|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 《教育技术的含义》译文显示文摘教育技术是通过创造、使用、管理适当的技术性的过程和资源,以促进学习和改善绩效的研究与符合道德规范的实践。这是美国教育传播与技术协会(AECT)2004年在《教育技术的含义》文献中提出的关于教育技术概念的新定义。该文献包括背景、定义、定义的元素、与教育技术概念的关系、与绩效技术概念的关系、定义背后的假设、目的和受众、历史上的早期定义、结论、参考文献十个部分。 | Michael Molenda Rhonda Robinson 彭绍东 刘嘉 蒋玲玲 刘光义 王斌 | 2005 | 现代教育技术2005，15，3： | 9 |
| 2 | Competition between human cells by entosis显示文摘人的癌由被知道为营养素和生长因素间接地竞争的肿瘤房间的复杂混合物组成。肿瘤房间是否能也直接竞争,例如由对手的消除,不被知道。这里,我们证明人的房间能直接由称为 entosis 的吞没的机制竞争。由 entosis,当时,房间被吞没,或吃活,并且随后经历房间死亡。我们发现吞没的身份(“ winner”) 并且吞没(“ loser”) 房间被 RhoA 和肌动球朊控制的机械 deformability 支配,有高 deformability 的肿瘤房间在此优先地吞没并且 outcompete 有在异构的人口的低 deformability 的附近的房间。我们进一步发现那激活的 Kras 并且 Rac 发信号由 downregulating 给予获胜者地位到房间可收缩的肌浆球蛋白,允许最后经历房间死亡的附近的房间的成为主观。最后,我们计算 cell-in-cell 形成的精力风景,表明那一机械在获胜者和输家房间之间微分被要求让 entosis 继续。这些数据在发生在人的肿瘤的哺乳动物的房间定义竞争的机制。 | Qiang Sun Tianzhi Luo Yixin Ren Oliver Florey Senji Shirasawa Takehiko Sasazuki Douglas N Robinson Michael Overholtzer | 2014 | Cell Research2014，24，11： | 8 |
| 3 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 6 |
| 4 | Stratification of outcomes for mucinous appendiceal adenocarcinoma with peritoneal metastasis by histological grade显示文摘AIM To investigate the importance of a three-tiered histologic grade on outcomes for patients with mucinous appendiceal adenocarcinoma(MAA).METHODS Two hundred and sixty-five patients with MAA undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy were identified from a prospective database from 2004 through 2014. All pathology was reviewed by our gastrointestinal subspecialty pathologists and histological grade was classified as well-differentiated, moderately differentiated, and poorly differentiated. Survival analysis was performed using Cox proportional hazards regression.RESULTS There were 201(75.8%) well-, 45(16.9%) moderatelyand 19(7.2%) poorly-differentiated tumors. Histological grade significantly stratified the 5-year overall survival(OS), 94%, 71% and 30% respectively(P < 0.001) as well as the 5-year disease-free survival(DFS) 66%, 21% and 0%, respectively(P < 0.001). Independent predictors of DFS included tumor grade(HR = 1.78, 95%CI: 1.21-2.63, P = 0.008), lymph node involvement(HR = 0.33, 95%CI: 0.11-0.98, P < 0.02), previous surgical score(HR = 1.31, 95%CI: 1.1-1.65, P = 0.03) and peritoneal carcinomatosis index(PCI)(HR = 1.05, 95%CI: 1.02-1.08, P = 0.002). Independent predictors of OS include tumor grade(HR = 2.79, 95%CI: 1.26-6.21, P = 0.01), PCI(HR = 1.10, 95%CI: 1.03-1.16, P = 0.002), and complete cytoreduction(HR = 0.32, 95%CI: 0.11-0.92, P = 0.03). Tumor grade and PCI were the only independent predictors of both DFS and OS. Furthermore, histological grade and lymphovascular invasion stratified the risk of lymph node metastasis into a low(6%) and high(40%) risk groups. CONCLUSION Our data demonstrates that moderately differentiated MAA have a clinical behavior and outcome that is distinct from well-and poorly-differentiated MAA. The threetier grade classification provides improved prognostic stratification and should be incorporated into patient selection and treatment algorithms. | Travis Edward Grotz Richard E Royal Paul F Mansfield Michael James Overman Gary N Mann Kristen Ashlee Robinson Karen A Beaty Safiea Rafeeq Auerlio Matamoros Michelle W Taggart Keith Francis Fournier | 2017 | World Journal of Gastrointestinal Oncology2017，9，9： | 2 |
| 5 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 2 |
| 6 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 7 | Prospective Randomized Controlled Trial of an Intramedullary Nail Versus Dynamic Screw and Plate for Intertrochanteric Fractures of the Femur显示文摘 | Christopher I. Adams C. Michael Robinson Charles M. Court-Brown Margaret M. McQueen | 2001 | Journal of Orthopaedic Trauma2001，，6： | 2 |
