|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinical effects of innovative tuina manipulations on treating cervical spondylosis of vertebral artery type and changes in cerebral blood flow显示文摘OBJECTIVE:To determine the clinical effect,treatment times,and rheoencephalogram changes in vertebral artery type cervical spondylosis patients treated with innovative Tuina manipulations.METHODS:One hundred and twenty six cervical spondylosis patients(vertebral artery type) were randomly divided into test and control groups.Patients in the test group were treated with innovative Tuina manipulations,while those in the control group were treated with the routine Tuina manipulations according to the textbook of Chinese Massage for Acupuncture and Moxibustion majors.The clinical effects,treatment times,clinical symptoms,and cerebral blood flow were measured.RESULTS:The response to the treatment was 100% in the test group and 88.71% in the control group.Patients in the test group required(7 ± 4) treatments before recovery,while those in the control group required(15 ± 7) treatments before recovery(P<0.05).The clinical symptoms exhibited greater improvement in the test group compared to the control group(P<0.05).There were no differences in cerebral blood flow between the two groups.CONCLUSION:Both innovative Tuina manipulations and routine Tuina manipulations produced satisfactory therapeutic results in vertebral artery type cervical spondylosis patients.However,the innovative manipulation was more effective in improving the functional symptoms,although there were no changes in the cerebral blood flow. | Quanmao Ding Mingru Yan Ji Zhou Lu Yang Jiang Guo Jun Wang Zhiyong Shi Yixi Wang Hongsheng Zhao | 2012 | Journal of Traditional Chinese Medicine2012，32，3： | 24 |
| 2 | BOUNDARY AND CORNER LAYER BEHAVIOR IN SINGULARLY PERTURBED ROBIN BOUNDARY VALUE PROBLEM显示文摘This paper is concerned with boundary and corner layer behavior of the singularly perturbed Robin boundary value problem(RP) for the second-order nonlinear differential equations. The existence and asymptotic estimate of solutions of (RP) is discussed by appropriately constructing the bounding functions and using the theory of differential inequality. | Zhou Mingru | 2005 | Annals of Differential Equations2005，21，4： | 8 |
| 3 | Study on fish life history traits and variation in the Taiwan Strait and its adjacent waters显示文摘Large portions of the world's fishery resources are overexploited. Life history traits of fish species are important indicators to reveal different life history strategies and to indicate population responses to fishing pressures. For this study, empirical data on fishing grounds located in the coastal area between Fujian Coast and Taiwan Island were collected. These areas have experienced severe overfishing in the past 30 years, leading to changes in the structure and function of the fish communities. Fifty-one commercial fish species in this fishing ground were selected to study the life history traits. Using the life history traits, all the species were grouped into five different life history strategies by principle component analysis. More than 60% of the species were categorized in Group 5 that was similar to r-strategists. Twenty-five commercial species were selected for further analysis of changes in life history variables, and to discuss the population responses to exploitation. Results showed that most of the species appeared to become smaller size, shorter life, earlier maturation and faster growing under long-term exploitation. The exploitation rate of each species was also calculated to further discuss the impacts of fishing pressures to fish populations. Four species were found with the severest changes on life history traits indicating some of the species might be more susceptible to exploitation. This study on fish life history traits and their long-term variations under fishing pressures could provide important scientific implications for fishery management and conservation. | HU Wenjia YE Guanqiong LU Zhenbin DU Jianguo CHEN Mingru CHOU Loke Ming YANG Shengyun | 2015 | Acta Oceanologica Sinica2015，34，2： | 3 |
