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| 1 | A simple strain sensor using a thin film as a low-finesse fiber-optic Fabry-Perot interferometer显示文摘 | | 2001 | Sensors and Actuators2001,88,: | 1 |
| 2 | A PPM probabilistic packet marking improving scheme显示文摘 | JIANG Hua LI Mingzhen WANG Xin | 2011 | Journal of Shandong University:Natural Science2011,46,9: | 1 |
| 3 | Production performance analysis for composite shale gas reservoir considering multiple transport mechanisms显示文摘 | Xu Jianchun Guo Chaohua Wei Mingzhen Jiang Ruizhong | 2015 | Journal of Natural Gas Science and Engineering2015,26,: | 1 |
| 4 | Plant and animal positive-sense single-stranded RNA viruses encode small proteins important for viral infection in their negative-sense strand显示文摘Positive-sense single-stranded RNA(+ssRNA)viruses,the most abundant viruses of eukaryotes in nature,require the synthesis of negative-sense RNA(-RNA)using their genomic(positive-sense)RNA(+RNA)as a template for replication.Based on current evidence,viral proteins are translated via viral+RNAs,whereas-RNA is considered to be a viral replication intermediate without coding capacity.Here,we report that plant and animal+ssRNA viruses contain small open reading frames(ORFs)in their-RNA(reverse ORFs[rORFs]).Using turnip mosaic virus(TuMV)as a model for plant+ssRNA viruses,we demonstrate that small proteins encoded by rORFs display specific subcellularlocalizations,and confirm the presence of rORF2 in infected cells through mass spectrometry analysis.The protein encoded by TuMV rORF2 forms punctuate granules that are localized in the perinuclear region and co-localized with viral replication complexes.The rORF2 protein can directly interact with the viral RNA-dependent RNA polymerase,and mutation of rORF2 completely abolishes virus infection,whereas ectopic expression of rORF2 rescues the mutant virus.Furthermore,we show that several rORFs in the-RNA of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have the ability to suppress type l interferon production and facilitate the infection of ve-sicular stomatitis virus.In addition,we provide evidence that TuMV might utilize internal ribosome entry sites to translate these small rORFs.Taken together,these findings indicate that the-RNA of+ssRNA vi-ruses can also have the coding capacity and that small proteins encoded therein play critical roles in viral infection,revealing a viral proteome larger than previously thought. | Pan Gong Qingtang Shen Mingzhen Zhang Rui Qiao Jing Jiang Lili Su Siwen Zhao Shuai Fu Yu Ma Linhao Ge Yaqin Wang Rosa Lozano-Durán Aiming Wang Fangfang Li Xueping Zhou | 2023 | Molecular Plant2023,16,11: | 0 |
| 5 | Hot deformation behavior and the processing map of Zr–1.0Be alloy in single α phase显示文摘The hot deformation behavior,hot workability and dynamic recrystallization evolution of Zr-1.0(wt%) Be alloy in single a phase were investigated by conducting hot compression tests.The strain rates ranging from 10^(-3) s^(-1) to 10° s^(-1) and testing temperatures varying from 650 ℃to 850℃ were used.Flow stress was found to increase with increasing strain rate and decrease with the increment of the deformation temperature.A constitutive equation of flow behavior was established to describe the dependence of flow stress on strain rate and deformation temperature.The activation energy for deformation of Zr-1.0Be alloy was determined to be Q= 301 kJ/mol.The processing map of Zr-1.0Be alloy was constructed at strain rates ranging from 10^(-3) s^(-1) to 10° s^(-1) and deformation temperatures varying from 650 ℃ to 850 ℃ at the true strain of 0.7.A processing map was used to identify the best domains of thermal processing,including a domain at a temperature of 650 ℃ and strain rate of 10^(-3) s^(-1) as well as another domain at deformation temperatures ranging from 800 ℃ to 850 ℃ and strain rates varying from 10^(-3) s^-^(-1) to 10^(-1) s^(-1).Microscopic analysis of Zr-l.OBe alloy showed that the flow instability and kink were very obvious at low temperatures and high strain rates.At high temperatures and low strain rates,the dynamic recrystallization became the main softening mechanism during hot working. | Zhihao Feng Xiaojun Jiang Yunkai Zhou Chaoqun Xia Xinyu Zhang Mingzhen Ma Riping Liu | 2015 | Progress in Natural Science:Materials International2015,25,5: | 0 |
