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| 1 | Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing显示文摘COVID-19,caused by SARS-CoV-2[1,2],has been contained in China through stringent non-pharmaceutical interventions.Border control and quarantine have effectively prevented the virus from being spread by infected travellers,but the risk of resurgence caused by other routes of introduction and transmission remains unclear,and current strategies to prevent resurgence could be flawed.Since July,SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China[3,4].However,there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission.Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing. | Xinghuo Pang Lili Ren Shuangsheng Wu Wentai Ma Jian Yang Lin Di Jie Li Yan Xiao Lu Kang Shichang Du Jing Du Jing Wang Gang Li Shuguang Zhai Lijuan Chen Wenxiong Zhou Shengjie Lai Lei Gao Yang Pan Quanyi Wang Mingkun Li Jianbin Wang Yanyi Huang Jianwei Wang COVID-19 Field Response Group COVID-19 Laboratory Testing Group | 2020 | National Science Review2020，7，12： | 51 |
| 2 | Coal and gas outburst dynamic system显示文摘Coal and gas outburst is an extremely complex dynamic disaster in coal mine production process which will damage casualties and equipment facilities, and disorder the ventilation system by suddenly ejecting a great amount of coal and gas into roadway or working face. This paper analyzed the interaction among the three essential elements of coal and gas outburst dynamic system. A stress-seepage-damage coupling model was established which can be used to simulate the evolution of the dynamical system, and then the size scale of coal and gas outburst dynamical system was investigated. Results show that the dynamical system is consisted of three essential elements, coal-gas medium(material basis), geology dynamic environment(internal motivation) and mining disturbance(external motivation). On the case of C13 coal seam in Panyi Mine, the dynamical system exists in the range of 8–12 m in front of advancing face. The size scale will be larger where there are large geologic structures. This research plays an important guiding role for developing measures of coal and gas outburst prediction and prevention. | Fan Chaojun Li Sheng Luo Mingkun Du Wenzhang Yang Zhenhua | 2017 | International Journal of Mining Science and Technology2017，27，1： | 19 |
| 3 | Land cover change along the Qinghai-Tibet Highway and Railway from 1981 to 2001显示文摘Based on the NOAA AVHRR-NDVI monthly data from 1981 to 2001, the spatial distribution and dynamic change of land cover along the Qinghai-Tibet Highway and Railway were studied. The results of the analytical data indicate that the NDVI values in July, August and September are rather high during a year, and a linear trend by calculating NDVI of each pixel computed based on the average values of NDVI in July, August and September were obtained. The results are as follows: 1) Land cover of the study area by NDVI displays high at two sides of the area and low in the center, and agriculture area > alpine meadow > alpine grassland > desert grassland. 2) In the study area, the amount of pixels with high increase, slight increase, no change, slight decrease and high decrease account for 0.29%, 14.86%, 67.61%, 16.7% and 0.57% of the whole area, respectively. The increase of land cover pixels is mainly in the agriculture and alpine meadow and the decrease pixels mainly in the alpine grassland, desert grassland and hungriness. Grassland and hungriness contribute to the decrease mostly and artificial land and meadow contribute to the increase mostly. 3) In the area where human beings live, the changing trend is obvious, such as the valleys of Lhasa River and Huangshui River and area along the Yellow River; in the high altitude area with fewer people living, the changing trend is relatively low, like the area of Hoh Xil. 4) Human being’s behaviors are a key factor followed by the climate changes affecting land cover. | DING Mingkun ZHANG Yili SHEN Zhenx LIU Linshan ZHANG Wei WANG Zhaofeng BAI Wanqi ZHENG Du | 2006 | Journal of Geographical Sciences2006，16，4： | 15 |
| 4 | Genome Annotation of a Model Diatom Phaeodactylum tricornutum Using an Integrated Proteogenomic Pipeline显示文摘 | Mingkun Yang Xiaohuang Lin Xin Liu Jia Zhang Feng Ge | 2018 | Molecular Plant2018，11，10： | 5 |
