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| 1 | Research progress in ZnO single-crystal:growth, scientific understanding, and device applications显示文摘Zinc oxide,a wide band-gap semiconductor,has shown extensive potential applications in high-efficiency semiconductor photoelectronic devices,semiconductor photocatalysis,and diluted magnetic semiconductors.Due to the undisputed lattice integrity,ZnO single crystals are essential for the fabrication of high-quality ZnO-based photoelectronic devices,and also believed to be ideal research subjects for understanding the underlying mechanisms of semiconductor photocatalysis and diluted magnetic semiconductors.This review,which is organized in two main parts,introduces the recent progress in growth,basic characterization,and device development of ZnO single crystals,and some related works in our group.The first part begins from the growth of ZnO single crystal,and summarizes the fundamental and applied investigations based on ZnO single crystals.These works are composed of the fabrication of homoepitaxial ZnO-based photoelectronic devices,the research on the photocatalysis mechanism,and dilute magnetic mechanism.The second part describes the fabrication of highly thermostable n-type ZnO with high mobility and high electron concentration through intentional doping.More importantly,in this part,a conceptual approach for fabricating highly thermostable p-type ZnO materials with high mobility through an integrated three-step treatment is proposed on the basis of the preliminary research. | Feng Huang Zhang Lin Wenwen Lin Jiye Zhang Kai Ding Yonghao Wang Qinghong Zheng Zhibing Zhan Fengbo Yan Dagui Chen Peiwen Lv Xian Wang | 2014 | Chinese Science Bulletin2014，59，12： | 11 |
| 2 | Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics显示文摘Civets are small mammals belonging to the family Viverridae.The masked palm civets(Paguma larvata)served as an intermediate host in the bat-to-human transmission of severe acute respiratory syndrome coronavirus(SARS-Co V)in 2003(Guan et al.,2003).Because of their unique role in the SARS outbreak,civets were suspected as a potential intermediate host of SARS-Co V-2. | Peiwen Ding Haoyu Wang Jiacheng Zhu Fuyu An Jinqian Xu Xiangning Ding Lihua Luo Weiying Wu Qiuyu Qin Yanan Wei Wandong Zhao Zhiyuan Lv Haimeng Li Yixin Zhu Meiling Li Wensheng Zhang Yanan Zhang Zhihua Ou Huan Liu Yan Hua | 2022 | Journal of Genetics and Genomics2022，49，11： | 0 |
| 3 | A chromosome-level genome assembly for Dracaena cochinchinensis reveals the molecular basis of its longevity and formation of dragon’s blood显示文摘Dracaena,a remarkably long-lived and slowly maturing species of plant,is world famous for its ability to produce dragon’s blood,a precious traditional medicine used by different cultures since ancient times.However,there is no detailed and high-quality genome available for this species at present;thus,the molecular mechanisms that underlie its important traits are largely unknown.These factors seriously limit the protection and regeneration of this rare and endangered plant resource.Here,we sequenced and assembled the genome of Dracaena cochinchinensis at the chromosome level.The D.cochinchinensis genome covers 1.21 Gb with a scaffold N50 of 50.06 Mb and encodes 31619 predicted protein-coding genes.Analysis showed that D.cochinchinensis has undergone two whole-genome duplications and two bursts of long terminal repeat insertions.The expansion of two gene classes,cis-zeatin O-glucosyltransferase and small auxin upregulated RNA,were found to account for its longevity and slow growth.Two transcription factors(bHLH and MYB)were found to be core regulators of the flavonoid biosynthesis pathway,and reactive oxygen species were identified as the specific signaling molecules responsible for the injuryinduced formation of dragon’s blood.Our study provides high-quality genomic information relating to D.cochinchinensis and significant insight into the molecular mechanisms responsible for its longevity and formation of dragon’s blood.These findings will facilitate resource protection and sustainable utilization of Dracaena. | Yanhong Xu Kaijian Zhang Zhonglian Zhang Yang Liu Feifei Lv Peiwen Sun Shixi Gao Qiuling Wang Cuicui Yu Jiemei Jiang Chuangjun Li Meifang Song Zhihui Gao Chun Sui Haitao Li Yue Jin Xinwei Guo Jianhe Wei | 2022 | Plant Communications2022，3，6： | 0 |
| 4 | Precision medicine in the treatment of colorectal cancer with liver metastases显示文摘Colorectal cancer(CRC),one of the most common malignant diseases,ranks second in morbidity and third in mortality among all cancers worldwide1.The liver is the most common site of distant metastasis in CRC.Liver metastasis is also the main cause of death in patients with CRC.Approximately 25%of patients with CRC have liver metastasis detected at the initial diagnosis,and approximately 50%of patients eventually develop liver metastasis during disease progression.Liver metastasis severely affects the prognosis of patients with CRC. | Yuqiu Xu Yang Lv Zhehui Zhu Yijiao Chen Peiwen Zhou Lechi Ye Wentao Tang Jianmin Xu | 2023 | Cancer Biology & Medicine2023，20，12： | 0 |
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