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| 1 | Neoatherosclerosis:Coronary stents seal atherosclerotic lesions but result in making a new problem of atherosclerosis显示文摘Chronic inflammation of the native vessel wall with infiltration of lipid-laden foamy macrophages through impaired endothelium results in atherosclerosis. Percutaneous coronary intervention, including metallic stent implantation, is now widely utilized for the treatment of atherosclerotic lesions of the coronary artery. Baremetal stents and the subsequently developed drugeluting stents seal the atherosclerosis and resolve lumen stenosis or obstruction of the epicardial coronary artery and myocardial ischemia. After stent implantation, neointima proliferates within the stented segment. Chronic inflammation caused by a foreign body reaction to the implanted stent and subsequent neovascularization, which is characterized by the continuous recruitment of macrophages into the vessel, result in the transformation of the usual neointima into an atheromatous neointima. Neointima with an atherosclerotic appearance, such as that caused by thin-cap fibroatheromas, is now recognized as neoatherosclerosis, which can sometimes cause in-stent restenosis and acute thrombotic occlusion originating from the stent segment following disruption of the atheroma. Neoatherosclerosis is emerging as a new coronary stent-associated problem that has not yet been resolved. In this review article, we will discuss possible mechanisms, clinical challenges, and the future outlook of neoatherosclerosis. | Hidenori Komiyama Masamichi Takano Noritake Hata Yoshihiko Seino Wataru Shimizu Kyoichi Mizuno | 2015 | World Journal of Cardiology2015，7，11： | 7 |
| 2 | Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a valuable diagnostic marker for rupture of thin-cap fibroatheroma: Verification by optical coherence tomography显示文摘 | Nobuaki Kobayashi Masamichi Takano Noritake Hata Noriaki Kume Masanori Yamamoto Shinya Yokoyama Takuro Shinada Kazunori Tomita Akihiro Shirakabe Toshiaki Otsuka Yoshihiko Seino Kyoichi Mizuno | 2013 | International Journal of Cardiology2013，，： | 2 |
| 3 | 尼可地尔治疗急性心衰患者的有效性和安全性显示文摘(接8月下)
3.3使用其他血管扩张剂与尼可地尔的治疗相结合有机硝酸盐类首先扩张静脉系统而不是微动脉。相反地,尼可地尔能够通过达到静脉系统和动脉血管扩张平衡来产生最佳的效果,减轻系统血管阻力。 | Akihiro Shirakabe Noritake Hata Shinya Yokoyama Takuro Shinada Nobuaki Kobayashi Kuniya Asai Kyoichi Mizuno 刘栋(译) | 2016 | 首都食品与医药2016，，18： | 1 |
| 4 | Soluble lection-like oxidized low-density lipoprotein receptor-1 as an early biomarker for ST elevation myocardial infarction-time-dependent comparisons with other biomarkers显示文摘 | Nobuaki Kobayashi Noritake Hata Noriaki Kume | | 0，，06： | 1 |
| 5 | Soluble lection-like oxidized low-density lipoprotein receptor-1 and high-sensitivity troponin T as diagnostic biomarkers for acute coronary syndrome-improved values with combination usage in emergency rooms显示文摘 | Nobuaki Kobayashi Noritake Hata Noriaki Kume | | 0，，12： | 1 |
