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| 1 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 2 | Jasmonic acid carboxyl methyltransferase regulates development and herbivory-induced defense response in rice显示文摘Jasmonic acid(JA) and related metabolites play a key role in plant defense and growth. JA carboxyl methyltransferase(JMT) may be involved in plant defense and development by methylating JA to methyl jasmonate(Me JA) and thus influencing the concentrations of JA and related metabolites. However, no JMT gene has been well characterized in monocotyledon defense and development at the molecular level. After we cloned a rice JMT gene,Os JMT1, whose encoding protein was localized in the cytosol, we found that the recombinant Os JMT1 protein catalyzed JA to Me JA. Os JMT1 is up-regulated in response to infestation with the brown planthopper(BPH; Nilaparvata lugens). Plants in which Os JMT1 had been overexpressed(oeJMT plants) showed reduced height and yield. These oe-JMT plants also exhibited increased Me JA levels but reduced levels of herbivore-induced JA and jasmonoyl-isoleucine(JAIle). The oe-JMT plants were more attractive to BPH female adults but showed increased resistance to BPH nymphs,probably owing to the different responses of BPH female adults and nymphs to the changes in levels of H_2O_2 and Me JA in oe-JMT plants. These results indicate that Os JMT1,by altering levels of JA and related metabolites, plays a role in regulating plant development and herbivore-induced defense responses in rice. | Jinfeng Qi Jiancai Li Xiu Han Ran Li Jianqiang Wu Haixin Yu Lingfei Hu Yutao Xiao Jing Lu Yonggen Lou | 2016 | Journal of Integrative Plant Biology2016，58，6： | 10 |
| 3 | First-line pemetrexed-platinum doublet chemotherapy with or without bevacizumab in non-squamous non-small cell lung cancer: A real-world propensity score-matched study in China显示文摘Objective: To evaluate the efficacy and safety profile of first-line bevacizumab(Bev)-containing pemetrexedplatinum chemotherapy in a real-world Chinese cohort with advanced non-squamous non-small cell lung cancer(NS-NSCLC).Methods: A total of 415 eligible patients with NS-NSCLC who received first-line pemetrexed-platinum chemotherapy at National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College between February 2010 and September 2017 were reviewed retrospectively: 309 Bev(-) and 106 Bev(+) cases. Bev was administered at 7.5 mg/kg every 3 weeks in the Bev(+) group. To reduce the risk of a selection bias, a propensity score-matching(PSM) was conducted and 105 pairs of Bev(-) and Bev(+) cases were identified.Results: The median duration of follow-up was 15.8 months. The median progression-free survival(PFS) was prolonged significantly in the Bev(+) group than in the Bev(-) group in overall(9.8 vs. 7.8 months, P=0.006) and PSM pairs(9.8 vs. 6.6 months, P<0.001). Moreover, patients receiving maintenance therapy with pemetrexed plus Bev had longer PFS than those interrupted after induction chemotherapy, or those receiving mono-maintenance with pemetrexed(12.3 vs. 4.8 vs. 8.6 months;P<0.001). Multivariate analyses revealed Bev to be one of the favorable prognostic factors for PFS, along with the predictor of maintenance therapy.Conclusions: First-line induction and maintenance therapy with Bev(7.5 mg/kg every 3 weeks) combined with pemetrexed-platinum chemotherapy was efficacious and superior to non-Bev chemotherapy in Chinese patients with advanced NS-NSCLC. | Fei Qi Xingsheng Hu Yutao Liu Zhijie Wang Jianchun Duan Jie Wang Mei Dong | 2019 | Chinese Journal of Cancer Research2019，31，5： | 4 |
| 4 | MOEA/D with adaptive weight adjustment显示文摘 | QI Yutao MA Xiaoliang LIU Fangi | 2014 | Evolutionary computation2014，22，2： | 1 |
| 5 | α-1-Syntrophin Mutation and the Long-QT Syndrome: A Disease of Sodium Channel Disruption显示文摘 | Geru Wu Tomohiko Ai Jeffrey J. Kim Bhagyalaxmi Mohapatra Yutao Xi Zhaohui Li Shahrzad Abbasi Enkhsaikhan Purevjav Kaveh Samani Michael J. Ackerman Ming Qi Arthur J. Moss Wataru Shimizu Jeffrey A. Towbin Jie Cheng Matteo Vatta | 2008 | Circulation: Arrhythmia and Electrophysiology2008，，3： | 1 |
| 6 | Incorporating multiple SVMs for automatic image annotation显示文摘 | Qi Xiaojun Han Yutao | | 0，，02： | 1 |
| 7 | MOEA/D with adaptive weight adjustment显示文摘 | QI Yutao MA Xiaoliang LIUFang | 2014 | Evolutionary Computation2014，22，2： | 1 |
| 8 | Anovel fusion approach to content-based image retrieval显示文摘 | Xiaojun Qi Yutao Han | 2005 | Pattern Recognition2005，，： | 1 |
| 9 | Multi-Agent Immune Memory Clone Based Multicast Routing显示文摘 | QI Yutao JIAO Licheng LIU Fang | 2008 | Chinese Journal of Electronics2008，17，2： | 1 |
| 10 | Multi -objective immune al- gorithm with Baldwinian learning 显示文摘 | QI YUTAO LIU FANG LI MEIYUN | 2012 | Applied Soft Computing2012，，12： | 1 |
