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| 1 | Stem cell-based therapy for human diseases显示文摘Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be treated.Stem cell-based therapy,including human pluripotent stem cells(hPsCs)and multipotent mesenchymal stem cells(MSCs),has recently emerged as a key player in regenerative medicine.hPSCs are defined as self-renewable cell types conferring the ability to differentiate into various cellular phenotypes of the human body,including three germ layers.MsCs are multipotent progenitor cells possessing self-renewal ability(limited in vitro)and differentiation potential into mesenchymal lineages,according to the International Society for Cell and Gene Therapy(ISCT).This review provides an update on recent clinical applications using either hPSCs or MSCs derived from bone marrow(BM),adipose tissue(AT),or the umbilical cord(UC)for the treatment of human diseases,including neurological disorders,pulmonary dysfunctions,metabolic/endocrine-related diseases,reproductive disorders,skin burns,and cardiovascular conditions.Moreover,we discuss our own clinical trial experiences on targeted therapies using MsCs in a clinical setting,and we propose and discuss the MSC tissue origin concept and how MSC origin may contribute to the role of MSCs in downstream applications,with the ultimate objective of facilitating translational research in regenerative medicine into clinical applications.The mechanisms discussed here support the proposed hypothesis that BM-MSCs are potentially good candidates for brain and spinal cord injury treatment,AT-MSCs are potentially good candidates for reproductive disorder treatment and skin regeneration,and UC-MsCs are potentially good candidates for pulmonary disease and acute respiratory distress svndrometreatment. | Duc M.Hoang Phuong T.Pham Trung Q.Bach Anh T.L.Ngo Quyen T.Nguyen Trang T.K.Phan Giang H.Nguyen Phuong T.T.Le Van T.Hoang Nicholas R.Forsyth Michael Heke Liem Thanh Nguyen | 2022 | Signal Transduction and Targeted Therapy2022，7，9： | 7 |
| 2 | Activated carbon/Fe 3 O 4 nanoparticle composite: Fabrication, methyl orange removal and regeneration by hydrogen peroxide显示文摘 | Manh Huy Do Ngoc Hoa Phan Thi Dung Nguyen Thi Thu Suong Pham Van Khoa Nguyen Thi Thuy Trang Vu Thi Kim Phuong Nguyen | 2011 | Chemosphere2011，，8： | 2 |
| 3 | Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack显示文摘Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract(ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its inhibitory activities against nitric oxide(NO) production and inducible nitric oxide synthase(iN OS) and cyclooxygenase2(COX-2) expressions in lipopolysaccharide(LPS)-stimulated RAW264.7 cells. The level of NO produced in the culture media was determined by Griess method. The i NOS and COX-2 protein expressions were analyzed by Western blot. The in vivo effect of ELA was evaluated on LPS-induced septic shock in mice model. Mice mortality was monitored for5 days after injection of LPS. The chemical contents of the ELA were determined by using various chromatographic and spectroscopic techniques. Results: The ELA was found to exhibit a significant anti-inflammatory effect in both in vitro and in vivo models. The results demonstrated that ELA dose-dependently inhibited LPS-induced NO production as well as the protein iN OS and COX-2 expressions. In the septic shock model, ELA dose-dependently protected mice from LPS-induced mortality. Further study on the isolated components of ELA indicated that 9,10-dimethoxycanthin-6-one may contribute significantly to the antiinflammatory effects of the extract. Conclusions: These results suggest that ELA exhibits the anti-inflammatory activity via suppression of pro-inflammatory mediators such as NO, iN OS,and COX-2 and protects mice from LPS-induced mortality in septic shock model. | Dao Thi Thanh Hien Tran Phi Long Tran Phuong Thao Jeong-Hyung Lee Duong Thu Trang Nguyen Thi Thu Minh Pham Van Cuong Do Thi Ngoc Lan Nguyen Hai Dang Nguyen Tien Dat | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，1： | 1 |
| 4 | Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease显示文摘 | Wei Zhang Marli S.P. Azevedo Ana M. Gonzalez Linda J. Saif Trang Van Nguyen Ke Wen Ahmed E. Yousef Lijuan Yuan | 2007 | Veterinary Immunology and Immunopathology2007，，1： | 1 |
| 5 | Mucosal and systemic antibody responses and protection induced by a prime/boost rotavirus-DNA vaccine in a gnotobiotic pig model显示文摘 | Lijuan Yuan Marli S.P. Azevedo Ana M. Gonzalez Kwang-il Jeong Trang Van Nguyen Peggy Lewis Cristiana Iosef John E. Herrmann Linda J. Saif | 2005 | Vaccine2005，，30： | 1 |
| 6 | Adsorption and removal of arsenic from water byiron ore mining waste显示文摘 | Tien Vinh Nguyen Thi Van Trang Nguyen Tuan Linh P-ham | 2009 | Water Science&Technology2009，60，9： | 1 |
| 7 | Incidence and epidemiologyof intussusception among infants in Ho Chi Minh City,Vietnam显示文摘 | Van Trang N Le Nguyen N T Dao H T | 2014 | The Journal of pediatrics2014，164，2： | 1 |
