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| 1 | Clinical significance of the leptin and leptin receptor expressions in prostate tissues显示文摘瞄准:在良性的专业版静电干扰增生(BPH ) 和前列腺癌症(PCa ) 计算 leptin 和 leptin 受体的表达式,并且调查他们是否与 PCa 的开发和前进被联系。方法:染色的 Immunohistochemical 被执行在 BPH 和 PCa 检验 leptin 和 leptin 受体的表示。PCa 被划分成三个组:局部性的 PCa,局部地先进的 PCa 和变形 PCa。积极染色被识别,积极染色的百分比被分级。我们也估计了在格利森分数和身体团索引(BMI ) 和 PCa 之间的关系。结果:在 PCa 的 leptin 表示的百分比在 BPH 比那显著地高(P <
0.01 ) 。为 PCa 组, leptin 的表示层次与局部性的 PCa 和变形 PCa 显示出可观的关联(P <
0.05 ) 。然而, Leptin 受体没揭示 BPH 和 PCa 之间的明确的差别。leptin 的表示显示了区分得好的 PCa 之间的重要差别(格利森 20 ≤
6 ) 并且糟糕区分的 PCa (格利森分数 8 10 )(P <
0.05 ) 。在在 PCa 和 BMI 的 leptin 表示水平之间的关系不是显著的(P= 0.447 ) 。结论:我们的结果建议 leptin 可能在 PCa 的 carcinogenesis 和前进上有支持的效果。 | Jung Hoon Kim Shin Young Lee Soon Chul Myung Young Sun Kim Tae-Hyoung Kim Mi Kyung Kim | 2008 | Asian Journal of Andrology2008，10，6： | 6 |
| 2 | Clinical correlations of infliximab trough levels and antibodies to infliximab in South Korean patients with Crohn's disease显示文摘AIM To investigate the clinical implications of infliximab trough levels(IFX-TLs) and antibodies to infliximab(ATI) levels in Crohn's disease(CD) patients in Asian countries. METHODS IFX-TL and ATI level were measured using prospectively collected samples obtained with informed consent from CD patients being treated at Asan Medical Center, South Korea. We analyzed the correlations between IFX-TLs/ATI levels and the clinical activity of CD(quiescent vs active disease) based on the CD activity index, C-reactive protein level, and physician's judgment of patients' clinical status at enrollment. The impact of concomitant immunomodulators was also investigated. RESULTS This study enrolled 138 patients with CD(84 with quiescent and 54 with active disease). In patients with quiescent and active diseases, the median IFX-TLs were 1.423 μg/mL and 0.163 μg/mL, respectively(P < 0.001) and the median ATI levels were 8.064 AU/m L and 11.209 AU/m L, respectively(P < 0.001). In the ATI-negative and-positive groups, the median IFXTLs were 1.415 μg/mL and 0.141 μg/mL, respectively(P < 0.001). In patients with and without concomitant immunomodulator use, there were no differences in IFX-TLs(0.632 μg/mL and 1.150 μg/mL, respectively; P = 0.274) or ATI levels(8.655 AU/mL and 9.017 AU/mL, respectively; P = 0.083).CONCLUSION IFX-TL/ATI levels were well correlated with the clinical activity in South Korean CD patients. Our findings support the usefulness of IFX-TLs/ATI levels in treating CD patients receiving IFX in clinical practice. | Eun Hye Oh Dae-Hyun Ko Hyungil Seo Kiju Chang Gwang-Un Kim Eun Mi Song Myeongsook Seo Ho-Su Lee Sung Wook Hwang Dong-Hoon Yang Byong Duk Ye Jeong-Sik Byeon Seung-Jae Myung Suk-Kyun Yang Sang Hyoung Park | 2017 | World Journal of Gastroenterology2017，23，8： | 2 |
| 3 | Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease显示文摘 | Jung Mi Choi Myoung Soo Woo Hyeo-Il Ma Suk Yun Kang Young-Hee Sung Seok Woo Yong Sun Ju Chung Joong-Seok Kim Hae-won Shin Chul Hyoung Lyoo Phil Hyu Lee Jong Sam Baik Sang-Jin Kim Mee Young Park Young Ho Sohn Jin-Ho Kim Jae Woo Kim Myung Sik Lee Myoung Cho | 2008 | Neurogenetics2008，，4： | 1 |
| 4 | Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors显示文摘 | Eun Mi Je Nam Jin Yoo Yoo Jin Kim Myung Shin Kim Sug Hyung Lee | 2013 | Int J Cancer2013，，1： | 1 |