| 8 | 烟酰胺和N-乙酰葡萄糖胺改善色斑效果观察显示文摘目的:比较含烟酰胺和N-乙酰葡萄糖胺的护肤品在改善色素沉着方面的效果。方法:双盲、基质对照人体试验。采用REAL3.0系统采集所有图像,用相关软件分析色斑面积百分比、L*a*b值、黑素相关的色斑面积百分比、平均黑素含量(灰度)和黑素相关的皮肤颜色均匀度;Chromameter测量非色斑部位皮肤颜色改变;由皮肤科专家分析使用护肤品前后照片改善情况和受试者自我比较进行主观评价。结果:与基质相比,含烟酰胺和N-乙酰葡萄糖胺的护肤品可以抑制色斑面积的增加,减轻紫外线引起的肤色加深和肤色不均匀。结论:正常人皮肤对含烟酰胺和N-乙酰葡萄糖胺的护肤品有良好的耐受性,与基质相比,该护肤品有一定的减轻色素沉着的效果。 | 吴艳 仲少敏 Joe Kaczvinsky 赵俊郁 乔圆 邓琳 Chieko Soh Cindy Berge Michael Marmor Donald Bissett Larry Robinson 朱学骏 | 2007 | 临床皮肤科杂志2007，36，10： | 2 |
| 9 | Early Fluid Resuscitation Reduces Morbidity Among Patients With Acute Pancreatitis显示文摘 | Matthew G. Warndorf Jane T. Kurtzman Michael J. Bartel Mougnyan Cox Todd Mackenzie Sarah Robinson Paul R. Burchard Stuart R. Gordon Timothy B. Gardner | 2011 | Clinical Gastroenterology and Hepatology2011，，8： | 1 |
| 10 | Concordance of the Toxicity of Pharmaceuticals in Humans and in Animals显示文摘 | Harry Olson Graham Betton Denise Robinson Karluss Thomas Alastair Monro Gerald Kolaja Patrick Lilly James Sanders Glenn Sipes William Bracken Michael Dorato Koen Van Deun Peter Smith Bruce Berger Allen Heller | 2000 | Regulatory Toxicology and Pharmacology2000，，1： | 1 |
| 11 | Biodegradable Implants for Sustained Drug Release in the Eye显示文摘 | Susan S. Lee Patrick Hughes Aron D. Ross Michael R. Robinson | 2010 | Pharmaceutical Research2010，，10： | 1 |
| 12 | Dry deposition of gaseous elemental mercury to plants and soils using mercury stable isotopes in a controlled environment显示文摘 | Andrew P. Rutter James J. Schauer Martin M. Shafer Joel E. Creswell Michael R. Olson Michael Robinson Ryan M. Collins Andrew M. Parman Tanya L. Katzman Justin L. Mallek | 2010 | Atmospheric Environment2010，，4： | 1 |
| 13 | Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis显示文摘 | David H. Adams Jeffrey J. Popma Michael J. Reardon Steven J. Yakubov Joseph S. Coselli G. Michael Deeb Thomas G. Gleason Maurice Buchbinder James Hermiller Neal S. Kleiman Stan Chetcuti John Heiser William Merhi George Zorn Peter Tadros Newell Robinson Ge | 2014 | The New England Journal of Medicine2014，，19： | 1 |
| 14 | The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Timothy C. Ryken Michael McDermott Paula D. Robinson Mario Ammirati David W. Andrews Anthony L. Asher Stuart H. Burri Charles S. Cobbs Laurie E. Gaspar Douglas Kondziolka Mark E. Linskey Jay S. Loeffler Minesh P. Mehta Tom Mikkelsen Jeffrey J. Olson Nina | 2010 | Journal of Neuro - Oncology2010，，1： | 1 |
| 15 | The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Laurie E. Gaspar Minesh P. Mehta Roy A. Patchell Stuart H. Burri Paula D. Robinson Rachel E. Morris Mario Ammirati David W. Andrews Anthony L. Asher Charles S. Cobbs Douglas Kondziolka Mark E. Linskey Jay S. Loeffler Michael McDermott Tom Mikkelsen Jeffre | 2010 | Journal of Neuro - Oncology2010，，1： | 1 |
| 16 | The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Steven N. Kalkanis Douglas Kondziolka Laurie E. Gaspar Stuart H. Burri Anthony L. Asher Charles S. Cobbs Mario Ammirati Paula D. Robinson David W. Andrews Jay S. Loeffler Michael McDermott Minesh P. Mehta Tom Mikkelsen Jeffrey J. Olson Nina A. Paleologos | 2010 | Journal of Neuro - Oncology2010，，1： | 1 |
| 17 | The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Mark E. Linskey David W. Andrews Anthony L. Asher Stuart H. Burri Douglas Kondziolka Paula D. Robinson Mario Ammirati Charles S. Cobbs Laurie E. Gaspar Jay S. Loeffler Michael McDermott Minesh P. Mehta Tom Mikkelsen Jeffrey J. Olson Nina A. Paleologos Roy | 2010 | Journal of Neuro - Oncology2010，，1： | 1 |
| 18 | Believability and the Press显示文摘 | Robinson Michael J Kohut Andrew | 1988 | Public Opinion Quarterly1988，，2： | 1 |
| 19 | Market entry and exit by biotech and device companies funded by venture capital显示文摘 | Burns Lawton R Housman Michael G Robinson Charles A | | 0，，01： | 1 |
| 20 | Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities显示文摘 | Halil Uzuner Rudolf Bauer Tai-Ping Fan De-an Guo Alberto Dias Hani El-Nezami Thomas Efferth Elizabeth M. Williamson Michael Heinrich Nicola Robinson Peter J. Hylands Bruce M. Hendry Yung-Chi Cheng Qihe Xu | 2012 | Journal of Ethnopharmacology2012，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员