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61篇 您的检索式:作者名="QIN HaiYan"
    题名 作者 年代 出处 被引量
1Biodegradation of pendimethalin by Bacillus subtilis Y3显示文摘A bacterium strain Y3,capable of efficiently degrading pendimethalin,was isolated from activated sludge and identified as Bacillus subtilis according to its phenotypic features and 16 S rRNA phylogenetic analysis.This strain could grow on pendimethalin as a sole carbon source and degrade 99.5%of 100 mg/L pendimethalin within 2.5 days in batch liquid culture,demonstrating a greater efficiency than any other reported strains.Three metabolic products,6-aminopendimethalin,5-amino-2-methyl-3-nitroso-4-(pentan-3-ylamino) benzoic acid,and 8-amino-2-ethyl-5-(hydroxymethyl)-1,2-dihydroquinoxaline-6-carboxylic acid,were identified by HPLC-MS/MS,and a new microbial degradation pathway was proposed.A nitroreductase catalyzing nitroreduction of pendimethalin to 6-aminopendimethalin was detected in the cell lysate of strain Y3.The cofactor was nicotinamide adenine dinucleotide phosphate(NADPH) or more preferably nicotinamide adenine dinucleotide(NADH).The optimal temperature and pH for the nitroreductase were 30℃ and 7.5,respectively.Hg^(2+),Ni^(2+),Pb^(2+),Co^(2+),Mn^(2+) Cu^(2+),Ag^+,and EDTA severely inhibited the nitroreductase activity,whereas Fe^(2+),Mg^(2+),and Ca^(2+) enhanced it.This study provides an efficient pendimethalin-degrading microorganism and broadens the knowledge of the microbial degradation pathway of pendimethalin.Haiyan Ni Li Yao Na Li Qin Cao Chen Dai Jun Zhang Qin He Jian He 2016Journal of Environmental Sciences2016,28,3:7
2A hybrid LES (Large Eddy Simulation)/assumed sub-grid PDF (Probability Density Function) model for supersonic turbulent combustion显示文摘A hybrid LES (Large Eddy Simulation)/assumed sub-grid PDF (Probability Density Function) closure model has been devel-oped for supersonic turbulent combustion. Scalar transport equations for all species in a given chemical kinetic mechanism were solved, which are necessary in the supersonic combustion where the non-equilibrium chemistry is essentially involved. The clipped Gaussian PDF of temperature and multivariate ? PDF of composition were used to close the sub-grid chemical sources that appear in the conservation equations. The sub-grid variances of temperature and composition were constructed based on scale similarity approach. A semi-implicit approach based on the PDF model was proposed to tackle the resulting numerical stiffness associated with finite rate chemistry. The model was applied to simulate a supersonic, coaxial H2-air burner, where both the mean and rms (root mean square) results were compared with the experimental data. In general, good agree-ments were achieved, which indicated that the present sub-grid PDF method could work well in simulating supersonic turbu-lent combustion. Moreover, the calculation showed that the sub-grid fluctuations of temperature and major species in the combustion region were of the order of 10%-20% of their rms, while the sub-grid fluctuation of hydroxyl might be as high as 40%-50% of its rms.WANG HongBo QIN Ning SUN MingBo WU HaiYan WANG ZhenGuo 2011Science China(Technological Sciences)2011,54,10:6
3Pertuzumab in combination with trastuzumab and chemotherapy for Chinese patients with HER2-positive metastatic gastric or gastroesophageal junction cancer:a subpopulation analysis of the JACOB trial显示文摘Background:The JACOB trial(NCT01774786)was a double-blinded,placebo-controlled,randomized,multicenter,international,phase III trial evaluating the efficacy and safety of adding pertuzumab to trastuzumab and chemo-therapy in first-line treatment of human epidermal growth factor receptor 2(HER2)-positive metastatic gastric cancer/gastroesophageal junction cancer(GEJC).The aim of this analysis was to investigate efficacy and safety outcomes in the Chinese subpopulation from the JACOB trial.Methods:This post hoc subpopulation analysis included all patients recruited in China's Mainland(n=163;20.9%)between June 2013 and January 2016.The patients were randomly assigned in a 1:1 ratio to receive pertuzumab plus trastuzumab and chemotherapy(pertuzumab group;n=82)or placebo plus trastuzumab and chemotherapy(con-trol group;n=81).Intravenous