| 5 | Benefit of Early Statin Therapy in Patients With Acute Myocardial Infarction Who Have Extremely Low Low-Density Lipoprotein Cholesterol显示文摘 | Ki Hong Lee Myung Ho Jeong Ha Mi Kim Youngkeun Ahn Jong Hyun Kim Shung Chull Chae Young Jo Kim Seung Ho Hur In Whan Seong Taek Jong Hong Dong Hoon Choi Myeong Chan Cho Chong Jin Kim Ki Bae Seung Wook Sung Chung Yang Soo Jang Seung Woon Rha Jang Ho Bae Jeo | 2011 | Journal of the American College of Cardiology2011，，16： | 1 |
| 6 | Response of high-sensitivity C-reactive protein to percutaneous coronary intervention in patients with acute coronary syndrome显示文摘 | Kyeong Ho Yun Myung Ho Jeong Seok Kyu Oh Sang Jae Rhee Eun Mi Park Eun Mi Lee Nam Jin Yoo Nam-Ho Kim Young Keun Ahn Jin-Won Jeong | 2009 | Heart and Vessels2009，，3： | 1 |
| 7 | The beneficial effect of high loading dose of rosuvastatin before percutaneous coronary intervention in patients with acute coronary syndrome显示文摘 | Kyeong Ho Yun Myung Ho Jeong Seok Kyu Oh Sang Jae Rhee Eun Mi Park Eun Mi Lee Nam Jin Yoo Nam-Ho Kim Young Keun Ahn Jin-Won Jeong | 2008 | International Journal of Cardiology2008，，3： | 1 |
| 8 | Angiotensin Ⅱ Receptor Blocker Attenuates Overexpression of Vascular Endothelial Growth Factor in Diabetic Podocytes显示文摘 | EUN-YOUNG LEE MYUNG SOOK SHIM MI JIN KIM | 2004 | Experimental and Moleculan Medicine2004，36，1： | 1 |
| 9 | Comparison of excyclotorsion following graded inferior oblique recession for primary versus secondary inferior oblique overaction显示文摘AIM:To compare the changes in excyclotorsion after inferior oblique(IO)recession in patients with primary and secondary inferior oblique overaction(IOOA).METHODS:We retrospectively analyzed the data obtained from patients with IOOA who underwent graded IO recession.The patients were followed up for at least 3 mo after surgery.Fundus photographs were taken preand postoperatively,and the sum of the angles of torsion in both eyes was used to analyze changes in excyclotorsion.Patients were divided into two groups:those diagnosed with primary IOOA were enrolled in the 1’IOOA group,and those diagnosed with secondary IOOA caused by superior oblique palsy(SOP)were enrolled in the 2’IOOA group.Excyclotorsion before and after surgery were compared between the two groups.RESULTS:A total of 78 patients were enrolled in this study:34 eyes in the 1’IOOA group and 44 eyes in the 2’IOOA group.In the 78 patients,torsional angle significantly decreased from 15.31°±7.40°to 12.11°±6.53°after IO recession(P<0.001).Mean preoperative torsional angle was larger in the 2’IOOA group than in the 1’IOOA group(P=0.03).In both groups,excyclotorsion significantly decreased after IO recession(P=0.001 and P<0.001,respectively);however,there was no significant difference in the amounts of changes in excyclotorsion between the two groups.CONCLUSION:Excyclotorsion is significantly larger in secondary IOOA than in primary IOOA,and a significant decrease in the torsional angle occurs after IO recession in both types of IOOA. | Donghun Lee Won Jae Kim Myung Mi Kim | 2020 | International Journal of Ophthalmology(English edition)2020，13，8： | 1 |
