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| 1 | 在有症状的患者中,与传统危险因素相比,冠状动脉钙化积分能更准确地预测显著的冠状动脉狭窄:欧洲钙化性冠状动脉疾病研究显示文摘在这项回顾性研究中,研究人员评估了冠状动脉钙化积分相对于传统危险因素对显著狭窄(冠状动脉狭窄〉50%)的预测价值。方法与结果:纳入来自丹麦、法国、德国、意大利、西班牙和美国有症状的患者5515例,所有研究对象均进行危险因素评估、计算机断层冠状动脉造影(computed tomographic coronary angiogram,CTCA)或常规血管造影。 | 刘莉 叶鹏 Nicoll R Wiklund U Zhao Y Diederichsen A Mickley H Ovrehus K Zamorano P Gueret P Schmermund A Maffei E Cademartiri F Budoff M Henein M | 2016 | 中华高血压杂志2016，24，3： | 4 |
| 2 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 3 | Increased metallothionein gene expression,zinc,and zinc-dependent resistance to apoptosis in circulating monocytes during HIV viremia显示文摘 | Raymond A D Gekonge B Giri M S Hancock A Papasavvas E Chehimi J Kossenkov A V Nicols C YousefM Mounzer K Shull J Kostman J Showe L Montaner L J | | 0，，03： | 1 |
| 4 | 查看详情显示文摘 | C A Walker T G F Gray A C Nicol E K J Chadwick | | 0，，： | 1 |
| 5 | Phthalic acid diamides activate ryanodine-sensitive Ca2+ release channels in insects显示文摘 | ULRICH E K PETER L NICOLE L | | 0，，： | 1 |
| 6 | FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles显示文摘The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies.Over the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats.Yet,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging.In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels.Combining the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,respectively.This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental stud-ies.In order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences.On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2020 | Fungal Diversity2020，，6： | 1 |
| 7 | Biodegradation of aliphatic and aromatic hydrocar-bons: specificity among bacteria isolated from refinerywaste sludge显示文摘 | KATSIVELA E EDWARD R B NICOLS K | 2003 | Water Air and Soil Pollution2003，3，： | 1 |
| 8 | Seasonality Research: The State of the Art 显示文摘 | Nicole K L Eberhard E B | 2005 | International Journal of Tourism Research2005，7，45： | 1 |
| 9 | Optimal investment decisions when time-horizon is uncertain显示文摘 | Christophette B S Nicole E K Monique J | 2008 | Journal of Mathematical Economics2008，44，： | 1 |
| 10 | Synthesis and physicochemical analysis of gelatin-based hydrogels for drug carrier matrices 显示文摘 | NICOLE J E KELLY R S WEIYUAN J K | 2003 | Biomaterials2003，24，3： | 1 |
| 11 | Antimicrobial treatment in diabetic women with asymptomatic bacteriuria显示文摘 | Zhanel G G Nicolle L E | 2002 | N Engl J Med2002，347，20： | 1 |
| 12 | Nondestructive measurement of fruit and vegetable quality by means of NIR spectroscopy :A review 显示文摘 | Nicolal B M Beullens K Bobelyn E | 2007 | Postharvest Biology and Technolo- gy2007，46，2： | 1 |
| 13 | Optimal investment decisions when time-horizon is uncertain 显示文摘 | CHRISTOPHETTE B S NICOLE E K MONIQUE J | 2008 | Journal of Mathematical Economics2008，44，11： | 1 |
| 14 | Resection of complex pancreatic injuries: Benchmarking postoperative complications using the Accordion classification显示文摘AIM To benchmark severity of complications using the Accordion Severity Grading System(ASGS) in patients undergoing operation for severe pancreatic injuries. METHODS A prospective institutional database of 461 patients with pancreatic injuries treated from 1990 to 2015 was reviewed. One hundred and thirty patients with AAST grade 3, 4 or 5 pancreatic injuries underwent resection(pancreatoduodenectomy, n = 20, distal pancreatectomy, n = 110), including 30 who had an initial damage controllaparotomy(DCL) and later definitive surgery. AAST injury grades, type of pancreatic