| 4 | The effects of different nitrogen sources on camptothecin content and related gene expression in Camptotheca acuminata seedlings显示文摘Camptotheac acuminata Decne is a unique tree species in China with an important secondary metabolite,camptothecin(CPT),used in the treatment of cancer.Nitrogen(N)is an important element that affects plant growth and the accumulation of CPT.Reports on the effect of N on CPT synthesis from a genetic perspective are scarce.To explore the effects of different N sources and levels on CPT synthesis in C.acuminata,two-year-old seedlings were fertilized with different concentrations of pure ammonium sulphate,source of ammonium N(NH4+-N),and potassium nitrate for nitrate N(NO3--N).Concentrations of 2.5,5,7.5,and10 g pot-1 NH4+-N and NO3--N were used.The results showed that 7.5 g NH4+-N and NO3--N treatments were best for growth and fresh weight of leaves.Compared with the other treatments,the CPT content,tryptophan synthase and tryptophan decarboxylase activities,and expression of the CaTSB and CaTDCl genes under the 2.5 g NH4+-N and NO3--N treatments peaked significantly at 30 days.However,the expression of CaTDC2 surpassed that of the other two genes at 60 days.Therefore,compared with NH4+-N source,the NO3--N source was more beneficial for growth,and NO3--N was better for CPT yield.Consequently,leaves of C.acuminata treated with 2.5 g NO3--N could be harvested after 30 days to obtain maximum CPT content.CaTDC1 is more closely linked to CPT synthesis.The results of this study improved the production of CPT in C.acuminata via fertilization. | Xiaode Wang Sainan Bian Pengjie Chang Ninghang Wang Lingjuan Xuan Mingru Zhang Bin Dong Chao Zhang Jiasheng Wu Yeqing Ying Xiazhen Lin Yamei Shen | 2020 | Journal of Forestry Research2020，31，4： | 3 |
| 5 | Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial显示文摘Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication.Meplazumab is a humanized anti-CD147 IgG_(2) monoclonal antibody,which may effectively prevent SARS-CoV-2 infection in coronavirus disease 2019(COVID-19)patients.Here,we conducted a randomized,double-blinded,placebo-controlled phase 1 trial to evaluate the safety,tolerability,and pharmacokinetics of meplazumab in healthy subjects,and an open-labeled,concurrent controlled add-on exploratory phase 2 study to determine the efficacy in COVID-19 patients.In phase 1 study,59 subjects were enrolled and assigned to eight cohorts,and no serious treatment-emergent adverse event(TEAE)or TEAE grade≥3 was observed.The serum and peripheral blood Cmax and area under the curve showed non-linear pharmacokinetic characteristics.No obvious relation between the incidence or titer of positive anti-drug antibody and dosage was observed in each cohort.The biodistribution study indicated that meplazumab reached lung tissue and maintained>14 days stable with the lung tissue/cardiac blood-pool ratio ranging from 0.41 to 0.32.In the exploratory phase 2 study,17 COVID-19 patients were enrolled,and 11 hospitalized patients were involved as concurrent control.The meplazumab treatment significantly improved the discharged(P=0.005)and case severity(P=0.021),and reduced the time to virus negative(P=0.045)in comparison to the control group.These results show a sound safety and tolerance of meplazumab in healthy volunteers and suggest that meplazumab could accelerate the recovery of patients from COVID-19 pneumonia with a favorable safety profile. | Huijie Bian Zhao-Hui Zheng Ding Wei Aidong Wen Zheng Zhang Jian-Qi Lian Wen-Zhen Kang Chun-Qiu Hao Jing Wang Rong-Hua Xie Ke Dong Jie-Lai Xia Jin-Lin Miao Wen Kang Guoquan Li Di Zhang Mingru Zhang Xiu-Xuan Sun Likun Ding Kui Zhang Junfeng Jia Jin Ding Zhiqin Li Yanyan Jia Lin-Na Liu Zhe Zhang Zhao-Wei Gao Hong Du Na Yao Qing Wang Ke Wang Jie-Jie Geng Bin Wang Ting Guo Ruo Chen Yu-Meng Zhu Li-Juan Wang Qian He Rui-Rui Yao Ying Shi Xiang-Min Yang Jian-Sheng Zhou Yi-Nan Ma Ya-Tao Wang Xue Liang Fei Huo Zhe Wang Yang Zhang Xu Yang Ye Zhang Lu-Hua Gao Ling Wang Xiao-Chun Chen Hao Tang Shuang-Shuang Liu Qing-Yi Wang Zhi-Nan Chen Ping Zhu | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 6 | Pore Structure Characteristics of Baking-Free Slag-Sludge Bricks and Its Correlations to Mechanical Properties显示文摘In order to explore the relationship between the macroscopic properties and pore structure characteristics of baking-free slag-sludge bricks,the compressive strength and water absorption rate using aluminum industrial slag and sludge of different substitution rates were tested.Optical instruments and image analysis software were used to measure the parameters of the pore structure.Specifically,a fractal model was built based on the fractal theory,in which the fractal dimension was used as the characteristic index of the pore