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| 1 | Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup analysis of a randomized phase 2 study (ALTER1202)显示文摘Patients with small-cell lung cancer (SCLC) relapse within months after completing previous therapies. This study aimed to investigate the efficacy and safety of anlotinib as third- or further-line therapy in patients with short-term relapsed SCLC from ALTER1202. Patients with short-term relapsed SCLC (disease progression within 3 months after completing ≥ two lines of chemotherapy) in the anlotinib (n = 67) and placebo (n = 34) groups were analyzed. The primary endpoint was progression-free survival (PFS). The secondary endpoints included overall survival, objective response rate (ORR), disease control rate, and safety. Anlotinib significantly improved median PFS/OS (4.0 vs. 0.7 months, P < 0.0001)/(7.3 vs. 4.4 months, P = 0.006) compared with placebo. The ORR was 4.5%/2.9% in the anlotinib/placebo group (P = 1.000). The DCR in the anlotinib group was higher than that in the placebo group (73.1% vs. 11.8%, P < 0.001). The most common adverse events (AEs) were hypertension (38.8%), loss of appetite (28.4%), and fatigue (22.4%) in the anlotinib group and gamma-glutamyl transpeptidase elevation (20.6%) in the placebo group. No grade 5 AEs occurred. For patients with short-term relapsed SCLC, third- or further-line anlotinib treatment was associated with improved survival benefit. Further studies are warranted in this regard. | Jianhua Shi Ying Cheng Qiming Wang Kai Li Lin Wu Baohui Han Gongyan Chen Jianxing He Jie Wang Haifeng Qin Xiaoling Li | 2022 | Frontiers of Medicine2022，16，5： | 5 |
| 2 | Progress of power field effect transistor based on ultra-wide bandgap Ga_2O_3 semiconductor material显示文摘As a promising ultra-wide bandgap semiconductor, gallium oxide(Ga_2O_3) has attracted increasing attention in recent years. The high theoretical breakdown electrical field(8 MV/cm), ultra-wide bandgap(~ 4.8 eV) and large Baliga's figure of merit(BFOM) of Ga_2O_3 make it a potential candidate material for next generation high-power electronics, including diode and field effect transistor(FET). In this paper, we introduce the basic physical properties of Ga_2O_3 single crystal, and review the recent research process of Ga_2O_3 based field effect transistors. Furthermore, various structures of FETs have been summarized and compared, and the potential of Ga_2O_3 is preliminary revealed. Finally, the prospect of the Ga_2O_3 based FET for power electronics application is analyzed. | Hang Dong Huiwen Xue Qiming He Yuan Qin Guangzhong Jian Shibing Long Ming Liu | 2019 | Journal of Semiconductors2019，40，1： | 4 |
| 3 | Complex conforming Delaunay triangulation显示文摘A novel algorithm of conforming Delaunay triangulation for curved geometry is presented in the paper.A progress has been made for the problem puzzled Delaunay refinement where curved constraints cannot be accepted as input directly.The algorithm is based on a new sufficient condition for the existence of constraints in triangulation.It requires computing only the intersection between constraints and Voronoi edges or faces instead of the circum-sphere of curved constraint.For the termination of the algorithm when small input angles exist in constraints, a weighted method is applied to ensure that the algorithm can terminate under any input.Some two-dimensional and three-dimensional results are also presented.It is shown that the algorithm has the capability of dealing with both linear and nonlinear constraints in a consistent way, without the need of maintaining triangular meshes on face constraints. | MENG XianHai LI JiGang YANG Qin CAI Qiang CHEN QiMing | 2010 | Science China(Information Sciences)2010，53，6： | 3 |
| 4 | Definitions of Natural-Language Spatial Relations: Combining Topology and Directions显示文摘Because SQL for querying data from spatial databa se s is ineffective, the query based on natural or visual language becomes an attra ctive research field gradually. However, how to define and represent natural lan guages related to spatial data are still gigantic problems. Because existing mod els of direction relations can’t describe by use of some common concepts. First of all, detailed direction relations are proposed to describe the directions re lated to the interior of spatial objects, such as 'east part of a region','ea st boundary of a region', and so on. Secondly, by integrating the detailed dire ctions with exterior direction relations and topological relations, several NLSR s are defined, such as 'a road goes across the east part of a lake', 'a river goes along the east boundary of a province', etc. Finally, based on the NLSRs abovementioned, a natural spatial query language (NSQL) is formed to retrieve da ta from spatial databases. | DU Shihong WANG Qiao QIN Qiming | 2006 | Geo-Spatial Information Science2006，9，1： | 2 |
