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| 1 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017,9,14: | 2 |
| 2 | Comparison of gastric vas cular anatomy by monochromatic and polychromatic dual-energy spectral computed tomography imaging显示文摘 | Yamin Wan Zhizhen Li Nina i | 2014 | J International Medi cal Research2014,42,1: | 1 |
| 3 | Comparative study of the pollen wall development in Illicium floridanum (Illiciaeeae) and Schisandra chinensis (Schisandraeeae)显示文摘 | NINA I G VALENITNA V G | 2003 | Taiwania2003,48,3: | 1 |
| 4 | Near-Infrared Fluorescence Imaging as an Alternative to Bioluminescent Bacteria to Monitor Biomaterial-Associated Infections显示文摘 | Nina Dinjaski Suri Shalu Jaione Valle Susan M. Lehman I?igo Lasa María Auxiliadora Prieto Andrés J. García | 2014 | Acta Biomaterialia2014,,: | 1 |
| 5 | Observations on the experimental destruction and substructural organisation of the pollen wall of some selected Gymnosperms and Angiosperms显示文摘 | NINA I G STEPHEN B JOHN R R | 2003 | Review of Palaeobotany and Palynology2003,124,: | 1 |
| 6 | Determination of residual ractopamine concentrations by enzyme immu- noassay in treated pig tissues on days after withdrawal显示文摘 | Jelka PIeadin Nina Per i Ana Vuli | 2012 | Meat Science2012,122,3: | 1 |
| 7 | Transition along gradient from warm to mesic temperate forests evaluated by GAMM显示文摘Aims The aim of the study was to discover what set of variables best explains the transition from warm to mesic forest vegetation.Based on various variables grouped into sets(geomorphological,ecological,structural,soil characteristics and chorological),six models were built and tested by generalized additive mixed models(GAMMs).We assumed that each set of variables has different explanatory power.Our aim was to compare the six different models(sets of variables),to test which model best explains the species turnover in forest communities along the transition between warm and mesic temperate forests and to try to find reasons for the different explanatory power of the models.Methods The research took place in the southern part of the Balkan Peninsula.Field sampling was done according to standard methods.The gradient from warm to mesic forests was defined as the turnover of species and evaluated by projection of samples on the first unconstrained DCA axis.Geomorphological,ecological,structural and soil characteristics,together with chorological sets of variables,were regressed on the turnover of species composition.Based on the five sets of variables,six models were constructed and tested by generalized additive mixed models.Important Findings Ecological conditions best explain the change of forest communities along the gradient;evolution and the development of vegetation reflected in chorotypes are also of high importance;geomorphology and structure seem not to change so dramatically and soil shows the least significant differences of all.Ecological variables are the most important set of variables in the transition between warm and mesic temperate forests but eco-evolutionary dynamics after the Pleistocene should also be taken into consideration. | AndražČarni Vlado Matevski Nina Juvan Mitko Kostadinovski Petra Košir Aleksander Marinšek Andrej Paušič UrbanŠilc | 2016 | Journal of Plant Ecology2016,9,4: | 1 |
| 8 | Layer-by-Layer Assembly of Ultrathin Composite Films from Micron-Sized Graphite Oxide Sheets and Polyeations 显示文摘 | Nina I Kovtyukhova Patricia J Ollivier Benjamin R Martin | 1999 | Chem Mater1999,11,77: | 1 |
| 9 | ACEI of Trichoderma reesei is a repressor of cellulase and xylanase expression显示文摘 | Nina A Marja I Anu S | 2003 | Applied and Environmental Microbiology2003,69,1: | 1 |
| 10 | Biolumlnescence-based bioassays for rapid detection of nisin in food 显示文摘 | NINA I MATTI K | 2007 | Biosensors and Bioelectronics2007,22,: | 1 |
| 11 | Transforming growth factor beta I (TGF beta I) gone expression by eosinophils in asthmatic airway inflammation 显示文摘 | Ohno I Nina Y Yamauchi K | 1996 | Am J Respir Cell Mol Biol1996,15,: | 1 |
| 12 | Detection of DNA damage in haemocytes of zebra mussel using comet assay 显示文摘 | Mirjana Pavlica Goran I V Klobu Nina Moja | 2001 | Mutation Res/Genetic Toxicol Environment Mutagenesis2001,490,2: | 1 |
| 13 | Association of Genetic polymorphisms in the organic cation transporters Octl, Oct2 and multidrug and toxin extrusion 1 transporter protein with the metformin intolerance and weight lowering in patients of type 2 diabetes显示文摘 | Tarasova L Klovins J nina I | 2011 | Endocrine Abstracts2011,,: | 1 |
| 14 | Detection of DNA damage in baemocytes of zebra mussel using comet assay 显示文摘 | Mirjana Pavliea G Ran I V Klobu Nina Moja ctal | 2001 | Mutation Research/Genetic Toxicology and Environ- mental Mutagenesis2001,490,2: | 1 |
| 15 | Detection of DNA damage in gametocytes of zebra mussel using comet assay 显示文摘 | Mirjana Pavlica Gran I V Klobu Nina Moja | 2001 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis2001,490,2: | 1 |
| 16 | Cervical cancer diagnosed shortly after pregnancy: prognostic valiables and delivery routes显示文摘 | Sood Anil K Sorosky Joel I Mayr Nina | 2000 | Obstet Gynecol2000,95,: | 1 |
| 17 | Detection of DNA dam- age in haemocy tes of zebra mussel using comet assay 显示文摘 | Mirjana P Goran I V K Nina M | 2001 | Murat Res2001,490,2: | 1 |
| 18 | ACEI of Trichoderma reesei is a repressor of cellulase and xylanase expression显示文摘 | NINA A MARJA I ANu S | 2003 | Applied and Environmental Microbiology2003,69,1: | 1 |
| 19 | Determination of residual ractopamine concentrations by enzyme immunoassay in treated pig’s tissues on days after withdrawal显示文摘 | Jelka Pleadin Nina Per?i Ana Vuli? Dinka Mili? Nada Vah?i? | 2011 | Meat Science2011,,3: | 1 |
| 20 | Layer-by-layer assembly of ultrathin composite films from micron-sized graphite oxide sheets and polycations 显示文摘 | NINA I K PATRICIA J O BENJAMIN R M el al | 1999 | Chem Mater1999,11,: | 1 |