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| 1 | Comparison of effect of granules and herbs of Bu-Shen-Yi-Qi-Tang on airway inflammation in asthmatic mice显示文摘 | Wei Ying Lyu Yubao Li Mihui Luo Qingli Sun Jing Liu Feng Lin Yanhua Chen Meixia Mammat Nurahmat Muhammadian Abduwaki Dong Jingcheng | 2014 | Chinese Medical Journal2014，，22： | 3 |
| 2 | Caspase-3 mRNA expression in rats with apoptosis of retinal photoreceptor cells显示文摘BACKGROUND: Apoptosis of retinal photoreceptor cells is a commonly pathological characteristic of various eye diseases, while caspase-3 is an important regulating gene and plays a key role in apoptosis. OBJECTIVE: To measure the expression of caspase-3 mRNA in rats with apoptosis of retinal photoreceptor cells by using real-time fluorescent quantitative polymerase chain reaction and compare with those of the normal rats. DESIGN: Randomized controlled animal study. SETTING: Zhongshan Ophthalmological Center of Sun Yat-sen University. MATERIALS: A total of 36 female SD rats of 50 days old and clean grade and weighing (150±10) g were provided by Experimental Animal Center of Northern Area of Sun Yat-sen University. All rats were randomly divided into normal control group (n =6) and N-methyl-N-nitrosourea (MNU) group (n =30), and they were observed at 12 hours, 1, 2, 3 and 5 days after model establishment, with 6 rats at each time point. METHODS: The experiment was carried out at Zhongshan Ophthalmological Center, Key Laboratory of Ophthalmology by State Ministry of Education from March to December 2004. Rats in the normal control group were intraperitoneally injected with saline and rats in the MNU group were intraperitoneally injected with 40 mg/kg MNU. And then, retinal photoreceptor injured models were established. At 12 hours, 1, 2, 3 and 5 days after model establishment, the rats were sacrificed for enucleating right eyeballs, isolating retina immediately and extracting total RNA. The expression of caspase-3 mRNA in retina was measured with real-time fluorescent quantitative polymerase chain reaction. MAIN OUTCOME MEASURES: Expression of caspase-3 mRNA in retina of rats in the two groups. RESULTS: A total of 36 SD rats were involved in the final analysis. The expressions of caspase-3 mRNA in the rat retina of both groups at the five time points (12 hours, 1, 2, 3 and 5 days) after model establishment were 1.52×105, 18.35×105, 25.14×105, 29.25×105, 13.72×105 and 12.24×105, respectively. The expression of caspase-3 mRNA in the MNU group increased after 12 hours of intraperitoneal injection, and rose to the top on the 2nd day, which was 19 times as many as that of the normal control group. Then, it decreased gradually and was still 8 times as many as that of the normal control group on the 5th day. CONCLUSION: The expression of caspase-3 mRNA is related to apoptosis of retinal photoreceptor cells, while caspase-3 plays an important role in occurrence and development of apoptosis of retinal photoreceptor cells. | Jinmao Chen Jinnan Yang Shaochun Lin Yue Zhang Meixia An Shixing Hu | 2007 | Neural Regeneration Research2007，2，5： | 1 |
| 3 | A target analogue imprinted polymer for the recognition of antiplatelet active ingredients in Radix Salviae Miltiorrhizae by LC/MS/MS显示文摘 | Meixia Huang Wensheng Pang Jing Zhang Siding Lin Juan Hu | 2011 | Journal of Pharmaceutical and Biomedical Analysis2011，，： | 1 |
| 4 | Ultrahigh pressure extraction of lignan compounds from Dysosma versipellis and purification by high-speed counter-current chromatography显示文摘 | Qing Zhu Feng Liu Meixia Xu Xiaojing Lin Xiao Wang | 2012 | Journal of Chromatography B2012，，： | 1 |
| 5 | Greenspace’s value orientations of ecosystem service and socioeconomic service in China显示文摘Background:Natural ecosystems provide necessary services for human beings,including ecosystem service values(ESVs)and socioeconomic service values(SSVs).The value orientations of ESVs and SSVs are mainly related to people’s interaction with nature.This study reclassified greenspace from a perspective of exposed and non-exposed greenspace based on the level of interaction by people and greenspace.We applied an expert questionnaire to survey the SSVs value orientations of forestland,grassland,wetland,and water bodies,and quantitatively compared the value orientations between the ESVs and SSVs of greenspace in China.Result:(1)The values of exposed greenspace were relatively far higher than nonexposed greenspace,as it had both ESVs and SSVs.(2)The forestland and grassland had relatively high ESVs and SSVs,and are the priority for both the exposed and non-exposed greenspace.(3)Wetland had relatively high ESVs but low SSVs,which was unpopular for exposed greenspace.(4)The ESVs and SSVs of water body were relatively balanced.Conclusion:Greenspace had both ESVs and SSVs when they are exposed to human.Our study provided an innovative perspective to explore the value orientations of greenspace,which provides an actionable scientific basis for greenspace planning,design and construction in human habitat. | Xia Yao Tao Lin Shoukai Sun Guoqin Zhang Hao Zhou Laurence Jones Wenhui Liu Yiyi Huang Meixia Lin Junmao Zhang Yuan Chena Hong Ye | 2022 | Ecosystem Health and Sustainability2022，8，1： | 1 |