| 5 | Soya saponin improves egg-laying performance and immune function of laying hens显示文摘Background:Soya saponin(SS),an active compound in soybean meals,has been widely studied in the medical field.However,it was considered as an anti-nutritional factor in poultry diets.The objective of this experiment was to measure the effects of dietary SS using three dietary treatments on egg-laying performance and immune function of laying hens.Birds were fed a low soybean meal basal diet(CON),a low-SS diet(50 SS)containing 50mg/kg SS,or a high-SS diet(500 SS)containing 500 mg/kg SS for 10 weeks.At the end of the 5th and 10th week of the trial,samples were collected for analysis.Results:Results showed that with 50 mg/kg SS supplementation,the egg production rate,feed conversion ratio(FCR),and eggshell quality tended to be improved.Serum follicle stimulating hormone(FSH)and Interleukin-4(IL-4)levels were also elevated as well as the peripheral blood LPS stimulation index,the proportion of B lymphocytes,and antibody titer of bovine serum albumin(BSA).We also found that mRNA levels of follicle stimulating hormone receptor(FSHR)in ovarian,nuclear transcription factor kappa B(NF-κB),Transforming growth factor(TGF-β)and interferonγ(IFN-γ)in spleen were up-regulated at the end of the trial.Additionally,dietary 50 mg/kg SS improved the ileal flora via up-regulating the relative abundance of Lactobacillus,Romboutsia and Lactobacillus delbrueckii.Although the immune related indicators were improved with 500 mg/kg SS supplemented,it seemed to have a negative influence on the laying-performance.Specifically,serum alanine aminotransferase(ALT),alkaline phosphatase(ALP),and the ratio of IFN-γto IL-4 were increased in the 500 SS group at the end of the trial.The m RNA levels of gonadotropin releasing hormone 1(GnRH1)in Hypothalamus,the estrogen related receptor(ERR)in ovaries were downregulated as well as the egg production rate during the trial with 500 mg/kg SS supplemented.Conclusions:The egg production performance was improved by dietary supplemented with 50 mg/kg SS via increasing ovarian FSHR transcription level and serum estrogen level.A beneficial shift in intestinal microflora was recorded,and the immune function of laying hens was also improved with 50 mg/kg SS supplementation.Surprisingly,the long-term supplementation of 500 mg/kg SS exerted a negative impact on the laying performance and physiological functions of the liver of laying hens. | Peng Li Yizhu Zhao Shaojia Yan Bocheng Song Yongfa Liu Mingkun Gao Dazhi Tang Yuming Guo | 2022 | Journal of Animal Science and Biotechnology2022，13，3： | 5 |
| 6 | Investigation and Green Prevention and Control Strategies of Pseudostellaria heterophylla Diseases in Genuine Producing Area in Zherong County显示文摘Zherong County of Fujian Province is a genuine producing area of Pseudostellaria heterophylla,and disease has become a main factor restricting the healthy development of P.heterophylla industry in the county.In order to scientifically understand the occurrence status of agricultural diseases and serve the GAP of P.heterophylla,P.heterophylla diseases in Zherong County were investigated,and the information and regularity of diseases were summarized.P.heterophylla diseases in Zherong County were infectious,and caused by fungi and viruses.The diseases occurred frequently in spring and summer,and symptoms were manifested in pathological changes of leaf and tuber.Eventually,green prevention and control strategies of diseases were put forward:cultivating new disease-resistant varieties,scientifically administrating drugs according to symptoms,administrating drugs in optimum period,strengthening biological control,strictly requiring drug safety period and paying attention to green prevention and control during the planting process.The occurrence of P.heterophylla diseases in Zherong County was investigated and summarized,and the corresponding strategies were put forward,so as to scientifically serve the agricultural industry in P.heterophylla genuine producing area,and to provide a basis for the sustainable development of modern pollution-free planting industry of P.heterophylla. | Chen Aqin Xu Qimian Jiang Huirong Gu Li Lin Congfa Jiang Yuanbin Lin Wei Xu Mingkun | 2020 | Plant Diseases and Pests2020，11，5： | 4 |
