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| 1 | Gd-EOB-DTPA-enhanced magnetic resonance imaging features of hepatic hemangioma compared with enhanced computed tomography显示文摘AIM:To clarify features of hepatic hemangiomas on gadolinium-ethoxybenzyl-diethylenetriaminpentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) compared with enhanced computed tomography (CT). METHODS:Twenty-six patients with 61 hepatic hem- angiomas who underwent both Gd-EOB-DTPA-enhanced MRI and enhanced CT were retrospectively reviewed. Hemangioma appearances (presence of peripheral nodular enhancement, central nodular enhancement, diffuse homogenous enhancement, and arterioportal shunt during the arterial phase, fill-in enhancement during the portal venous phase, and prolonged enhancement during the equilibrium phase) on Gd-EOB-DTPA-enhanced MRI and enhanced CT were evaluated.The degree of contrast enhancement at the enhancing portion within the hemangioma was visually assessed using a five-point scale during each phase. For quantitative analysis, the tumor-muscle signal intensity ratio (SIR), the liver-muscle SIR, and the attenuation value of the tumor and liver parenchyma were calculated. The McNemar test and the Wilcoxon's signed rank test were used to assess the significance of differences in the appearances of hemangiomas and in the visual grade of tumor contrast enhancement between Gd-EOB-DTPA-enhanced MRI and enhanced CT. RESULTS:There was no significant difference between Gd-EOB-DTPA-enhanced MRI and enhanced CT in the presence of peripheral nodular enhancement (85% vs 82%), central nodular enhancement (3% vs 3%), diffuse enhancement (11% vs 16%), or arterioportal shunt (23% vs 34%) during arterial phase, or fill-in enhancement (79% vs 80%) during portal venous phase. Prolonged enhancement during equilibrium phase was observed less frequently on Gd-EOB-DTPA-enhanced MRI than on enhanced CT (52% vs 100%, P < 0.001). On visual inspection, there was significantly less contrast enhancement of the enhancing portion on Gd-EOB-DTPA-enhanced MRI than on enhanced CT during the arterial (3.94 ± 0.98 vs 4.57 ± 0.64, respectively, P < 0.001), portal venous (3.72 ± 0.82 vs 4.36 ± 0.53, respectively, P < 0.001), and equilibrium phases (2.01 ± 0.95 vs 4.04 ± 0.51, respectively, P < 0.001). In the quantitative analysis, the tumor-muscle SIR and the liver-muscle SIR observed with Gd-EOB-DTPA-enhanced MRI were 0.80 ± 0.24 and 1.28 ± 0.33 precontrast, 1.92 ± 0.58 and 1.57 ± 0.55 during the arterial phase, 1.87 ± 0.44 and 1.73 ± 0.39 during the portal venous phase, 1.63 ± 0.41 and 1.78 ± 0.39 during the equilibrium phase, and 1.10 ± 0.43 and 1.92 ± 0.50 during the hepatobiliary phase, respectively. The attenuation values in the tumor and liver parenchyma observed with enhanced CT were 40.60 ± 8.78 and 53.78 ± 7.37 precontrast, 172.66 ± 73.89 and 92.76 ± 17.92 during the arterial phase, 152.76 ± 35.73 and 120.12 ± 18.02 during the portal venous phase, and 108.74 ± 18.70 and 89.04 ± 7.25 during the equilibrium phase, respectively. Hemangiomas demonstrated peak enhancement during the arterial phase, and both the SIR with Gd-EOB-DTPA-enhanced MRI and the attenuation value with enhanced CT decreased with time. The SIR of hemangiomas was lower than that of liver parenchyma during the equilibrium and hepatobiliary phases on Gd-EOB-DTPA-enhanced MRI. However, the attenuation of hemangiomas after contrast injection was higher than that of liver parenchyma during all phases of enhanced CT. CONCLUSION:Prolonged enhancement during the equilibrium phase was observed less frequently on Gd-EOB-DTPA-enhanced MRI than enhanced CT, which may exacerbate differentiating between hemangiomas and malignant tumors. | Akihiro Tateyama Yoshihiko Fukukura Koji Takumi Toshikazu Shindo Yuichi Kumagae Kiyohisa Kamimura Masayuki Nakajo | 2012 | World Journal of Gastroenterology2012，18，43： | 19 |
