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| 1 | A review of cable layout design and assembly simulation in virtual environments显示文摘The layout and assembly of flexible cables play important roles in the design and development of complex electromechanical products.The rationality of cable layout design and the reliability of cable assembly greatly affect product quality.In this paper,we review the methods of cable layout design,cable assembly process planning,and cable assembly simulation.We first review research on flexible cable layout design(both interactive and automatic).Then,research on the cable assembly process planning,including cable assembly path and manipulation planning,is reviewed.Finally,cable assembly simulation is introduced,which includes general cable information,cable collision detection data,and cable assembly process modeling.Current problems and future research directions are summarized at the end of the paper. | Xiaodong YANG Jianhua LIU Naijing LV Huanxiong XIA | 2019 | Virtual Reality & Intelligent Hardware2019，1，6： | 2 |
| 2 | Arsenic,Iron and Organic Matter in Quaternary Aquifer Sediments from Western Hetao Basin,Inner Mongolia显示文摘To investigate geochemical and mineralogical features of sediments from aquifers containing high levels of dissolved arsenic(As) in western Hetao Basin, Inner Mongolia, sediment samples were collected for XRD(X-ray diffraction), amorphous Fe/Mn oxides, and humic/fulvic acid analyses, in addition to As determination. In the study area, the total As contents in the sediments were in the range 5.3–28.8 mg/kg; while that associated with humic substances in the range 4–9 mg/kg, accounting for 26%–47% of the total As. The results of XRD analysis suggest that clay and silt contain certain small amounts of iron oxides minerals, such as ferrihydrite, hematite and goethite, whereas have higher As and Fe_2O_3 contents. Up to one third of As in the sediments could be extracted by ammonium oxalate, and high As contents were generally found in organic-rich clay or silty clay samples with high FA/HA ratio. As is strongly associated with humic substances and Fe oxyhydroxides, which may be the major sink and source of As in the aquifer sediments. | Naijing Liu Yamin Deng Ya Wu | 2017 | Journal of Earth Science2017，28，3： | 1 |
| 3 | Emergence of trend trading and its effects in minority game显示文摘 | Liu Xinghua Liang Xiaobei Wang Naijing | 2006 | Physca A2006，369，： | 1 |
| 4 | Emergence of Trend Trading and Its Effects In Minority Game显示文摘 | Liu Xinghua Xiaobei Liang Naijing Wang | 2006 | Physica A2006，，： | 1 |
| 5 | High-Affinity Decoy PD-1 Mutant Screened from an Epitope-Specific Cell Library显示文摘Immunotherapy with anti-programmed cell death protein-1(PD-1)/programmed cell death ligand-1(PDL1)monoclonal antibodies has become routine in the treatment of many kinds of human cancers,such as lung cancer,intestinal cancer,and melanoma.The PD-1/PD-L1 pathway inhibits T cell activation in the micro-environment,making it an attractive target against cancer.Wild-type(WT)PD-1 ectodomain has been shown to have difficulty blocking PD-1/PD-L1 mixture formation due to its low affinity.The present work uses three-dimensional(3D)crystal complex structures to analyze the interaction by which PD-1 binds to PD-L1 or PD-L2.It also reports on a theoretical study of the binding mode between PD-1 and its clinical antibody Opdivo.Based on the theoretical binding analysis of PD-1 and its ligands(i.e.,PD-L1 and PD-L2)or antibody(Opdivo),a small-content,epitope-oriented mammalian cell library was established for PD-1.After three rounds of cell sorting,the decoy PD-1 mutant 463,which presented a higher affinity than WT PD-1 to the PD-L1(the affinity has increased by almost three orders of magnitude)was screened out.It exhibited an inhibitory effect against PD-1 to prevent it from forming mixtures with PD-L1,which was similar to the effect of the commercial anti-PD-L1 antibody atezolizumab(ATE).The median effective concentration(EC50)value of the decoy mutant was 0.031 μg·mL^(-1) in comparison with 0.063 μg·mL^(-1) for ATE;both values were much lower than that of WT PD-1,at 2.571 