pertuzumab(840 mg)and trastuzumab(8 mg/kg loading and 6 mg/kg maintenance doses)were given every 3 weeks until disease progression or unacceptable toxicity.Chemotherapy was given as per standard regimens/doses of capecitabine or 5-fluorouracil plus cisplatin.The primary endpoint was overall survival(OS);secondary efficacy endpoints included progression-free survival(PFS),and overall objective response rate(ORR).Results:The median OS was 18.7 months in the pertuzumab group and 16.1 months in the control group(hazard ratio[HR]0.75;95%confidence interval[CI]0.49 to 1.14).The median PFS was 10.5 and 8.6 months in the pertuzumab and control groups,respectively(HR 0.85;95%CI 0.60 to 1.21),and the median ORRs were 68.9%and 55.7%,respectively.The treatment effect in this Chinese subpopulation showed consistency with that in the global ITT population with numerically lower HR for OS and PFS compared with the control group.The safety profiles of the pertuzumab and control groups in this Chinese subpopulation analysis were generally comparable.The most common grade 3-5adverse events were neutropenia,anemia,and leukopenia.However,due to the nature of being a post hoc subgroup analysis,the results presented here are descriptive only and need to be interpreted with caution.Conclusions:OS and PFS were numerically improved by adding pertuzumab to trastuzumab and chemotherapy as first-line treatment in Chinese HER2-positive gastric cancer/GEJC patients,and this regimen demonstrated an acceptable safety profile.Tianshu Liu Yanru Qin Jin Li Ruihua Xu Jianming Xu Shujun Yang Shukui Qin Yuxian Bai Changping Wu Yixiang Mao Haiyan Wu Yilin Ge Lin Shen 2019Cancer Communications2019,39,1:6
4The fluidity and molding ability of glass-forming Zr-based alloy melt显示文摘The fluidity and filling ability of glass-forming Zr-based alloy melt in copper mould were investigated both theoretically and experimentally. The major factors which affected the flowing behavior of the metallic melt in the mold were determined,which provides the foundation for overcoming the contradiction between the filling and formation of amorphous alloy during the rapid cooling process of the metallic melts. The casting factors to prepare a metallic ring were discussed and selected. As a result,a Zr-based bulk metallic glass ring was prepared successfully.MA MingZhen ZONG HaiTao WANG HaiYan QI YanPeng LIANG SunXing SONG AiJun ZHANG WeiGuo WANG Qiang ZHANG XinYu JING Qin LI Gong LIU RiPing 2008Science China(Physics,Mechanics & Astronomy)2008,51,4:6
5Synergistic graphene/aluminum surface plasmon coupling for zinc oxide lasing improvement显示文摘免费电子的集体摆动在材料的表面上产生电浆子。耳语画廊 microcavity 有效地从它的内部墙基于全部的思考在它的表面上限制轻地。当这些二种电磁波遇见对方时,多于在耳语画廊 microcavity 与 graphene 和艾尔 nanoparticles 的单层是涂的以后, 50 褶层和阀值被减少,从单个 ZnO microrod 的刺激排出物被提高。放射激光的表演的改进被归因于与 ZnO 激子 graphene/Al 表面电浆子联合的 synergistic 精力。放射激光的特征和联合机制系统地被调查。Qiuxiang Zhu Feifei Qin Junfeng Lu Zhu Zhu Haiyan Nan Zengliang Shi Zhenhua Ni Chunxiang Xu 2017Nano Research2017,10,6:6
6Surface and intrinsic contributions to extinction properties of ZnSe quantum dots显示文摘This work studies extinction properties of ZnSe quantum dots terminated with either Se-surface or Zn-surface(Se-ZnSe or Zn-ZnSe QDs).In addition to commonly observed photoluminescence quenching by anionic surface sites,Se-ZnSe QDs are found to show drastic signatures of Se-surface states in their UV-visible(Vis)absorption spectra.Similar to most QDs reported in literature,monodisperse Zn-ZnSe QDs show sharp absorption features and blue-shifted yet steep absorption edge respect to the bulk bandgap.However,for monodisperse Se-ZnSe QDs,all absorption features are smeared and a low-energy tail is identified to extend to an energy window below the bulk ZnSe bandgap.Along increasing their size,a cyclic growth of ZnSe QDs switches their surface from Zn-terminated to Se-terminated ones,which confirms that the specific absorption signatures are reproducibly repeated between those of two types of the QDs.Though the extinction coefficients per unit of Se-ZnSe QDs are always larger than those of Zn-ZnSe QDs with the same size,both of them approach the same bulk limit.In addition to contribution of the lattice,extinction coefficients per nanocrystal of Zn-ZnSe QDs show an exponential term against their sizes,which is expected for quantum-confinement enhancement of electron-hole wavefunction overlapping.For Se-ZnSe QDs,there is the third term identified for their extinction coefficients per nanocrystal,which is proportional to the square of size of the QDs and consistent with surface contribution.Shangxin Lin Jiongzhao Li Chaodan Pu Hairui Lei Meiyi Zhu Haiyan Qin Xiaogang Peng 2020Nano Research2020,13,3:5
