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| 1 | Modeling sarcomagenesis using multipotent mesenchymal stem cells显示文摘因为他们的唯一的性质,间充质的干细胞(MSC ) 代表最有希望的成年干细胞之一在临床的应用的一个宽数组全球正在被使用的 multipotent。总的来说,引人注目的证据支持前 vivo 的长期的安全扩展了人的 MSC,它不似乎自发地转变。然而,试验性的数据表明在 MSC 和癌症之间的一个连接,和 MSC 被报导了禁止或支持肿瘤生长取决于还未定义的条件。有趣地,稳固的证据为某些肉瘤基于转基因的老鼠和 MSC 的基因干预把这些房间放作为起源的最可能的房间。这个研究区域逐渐地正在被探索开发 sarcomagenesis 的精确基于 MSC 的模型,它将在关于间充质的癌症的病原学和致病提供更好的理解无疑是珍贵的,最后导致更特定的治疗的发展对开始肉瘤的房间指导了。不幸地,仍然,很少对位于 MSC 转变下面的机制被知道,进一步的研究被要求基于人的 MSC 开发真正的肉瘤模型。这里,我们包括地考察存在肉瘤的基于 MSC 的模型并且讨论导致 MSC 和 sarcomagenesis 的 tumoral 转变的最普通的机制。 | Rene Rodriguez Ruth Rubio Pablo Menendez | 2012 | Cell Research2012,22,1: | 8 |
| 2 | New frontiers for the materials genome initiative显示文摘The Materials Genome Initiative(MGI)advanced a new paradigm for materials discovery and design,namely that the pace of new materials deployment could be accelerated through complementary efforts in theory,computation,and experiment.Along with numerous successes,new challenges are inviting researchers to refocus the efforts and approaches that were originally inspired by the MGI.In May 2017,the National Science Foundation sponsored the workshop“Advancing and Accelerating Materials Innovation Through the Synergistic Interaction among Computation,Experiment,and Theory:Opening New Frontiers”to review accomplishments that emerged from investments in science and infrastructure under the MGI,identify scientific opportunities in this new environment,examine how to effectively utilize new materials innovation infrastructure,and discuss challenges in achieving accelerated materials research through the seamless integration of experiment,computation,and theory.This article summarizes key findings from the workshop and provides perspectives that aim to guide the direction of future materials research and its translation into societal impacts. | Juan J.de Pablo Nicholas E.Jackson Michael A.Webb Long-Qing Chen Joel E.Moore Dane Morgan Ryan Jacobs Tresa Pollock Darrell G.Schlom Eric S.Toberer James Analytis Ismaila Dabo Dean M.DeLongchamp Gregory A.Fiete Gregory M.Grason Geoffroy Hautier Yifei Mo Krishna Rajan Evan J.Reed Efrain Rodriguez Vladan Stevanovic Jin Suntivich Katsuyo Thornton Ji-Cheng Zhao | 2019 | npj Computational Materials2019,,1: | 7 |
| 3 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021,20,2: | 5 |
| 4 | A linear assisted DC/DC converter for envelope tracking and envelope elimination and restoration applications显示文摘 | Pablo F Miaja Miguel Rodriguez Alberto Rodriguez | 2012 | IEEE Transactions on Power Electronics2012,27,7: | 1 |
| 5 | Imaging Crohn Disease: MR Enterography显示文摘 | Pablo Rodriguez Ramiro Mendez Fatima Matute Paula Hernandez Juan Luis Mendoza | 2014 | Journal of Computer Assisted Tomography2014,,: | 1 |
| 6 | Cascaded multilevel inverter with regeneration capability and reduced number of switches显示文摘 | Lezana Pablo Rodriguez Jose Oyarz6n Diego A | 2008 | IEEE Transactions on Industry Appli- cations2008,55,3: | 1 |
| 7 | A Vector Control Technique for Medium Voltage Multilevel Inverters显示文摘 | Rodriguez Jo se Moran Luis Correa Pablo | 2002 | IEEE Trans on Industrial Electronics2002,49,4: | 1 |
| 8 | New tools for rock art modelling: automated sensor integration in Pindal Cave 显示文摘 | Diego Gonzalez - Aguilera Angel Munoz - Nieto Pablo Rodriguez - Gonzalvez Diego | 2011 | J Archaeol Sci2011,38,: | 1 |
| 9 | A High Performance Vector Control of an 11-Level Inverter显示文摘 | Rodriguez Jo se Moran Luis Correa Pablo | 2003 | IEEE Trans on Industrial Electronics2003,50,1: | 1 |
| 10 | A frac- tional porous medium equation 显示文摘 | de Pablo A Qui6s F Rodriguez A | 2011 | Adv Math2011,226,2: | 1 |
| 11 | Muscle weakness in septic patients requiring mechanical ventilation:Protective effect of transcutaneous neuromuscular electrical stimulation显示文摘 | Pablo O Rodriguez Mariano Setten Luis P Maskin | 2012 | J Crit Care2012,27,3: | 1 |
| 12 | A simple dot- blot- Sirius red- based assay for collagen quantification显示文摘 | Rodriguez- Rodriguez P Arribas S M L6pez de Pablo A L | 2013 | Analytical and Bioanalytical Chemistry2013,405,: | 1 |
| 13 | Laparoscopic Approach for Isolated Splenic Metastasis: Comprehensive Literature Review and Report of 6 Cases显示文摘 | Julio Lopez Monclova Eduardo Targarona Soler Yerald Peraza Solis Pablo Vidal Gonzalez Carmen Balague Ponz Carlos Rodriguez Luppi Manuel Trias Folch | 2013 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2013,,1: | 1 |