| 2 | Clinical Significance of Lymph Node Micrometastasis in Gastric Cancer显示文摘 | Takaaki Arigami Yoshikazu Uenosono Shigehiro Yanagita Akihiro Nakajo Sumiya Ishigami Hiroshi Okumura Yuko Kijima Shinichi Ueno Shoji Natsugoe | 2013 | Annals of Surgical Oncology2013，，2： | 3 |
| 3 | A phase II study of oral S-1 with concurrent radiotherapy followed by chemotherapy with S-1 alone for locally advanced pancreatic cancer显示文摘 | Hiroyuki Shinchi Kosei Maemura Yuko Mataki Hiroshi Kurahara Masahiko Sakoda Shinichi Ueno Yoshiyuki Hiraki Masayuki Nakajo Shoji Natsugoe Sonshin Takao | 2012 | Journal of Hepato - Biliary - Pancreatic Sciences2012，，2： | 2 |
| 4 | Oncoplastic Surgery for Japanese Patients with Centrally Located Breast Cancer: Partial Resection and Reconstruction Using a Local Skin-Glandular Flap显示文摘 | Yuko Kijima Heiji Yoshinaka Munetsugu Hirata Tadao Mizoguchi Sumiya Ishigami Akihiro Nakajo Hideo Arima Youta Kawasaki Shinichi Ueno Shoji Natsugoe | 2011 | Journal of US-China Medical Science2011，8，3： | 2 |
| 5 | Decomposition of dichloromethane in a wire-in-tube pulsed corona reactor 显示文摘 | HUANG L W NAKAJO K OZAWA S | 2001 | Environmental Science & Technology2001，35，6： | 1 |
| 6 | The RRASK motif in xenopus cyclin B2 is required for the substrate recognition of Cdc25C by the cyclin B-Cdc2 complex 显示文摘 | Goda T Ishii T Nakajo N | 2003 | J Biol Chem2003，278，19： | 1 |
| 7 | Iodine-123 Iodobenzofuran(I-123 IBF) SPECT in patients with parkinsonism显示文摘 | Nakabeppu O Nakajo M Mitsuda M | 1999 | Ann Nucl Med1999，13，6： | 1 |
| 8 | Endocrine cell carcinoma (carcinoid) of the gallbladder显示文摘 | Yamamoto M Nakajo S Miyoshi N | 1989 | Am J Surg Pathol1989，13，4： | 1 |
| 9 | Strong convergence theorems for nonexpansive mappings and nonexpansive semigroups 显示文摘 | Nakajo K Takahashi W | 2003 | J Math Anal Appl2003，279，： | 1 |
| 10 | Infiltration of antitumor immunocytes into the sentinel node in gastric cancer显示文摘 | Sumiya Ishigami M.D. Shoji Natsugoe M.D. Yoshikazu Uenosono M.D. Yoichi Hata M.D. Aikihiro Nakajo M.D. Futoshi Miyazono M.D. Masataka Matsumoto M.D. Shuichi Hokita M.D. Takashi Aikou M.D | 2003 | Journal of Gastrointestinal Surgery2003，，6： | 1 |
| 11 | Prognostic value of CCR7 expression in gastric cancer显示文摘 | Ishigami S Natsugoe S Nakajo A | 2007 | Hepatogastroen- terology2007，54，76： | 1 |
| 12 | Strong convergence theorems for nonexpansive mappings and nonexpansive semigroups显示文摘 | NAKAJO K TAKAHASHI W | 2003 | J Math Anal Appl2003，279，： | 1 |
| 13 | A rare case of idiopathic retroperitoneal fibrosis involving obstruction of themesenteric arteries, duodenum, common bile duct, and inferior vena cava显示文摘 | Tamura S Yokoyama Y Nakajo K | 2003 | Intern Med2003，42，9： | 1 |
| 14 | Protein kinase C shifts the voltage dependence of KCNQ/M channels expressed in Xenopus oocytes显示文摘 | Nakajo K Kubo Y | 2005 | J Physiol2005，569，： | 1 |
| 15 | Embolization of spontaneous rupture of an aneurysm of the ovarian artery supplying the uterus with fibroids显示文摘 | Nakajo M Ohkubo K Fukukura Y | 2005 | Aeta Radiol2005，46，： | 1 |
| 16 | Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson!s disease and dementia with Lewy bodies显示文摘 | Baba M Nakajo S Tu P H | 1998 | Am J Pathol1998，152，4： | 1 |
| 17 | Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson′s disease and dementia with Lewy bodies显示文摘 | BABA M NAKAJO S TU P H | | 0，，04： | 1 |
| 18 | Evaluation of endoscopic mucosal resection for laterally spreading rectal tumors 显示文摘 | Tamura S Nakajo K Yokoyarna Y | 2004 | Endoscopy2004，36，4： | 1 |
| 19 | Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells显示文摘 | Masuda Y Kawazoe N Nakajo S | 1995 | Leuk Res1995，19，8： | 1 |
| 20 | Bone marrow micrometastasis detected by RT-PCR in esophageal squamous cell carcinoma显示文摘 | NATSUGOE S NAKASHIMA S NAKAJO A | 2003 | Oncol Rep2003，10，6： | 1 |
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