7Characterization of T.aestivum-H.californicum chromosome addition lines DA2H and MA5H显示文摘In order to transfer useful genes of Hordeum californicum into common wheat(Triticum aestivum L.),the T.aestivum c.v.Chinese Spring(CS)-H.californicum amphiploid was crossed to CS,and its backcrossing and self-fertilized progenies were analyzed by morphological observation,cytological,biochemical and molecular marker techniques.Alien addition lines with two H.californicum chromosomes were identified and their genetic constitution was characterized.STS-PCR analysis using chromosome 2B specific markers indicated that chromosome H3 of H.californicum belongs to homoeologous group 2,and was thus designated 2H.SDS-PAGE showed that chromosome H2 of H.californicum belongs to homoeologous group 5,and was designated 5H.The CS-H.californicum amphiploid and the chromosome addition lines(DA2H and MA5H) identified were evaluated for powdery mildew(Erysiphe graminis f.sp.triticii) resistance in field.The preliminary results indicated that the amphiploid showed higher powdery mildew resistance than CS.However,chromosome addition lines DA2H and MA5H were highly susceptible to powdery mildew,indicating that major powdery mildew resistant genes of H.californicum should be located on chromosomes other than 2H and 5H.Fang Kong Haiyan Wang Aizhong Cao Bi Qin Jianhui Ji Suling Wang Xiu-E Wang 2008Journal of Genetics and Genomics2008,35,11:5
8GmCRY1s modulate gibberellin metabolism to regulate soybean shade avoidance in response to reduced blue light显示文摘Soybean is an important legume crop that displays the classic shade avoidance syndrome(SAS),including exaggerated stem elongation,which leads to lodging and yield reduction under density farming conditions.Here,we compared the effects of two shade signals,low red light to far-red light ratio(R:FR)and low blue light(LBL),on soybean status and revealed that LBL predominantly induces excessive stem elongation.We used CRISPR-Cas9-engineered Gmcry mutants to investigate the functions of seven cryptochromes(GmCRYs)in soybean and found that the four GmCRY1s overlap in mediating LBL-induced SAS.Lightactivated GmCRY1s increase the abundance of the bZlP transcription factors STF1 and STF2,which directly upregulate the expression of genes encoding GA2 oxidases to deactivate GA1 and repress stem elongation.Notably,GmCRY1b overexpression lines displayed multiple agronomic advantages over the wild-type control under both dense planting and intercropping conditions.Our study demonstrates the integration of GmCRY1-mediated signals with the GA metabolic pathway in the regulation of LBL-induced SAS in soybean.It also provides a promising option for breeding lodging-resistant,high-yield soybean cultivars in the future.Xiangguang Lyu Qican Cheng Chao Qin Yinghui Li Xinying Xu Ronghuan Ji Ruolan Mu Hongyu Li Tao Zhao Jun Liu Yonggang Zhou Haiyan Li Guodong Yang Qingshan Chen Bin Liu 2021Molecular Plant2021,14,2:4
9Tangnaikang improves insulin resistance and β-cell apoptosis by ameliorating metabolic inflammation in SHR.Cg-Lepr^(cp)/NDmcr rats显示文摘OBJECTIVE: To investigate the effects of Tangnaikang(TNK), a mixture of five herbal plant extracts,on inflammation-mediated insulin resistance andβ-cell apoptosis in SHR.Cg-Leprcp/NDmcr(SHR-cp)rats.METHODS: Seven-week-old SHR-cp rats were randomly divided into a control(CON) group and a TNK(3.24 g/kg) group. Wistar-Kyoto rats at the same age were used as the normal control group.After 7 weeks of continuous intragastric administration of TNK, the glucose metabolic status and insulin sensitivity of the rats were evaluated by assessing fasting serum glucose(FBG), the oral glucose tolerance test(OGTT), fasting serum insulin(FINS),and the insulin sensitivity index(ISI). Serum tumor necrosis