| 10 | 6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation显示文摘 | Gunhyuk Park Hyo Geun Kim Mi Sun Ju Sang Keun Ha Yongkon Park Sun Yeou Kim Myung Sook Oh | 2013 | Acta Pharmacologica Sinica2013，34，9： | 1 |
| 11 | A Novel Small Molecule Facilitates the Reprogramming of Human Somatic Cells into a Pluripotent State and Supports the Maintenance of an Undifferentiated State of Human Pluripotent Stem Cells显示文摘 | Jungwoon Lee Yan Xia Mi‐Young Son Guanghai Jin Binna Seol Min‐Jeong Kim Myung Jin Son Misol Do Minho Lee Dongsup Kim Kyeong Lee Yee Sook Cho | 2012 | Angew Chem Int Ed2012，，50： | 1 |
| 12 | Response of high-sensitivity C-reactive protein to percutaneous coronary intervention in patients with acute coronary syndrome显示文摘 | Kyeong Ho Yun Myung Ho Jeong Seok Kyu Oh Sang Jae Rhee Eun Mi Park Eun Mi Lee Nam Jin Yoo Nam-Ho Kim Young Keun Ahn Jin-Won Jeong | 2009 | Heart and Vessels2009，，3： | 1 |
| 13 | Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells显示文摘 | Sokbom Kang Seung Myung Dong Boh-Ram Kim Mi Sun Park Barry Trink Hyun-Jung Byun Seung Bae Rho | 2012 | Apoptosis2012，，9： | 1 |
| 14 | A Ds-insertion mutant of OSH6 (Oryza sativa Homeobox 6) exhibits outgrowth of vestigial leaf-like structures, bracts, in rice显示文摘 | Sung Han Park Chul Min Kim Byoung Il Je Su Hyun Park Soon Ju Park Hai Long Piao Yuan-hu Xuan Mi Sook Choe Kouji Satoh Shoshi Kikuchi Kon Ho Lee Young Soon Cha Byung Ohg Ahn Hyeon So Ji Doh Won Yun Myung Chul Lee Seok-cheol Suh Moo Young Eun Chang-deok Han | 2007 | Planta2007，，1： | 1 |
| 15 | Selection of F2 genotype resistant to soybean cyst nematode using molecularmarkers显示文摘 | Won Gyeong Park Myung Sik Kim Mi Suk Ko | 2003 | Korean Journal of Breeding2003，35，： | 1 |
| 16 | Anthocyanins from black soybean inhibit Helicobacter pylori ‐induced inflammation in human gastric epithelial AGS cells显示文摘 | Jung‐Min Kim Kyung‐Mi Kim En‐Hee Park Ji‐Hyun Seo Jae‐Young Song Sung‐Chul Shin Hyung‐Lyun Kang Woo‐Kon Lee Myung‐Je Cho Kwang‐Ho Rhee Hee‐Shang Youn Seung‐Chul Baik | 2013 | Microbiol Immunol2013，，5： | 1 |
| 17 | Relationship of thyroid stimulating hormone with coronary atherosclerosis in angina patients显示文摘 | Kyeong Ho Yun Myung Ho Jeong Seok Kyu Oh Eun Mi Lee Je Lee Sang Jae Rhee Nam Jin Yoo Nam-Ho Kim Young Keun Ahn Jin-Won Jeong | 2006 | International Journal of Cardiology2006，，1： | 1 |
| 18 | Luminescence characteristics of green light emitting Ba2SiO4:Eu2+ phosphor显示文摘 | Mi Ae Lim Joung Kyu Park Chang Hae Kim Hee Dong Park Myung Wan Han | 2003 | Journal of Materials Science Letters2003，，19： | 1 |
| 19 | Analysis of PTEN Gene Mutations in Korean Patients With Cowden Syndrome and Polyposis Syndrome显示文摘 | Dae-Kyoum Kim M.D. Seung-Jae Myung M.D. Suk-Kyun Yang M.D. Seong Soo Hong M.D. Kyu Jong Kim M.D. Jeong-Sik Byeon M.D. Gin Hyug Lee M.D. Jin-Ho Kim M.D. Young Il Min M.D. Sun Mi Lee B.S. Jin-Yong Jeong Ph.D. Kyuyoung Song Ph.D. Sung-Ae Jung M.D | 2005 | Diseases of the Colon & Rectum2005，，9： | 1 |
| 20 | Modulation of lipid metabolism by polyphenol‐rich grape skin extract improves liver steatosis and adiposity in high fat fed mice显示文摘 | Hae‐Jin Park Un Ju Jung Mi‐Kyung Lee Su‐Jung Cho Hee‐Kyoung Jung Joo Heon Hong Yong Bok Park Sang Ryong Kim Sangphil Shim Jieun Jung Myung‐Sook Choi | 2012 | Mol. Nutr. Food Res2012，，2： | 1 |
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