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| 1 | Management of autoimmune hepatitis:Focus on pharmacologic treatments beyond corticosteroids显示文摘In autoimmune hepatitis, patients who are intolerant or with toxicity experience, non-responders, relapsers or refractory are challenging. Non-standard drugs are being tried to preemptively avoid corticosteroid-related side effects. Prognosis and quality of life of life rely on treatment optimization. Recently, emergence of powerful immunosuppressive agents, mainly from liver transplantation, challenged the supremacy of the corticosteroid regime and promise greater immunosuppression than conventional medications, offer site-specific actions and satisfactory patient tolerance. Successes in experimental models of related diseases have primed these molecular interventions. We performed a literature review on alternative treatments. Azatioprine intolerance is the principal indication for mycophenolate use butit can be used as a front-line therapy. Cyclosporine A and tacrolimus have been tested for non-responders or relapsers. Rituximab may be used as salvage therapy. Anti-tumor necrosis factor-alpha agents may be used for incomplete responses or non-responders. Methotrexate is possibly an alternative for induction of remission and maintenance in refractory patients. Cyclophosphamide has been included in the induction regimen with corticosteroids. Ursodeoxycholic acid action is mainly immunomodulatory. Non-standard treatments are coming slowly to the attention, but its use should be cautious performed by experienced centers. | Marta Casal Moura Rodrigo Liberal Hélder Cardoso Ana Maria Horta e Vale Guilherme Macedo | 2014 | World Journal of Hepatology2014，6，6： | 2 |
| 2 | Balancing cell adhesion and Wnt signaling, the key role of β-catenin显示文摘 | Felix H Brembeck Marta Rosário Walter Birchmeier | 2006 | Current Opinion in Genetics & Development2006，，1： | 2 |
| 3 | FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex显示文摘 | Marta Muzio Arul M Chinnaiyan Frank C Kischkel Karen O’Rourke Andrej Shevchenko Jian Ni Carsten Scaffidi James D Bretz Mei Zhang Reiner Gentz Matthias Mann Peter H Krammer Marcus E Peter Vishva M Dixit | 1996 | Cell1996，，： | 1 |
| 4 | Bacteria starter cultures for meat fermentation显示文摘 | H Marta M Josep | 1997 | Food Chemistry1997，，59： | 1 |
| 5 | Comparative sen-sitivity of urinary CY FRA 21-1,urinary bladder cancerantigen,tissue polypeptide antigen and NMP22 to de-tect bladder cancer显示文摘 | Marta SE Enrique H Julian M | 1999 | J Urol1999，162，： | 1 |
| 6 | A specific real-time quanlilative PCR detection system for event MON810 in maize YieldGard? based on the 3-transgene integration sequence显示文摘 | Marta H Maria P Teresa E | 2003 | Transgenic Research2003，12，： | 1 |
| 7 | Comparative sensitivity of urinary CYFRA21-1, urinary bladder cancer antigen, tissue polypeptide antigen and NMP22 to detect bladder cancer 显示文摘 | Marta SC Enrique H Julian M | 1999 | J Urol1999，162，： | 1 |
| 8 | Functional characterization of E-and P-cadherin in invasive breast cancer cells显示文摘 | David S Jose P Marta H | 2009 | BMC Canc- er2009，9，： | 1 |
| 9 | Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobaeterium tuberculosis molecular epidemiology studies显示文摘 | Noelia AR Miguel M Marta H | 2008 | BMC Microbiology2008，8，： | 1 |
| 10 | Bacterial starter c ultures for meat fermentation显示文摘 | Marta H Josep NM | 1997 | Food Ch em1997，59，： | 1 |
| 11 | Mycotoxin production in major crops as influenced by growing, harvesting, storage and processing, with emphasis on the achievement of food safety objectives 显示文摘 | Pitt JI Marta H | 2013 | Food Control2013，32，： | 1 |
| 12 | Bacteria starter cultures for meat fermentation显示文摘 | MARTA H JOSEP M | 1997 | Food Chemistry1997，59，： | 1 |
| 13 | Current methodology for detection,identification and quantification of genetically modified organisms显示文摘 | MARTA H DAVID R L ALEJANDRO F | 2005 | Current Analytical Chemistry2005，1，2： | 1 |
| 14 | Bromobenzene flame retardants in the great lakes atmosphere 显示文摘 | Marta V Yuning M Ronald A H | 2012 | Envlmn Sci Technol2012，46，： | 1 |
| 15 | Bacteria starter cultures for meat fermentation显示文摘 | Marta H Josep M | 1997 | Food Chemistry1997，59，： | 1 |
| 16 | Regulation and inhibition of collagenase expression by long - wavelength ultraviolet radiation in cultured human skin fibroblasts显示文摘 | Marta P Tiffani H Haili L | 1995 | Photochem and Photobiol1995，62，： | 1 |
| 17 | Comparative Analysis of Different Flowcytometry Bassed im Munophenotypic Methods Fortheanalysis of CD59 and CD55 Expression on Major Peripheral Blood Cell Subsets显示文摘 | PILAR M H MARTA M A JULIA ALMEIDA | 2002 | Clin Cytometry2002，50，： | 1 |
| 18 | Adjustments on the cryopreservation condi tions reduce the incidence of boar ejaculates with poor sperm freezability 显示文摘 | Marta H Jordi R | 2007 | Theriogenology2007，67，： | 1 |
| 19 | The fairness of PAYT systemssome guidelines for decision-makers显示文摘 | Marta B Kenneth H | 2008 | Waste Man-agement2008，28，： | 1 |
| 20 | Development of a framework for fire risk assessment using remote sensing and geographic information system technologies显示文摘 | Emilio Chuvieco Inmaculada Aguado Marta Yebra Héctor Nieto Javier Salas M. Pilar Martín Lara Vilar Javier Martínez Susana Martín Paloma Ibarra Juan de la Riva Jaime Baeza Francisco Rodríguez Juan R. Molina Miguel A. Herrera Ricardo Zamora | 2008 | Ecological Modelling2008，，1： | 1 |
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