| 7 | Structure and deformation measurements of shallow overburden during top coal caving longwall mining显示文摘Mining induced pressures are strong and overburden failure areas are large in top coal caving longwall mining, which constrains high production and safety mining. By employing the combination of the full view borehole photography technique and the seismic CT scanner technique, the deformation and failure of overlying strata of fully mechanized caving face in shallow coal seam were studied and the failure development of overburden was determined. Results show that the full view borehole photography can reveal the characteristics of strata, and the seismic CT scanner can reflect the characteristics of strata between the boreholes. The combined measurement technique can effectively determine the height of fractured and caved zones. The top end of the caved zone in Yangwangou coal mine employing the top coal caving longwall mining was at the depth of 171 m and fractured zone was at the depth of 106-110 m. The results provide a theoretic foundation for controlling the overburden strata in the shallow buried top coal caving panel. | Li Sheng Fan Chaojun Luo Mingkun Yang Zhenhua Lan Tianwei Zhang Haifeng | 2017 | International Journal of Mining Science and Technology2017，27，6： | 4 |
| 8 | Q-switched fiber laser based on saturable absorption of ferroferric-oxide nanoparticles显示文摘We demonstrate that ferroferric-oxide(Fe_3O_4) nanoparticles exhibit nonlinear saturable absorption property at1.55 μm, and fabricate two filmy saturable absorbers by embedding the nanoparticles into a polyvinyl alcohol(PVA) film or polyimide(PI) film separately. In the Fe_3O_4-PVA(Fe_3O_4-PI) Q-switched fiber laser, the pulse repetition rate increases from 8.5 kHz(5.5 kHz) to 28 kHz(49 kHz) and the pulse duration decreases from 23.5 μs(47 μs) to 6 μs(3.5 μs) by varying the pump power from 25 m W(23 mW) to 150 m W(650 mW). Experiment results indicate that PI-based saturable absorbers can afford larger powers than PVA-based saturable absorbers, which can be attributed to the higher fusion point of the PI film. The Fe_3O_4-PI saturable absorber exhibits features of high damage threshold, low cost, and good flexibility, which could be applied in fields of near-infrared pulse generation and frequency conversions. | Dong Mao Xiaoqi Cui Wending Zhang Mingkun Li Tianxian Feng Bobo Du Hua Lu Jianlin Zhao | 2017 | Photonics Research2017，5，1： | 3 |
| 9 | Tensile properties analysis of CFRP-titanium plate multi-bolt hybrid joints显示文摘Hybrid joints have better tensile properties than pure bonded and bolted bolts,and are increasingly used in the aerospace field.Tensile tests are carried out for the Hybrid Bonded/Bolted(HBB)joints of Carbon Fiber Reinforced Polymer(CFRP)laminate and titanium alloy plate under different bolt numbers,and the corresponding load–displacement curves are obtained.At the same time,based on Continuum Damage Mechanics(CDM)theory,which is derived from 3D Hashin failure criteria,and a Cohesive Zone Model(CZM),the tensile strength prediction model of the composite laminate-titanium alloy plate multi-bolted HBB joint was established,and the numerical simulation results were in good agreement with the experimental height,which validate the feasibility of the model.The difference in the bearing capacity of HBB joints under different numbers of bolts is compared and analyzed.On this basis,the influence of inter-bolt distance on the tensile properties of the HBB joints is explored.The results show that the double-nail HBB joints can effectively improve the end warpage and low bearing capacity of the single-nail HBB joints.The tensile failure load of the double-nail HBB joints under the standard lap width(30 mm)is 82.6%higher than that of the single nail,the tensile failure load of the three-bolt HBB joints is 34.1%higher than that of the double nail.For the three-bolt HBB joint,the joint strength is controlled by the adhesive and the external bolt,while the internal bolt is redundant,the hybrid joint can be simplified by reducing the middle bolt.The inter-bolt distance has a great influence on the failure load of the hybrid joint.Increasing the inter-bolt distance can effectively improve the bearing capacity of the structure. | Yanping ZHENG Chaoyu ZHANG Ying TIE Xu WANG Mingkun LI | 2022 | Chinese Journal of Aeronautics2022，35，3： | 2 |