| 5 | A Novel Dynamic Stretching Solution to Eliminate Saturation Effect in NDVI and Its Application in Drought Monitoring显示文摘The normalized difference vegetation index(NDVI) is one of the key input variables for developing drought indices.However,the NDVI quickly saturates in high vegetation surfaces,and thus,the generalization of a drought index over different ecosystems becomes a challenge.This paper presents a novel,dynamic stretching algorithm to overcome the saturation effect in NDVI.A scaling transformation function to eliminate saturation effects when the vegetation fraction(VF) is large is proposed.Dynamic range adjustment is conducted using three coefficients,namely,the normalization factor(a),the stretching range controlling factor(m),and the stretching size controlling factor(e).The results show that the stretched NDVI(S-NDVI) is more sensitive to vegetation fraction than NDVI when the VF is large,ranging from 0.75 to 1.00.Moreover,the saturation effect in NDVI is effectively removed by using the S-NDVI.Further analysis suggests that there is a good linear correlation between the S-NDVI and the leaf area index(LAI).At the same time,the proposed S-NDVI significantly reduces or even eliminates the saturation effect over high biomass.A comparative analysis is performed between drought indices derived from NDVI and S-NDVI,respectively.In the experiment,reflectance data from the moderate resolution imaging spectroradiometer(MODIS) products and in-situ observation data from the meteorological sites at a regional scale are used.In this study,the coefficient of determination(R2) of the stretched drought index(S-DI) is above 0.5,indicating the reliability of the proposed algorithm with surface soil moisture content.Thus,the S-DI is suggested to be used as a drought index in extended regions,thus regional heterogeneity should be taken into account when applying stretching method. | LIU Fang QIN Qiming ZHAN Zhiming | 2012 | Chinese Geographical Science2012，22，6： | 2 |
| 6 | Modified perpendicular drought index (MPDI): a real-time drought monitoring method显示文摘 | Abduwasit Ghulam Qiming Qin Tashpolat Teyip Zhao-Liang Li | 2007 | ISPRS Journal of Photogrammetry and Remote Sensing2007，，2： | 2 |
| 7 | Designing of the perpendicular drought index 显示文摘 | GHULAM ABDUWASIT QIN QIMING ZHAN ZHIMING | 2007 | Environmental Geology2007，52，6： | 1 |
| 8 | Designing of the perpendicular drought index显示文摘 | Abduwasit Ghulam Qiming Qin Zhiming Zhan | 2007 | Environmental Geology2007，，6： | 1 |
| 9 | Does the Market Incorporate Previous IPO Withdrawals When Pricing Second--Time IPOs显示文摘 | Qin Lian Qiming Wang | 2009 | Financial Management2009，，： | 1 |
| 10 | Designing of the perpendicular drought index显示文摘 | Abduwasit Ghulam Qin Qiming Zhan Zhiming | 2007 | Environmental Geology2007，52，6： | 1 |
| 11 | Integrated Use of Spatial and Semantic Relationships for Ex- tracting Road Networks from Floating Car Data显示文摘 | Li Jun Qin Qiming Xie Chao | 2012 | International Journal of Applied Earth Observation and Geoinformation2012，19，： | 1 |
| 12 | Designingof the Perpendicular Drought Index 显示文摘 | Ghulam A Qin Qiming Zhan Zhiming | 2007 | Environmental Geology2007，，52： | 1 |
| 13 | Modified Perpen- dicular Drought Index(MPDI) :A Real time Drought Mo-nitoring Method显示文摘 | Ghulam A Qin Qiming Teyip T | 2007 | Journal of Photogrammetry & Remote Sensing2007，，62： | 1 |
| 14 | Designing of the perpendicular drought index显示文摘 | Abduwasit Ghulam Qiming Qin Zhiming Zhan | 2007 | Environmental Geology2007，，6： | 1 |
| 15 | Designing of the Perpendicular Drought Index显示文摘 | Ghulam A Qin Qiming Zhan Zhiming | 2007 | Environ- mental Geology2007，52，： | 1 |
| 16 | Modified Perpendicular Drought Index(MPDI) : A Real-time Drought Monitoring Method显示文摘 | Ghulam A Qin Qiming Teyip T | 2007 | Journal of Photo- grammetry & Remote Sensing2007，62，： | 1 |
| 17 | MODIS -driven estimation of terrestrial latent heat flux in China based on a modified Priestley–Taylor algorithm显示文摘 | Yunjun Yao Shunlin Liang Jie Cheng Shaomin Liu Joshua B. Fisher Xudong Zhang Kun Jia Xiang Zhao Qiming Qin Bin Zhao Shijie Han Guangsheng Zhou Guoyi Zhou Yuelin Li Shaohua Zhao | 2012 | Agricultural and Forest Meteorology2012，，： | 1 |
| 18 | Designing of the Perpendicular Drought Index显示文摘 | Abduwasit Ghulam Qiming Qin Zhiming Zhan | | 0，，06： | 1 |
| 19 | Modified Perpendicular Drought Index (MPDI): A Real-time Drought Monitoring Method显示文摘 | Abduwasit Ghulam Qin Qiming | 2007 | ISPRS Journal of Photogrammetry and Remote Sensing2007，62，： | 1 |
| 20 | Designing of the perpendicular drought index显示文摘 | Ghulam Abduwasit Qin Qiming Zhan Zhiming | 2007 | Environmental Geology2007，52，6： | 1 |
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