| 11 | Water effect on peroxy radical measurement by chemical amplification: Experimental determination and chemical mechanism显示文摘The water effect on peroxy radical measurement by chemical amplification was determined experimentally for HO2 and HO2+OH, respectively at room temperature (298±2) K and atmospheric pressure (1×105 Pa). No significant difference in water effect was observed with the type of radicals. A theoretical study of the reaction of HO2·H2O adduct with NO was performed using density functional theory at CCSD(T)/6-311 G(2d, 2p)//B3LYP/6-311 G(2d, 2p) level of theory. It was found that the primary reaction channel for the reaction is HO2·H2O+NO→HNO3+H2O (R4a). On the basis of the theoretical study, the rate constant for (R4a) was calculated using Polyrate Version 8.02 program. The fitted Arrenhnius equation for (R4a) is k = 5.49×107 T 1.03exp(?14798/T) between 200 and 2000 K. A chemical model incorporated with (R4a) was used to simulate the water effect. The water effect curve obtained by the model is in accordance with that of the experiment, suggesting that the water effect is probably caused mainly by (R4a). | QI Bin LIU Lu CHAO YuTao WANG ZhuQing YANG HongYan | 2008 | Science China Chemistry2008，51，3： | 1 |
| 12 | Recovery of Four COVID-19 Patients via Ozonated Autohemotherapy显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an enveloped RNA betacoronavirus,1 that has spread globally since December 2019.As of July 22,2020,more than 14,000,000 confirmed cases and 607,781 deaths from COVID-19 have been reported to the World Health Organization from 216 areas and territories.2 Patientswithmore prominent laboratory abnormalities may develop acute respiratory distress syndrome(ARDS),which potentially leads tomultiple organ failure and death.1,3 However,at present,there are no regulatory approved antiviralmedicines,vaccines,or specific clinical treatments for COVID-19. | Junping Wu Cherie S.Tan Hongzhi Yu Youwei Wang Yutao Tian Wenwei Shao Yifei Zhang Kuo Zhang Hongxia Shao Guangjian Ni Jun Shen Antonio Carlo Galoforo Qi Wu Dong Ming | 2020 | The Innovation2020，1，3： | 1 |
| 13 | Multi-objective immune algorithm with Baldwinian learning显示文摘 | QI Yutao LIU Fang GONG Maoguo | 2012 | Applied Soft Computing2012，12，8： | 1 |
| 14 | Adaptive evolution to the natural and anthropogenic environment in a global invasive crop pest,the cotton bollworm显示文摘The cotton bollworm,Helicoverpa armigera,is set to become the most economically devastating crop pest in the world,threatening food security and biosafety as its range expands across the globe.Key to understanding the eco-evolutionary dynamics of H.armigera,and thus its management,is an understanding of population connectivity and the adaptations that allow the pest to establish in unique environments.We assembled a chromosome-scale reference genome and re-sequenced 503 individuals spanning the species range to delineate global patterns of connectivity,uncovering a previously cryptic population structure. | Minghui Jin Henry L.North Yan Peng Hangwei Liu Bo Liu Ruiqing Pan Yan Zhou Weigang Zheng Kaiyu Liu Bo Yang Lei Zhang Qi Xu Samia Elfekih Wendy A.Valencia-Montoya Tom Walsh Peng Cui Yongfeng Zhou Kenneth Wilson Chris Jiggins Kongming Wu Yutao Xiao | 2023 | The Innovation2023，4，4： | 0 |
| 15 | Mechanism and kinetics of the production of hydroxymethyl hydroperoxide in ethene/ozone/water gas-phase system显示文摘The mechanism and kinetics of the production of hydroxymethyl hydroperoxide (HMHP) in ethene/ ozone/water gas-phase system were investigated at room temperature (298±2 K) and atmospheric pressure (1×105 Pa). The reactants were monitored in situ by long path FTIR spectroscopy. Peroxides were measured by an HPLC post-column fluorescence technique after sampling with a cold trap. The rate constants (k3) of reaction CH2O2+H2O→HMHP (R3) determined by fitting model calculations to ex-perimental data range from (1.6―6.0)×10?17 cm3·molecule?1·s?1. Moreover, a theoretical study of reac-tion (R3) was performed using density functional theory at QCISD(T)/6-311+(2d,2p)//B3LYP/6-311+G(2d, 2p) level of theory. Based on the calculation of the reaction potential energy surface and intrinsic reac-tion coordinates, the classic transitional state theory (TST) derived k3 (kTST), canonical variational tran-sition state theory (CVT) derived k3 (kCVT), and the corrected kCVT with small-curvature tunneling (kCVT/SCT) were calculated using Polyrate Version 8.02 program to be 2.47×10-17, 2.47×10-17 and 5.22×10-17 cm3·molecule-1·s-1, respectively, generally in agreement with those fitted by the model. | QI Bin CHAO YuTao CHEN ZhongMing | 2007 | Science China Chemistry2007，50，3： | 0 |
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