factor-α(TNF-α), interleukin-6(IL-6), C-reactive protein(CRP) and adiponectin were measured via enzyme-linked immunosorbent assays.Macrophage infiltration and apoptosis in adipose tissues were detected through F4/80 immunohistochemistry and the terminal deoxynucleotidyl transferase d UTP nick end labeling(TUNEL) assay. Islet morphology and β-cell apoptosis were investigated using double immunofluorescence staining and the TUNEL assay. The expression of cytokine genes in adipose tissue, the liver, and the pancreas was detected in real-time polymerase chain reaction assays. The expression and phosphorylation levels of insulin signaling-, inflammation-, and β-cell survival-related proteins in the liver and pancreas of SHR-cp rats were detected by western blotting.RESULTS: TNK(3.24 g/kg) treatment significantly decreased body weight, FBG and FINS; improved impaired glucose tolerance; increased the ISI; reduced serum levels of TNF-α, CRP and IL-6; and increased serum adiponectin. The m RNA expression of inflammatory markers was markedly reduced in the liver, pancreas, and adipose tissue. F4/80-and TUNEL-positive cells in adipose tissues were decreased, as was the number of TUNEL-positiveβ-cells. The phosphorylation of c-Jun N-terminal kinase and that of insulin receptor substrate-1 at serines 307 and 1101 was significantly decreased.In the pancreas, the expression of nuclear factor kappa-light chain-enhancer of activated B cells-p65 was significantly decreased, and phosphoinositide3-kinase and IRS-2 were significantly increased.CONCLUSION: TNK was able to improve insulin resistance and β-cell apoptosis in SHR-cp rats, which might be associated with its ability to relieve the overall and local metabolic inflammatory responses observed in SHR-cp rats.Li Linyi Hisae Yoshitomi Qin Lingling Wu Xinli Zhou Tian Wang Haiyan Jiang Yueying Wei Ying Xu Tunhai Liu Tonghua Gao Ming 2017Journal of Traditional Chinese Medicine2017,37,3:3
10Synthesis of Nano-ZSM-5 in Ultra-Concentrated System and Its Performance in Diesel Hydrodewaxing显示文摘Nanocrystalline ZSM-5(with a crystal size in the range of 20—30 nm) has been synthesized in only 20 h via the crystallization of ultra-concentrated homogeneous synthesis mixtures. The influence of low water content, use of compound surfactant, a proper crystallization time and SiO_2/Al_2O_3 molar ratio on the properties of the final nanocrystalline ZSM-5 has been studied. Especially, the use of compound surfactant has influenced some properties of nano-ZSM such as the morphology, crystal size and crystallization greatly. The nano-ZSM-5 zeolite was investigated using XRD, BET, SEM, NH_3-TPD, and other techniques. The evaluation results in a 200-mL hydrogenation unit indicated that the synthesized nano-ZSM-5 had excellent catalytic performance in diesel hydrodewaxing.Qin Lihong Li Haiyan Li Jun Sun Famin 2016China Petroleum Processing & Petrochemical Technology2016,18,4:3
11Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization显示文摘NF-κB, a family of transcription factors regulating diverse biological processes including immune responses, is activated by canonical and noncanonical pathways based on degradation of IκBα and processing of the IκB-like protein p100, respectively. Although p100 responds to noncanonical NF-κB stimuli for processing, it does not undergo degradation, but rather becomes accumulated, along with canonical NF-κB activation. We show here that the stability of p100 is tightly controlled by a deubiquitinase, Otub1. Otub1 deficiency not only promotes signal-induced p100 processing and noncanonical NF-κB activation but also causes steady-state p100 degradation, leading to aberrant NF-κB activation in the canonical pathway. B-cell-conditional deletion of Otub1 results in B-cell hyperplasia, antibody hyper-production, and lupus-like autoimmunity. Otub1-deficient B cells display aberrantly activated phenotypes and overproduce the cytokine IL-6, contributing to autoimmunity induction. Thus, maintenance of p100 stability by Otub1 serves as an unusual mechanism of NF-κB regulation that prevents autoimmunity.Yanchuan Li Jin-Young Yang Xiaoping Xie Zuliang Jie Lingyun Zhang Jianhong Shi Daniel Lin Meidi Gu Xiaofei Zhou Haiyan S. Li Stephanie S. Watowich Antrix Jain Sung Yun Jung Jun Qin Xuhong Cheng Shao-Cong Sun 2019Cell Research2019,29,6:3
