechanisms in building partnerships,co-designing projects,and establishing shared objectives.Enhanced approaches to addressing equitable partnerships and funding more substantive timelines will be key to responding to the challenges of the 2030 Agenda.Adrian Bucher Andrew Collins Ben Heaven Taylor David Pan Emma Visman James Norris Joel CGill John Rees Mark Felling Marta Tufet Bayona Sonia Cassidy Virginia Murray 2020International Journal of Disaster Risk Science2020,11,5:1
11CpG Island methylation in sporadic colorectal cancers and its relationship to microsatellite instability显示文摘Nicholas Hawkins Mark Norrie Kay Cheong Elisa Mokany Su-Lyn Ku Alan Meagher Terence O’connor Robyn Ward 2002Gastroenterology2002,,5:1
12Modeling stormwater runoff from green roofs with HYDRUS-1D显示文摘Roger Norris Hilten Thomas Mark Lawrence Earnest William Tollner 2008Journal of Hydrology2008,358,34:1
13Carotid Plaque Pathology: Thrombosis, Ulceration, and Stroke Pathogenesis显示文摘Mark Fisher Annlia Paganini-Hill Aldana Martin Michele Cosgrove James F. Toole Henry J.M. Barnett John Norris 2005Stroke2005,,2:1
14GRADE guidelines: 3. Rating the quality of evidence显示文摘Howard Balshem Mark Helfand Holger J. Schünemann Andrew D. Oxman Regina Kunz Jan Brozek Gunn E. Vist Yngve Falck-Ytter Joerg Meerpohl Susan Norris Gordon H. Guyatt 2011Journal of Clinical Epidemiology2011,,4:1
15GRADE guidelines: 3. Rating the quality of evidence显示文摘Howard Balshem Mark Helfand Holger J. Schünemann Andrew D. Oxman Regina Kunz Jan Brozek Gunn E. Vist Yngve Falck-Ytter Joerg Meerpohl Susan Norris Gordon H. Guyatt 2011Journal of Clinical Epidemiology2011,,4:1
16Modeling stormwater runoff from green roof with HYDRUS-1D显示文摘Roger Norris Hilten Thomas Mark Lawrence Earnest William Tollner 2008Journal of Hydrology2008,,358:1
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