resection, need for DCL and incidence and ASGS severity of complications were assessed. Uni-and multivariate logistic regression analysis was applied. RESULTS Overall 238 complications occurred in 95(73%) patients of which 73% were ASGS grades 3-6. Nineteen patients(14.6%) died. Patients more likely to have complications after pancreatic resection were older, had a revised trauma score(RTS) < 7.8, were shocked on admission, had grade 5 injuries of the head and neck of the pancreas with associated vascular and duodenal injuries, required a DCL, received a larger blood transfusion, had a pancreatoduodenectomy(PD) and repeat laparotomies. Applying univariate logistic regression analysis, mechanism of injury, RTS < 7.8, shock on admission, DCL, increasing AAST grade and type of pancreatic resection were significant variables for complications. Multivariate logistic regression analysis however showed that only age and type of pancreatic resection(PD) were significant. CONCLUSION This ASGS-based study benchmarked postoperative morbidity after pancreatic resection for trauma. The detailed outcome analysis provided may serve as a reference for future institutional comparisons. | Jake E Krige Eduard Jonas Sandie R Thomson Urda K Kotze Mashiko Setshedi Pradeep H Navsaria Andrew J Nicol | 2017 | World Journal of Gastrointestinal Surgery2017，9，3： | 1 |
| 15 | Anaerobic digestates are useful nutrient sources for microalgae cultivation:Functional coupling of energy and biomass production显示文摘 | Biornsson W J Nicol R W Dickinson K E | 2013 | J Appl Phycol2013，25，5： | 1 |
| 16 | Constrained optimization with respect to stochastic dominance: Application to portfolio insurance 显示文摘 | Nicole E K Asma M | 2006 | Mathematical Finance2006，16，1： | 1 |
| 17 | Wheat genetic resources enhancement by the international maize and wheat improvement center (cimmyt)显示文摘 | Ortiz R Braun H J Crossa J Crouch J Davenport G Dixon J Dreisigacker S Duveiller E He Z Huerta J Joshi A Kishii M Kosina P Manes Y Mezzalama M Morgounov A Murakami J Nicol J Ortiz Ferrara G Ortiz-Monasterio J Payne T Pe A R Reynolds M Sayre K Sharma R Singh R Wang J Warburton M Wu H Iwanaga M | 2008 | Genetic Resources and Crop Evolution2008，55，7： | 1 |
| 18 | Nanostructured composite materials with improved deformation behavior显示文摘 | JURGEN E UTA K JAYANTA D SERGIO S NICOLLE R | 2005 | Advanced Engineering Materials2005，7，7： | 1 |
| 19 | 人内皮反转录病毒K上调与肺动脉高压免疫和炎症相关显示文摘免疫失调与遗传性、特发性和其他情况导致的肺动脉高压(pulmonary arterial hypertension,PAH)中的闭塞性血管重塑有关。循环自身免疫抗体,肺部血管周围淋巴组织以及细胞因子升高都与PAH的病理机制有关,但是这些异常是怎样产生、维持并与疾病的发展联系在一起的仍不明确。为了了解这些问题,研究者将鉴别PAH中肺部特殊的免疫复合物的特异性靶抗原作为出发点,来更好地为未来的免疫调节治疗的应用提供基础。 | 黄洁 叶鹏 Saito T Miyagawa K Chen SY Tamosiuniene R Wang L Sharp O Samayoa E Harada D Moonen JAJ Cao A Chen PI Hennigs JK Gu M Li CG Leib RD Li D Adams CM Del Rosario PA Bill MA Haddad F Montoya JG Robinson W Fantl WJ Nolan GP Zamanian RT Nicolls MR Chiu CY Ariza ME Rabinovitch M | 2017 | 中华高血压杂志2017，25，10： | 0 |
| 20 | Correction to:FungalTraits:a user friendly traits database of fungi and fungus-like stramenopiles显示文摘Correction to:Fungal Diversity(2020)105:116 http://gffzzd3cc09b8251d45dfsnnnuf9ockpkn6b55.ffgz.tsg.suse.edu.cn/10.1007/s13225-020-00466-2 There were errors in the name of author LászlóG.Nagy and in affiliation no.31 in the original publication.The original article has been corrected. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks LászlóIrinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew P.Nelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2021 | Fungal Diversity2021，，2： | 0 |
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