12Mass loss and nutrient dynamics during litter decomposition in response to warming and nitrogen addition in a desert steppe显示文摘Plant litter decomposition has been studied extensively in the context of both warming and increased atmospheric nitrogen deposition. However, the temporal patterns of mass loss and nutrient release in response to warming and nitrogen addition remain unclear. A 2-year decomposition experiment aimed to examine the effects of warming and nitrogen addition on decomposition rate, and nitrogen and phosphorus dynamics. The effects of warming and nitrogen addition on decomposition of litter of Stipa breviflora, a dominant species in a desert steppe of northern China, were studied. Warming and nitrogen addition significantly enhanced litter mass loss by 10% and 16%, respectively, and moreover promoted nitrogen and phosphorus release from the litter in the first year of decomposition, followed by an immobilization period. The interactive effects of warming and nitrogen addition on mass loss, nitrogen and phosphorus concentrations of litter were also found during the decomposition. This study indicates that warming and nitrogen addition increased litter mass loss through altering litter quality. These findings highlight that interactions between climate change and other global change factors could be highly important in driving decomposition responses.Haiyan REN Jie QIN Baolong YAN Alata Baoyinhexige Guodong HAN 2018Frontiers of Agricultural Science and Engineering2018,5,1:3
13One-pot/three-step synthesis of zinc-blende CdSe/CdS core/shell nanocrystals with thick shells显示文摘A one-pot/three-step synthetic scheme was developed for phase-pure epitaxy of CdS shells on zinc-blende CdSe nanocrystals to yield shells with up to sixteen monolayers. The key parameters for the epitaxy were identified, including the core nanocrystal concentration, solvent type/composition, quality of the core nanocrystals, epitaxial growth temperature, type/concentration of ligands, and composition of the precursors. Most of these key parameters were not influential when the synthetic goal was thin-shell CdSe/CdS core/shell nanocrystals. The finalized synthetic scheme was reproducible at an almost quantitative level in terms of the crystal structure, shell thickness, and optical properties.Yuan Niu Chaodan Pu Runchen Lai Renyang Meng Wanzhen Lin Haiyan Qin Xiaogang Peng 2017Nano Research2017,10,4:3
14Optimization of Cutting Parameters in Helical Milling of Carbon Fiber Reinforced Polymer显示文摘To investigate cutting performance in the helical milling of carbon fiber reinforced polymer(CFRP),experiments were conducted with unidirectional laminates.The results show that the influence of cutting parameters is very significant in the helical milling process. The axial force increases with the increase of cutting speed, which is below 95 m/min; otherwise, the axial force decreases with the increase of cutting speed. The resultant force always increases when cutting speed increases; with the increase of tangential and axial feed rates, cutting forces increase gradually. In addition, damage rings can appear in certain regions of the entry edges; therefore, the relationship between machining performance(cutting forces and holemaking quality) and cutting parameters is established using the nonlinear fitting methodology. Thus, three cutting parameters in the helical milling of CFRP, under the steady state, are optimized based on the multi-objective genetic algorithm, including material removal rate and machining performance. Finally, experiments were carried out to prove the validity of optimized cutting parameters.Haiyan Wang Xuda Qin Dongxu Wu Aijuan Song 2018Transactions of Tianjin University2018,24,1:3