μg·mL^(-1).The 463 decoy mutant reversed the inhibitory function of PD-1 in T cell activation;furthermore,10 mg·kg^(-1) of 463 inhibited about 75%of tumor growth in vivo in a MC38 transgenic xenograft mice model,which was similar to the activity of ATE.More interestingly,an even lower dose of 463(2 mg·kg^(-1))showed a better effect than 10 mg·kg^(-1) of WT PD-1.This work offers the decoy 463 with an improved curative effect,which holds potential to become a good option against PD-1/PD-L1-related cancers. | Hao Liu Chunxia Qiao Naijing Hu Zhihong Wang Jing Wang Jiannan Feng Beifen Shen Yuanfang Ma Longlong Luo | 2021 | Engineering2021，7，11： | 0 |
| 6 | Reliability and consistency assessment of land cover products atmacro and local scales in typical cities显示文摘Urban areas have higher heterogeneity compared to natural areas,it is crucial to assessfine-resolution land cover products and discover how they differ in urban areas so that they can be efficiently used for various application scenarios.In this study,five typical cities in China were chosen as study areas to evaluate four commonly used 30 m land cover products:GLC_FCS30-2020,FROM-GLC30-2017,Globeland30-2020,and CLCD-2019.We analyzed the reliability of these four products using validation samples as well as by examining their area and spatial pattern consistency.Given the limitations of traditional accuracy assessments at the macro level,we added a local area evaluation to further examine the classification details in these products.The macro results indicated that four land cover products within urban areas have a similar overall accuracy,surpassing 76%,but there was a low consistency among them,ranging from 42.21%to 61.13%.The local accuracy assessment illustrated that GLC_FCS30-2020 and FROM-GLC30-2017 performed well in reflecting the intricate details of the city,however,the four products exhibited varying degrees of misclassifications and omissions.These phenomena suggest that more sophisticated algorithms are needed to consider urban particularities sincefine-resolution land cover products may fail to capture complex urban details. | Wenxi Shi Xiang Zhao Jiacheng Zhao Siqing Zhao Yinkun Guo Naijing Liu Na Sun Xiaozheng Du Mengmeng Sun | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 7 | Potential Distribution of Seagrass Meadows Based on the MaxEnt Model in Chinese Coastal Waters显示文摘Seagrass meadows are generally diverse in China and have become important ecosystem with essential functions.However,the seagrass distribution across the seawaters of China has not been evaluated,and the magnitude and direction of changes in seagrass meadows remain unclear.This study aimed to provide a nationwide seagrass distribution map and explore the dynamic changes in seagrass population under global climate change.Simulation studies were performed using the modeling software MaxEnt with 58961 occurrence records and 27 marine environmental variables to predict the potential distribution of seagrasses and calculate the area.Seven environmental variables were excluded from the modeling processes based on a correlation analysis to ensure predicted suitability.The predicted area was 790.09 km^(2),which is much larger than the known seagrass distribution in China(87.65 km^(2)).By 2100,the suitable habitat of seagrass will shift northwest and increase to 923.62 km2.Models of the sum of the individual family under-pre-dicted the national distribution of seagrasses and consistently showed a downward trend in the future.Out of all environmental vari-ables,physical parameters(e.g.,depth,land distance,and sea surface temperature)contributed the most in predicting seagrass distri-butions,and nutrients(e.g.,nitrate,phosphate)ranked among the key influential predictors for habitat suitability in our study area.This study is the first effort to fill a gap in understanding the distribution of seagrasses in China.Further studies using modeling and biological/ecological approaches are warranted. | WANG Ming WANG Yong LIU Guangliang CHEN Yuhu YU Naijing | 2022 | Journal of Ocean University of China2022，21，5： | 0 |
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