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| 1 | J波综合征专家上海共识:概念与认知的更新显示文摘序言
J波综合征(J wave syndromes,JW Ss),包括Brugada综合征(BrS)和早复极综合征(ERS)。有关Br S,在2000年和2004年分别举行了BrS的国际专家共识会议;有关ERS,直到2013年才在原发性遗传性心律失常专家共识里做出了针对ERS的指导意见。在2015年4月,心脏节律协会(HRS)、欧洲心脏节律协会(EHRA)和亚洲太平洋心脏节律协会(APHRS)的主要专家成员组成的工作组聚集在中国上海,审查了有关JWSs的新证据, | Charles Antzelevitch 严干新 Michael J.Ackerman Martin Borggrefe Domenico Corrado 郭继鸿(审核) Ihor Gussak Can Hasdemir Minoru Horie Heikki Huikuri 马长生 Hiroshi Morita Gi-Byoung Nam Frederic Sacher Wataru Shimizu Sami Viskin Arthur A.M.Wilde 刘霄燕(译) 揭起强(译) 吴林(审核) | 2016 | 临床心电学杂志2016，25，3： | 21 |
| 2 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 3 | Neural EGF-like protein 1(NELL-1):Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine显示文摘Bone tissue regeneration holds the potential to solve both osteoporosis and large skeletal defects,two problems associated with significant morbidity.The differentiation of mesenchymal stem cells into the osteogenic lineage requires a specific microenvironment and certain osteogenic growth factors.Neural EGF Like-Like molecule 1(NELL-1)is a secreted glycoprotein that has proven,both in vitro and in vivo,to be a potent osteo-inductive factor.Furthermore,it has been shown to repress adipogenic differentiation and inflammation.NELL-1 can work synergistically with other osteogenic factors such as Bone Morphogenic Protein(BMP)2 and9,and has shown promise for use in tissue engineering and as a systemically administered drug for the treatment of osteoporosis.Here we provide a comprehensive up-to-date review on the molecular signaling cascade of NELL-1 in mesenchymal stem cells and potential applications in bone regenerative engineering. | Mikhail Pakvasa Alex Alverdy Sami Mostafa Eric Wang Lucy Fu Alexander Li Leonardo Oliveira Aravind Athiviraham Michael J.Lee Jennifer Moriatis Wolf Tong-Chuan He Guillermo A.Ameer Russell R.Reid | 2017 | Genes & Diseases2017，4，3： | 13 |
| 4 | 3-D bioprinting technologies in tissue engineering and regenerative medicine:Current and future trends显示文摘Advances in three-dimensional(3D)printing have increased feasibility towards the synthesis of living tissues.Known as 3D bioprinting,this technology involves the precise layering of cells,biologic scaffolds,and growth factors with the goal of creating bioidentical tissue for a variety of uses.Early successes have demonstrated distinct advantages over conventional tissue engineering strategies.Not surprisingly,there are current challenges to address before 3D bioprinting becomes clinically relevant.Here we provide an overview of 3D bioprinting technology and discuss key advances,clinical applications,and current limitations.While 3D bioprinting is a relatively novel tissue engineering strategy,it holds great potential to play a key role in personalized medicine. | Elliot S.Bishop Sami Mostafa Mikhail Pakvasa Hue H.Luu Michael J.Lee Jennifer Moriatis Wolf Guillermo A.Ameer Tong-Chuan He Russell R.Reid | 2017 | Genes & Diseases2017，4，4： | 10 |
| 5 | 为恶意、良性的胆汁的苛评的治疗的充分盖住的自我可扩充的金属 stents显示文摘 AIM:To present a series of covered self-expandable metal stents(CSEMS) placed for different indications and to evaluate the effectiveness,complications and extractability of these devices.METHODS:We therefore retrospectively reviewed the courses of patients who received CSEMS due to malignant as well as benign biliary strictures and postsphincterotomy bleeding in our endoscopic unit between January 2010 and October 2011.RESULTS:Twenty-six patients received 28 stents due to different indications(20 stents due to malignant biliary strictures,six stents due to benign biliary strictures and two stents due to post-sphincterotomy bleeding).Biliary obstruction was relieved in all cases,regardless of the underlying cause.Hemostasis could be achieved in the two patients who received the stents for this purpose.Complications occurred in five patients(18%).Two patients(7%) developed cholecystitis,stents dislocated/migrated in other two patients(7%),and in one patient(3.6%) stent occlusion was documented during the study period.Seven stents were extracted endoscopically.Removal of stents was easily possible in all cases in which it was desired using standard forceps.Twelve patients underwent surgery with pylorus preserving duodenopancreatectomy.In all patients stents could be removed during the operation without difficulties.CONCLUSION:Despite the higher costs of these devices,fully covered self-expanding metal stents may be suitable to relief biliary obstruction due to bile duct stenosis,regardless of the underlying cause.CSEMS may also represent an effective treatment strategy of severe post-sphincterotomy bleeding,not controlled by other measures. | Ahmed Abdel Samie Stephan Dette Ulrich Vhringer Michael Stumpf Karolin Kopischke Lorenz Theilmann | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 5 |