15Organosulfur compounds induce cytoprotective autophagy against apoptosis by inhibiting mTOR phosphorylation activity in macrophages显示文摘Organosulfur compounds (OSCs)are the bioactive components of garlic.Some OSCs have apoptotic or autophagy-inducing effects.Autophagy plays roles in both cytoprotection and apoptosis-related cell death,and the interaction between autophagy and apoptosis is important in the modulation of immune responses.The mechanism of an OSC-mediated effect via the interaction of autophagy and apoptosis is unknown.In this study,the effects of five OSC compounds on autophagy in the macrophage cell line RAW264.7 and primary macrophages were investigated.We found that S-allylcysteine (SAC),diallyl disulde (DADS)and diallyl tetrasulfide (DTS)treatment increased the number of autophagosomes of RAW264.7 cells,inhibited the phosphorylation of ribosomal protein S6 kinase beta-1 (p70S6K/S6K1)which is a substrate of mammalian target of rapamycin (roTOR),and significantly enhanced autophagy flux.The induction of autophagy by SAC,DADS and DTS was inhibited by stably knocking down the expression of autophagy-related gene 5 (ATG5)with short hairpin RNA (shRNA).Further experiments confirmed that SAC,DADS and DTS also induced apoptosis in RAW264.7 cells.The induction of apoptosis and Caspase 3 activity by SAC,DADS and DTS were increased by stably knocking down of ATG5 expression with shRNA in RAW264.7 cells or treating with 5 mM 3-MA in primary macrophages.Our results suggest that SAC,DADS and DTS induce both autophagy and apoptosis.The autophagy induction protects macrophages from apoptosis by inhibiting mTOR phosphorylation activity to maintain the mass of immune cells.Yanyang Wu Yongquan Hu Haiyan Zhou Jiayu Zhu Zhongyi Tong Si Qin Dongbo Liu 2018Acta Biochimica et Biophysica Sinica2018,50,11:2
16The Effect of Surfactant on Synthesis of ZSM-5 in a Super-Concentrated System显示文摘ZSM-5 zeolite was synthesized in a super-concentrated system using different kinds of surfactants. The ZSM-5 samples were characterized by XRD, SEM, FT-IR and BET techniques. The surfactant could change the properties of ZSM-5 zeolite, including the crystallinity, the crystal grain size, the surface area, the pore volume and the Si/Al mole ratio.Li Haiyan Qin Lihong Gao Guangbo Sun Famin 2016China Petroleum Processing & Petrochemical Technology2016,18,3:2
17A wet adhesion inspired biomimetic pad with direction dependence and adaptability显示文摘A novel adhesive pad for a climbing robot, inspired by a stick insect's smooth pad, is proposed. The micro structure pattern and inclined fiber of a stick insect's pad are mimicked, and an adhesion force is produced based on its wet adhesion mechanism. Firstly, the wet adhesion model is discussed and the pad is designed; secondly, the adhesion characteristics, adhesion direction dependence and adaptability are analyzed; finally, the proposed pad is fabricated using a thermoplastic elastomer, which is a hydrophilic and viscoelastic material. Experimental results show that the adhesion performance of the pad is good, and normal adhesion and friction can reach to 0.65 N and 3 N. Furthermore, the adhesion of the pad is direction dependent and self-adaptive.LI MingHe HE Bin QIN HaiYan ZHOU YanMin LU HanXiong YUE JiGuang 2011Chinese Science Bulletin2011,56,18:2
18Primary dendrite growth of Ni_3Sn intermetallic compound during rapid solidification of undercooled Ni-Sn-Ge alloy显示文摘Liquid Ni-31.7%Sn-2.5%Ge alloy was highly undercooled by up to 238 K(0.17TL) with glass fluxing and drop tube techniques.The dendritic growth velocity of primary Ni3Sn compound shows a power-law relation to undercooling and achieves a maximum velocity of 380 mm/s.The addition of Ge reduces its growth velocity as compared with the binary Ni75Sn25 alloy.A structural transition from coarse dendrites into equiaxed grains occurs once undercooling exceeds a critical value of about 125 K,which is accompanied by both grain refinement and solute trapping.The Ni3Sn intermetallic compound behaves like a normal solid solution phase showing nonfaceted growth during rapid solidification.WANG WeiLi QIN HaiYan XIA ZhenChao WEI BingBo 2012Chinese Science Bulletin2012,57,9:2
19Prediction of cutting forces in helical milling process显示文摘Haiyan Wang Xuda Qin Chengzu Ren Qi Wang 2012The International Journal of Advanced Manufacturing Technology2012,,9:2
20Epigenetic silencing of WIF - 1 in hepatocellular carcinomas显示文摘Yun Deng Bin Yu Qin Cheng Jie Jin Haiyan You Ronghu Ke Ning Tang Qiujin Shen Huiqun Shu Genfu Yao Zhigang Zhang Wenxin Qin 2010Journal of Cancer Research and Clinical Oncology2010,,8:1
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