| 10 | Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice显示文摘Dear Editor,Hypercholesterolemia is the leading risk factor for cardiovascular diseases.Current evidence suggests that the heritability for blood cholesterol levels is high,with 40%-60%in different cohorts.1,2 Genome-wide association study(GWAS)is a powerful tool to ascertain the contribution of common genetic variants in population-wide disease variability.It has been performed extensively on blood lipids traits and hundreds of genome variants are associated with dyslipidemia.However,approximately 95%of these variants are located in genome noncoding regions and cluster in more than 300 loci in different populations. | Fangfang Han Xiao Liu Chuanfang Chen Yinan Liu Mingkun Du Yu Zhou Yong Liu Bao-Liang Song Housheng Hansen He Yan Wang | 2020 | Cell Research2020，30，4： | 2 |
| 11 | Genomes of major fishes in world fisheries and aquaculture: Status, application and perspective显示文摘Capture fisheries and aquaculture provide a significant amount of high-quality protein to human beings and thus play an essential role in ending global hunger and malnutrition.The availability of tens of hundreds of fish genomes and the advances of genomics have allowed addressing many challenging issues such as overfishing and germplasm degradation faced by fisheries and aquaculture.In this review,we describe the current status of genomics in fisheries and aquaculture,with an emphasis on 14 species of fish that are considerably important to global fisheries and aquaculture,in the context of genome sequencing and assembly,annotation,GC contents,and repeats.The majority of these genomes are assembled at the chromosome level and annotated with proteins and pathways,with functional relevance to fisheries and aquaculture,such as environmental adaptation and phenotypic variation.We summarize potential genomic applications in fisheries and aquaculture that are related to assessment and use of genetic resources,disease resistance,growth and development,sexual determination,and fisheries management.Although much progress has been achieved in genomic application to fisheries and aquaculture,the full potential remains to be explored and reaped.We discuss the challenges and perspectives of genomics in translational aquaculture and fisheries,which include genome assembly and annotation,genomic selection and breeding,genomics in fisheries management,and integrated artificial intelligence systems.In the coming decades,we anticipate the applications of genomic techniques such as genome editing and genomic selection,along with the use of emerging intelligence systems,in aquaculture and fisheries will contribute significantly to genetic improvements of farmed fish and sustainable exploitation of fishery resources,which consequently lead to eradicating global poverty by 2030,an ambitious goal set by the United Nations. | Guoqing Lu Mingkun Luo | 2020 | Aquaculture and Fisheries2020，5，4： | 2 |
| 12 | A WO3 nanorod-Cr2O3 nanoparticle composite for selective gas sensing of 2-butanone显示文摘The hexagonal(h)-WO_3-Cr_2 O_3 nanocomposites with different W/Cr molar ratio of 4:1.10:1 and 40:1 were prepared by a facile two-step hydrothermal method, and its gas sensing properties were investigated under optimum working temperature. X-ray diffraction(XRD), scanning electron microscopy(SEM).transmission electron microscopy(TEM), high resolution transmission electron microscopy(HRTEM)were used to characterize the morphology, microstructure and crystallinity of the as-synthesized samples. The hexagonal W03 nanorods show a better crystallinity than Cr_2 O_3 nanoparticles. When the molar ratio of W/Cr is 10:1, the hexagonal WO_3-Cr_2 O_3 nanocomposite shows obvious selectivity toward2-butanone at 205℃ compared with other typical reducing gases, and the response value to 100 ppm 2-butanone can reach 5.6. However, there is no selectivity toward 2-butanone when the Cr/W molar ratio is1:4 and 1:40. Furthermore, hexagonal W03-Cr2 O3 nanocomposites have a short response and recovery time to 5 ppm 2-butanone, which is 10 s and 80 s, respectively. The measured results indicate that hexagonal WO_3-Cr_2 O_3 nanocomposite is a potential gas sensing material for monitoring volatile organic compounds(VOCs). | Qian Zhang He Zhang Mingkun Xu Zhurui Shen Qiang Wei | 2018 | Chinese Chemical Letters2018，29，3： | 2 |
| 13 | Preparation and characterization of quaternized chitosan/ poly(acrylontrile) composite nanofiltration membrane from anhydride mixture cross-linking显示文摘 | Ruihua Huang Guohua Chen Mingkun Sun | 2008 | Sep Purif Technol2008，58，3： | 1 |