| 8 | 夏黑葡萄在越南北部栽培表现及其技术要点显示文摘河内、北江等越南北方地区年均温比广西南宁高2℃左右,光温条件比较优越,应越方要求新引入种植比巨峰葡萄早熟优质的无核夏黑葡萄,以期调节产期,满足市场需求。采用广西夏黑葡萄当年种当年收和一年两收栽培技术管理,在越南北部地区于3月上旬种植夏黑葡萄,种后4个半月于7月下旬修剪促花,剪后1个月于8月下旬开花,剪后2个月于9日下旬着色,剪后3个月于10月中下旬成熟上市,从种到收获全程9个月,平均每hm^2产量8517.0 kg,实现了当年种植当年投产的目标。为越南葡萄产业增加新的经济增长点。 | 黄江流 DO THANH TRUNG 唐其展 吕荣华 NGUYEN TUAN DIEP CAN VAN TOAN NGUYEN CONG THANH PHUNG DUY HIEU BUI THI THU TRANG 黄竟 刘淑仪 黄芳颖 梁芳 黄勇策 黄克顺 | 2019 | 南方园艺2019，30，6： | 1 |
| 9 | Compensation of Zn substitution and secondary phase controls effective mass and weighted mobility in In and Ga co-doped ZnO material显示文摘Conductivity s and thermal conductivity k are directly related to carrier concentration while Seebeck coefficient S is inversely proportional to carrier concentration.Therefore,improving thermoelectric(TE)performance is challenging.Here,the first-time analysis of secondary phase-controlled TE performance in terms of density-of-state effective mass m*d,weighted mobility mw and quality factor B is discussed in ZnO system.The results show that the secondary spinel phase Ga2O_(3)(ZnO)9 not only impacts on k but also on s and S at high temperature,while the effect of carrier concentration seem to be dominant at low temperature.For the high-spinel-segregation sample,a compensation of dopant atoms from the spinel to substitutional sites in the ZnO matrix at high temperature leads to a low decreased rate of temperaturedependent m*d.The compensation process also induces a band sharpening,a small mw reduction,and a large B enhancement.As a result,In and Ga co-doped ZnO bulk with the highest spinel segregation achieves the greatest PF improvement by 112.8%,owing to enhanced Seebeck coefficient by 110%as compared to the good Zn-substitution sample. | Oanh Kieu Truong Le Anh Tuan Thanh Pham Ngoc Kim Pham Trang Huyen Cao Pham Truong Huu Nguyen Dung Van Hoang Hanh Kieu Thi Ta Dai Cao Truong Hoa Thi Lai Thuy Dieu Thi Ung Vinh Cao Tran Thang Bach Phan | 2021 | Journal of Materiomics2021，7，4： | 0 |
| 10 | Influence of Input Factors on Surface Roughness and Material Removal Speed when Wire-EDM a Hardened SKD11 Steel Curve Profile显示文摘The goal of this research is to identify the best set of process machining parameters for wire-EDM(Electrical Discharge Machining)cutting of hardened SKD11 steel when machining a curve profile.The multi-objective function includes reducing surface roughness and increasing MRR(Material Removal Rate).The optimization process is prepared by using Taguchi method coupled Grey Relational Analysis.The obtained results revealed that Toff has the greatest influence on the average grey value(48.30%),followed by the influence of WF(Wire Feed,15.99%),VM(Cutting Voltage,9.33%),SV(Server Voltage,5.05%),Ton(Pulse on Time,1.81%),while SPD(Cutting Speed)has a negligible effect(0.89%).Moreover,using the optimal set of machining parameters generates in surface roughness of 1.25399mm and MRR of 26.5562 mm^(2)/min.The verification experiment and Anderson-Darling method demonstrate the validity of the proposed model,which can be utilized for estimating surface roughness and MRR. | Tran Quoc Hung Nguyen Van Trang | 2023 | Journal of Environmental Science and Engineering(B)2023，12，5： | 0 |
| 11 | A comparative analysis of weight-based machine learning methods for landslide susceptibility mapping in Ha Giang area显示文摘Landslide susceptibility maps (LSMs) are very crucial for planningpolicies in hazardous areas. However, the accuracy and reliability ofLSMs depend on available data and the selection of suitable methods.This study is conducted to produce LSMs by combinations of machinelearning methods and weighting techniques for Ha Giang province,Vietnam, where has limited data. In study area, we gather 11 landslideconditioning factors and establish a landslide inventory map.Computing the weights of classes (or factors) is very important toprepare data for machine learning methods to generate LSMs. Wefrst use frequency ratio (FR) and analytic hierarchy process (AHP)techniques to generate the weights. Then, random forest (RF), supportvector machine (SVM), logistic regression (LR), and AHP methods arecombined with FR and AHP weights to yield accurate and reliableLSMs. Finally, the performance of these methods is evaluated by fivestatistical metrics, ROC and R-index. The empirical results have shownthat RF is the best method in terms of R-index and the five metrics, i.e.TP rate (0.9661), FP rate (0.0), ACC (0.9835), MAE (0.0046), and RMSE(0.0350) for this study area. This study opens the perspective of weightbasedmachine learning methods for landslide susceptibility mapping. | Thanh Trinh Binh Thanh Luu Trang Ha Thi Le Duong Huy Nguyen Trong Van Tran Thi Hai Van Nguyen Khanh Quoc Nguyen Lien Thi Nguyen | 2023 | Big Earth Data2023，7，4： | 0 |