| 6 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 7 | J-Point Elevation in Survivors of Primary Ventricular Fibrillation and Matched Control Subjects显示文摘 | Raphael Rosso Evgeni Kogan Bernard Belhassen Uri Rozovski Melvin M. Scheinman David Zeltser Amir Halkin Arie Steinvil Karin Heller Michael Glikson Amos Katz Sami Viskin | 2008 | Journal of the American College of Cardiology2008，，15： | 2 |
| 8 | Determination of ractopamine in animal tissues by liquid chromatography-fluorescence and liquid chromatography/tandem mass spectrometry显示文摘 | Eshaq (Isaac) Shishani Sin Chii Chai Sami Jamokha Gene Aznar Michael K Hoffman | 2003 | Analytica Chimica Acta2003，，1： | 1 |
| 9 | The Natural History of Surgically Treated Primary Adenocarcinoma of the Appendix显示文摘 | Samy S. Nitecki Bruce G. Wolff Richard Schlinkert Michael G. Sarr | 1994 | Annals of Surgery1994，，1： | 1 |
| 10 | TiON and TiON-Ag sputtered surfaces leading to bacterial inactivation under indoor actinic light显示文摘 | Sami Rtimi Oualid Baghriche Rosendo Sanjines Cesar Pulgarin Michael Bensimon John Kiwi | 2013 | Journal of Photochemistry & Photobiology, A: Chemistry2013，，： | 1 |
| 11 | Fertilizer and irrigation effects on forage protein and energy production under semi-arid conditions of Pakistan显示文摘 | Sami Ul-Allah Asif Ali Khan Thomas Fricke Andreas Buerkert Michael Wachendorf | 2014 | Field Crops Research2014，，： | 1 |
| 12 | Colonoscopy in octogenarians: a prospective outpatient study显示文摘 | Frank J Lukens David S Loeb Victor I Machicao Sami R Achem Michael F Picco | 2002 | The American Journal of Gastroenterology2002，，7： | 1 |
| 13 | Arteriovenous malformation: a potential cause of ischaemic colitis显示文摘 | Mohammad Sami El Muhtaseb Emre Gorgun Michael Liu | 2013 | ANZ J Surg (-)2013，，1： | 1 |
| 14 | Prospective, Controlled Tandem Endoscopy Study of Narrow Band Imaging for Dysplasia Detection in Barrett’s Esophagus显示文摘 | Herbert C. Wolfsen Julia E. Crook Murli Krishna Sami R. Achem Kenneth R. Devault Ernest P. Bouras David S. Loeb Mark E. Stark Timothy A. Woodward Lois L. Hemminger Frances K. Cayer Michael B. Wallace | 2008 | Gastroenterology2008，，： | 1 |
| 15 | Prospective, Controlled Tandem Endoscopy Study of Narrow Band Imaging for Dysplasia Detection in Barrett’s Esophagus显示文摘 | Herbert C. Wolfsen Julia E. Crook Murli Krishna Sami R. Achem Kenneth R. Devault Ernest P. Bouras David S. Loeb Mark E. Stark Timothy A. Woodward Lois L. Hemminger Frances K. Cayer Michael B. Wallace | 2008 | Gastroenterology2008，，1： | 1 |
| 16 | TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation显示文摘 | Xiping Cheng Jie Jin Lily Hu Dongbiao Shen Xian-ping Dong Mohammad A. Samie Jayne Knoff Brian Eisinger Mei-ling Liu Susan M. Huang Michael J. Caterina Peter Dempsey Lowell Evan Michael Andrzej A. Dlugosz Nancy C. Andrews David E. Clapham Haoxing Xu | 2010 | Cell2010，，2： | 1 |
| 17 | Determination of ractopamine in animal tissues by liquid chromatography-fluorescence and liquid chromatography/tandem mass spectrometry显示文摘 | Eshaq (Isaac) Shishani Sin Chii Chai Sami Jamokha Gene Aznar Michael K Hoffman | 2003 | Analytica Chimica Acta2003，，1： | 1 |
| 18 | A method- ology for solving physiologically based pharmacokinetic models without the use of simulation softwares 显示文摘 | Sami Haddad Michael Pelekis Kannan Krishnan | 1996 | Toxicology Letters1996，，： | 1 |
| 19 | Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation显示文摘 | Michael Aviram Mira Rosenblat Diana Gaitini Samy Nitecki Aaron Hoffman Leslie Dornfeld Nina Volkova Dita Presser Judith Attias Harley Liker Tony Hayek | 2003 | Clinical Nutrition2003，，3： | 1 |
| 20 | Intravenous dexmedetomidine infusion for labour analgesia in patient with preeclampsia显示文摘 | Sami A Abu-Halaweh Abdel-Kareem S Al Oweidi Hadeel Abu-Malooh Majd Zabalawi Fawaz Alkazaleh Hamdi Abu-Ali Michael AE Ramsay | 2009 | European Journal of Anaesthesiology2009，，1： | 1 |
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