structure to analyze the correlation and interaction mechanism between the fractal dimension and the macroscopic mechanical properties.Based on this study,conclusions were drawn as follows:(1)The plane pore structure of baking-free bricks shows good fractal characteristics.With the increase of the aluminum industrial slag content,the fractal dimension becomes smaller and the pore structure develops well;with the increase of the sludge content,the fractal dimension becomes larger and the pore structure becomes worse;(2)As the fractal dimension of the plane pore structure increases,the compressive strength of baking-free bricks falls,and the porosity and water absorption rise;(3)The optimum content of baking-free slag-sludge bricks is aluminum industrial slag 30%and sludge 10%.After 7 days of curing,baking-free bricks boast higher performance,and fully meet the performance requirements of solid concrete bricks(MU40),which can reduce time costs,and enhance enterprise revenue. | Lei Guo Pingping Chen Lixia Guo Zhilong Xue Zi Guan Mingru Li | 2021 | Journal of Renewable Materials2021，9，10： | 2 |
| 7 | Microstructure and mechanical properties of railway wheels manufactured with low-medium carbon Si-Mn-Mo-V steel显示文摘The suitability of carbide-free bainite steel as railway wheel materials was investigated. The low-medium carbon Si-Mn-Mo-V steel was designed to make railway wheels by forging and rolling. The slack quenching with water was conducted on the tread of rim section by programmed control to simulate isothermal heat treatment after being austenitized. Microstructures and mechanical properties have been studied. The results indicate that the microstructure of the rim is mainly carbide-free bainite, and the mixed microstructure of bainitic ferrite and granular bainite is observed in web and hub. The mechanical properties are superior to both the standard requirements and the commercial production, such as CL60 plain carbon. The Charpy impact energy is relatively high at room and/or subzero temperatures. The force-displacement curves and fractographies reveal the excellent ability of resistance to crack initiation and propagation. | Mingru Zhang Haicheng Gu | 2008 | Journal of University of Science and Technology Beijing2008，15，2： | 2 |
| 8 | Hyers-Ulam stability of linear differential equations of first order 显示文摘 | Wang Guangwa Zhou Mingru Sun Li | 2008 | Appl Math Lett2008，21，： | 1 |
| 9 | A facile synthesis of graphite/silicon/graphene spherical composite anode for lithium-ion batteries显示文摘 | Lei Gan Huajun Guo Zhixing Wang Xinhai Li Wenjie Peng Jiexi Wang Silin Huang Mingru Su | 2013 | Electrochimica Acta2013，，： | 1 |
| 10 | Effect of carbides on wear characterization of high-alloy steels under high-stress rolling-sliding condition 显示文摘 | Xu Liujie Wei Shizbong Han Mingru | 2014 | Tribology Transactions2014，57，4： | 1 |
| 11 | Singularly perturbations for third-order nonlinear multi-point boundary value prob- lem显示文摘 | Du Zengji Ge Weigao Zhou Mingru | 2005 | J Differential Equations2005，218，1： | 1 |
| 12 | Effects of Recycled Aggregate Content on Pervious Concrete Performance显示文摘A recycled aggregate(RA)was prepared by crushing and sieving demolished discarded concrete pavements and was subsequently tested and analyzed to determine its various physical properties.On this basis,pervious concrete(PC)mix proportions were designed.Coarse RA particles with sizes of 5–10 and 10–20 mm were selected.Concrete specimens were prepared with a water–cement ratio of 0.3,an aggregate–cement ratio of 4.5,the substitute rates of RA with 0,25%,50%,75%and a single-/double-gap-graded RA mix(mass ratio of particles with sizes of 5–10 mm to particles with sizes of 10–20 mm:1:1,1:2,2:1,2:3 and 3:2).Various properties of the RA-containing PC(RPC)were determined by analyzing the compressive strength,splitting tensile strength,effective porosity,permeation coefficient and impact and abrasion resistance of the specimens.The results showed the following:The density of the RPC decreased with an increasing RA replacement ratio.The density of the RPC prepared with a double-gapgraded RA mix was lower than that prepared with a single-gap-graded RA(particle size:10–20 mm)mix.The permeation coefficient of the RPC increased with increasing porosity.The splitting tensile strength of the RPC was positively correlated with its compressive strength.The compressive strength of the RPC decreased with increasing porosity.The regression analysis showed that the impact and abrasion resistance of the RPC increased with increasing compressive strength.In addition,all of the RPC specimens met the strength and permeation requirements.This study can provide theoretical support for the application of RPC. | Lei Guo Zi Guan Lixia Guo Weiping Shen Zhilong Xue Pingping Chen Mingru Li | 2020 | Journal of Renewable Materials2020，8，12： | 1 |