| 12 | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding:A case report显示文摘BACKGROUND Brunner’s gland hyperplasia(BGH)is a rare benign lesion of the duodenum.Lipomatous pseudohypertrophy(LiPH)of the pancreas is an extremely rare disease.Because each condition is rare,the probability of purely coincidental coexistence of both conditions is extremely low.CASE SUMMARY We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal bleeding.Upper gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the lesion.Histopathological examination of the duodenal biopsy specimens showed BGH.Besides,abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas,confirmed by histopathological evaluation on percutaneous pancreatic biopsies.Based on the radiological and histological findings,LiPH of the pancreas and BGH were diagnosed.The patient refused any surgical intervention.Therefore,he was managed with supportive treatment.The patient’s symptoms improved and there was no further bleeding.CONCLUSION This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH. | Long Cong Nguyen Khanh Truong Vu Trang Thi Thuy Vo Chau Ha Trinh Tan Dang Do Ngoc Thi Van Pham Tuyen Van Pham Thanh Tuan Nguyen Hiep Canh Nguyen Jeong-Sik Byeon | 2021 | World Journal of Clinical Cases2021，9，31： | 0 |
| 13 | Analysis of Storm Pattern for Design Urban Drainage System in the Monsoon Areas of Vietnam显示文摘In Vietnam,rainfall data usually received using daily rainfall at all hydrology stations with higher time resolution are scarce.However,its analyses to achieve IDF(Intensity-Duration-Frequency)curves are often required at a finer scale such as hourly.Therefore,it needs to develop and apply methods to derive the IDF characteristics of short-duration events from daily rainfall statistics in Vietnam.In recent years,the need for new insights into the rainfall process leading to new approaches to model the distribution of rainfall intensities in time and space was recognized.This research aims to establish IDF curves for monsoon climate area in Vietnam based on scaling method.Scaling properties of extreme rainfall are examined in the Red River Delta of Vietnam in order to establish scaling behavior of statistical moments over different durations.Such scaling or scale-invariant models enable us to scale data from one temporal resolution to another,and thus,help to overcome the lack of the extreme rainfall data of sub-daily durations.The disaggregation or downscaling techniques are used to obtain sub-daily rainfall data from daily rainfall data for the derivation of scaled IDF curves.Research results show that most of rainfall amount(approximately 70%)received from rains occurring between 6:0 pm to 6:0 am of the day after that,the daytime usually less rainfall occurrence with only 30%.The peak rainfall is usually occurred during 0:0 am to 4:0 am having approximately 42.98%of rainfall amount over a day.The peak rainfall likely happen earlier in the recent year(36%rainfall amount over a day occurrence from 6:00 pm to 10:00 pm in 2008).The analysis also illustrated that approximately 40%of rainfall events have duration less than 60 minutes.In contrast,only approximately 9%of rainfall events have duration more than 6 hours but total rainfall depths of these events is approximately. | Bui Thi Thu Trang Nguyen Thi Hong Hanh Nguyen Thi Hoai Thuong Nguyen Van Thuan | 2018 | Journal of Environmental Science and Engineering(A)2018，7，2： | 0 |
| 14 | Performance Comparison of Chemically Modified Sugarcane Bagasse for Removing Cd(II) in Water Environment显示文摘This paper evaluates the adsorption capacity of chemically sugarcane bagasses with sodium hydroxide(SHS),citric acid(CAS),tartaric acid(TAS)and unmodified sugarcane bagasse(SB)for cadmium adsorption in water environment.The results prove adsorption capacity for Cd(II)increases after chemical modification and the adsorption fits perfectly with the Langmuir isotherm.CAS had the highest maximum adsorption capacity of 45.45 mg/g followed by TAS with 38.46 mg/g and SHS with 29.41 at optimum pH 5.0 and 120 minutes equilibrium time while 1 g SB removed 18.8 mg Cd(II)in the same conditions.The kinetics study of the process followed a pseudo-secondorder rate expression,that indicated a strong interaction between the biosorbents and adsorbate.The sugarcane bagasse and modified sugarcane bagasse were characterized by scanning electron microscopy(SEM)and Fourier transform infrared spectroscopy(FTIR)analysis.The chemical modification was confirmed by the presence of carboxyl and esters groups created at 1,738 cm-1.The estimation of acid groups in modified materials shows the enhancement of this group after modification.On the other hand,desorption studies showed the high leaching of cadmium ion from the biosorbent leading to the efficient reutilization of materials. | Manh Khai Nguyen Minh Trang Hoang Thi Thuy Pham Bart Van der Bruggen | 2019 | Journal of Renewable Materials2019，7，5： | 0 |
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