| 14 | Microstructure,magnetic domain and dynamic loss of surface-textured Fe-based nanocrystalline alloy显示文摘Heterogeneous coarse surface crystallites induced in the industrial Fe-rich nanocrystalline alloy is an obstacle for high-frequency and high-power commercial applications.Herein,the phase,crystal orientation,nanostructure and magnetic domain evolution of the surface-crystallized Fe-rich alloy were systematically investigated.Microstructure and inverse pole figures analysis confirms that the DOordered dendriticcrystallites bear<001>-oriented fiber texture before and after annealing at the free surface,while ultrafine nanocrystals are randomly oriented in the interior and wheel surface after annealing.As compared to zero magnetic-field-annealing,the transverse magnetic-field-annealing induces weakly oriented fiber texture and relatively uniform dendritic-crystallites at the surface,and uniform anisotropy in the interior and surface,which promotes smooth wall motion at the surface and magnetization rotation in the interior.This synergetic effect reduces the excess loss and leads reduction in dynamic loss at 1.0 T and10 kHz by 36%. | Aina He Jiawei Li Mingkun Wang Anding Wang Yao Xiao Yaqiang Dong Hai Guo Rongrong Jiang Weixing Xia Lihong Dong Haidou Wang Jianya Ge | 2022 | Journal of Materials Science & Technology2022，，25： | 1 |
| 15 | Population Genetics of SARS-CoV-2: Disentangling Effects of Sampling Bias and Infection Clusters显示文摘A novel RNA virus,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is responsible for the ongoing outbreak of coronavirus disease 2019(COVID-19).Population genetic analysis could be useful for investigating the origin and evolutionary dynamics of COVID-19.However,due to extensive sampling bias and existence of infection clusters during the epidemic spread,direct applications of existing approaches can lead to biased parameter estimations and data misinterpretation.In this study,we first present robust estimator for the time to the most recent common ancestor(TMRCA)and the mutation rate,and then apply the approach to analyze 12,909 genomic sequences of SARS-CoV-2.The mutation rate is inferred to be 8.69×10^(−4) per site per year with a 95%confidence interval(CI)of[8.61×10^(−4),8.77×10^(−4)],and the TMRCA of the samples inferred to be Nov 28,2019 with a 95%CI of[Oct 20,2019,Dec 9,2019].The results indicate that COVID-19 might originate earlier than and outside of Wuhan Seafood Market.We further demonstrate that genetic polymorphism patterns,including the enrichment of specific haplotypes and the temporal allele frequency trajectories generated from infection clusters,are similar to those caused by evolutionary forces such as natural selection.Our results show that population genetic methods need to be developed to efficiently detangle the effects of sampling bias and infection clusters to gain insights into the evolutionary mechanism of SARS-CoV-2.Software for implementing VirusMuT can be downloaded at http://gffzzdbc7b6aaae734bddsffqwk9ub59ob6wcb.ffgz.tsg.suse.edu.cn/biocode/tools/BT007081. | Qi Liu Shilei Zhao Cheng-Min Shi Shuhui Song Sihui Zhu Yankai Su Wenming Zhao Mingkun Li Yiming Bao Yongbiao Xue Hua Chen | 2020 | Genomics, Proteomics & Bioinformatics2020，18，6： | 1 |
| 16 | Parameter identification of interconnected power system frequency after trip-out of high voltage transmission line显示文摘精确建模和格子是的高电压(HV ) 的参数为系统频率的稳定性研究批评。在这篇论文,模拟当模特儿系统频率与传播在中国衬里的 HV 一个互连的力量系统被进行。基于使 HV 传播线的数据犯错记录,系统参数被使用基因算法(GA ) 识别。在模拟结果和记录数据之间的有利协议验证有效性系结模型和系统参数的精确性。这篇论文的结果能为 HV 力量格子的稳定性研究提供参考。 | Xuzhan ZHOU Yaohua TANG Shanshan LIU Mingkun WANG Yiping DAI | 2014 | Frontiers in Energy2014，8，3： | 1 |
| 17 | Design of Software to Search ASP Web Shell显示文摘 | Xu Mingkun Chen Xi Hu Yan | | 0，，： | 1 |
| 18 | Tracking control of a 3-DOF rehabilitation robot actuated by pneumatic muscle actuators using adaptive self-organising fuzzy sliding mode control显示文摘 | Chang Mingkun Lin Shouyee Yuan Tsanhsiu | 2011 | International Journal of Intelligent Systems Technologies and Applications2011，10，1： | 1 |
| 19 | Confidence-Based Active Learning 显示文摘 | LI Mingkun SETHI I K | 2006 | IEEE Transactions on Pattern Analysis and Machine Intelligence2006，28，8： | 1 |
| 20 | Processing of highly concentrated polyacrylamide-coated silicon carbide suspensions显示文摘 | Mingkun Wei Guangjun Qide Wu | 2004 | Ceramics International2004，30，： | 1 |
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