| 13 | A flocculation dosing control of water treatment process based on real-time expert system显示文摘 | Zeng Mingru Chen Xiang Sun Dazhi | 2005 | Journal of Nanchang University: Engineering & Technology2005，27，3： | 1 |
| 14 | Effect of 'Pt' loading in ZnO-CuO hetero-junction material sensing carbon monoxide at room temperature显示文摘 | Yu Mingru Wu Renjang Chavali M | 2011 | Sensors and Actuators B : Chemical2011，153，2： | 1 |
| 15 | Silicon, flake graphite and phenolic resin-pyrolyzed carbon based Si/C composites as anode material for lithium-ion batteries显示文摘 | Su Mingru Wang Zhixing Guo H uaj un | 2013 | Adv Powder Technol2013，24，： | 1 |
| 16 | Existence of solutions of boundary value problems for the system of third order nonlinear differential equations显示文摘 | Zhou Mingru Du Zengji | | 应用数学与力学(待发)0，，： | 1 |
| 17 | Age and growth changes and population dynamics of the black pomfret (Parastro- mateus niger) and the frigate tuna (Auxis thazard thazard), in the Taiwan Strait显示文摘 | YU Tao CHEN Mingru DU Jianguo | 2012 | Lat Am J Aquat Res2012，40，3： | 1 |
| 18 | Me- chanical behavior and microstructural variation of loess under dynamic compaction 显示文摘 | Hua Ruilin Yeung Mingru Lee Zhoufen | 2001 | Engineering Geology2001，59，34： | 1 |
| 19 | Singular perturbations for third-order nonlinear multi- point boundary value problem显示文摘 | Du Zengji Ge Weigao Zhou Mingru | 2005 | J Differ Equa2005，218，1： | 1 |
| 20 | Studies on ecological characteristics variation and population dynamics of four lizardfishes in the southern Taiwan Straits显示文摘The ecological characteristics of four lizardfishes, Trachinocephalus myops, Saurida undosquamis, Saurida tumbil and Saurida elongata, were studied from specimens (910 T. myops, 454 S. un-dosquamis, 686 S. tumbil and 744 S. elongata) collected monthly in the southern Taiwan Straits from April 2005 to March 2006. The population dynamics of the four lizardfishes was also discussed by the comparison with the previous studies. All being composed of 7 a classes; the dominant group of T. myops and S. tumbil was 1-2 a, while S. undosquamis and S. elongate were 2-3 a. The total mortality coefficient Z and the fishing mortality F were at high as indicated by the exploitation ratio E(>0.5), and a large number of by-caught juvenile and young fishes showing that the stock of lizardfishes in this area was overexploited and the fishing gear was irrational. Compared with the previous studies, the maximum and mean fork length, body mass and age of the four lizard- fishes declined gradually, the lizardfishes populations were younger in age and smaller in size. The asymptotic fork length L ∞ decreased while increasing growth coefficient k, and age at the inflexion point of mass t r was younger compared with the previous studies. The declining of older ones has moderated the feeding competition and the younger ones grew faster. The larger mortality param-eters Z, M and F have revealed higher fishing pressure. The smaller change of the first mature fork length of female T . myops and the change from K selection pattern to r selection pattern of S. tumbil have indicated a more vulnerable fishery ecosystem in this area. The changes of ecological characteristics and population dynamics may be caused by over-exploitation of demersal fishes such as the lizardfishes, especially a large number of juvenile and young fishes by-catch by the current fishing gears and methods. Therefore, in addition to the traditional fishery management approach such as the minimum length-limit, ecosystem approach to fisheries management (EAF) should be taken to improve the practical marine ecosystem management, including increased fishing intensity of the non-economic species especially the feeding competitors of the lizardfishes and the conservation of the pelagic fishery population in the fisheries ecosystem, in order to restore the fishery population and achieve the sustainable use of the fishery stocks. | DU Jianguo LU Zhenbin YANG Shengyun CHEN Mingru | 2011 | Acta Oceanologica Sinica2011，30，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员