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| 1 | Development of noise and vibration prediction software in medium-to-high frequency ranges using power flow boundary element method显示文摘 | Howon Lee Dohyun Park Sukyoo Hong | 2003 | SAE2003,,: | 1 |
| 2 | Parametric sensitivity analysis of ground uplift abovepressurized underground rock caverns显示文摘 | Kim Hyung-Mok Park Dohyun Ryu Dong-Woo etal | 2012 | EngineeringGeology2012,,: | 1 |
| 3 | Reduction of blast-induced vibration in the direction of tunneling using an air-deck at the bottom of a blastbole显示文摘 | Dohyun Park SeokwonJeon | 2010 | International Journal of Rock Mechanics & Mining Sciences2010,,47: | 1 |
| 4 | U-IMPACT:a universal 3D microfluidic cell culture platform显示文摘The development of organs-on-a-chip has resulted in advances in the reconstruction of 3D cellular microenvironments.However,there remain limitations regarding applicability and manufacturability.Here,we present an injection-molded plastic array 3D universal culture platform(U-IMPACT)for various biological applications in a single platform,such as cocultures of various cell types,and spheroids(e.g.,tumor spheroids,neurospheres)and tissues(e.g.,microvessels).The U-IMPACT consists of three channels and a spheroid zone with a 96-well plate form factor.Specifically,organoids or spheroids(~500μm)can be located in designated areas,while cell suspensions or cellladen hydrogels can be selectively placed in three channels.For stable multichannel patterning,we developed a new patterning method based on capillary action,utilizing capillary channels and the native contact angle of the materials without any modification.We derived the optimal material hydrophilicity(contact angle of the body,45–90°;substrate,<30°)for robust patterning through experiments and theoretical calculations.We demonstrated that the U-IMPACT can implement 3D tumor microenvironments for angiogenesis,vascularization,and tumor cell migration.Furthermore,we cultured neurospheres from induced neural stem cells.The U-IMPACT can serve as a multifunctional organ-on-achip platform for high-content and high-throughput screening. | Seung-Ryeol Lee Youngtaek Kim Suryong Kim Jiho Kim Seonghyuk Park Stephen Rhee Dohyun Park Byungjun Lee Kyusuk Baek Ho-Young Kim Noo Li Jeon | 2022 | Microsystems & Nanoengineering2022,8,6: | 0 |
| 5 | An effective method to generate controllable levels of ROS for the enhancement of HUVEC proliferation using a chlorin e6-immobilized PET film as a photo-functional biomaterial显示文摘Reactive oxygen species(ROS)are byproducts of cellular metabolism;they play a significant role as secondary messengers in cell signaling.In cells,high concentrations of ROS induce apoptosis,senescence,and contact inhibition,while low concentrations of ROS result in angiogenesis,proliferation,and cytoskeleton remodeling.Thus,controlling ROS generation is an important factor in cell biology.We designed a chlorin e6(Ce6)-immobilized polyethylene terephthalate(PET)film(Ce6-PET)to produce extracellular ROS under red-light irradiation.The application of Ce6-PET films can regulate the generation of ROS by altering the intensity of light-emitting diode sources.We confirmed that the Ce6-PET film could effectively promote cell growth under irradiation at 500 μW/cm^(2) for 30 min in human umbilical vein endothelial cells.We also found that the Ce6-PET film is more efficient in generating ROS than a Ce6-incorporated polyurethane film under the same conditions.Ce6-PET fabrication shows promise for improving the localized delivery of extracellular ROS and regulating ROS formation through the optimization of irradiation intensity. | Seung Hee Hong Min-Ah Koo Mi Hee Lee Gyeung Mi Seon Ye Jin Park HaKyeong Jeong Dohyun Kim Jong-Chul Park | 2021 | Regenerative Biomaterials2021,8,2: | 0 |
| 6 | Graphene-based saturable absorber and mode-locked laser behaviors under gamma-ray radiation显示文摘We investigate optical and electrical behaviors of a graphene saturable absorber (SA) and mode-locking performance of a graphene-SA-based mode-locked Er fiber laser in gamma-ray radiation. When irradiated up to 4.8 kGy at ~ 100 Gy/hr dose rate, the overall nonlinear transmittance in transverse electric mode was increased, while maintaining modulation depth to >10%. The corresponding polarization.dependent loss was reduced at a 1.2-dB/kGy rate. In the electrical properties, the charge carrier mobility was reduced, and the Dirac voltage shift was increased to positive under gamma-ray radiation. The radiation-induced optical and electrical changes turned out to be almost recovered after a few days. In addition, we confirmed that the graphene-SA-based laser showed stable CW mode-locking operation while the inserted graphene SA was irradiated for 2-kGy at a 45-Gy/hr dose rate, which corresponds to >40 years of operation in low Earth orbit satellites.To the best of our knowledge, this is the first evaluation of graphene SAs and graphene-SA-based mode-locked lasers in gamma-ray radiation, and the measured results confirm the high potential of graphene SAs and graphene-SA-based lasers in various outer-space environments as well as other radiation environments, including particle accelerators and radiationbased medical instruments. | Dohyun Kim Nam Hun Park Hyunju Lee Jaegoan Lee Dong-Il Yeom Jungwon Kim | 2019 | Photonics Research2019,7,7: | 0 |