| 6 | The possibility of delayed arterial healing 5 years after implantation of sirolimus-eluting stents: Serial observations by coronary angioscopy显示文摘 | Masanori Yamamoto Masamichi Takano Daisuke Murakami Toru Inami Nobuaki Kobayashi Sigenobu Inami Kentaro Okamatsu Takayoshi Ohba Chikao Ibuki Noritake Hata Yoshihiko Seino Ik-Kyung Jang Kyoichi Mizuno | 2011 | American Heart Journal2011，，6： | 1 |
| 7 | Soluble Lection-Like Oxidized Low-Density Lipoprotein Receptor-1 as an Early Biomarker for ST Elevation Myocardial Infarction-Time-Dependent comparisons With Other Biomarkers显示文摘 | Nobuaki Kobayashi Noritake Hata Noriaki Kume | | 0，，： | 1 |
| 8 | 尼可地尔治疗急性心衰患者的有效性和安全性显示文摘急性心衰(AHF)患者由于急性肺水肿造成急性呼吸衰竭性供氧不足逐渐或者快速转变为心衰(HF)的信号或症状。欧洲心脏病协会出版的指导原则推荐未合并极低血压的患者应用扩血管药物优于离子通道药物。急性心衰急性期运用硝酸酯类药物治疗是黄金定律,然而却少有报道尼可地尔治疗急性心衰的有效性。尼可地尔既具有类硝酸酯特性又能激活ATP-敏感的钾离子通道从而平衡静脉和动脉的舒张。文献证明肺动脉导管介入动态监测的慢性心衰患者静脉快滴尼可地尔可改善血液流变学参数。Minami等进一步研究表明,使用非介入心脏血流变监测的急性心衰患者在急性期使用尼可地尔的治疗有效性。 | Akihiro Shirakabe(日本) Noritake Hata(日本) Shinya Yokoyama(日本) Takuro Shinada(日本) Nobuaki Kobayashi(日本) Kuniya Asai(日本) Kyoichi Mizuno(日本) 刘栋(译) | 2016 | 首都食品与医药2016，0，10： | 1 |
| 9 | Immediate administration of tolvaptan prevents the exac- erbation of acute kidney injury and improves the mid-term prognosis of patients with severely decompensated acute heart failure 显示文摘 | Akihiro Shil'akabe Noritake Hata Masanori Yamamoto | 2014 | Circ2014，78，91： | 1 |
| 10 | New scoring system (APACHE-HF) for predicting adverse outcomes in patients with acute heart failure: Evaluation of the APACHE II and Modified APACHE II scoring systems显示文摘 | Hirotake Okazaki Akihiro Shirakabe Noritake Hata Masanori Yamamoto Nobuaki Kobayashi Takuro Shinada Kazunori Tomita Masafumi Tsurumi Masato Matsushita Yoshiya Yamamoto Shinya Yokoyama Kuniya Asai Wataru Shimizu | 2014 | Journal of Cardiology2014，，： | 1 |
| 11 | 尼可地尔治疗急性心衰患者的有效性和安全性显示文摘附表2列出31例患者的临床表现。大多患者属于NYHA四类(84%),端坐呼吸(90%),啰音(97%)。阵发性夜间呼吸困难,端坐呼吸,啰音,心旁音,颈静脉扩张,和外周性水肿等生理性发现率两组之间不存在持续性差别。2.2 NT-pro-BNP,BNP和尼可地尔疗法实验第一天尼可地尔实验组(1397.0±1617.5, | Akihiro Shirakabe Noritake Hata Shinya Yokoyama Takuro Shinada Nobuaki Kobayashi Kuniya Asai Kyoichi Mizuno 刘栋(译) | 2016 | 首都食品与医药2016，0，14： | 0 |
| 12 | 尼可地尔治疗急性心衰患者的有效性和安全性显示文摘(接7月下)
然而尼可地尔2007年在日本批准用于急性心衰患者,该病患者运用尼可地尔潜在的用处还未被发现。 | Akihiro Shirakabe Noritake Hata Shinya Yokoyama Takuro Shinada Nobuaki Kobayashi Kuniya Asai Kyoichi Mizuno 刘栋(译) | 2016 | 首都食品与医药2016，0，16： | 0 |
| 13 | 尼可地尔治疗急性心衰患者的有效性和安全性显示文摘(接5月下)我们通过超声心动显像仪来评价左心室的几何结构变化,包括实验组和对照组的左心室体积变化。第三实验目的通过监测给药尼可地尔后血液动力学的变化来确定尼可地尔的安全性。 | Akihiro Shirakabe Noritake Hata Shinya Yokoyama Takuro Shinada Nobuaki Kobayashi Kuniya Asai Kyoichi Mizuno 刘栋 | 2016 | 首都食品与医药2016，0，12： | 0 |
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