| 14 | Sweat-Based in Vitro Diagnostics(IVD):From Sample Collection to Point-of-Care Testing(POCT)显示文摘Sweat-based diagnostics offer an exciting avenue to noninvasively monitor analytes which had previously only been avail-able through painful blood draws.Sweat is enriched with physiologically valuable information,and recent proteomic studies have identified numerous critical analytes which have highly correlated levels in blood,interstitial fluid and sweat.How-ever,usage of sweat for health monitoring has not been studied extensively due to the substantial challenge of assembling a composite clinic-ready device.Recent advances in soft electronics have made this goal realizable,as these devices can perform electronic or optical monitoring on a flexible substrate using small volumes of liquid.While this field is still in its infancy,this review examines the physiological composition of sweat,various improvements in material science that improve sensor design,existing FDA approvals,methods of extracting sweat and comparisons to blood-based tests.Furthermore,this review assesses the critical challenges which must be overcome for this type of technology to make it out of research laboratories and into continuous clinical use.We believe that once properly harnessed,sweat-based diagnostics can provide patients a painless monitoring tool which can be customized to track a wide variety of medical conditions from the comfort of a patient’s own home. | Mehenur Sarwar Pablo Rodriguez Chen-zhong Li | 2019 | Journal of Analysis and Testing2019,3,1: | 1 |
| 15 | Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip显示文摘 | Philippa J. Talmud Fotios Drenos Sonia Shah Tina Shah Jutta Palmen Claudio Verzilli Tom R. Gaunt Jacky Pallas Ruth Lovering Kawah Li Juan Pablo Casas Reecha Sofat Meena Kumari Santiago Rodriguez Toby Johnson Stephen J. Newhouse Anna Dominiczak Nilesh J. S | 2009 | The American Journal of Human Genetics2009,,5: | 1 |
| 16 | Control of a single-phase cascaded H-bridge multilevel inverter for grid-connected photovoltaic systems显示文摘 | Elena Villanueva Pablo Correa Jos6 Rodriguez | 2009 | IEEE Transactions on Industry Electronics2009,6,11: | 1 |
| 17 | A vector control technique for medium-voltage multilevel inverters显示文摘 | Rodriguez Jose Moran Luis Correa Pablo | 2002 | IEEE Trans on Industrial Electronics2002,49,4: | 1 |
| 18 | A high-performance vector control of an 11-level inverter显示文摘 | Rodriguez Jose Moran Luis Correa Pablo | 2003 | IEEE Trans on Industrial Electronics2003,50,1: | 1 |
| 19 | Control of a Single-phase Cascaded H- Bridge Multilevel Inverter for Grid-Connected Photovoltaic Systems 显示文摘 | Elena Villanueva Pablo Correa Jose Rodriguez | 2009 | IEEE Trans On Indus- trial Electronics2009,56,11: | 1 |
| 20 | HYDRAULIC ANALYSES FOR A NEW BRIDGE OVER THE PARANA RIVER, ARGENTINA显示文摘This paper summarizes hydraulic studies carried out as part of the feasibility study for a new bridge over the Parana River in Argentina. The bridge will physically connect the provinces of Santa Fe and Corrientes, currently separated over the length a 200-km river reach. In addition to the hydraulic studies summarized here, the feasibility study includes analyses of the geology and geomorphology of the sites, land surveying, geophysical and hydrologic studies, studies of the navigation channel and fluvial transportation, transportation studies, and environmental impact studies. The main components of the present study were a geomorphologic analysis of the middle reach of the Parana River, and a quantitative hydraulic study. Qualitative and quantitative analyses provided a description of the hydraulic system, and served as a basis for a comparison of alternative bridge locations and the analysis of their vulnerability. The quantitative hydraulic study included the construction, calibration, and operation of one-dimensional (1D) and depth-averaged two-dimensional (2D) flow models. In order to tie the models to the most reliable data the 1D models covered a 450-km long reach, and included the main channel (about 2 km wide) and the flood plain (about 30 km wide). The results of the 1D models played a major role in the selection of the bridge location, and were subsequently used as boundary conditions for 2D modeling. The 2D models were constructed for a 70 km x 30 km modeling domain. This paper presents results of 1D modeling for large floods, both in the natural state and with the proposed bridge, and results of 2D modeling in the natural state. Modeling at this scale requires sound judgment to strike a balance between the desirable level of model detail and the cost of acquiring data for model construction and calibration. | André RODRIGUEZ Daniel BREA Daniel Farís Hétor R. BRAVO Edgar Castelló Gerardo HILLMAN Juan WEBER Mariana PAGOT Pablo SPALLETTI | 2003 | International Journal of Sediment Research2003,18,2: | 1 |