| 6 | Venetoclax and Azacitidine in Chinese patients with untreated acute myeloid leukemia ineligible for intensive chemotherapy显示文摘Dear Editor,Acute Myeloid Leukemia(AML)patients are often found ineligible for aggressive standard chemotherapy in clinic because of old age and poor conditions.Current evidences suggest that targeted combination therapy might help these patients achieve a higher response rate with acceptable adverse events(AEs).^(1)Venetoclax(VEN),a selective small-molecule BCL2 inhibitor,combined with hypomethylating agent(HMA),such as azacytidine(AZA). | Leiming Xia Wanlu Tian Yiming Zhao Lingling Jiang Wei Qian Lei Jiang Ling Ge Jianjun Li Fengbo Jin Mingzhen Yang | 2023 | Signal Transduction and Targeted Therapy2023,8,6: | 0 |
| 7 | Dynamic Response Analysis of Semi-Submersible Floating Wind Turbine with Different Wave Conditions显示文摘To address the problem of poor wave resistance of existing offshore floating wind turbines,a new type of semisubmersible platform with truncated-cone-type upper pontoons is proposed by combining the characteristics of offshore wind turbine semi-submersible floating platforms.Based on the coupled hydrodynamic,aerodynamic,and mooring force physical fields of FAST,the surge,heave,pitch,and yaw motions responses of the floating wind turbine under different wave heights and periods are obtained,and the mooring line tension responses are also obtained;and compare the dynamic response of the new semi-submersible platform with the OC4-DeepCwind platformat six degrees of freedom.The results show that different wave conditions have obvious effects on the heave and pitch motions of the new floating wind turbine,and fewer effects on the surge and yaw motions;the tensegrity response of the mooring system is more affected by the wave conditions;compared with the OC4-DeepCwind floating wind turbine,the pitch and roll response of the new floating wind turbine has been significantly reduced and has good stability. | Mingzhen Jiang Guanghui Qiao Jiwen Chen Xuemei Huang Leian Zhang Yongshuang Wen Yuhuan Zhang | 2023 | Energy Engineering2023,120,11: | 0 |
| 8 | Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2023 edition)显示文摘To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization,led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles,research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles,Professional Committee on Extracellular Vesicle Research and Application,Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles.Based on the collation of relevant literature,we have adopted the Delphi method,the consensus meeting method combined with the nominal group method to form a discussion draft of“Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2023)”.The first draft was discussed in online and offline meetings on October 12,14,November 2,2022 and April and May 2023 on the current status of research,nomenclature,isolation methods,quality standards and research applications of extracellular vesicles of Chinese herbal medicines,and 13 consensus opinions were finally formed.At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles,held on May 26,2023,Kewei Zhao,convenor of the consensus,presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles.The consensus highlights the characteristics and advantages of Chinese medicine,inherits the essence,and keeps the righteousness and innovation,aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad,decode the mystery behind Chinese herbal vesicles together,establish a safe,effective and controllable accurate Chinese herbal vesicle prevention and treatment system,and build a bridge for Chinese medicine to the world. | Qing Zhao Tong Wang Hongbin Wang Peng Cao Chengyu Jiang Hongzhi Qiao Lihua Peng Xingdong Lin Yunyao Jiang Honglei Jin Huantian Zhang Shengpeng Wang Yang Wang Ying Wang Xi Chen Junbing Fan Bo Li Geng Li Bifeng Liu Zhiyang Li Suhua Qi Mingzhen Zhang Jianjian Zheng Jiuyao Zhou Lei Zheng Kewei Zhao | 2024 | Chinese Herbal Medicines2024,16,1: | 0 |