| 6 | Zooplankton community size-structure change and mesh size selection under the thermal stress caused by a power plant in a semi-enclosed bay显示文摘Zooplankton samples were collected using 505, 160 and 77 μm mesh nets around a power plant during four seasons in 2011. We measured total length of zooplankton and divided zooplankton into seven size classes in order to explore how zooplankton community size-structure might be altered by thermal discharge from power plant. The total length of zooplankton varied from 93.7 to 40 074.7 μm. The spatial distribution of mesozooplankton(200-2 000 μm) populations were rarely affected by thermal discharge, while macro-(2 000-10 000 μm)and megalo-zooplankton(>10 000 μm) had an obvious tendency to migrate away from the outfall of power plant.Thus, zooplankton community tended to become smaller and biodiversity reduced close to power plant.Moreover, we compared the zooplankton communities in three different mesh size nets. Species richness,abundance, evenness index and Shannon-Wiener diversity index of the 505 μm mesh size were significantly lower than those recorded from the 160 and 77 μm mesh size. Average zooplankton abundance was highest in the 77 μm mesh net((27 690.0±1 633.7) ind./m^3), followed by 160 μm mesh net((9 531.1±1 079.5) ind./m^3), and lowest in 505 μm mesh net((494.4±104.7) ind./m^3). The ANOSIM and SIMPER tests confirmed that these differences were mainly due to small zooplankton and early developmental stages of zooplankton. It is the first time to use the 77 μm mesh net to sample zooplankton in such an environment. The 77 μm mesh net had the overwhelming abundance of the copepod genus Oithona, as an order of magnitude greater than recorded for 160 μm mesh net and 100% loss through the 505 μm mesh net. These results indicate that the use of a small or even multiple sampling net is necessary to accurately quantify entire zooplankton community around coastal power plant. | Qianwen Shao Yifeng Zhu Meixia Dai Xia Lin Chengxu Zhou Xiaojun Yan | 2020 | Acta Oceanologica Sinica2020，39，8： | 0 |
| 7 | A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots显示文摘Astragalus membranaceus var.mongholicus(AMM),a member of the Leguminosae,is one of the most important medicinal plants worldwide.The dried roots of AMM have a wide range of pharmacological effects and are a traditional Chinese medicine.Here,we report the first chromosome-level reference genome of AMM,comprising nine pseudochromosomes with a total size of 1.47 Gb and 27868 protein-encoding genes.Comparative genomic analysis reveals that AMM has not experienced an independent wholegenome duplication(WGD)event after the WGD event shared by the Papilionoideae species.Analysis of long terminal repeat retrotransposons suggests a recent burst of these elements at approximately 0.13 million years ago,which may explain the large size of the AMM genome.Multiple gene families involved in the biosynthesis of triterpenoids and flavonoids were expanded,and our data indicate that tandemduplication has been the main driver for expansion of these families.Among the expanded families,the phenylalanine ammonia-lyase gene family was primarily expressed in the roots of AMM,suggesting their roles in the biosynthesis of phenylpropanoid compounds.The functional versatility of 2,3-oxidosqualene cyclase genes in cluster Ⅲ may play a critical role in the diversification of triterpenoids in AMM.Our findings provide novel insights into triterpenoid and flavonoid biosynthesis and can facilitate future research on the genetics and medical applications of AMM. | Yi Chen Ting Fang He Su Sifei Duan Ruirui Ma Ping Wang Lin Wu Wenbin Sun Qichen Hu Meixia Zhao Lianjun Sun Xuehui Dong | 2023 | Plant Communications2023，4，2： | 0 |
| 8 | A Vision-aided Localization and Geo-registration Method for Urban ARGIS Based on 2D Maps显示文摘Augmented Reality Geographic Information System(ARGIS) applications can only provide users accurate content services with a highly precise geo-registration.However,the absolute 6DOF(Degree of Freedom) pose provided by the portable sensors is usually inaccurate in urban outdoors,resulting in poorly geo-registration accuracy for ARGIS applications.Aiming at this issue,an automatic vision-aided localization method based on the 2D map is proposed to improve the initial localization accuracy of the portable sensors,and an overall geo-registration optimization framework for outdoor ARGIS is proposed.Based on the initial pose provided by the sensors,the basic principles of the vision-aided localization method are expounded in detail.The experimental results show that the proposed method can effectively correct the initial pose obtained by the pose sensors,and improve the geo-registration accuracy of outdoor ARGIS applications ultimately. | Chen DENG Xiong YOU Weiwei ZHANG Meixia ZHI Diao LIN Wang XU | 2022 | Journal of Geodesy and Geoinformation Science2022，5，3： | 0 |
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