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| 1 | Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome显示文摘Regulatory T(Treg) cells, a subtype of immunosuppressive CD4^+T cells, are vital for maintaining immune homeostasis in healthy people. Forkhead box protein P3(FOXP3), a member of the forkhead-wingedhelix family, is the pivotal transcriptional factor of Treg cells. The expression, post-translational modifications, and protein complex of FOXP3 present a great impact on the functional stability and immune plasticity of Treg cells in vivo. In particular, the mutation of FOXP3 can result in immune dysregulation,polyendocrinopathy, enteropathy, X-linked(IPEX) syndrome, which is a rare genetic disease mostly diagnosed in early childhood and can soon be fatal. IPEX syndrome is related to several manifestations,including dermatitis, enteropathy, type 1 diabetes, thyroiditis, and so on. Here, we summarize some recent findings on FOXP3 regulation and Treg cell function. We also review the current knowledge about the underlying mechanism of FOXP3 mutant-induced IPEX syndrome and some latest clinical prospects.At last, this review offers a novel insight into the role played by the FOXP3 complex in potential therapeutic applications in IPEX syndrome. | Qianru Huang Xu Liu Yujia Zhang Jingyao Huang Dan Li Bin Li | 2020 | Journal of Genetics and Genomics2020,47,1: | 8 |
| 2 | Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis显示文摘Curcumenol,an effective ingredient of Wenyujin,has been reported that exerted its antitumor potential in a few cancer types.However,the effect and molecular mechanism of curcumenol in lung cancer are largely unknown.Here,we found that curcumenol induced cell death and suppressed cell proliferation in lung cancer cells.Next,we demonstrated that ferroptosis was the predominant method that contributed to curcumenol-induced cell death of lung cancer in vitro and vivo for the first time.Subsequently,using RNA sequencing,we found that the long non-coding RNA H19(lncRNA H19)was significantly downregulated in lung cancer cells treated with curcumenol,when compared to untreated controls.Overexpression of lncRNA H19 eliminated the anticancer effect of curcumenol,while lncRNA H19 knockdown promoted ferroptosis induced by curcumenol treatment.Mechanistically,we showed that lncRNA H19 functioned as a competing endogenous RNA to bind to miR-19b-3p,thereby enhanced the transcription activity of its endogenous target,ferritin heavy chain 1(FTH1),a marker of ferroptosis.In conclusion,our data show that the natural product curcumenol exerted its antitumor effects on lung cancer by triggering ferroptosis,and the lncRNA H19/miR-19b-3p/FTH1 axis plays an essential role in curcumenol-induced ferroptotic cell death.Therefore,our findings will hopefully provide a valuable drug for treating lung cancer patients. | Ruonan Zhang Ting Pan Yu Xiang Mingming Zhang Han Xie Zimao Liang Bi Chen Cong Xu Jing Wang Xingxing Huang Qianru Zhu Ziming Zhao Quan Gao Chengyong Wen Wencheng Liu Weirui Ma Jiao Feng Xueni Sun Ting Duan Elaine Lai-Han Leung Tian Xie Qibiao Wu Xinbing Sui | 2022 | Bioactive Materials2022,7,7: | 8 |
| 3 | Dendrite‐free lithium and sodium metal anodes with deep plating/stripping properties for lithium and sodium batteries显示文摘Although lithium(Li)and sodium(Na)metals can be selected as the promising anode materials for next‐generation rechargeable batteries of high energy density,their practical applications are greatly restricted by the uncontrollable dendrite growth.Herein,a platinum(Pt)–copper(Cu)alloycoated Cu foam(Pt–Cu foam)is prepared and then used as the substrate for Li and Na metal anodes.Owing to the ultrarough morphology with a threedimensional porous structure and the quite large surface area as well as lithiophilicity and sodiophilicity,both Li and Na dendrite growths are significantly suppressed on the substrate.Moreover,during Li plating,the lithiated Pt atoms can dissolve into Li phase,leaving a lot of microsized holes on the substrate.During Na plating,although the sodiated Pt atoms cannot dissolve into Na phase,the sodiation of Pt atoms elevates many microsized blocks above the current collector.Either the holes or the voids on the surface of Pt–Cu foam what can be extra place for deposited alkali metal,what effectively relaxes the internal stress caused by the volume exchange during Li and Na plating/stripping.Therefore,the symmetric batteries of Li@Pt–Cu foam and Na@Pt–Cu foam have both achieved long‐term cycling stability even at ultrahigh areal capacity at 20 mAh cm−2. | Jianyi Wang Qi Kang Jingchao Yuan Qianru Fu Chunhua Chen Zibo Zhai Yang Liu Wei Yan Aijun Li Jiujun Zhang | 2021 | Carbon Energy2021,3,1: | 6 |
| 4 | A static technique for detecting input validation vulnerabilities in Android apps显示文摘Input validation vulnerabilities are common in Android apps, especially in inter-component communications. Malicious attacks can exploit this kind of vulnerability to bypass Android security mechanism and compromise the integrity, confidentiality and availability of Android devices. However, so far there is not a sound approach at the source code level for app developers aiming to detect input validation vulnerabilities in Android apps. In this paper, we propose a novel approach for detecting input validation flaws in Android apps and we implement a prototype named Easy IVD, which provides practical static analysis of Java source code.Easy IVD leverages backward program slicing to extract transaction and constraint slices from Java source code.Then Easy IVD validates these slices with predefined security rules to detect vulnerabilities in a known pattern.To detect vulnerabilities in an unknown pattern, Easy IVD extracts implicit security specifications as frequent patterns from the duplicated slices and verifies them. Then Easy IVD semi-automatically confirms the suspicious rule violations and reports the confirmed ones as vulnerabilities. We evaluate Easy IVD on four versions of original Android apps spanning from version 2.2 to 5.0. It detects 58 vulnerabilities including confused deputy attacks and denial of service attacks. Our results prove that Easy IVD can provide a practical defensive solution for app developers. | Zhejun FANG Qixu LIU Yuqing ZHANG Kai WANG Zhiqiang WANG Qianru WU | 2017 | Science China(Information Sciences)2017,60,5: | 5 |
| 5 | Characteristic analysis of phospholipid fatty acids (PLFAs) in typical nutrient polluted lake sediment in Wuhan显示文摘The process of urbanization aggravates the endogenous pollution of urban lake sediment,and polluted sediment may seriously affect the quality of the water in lakes.At present,it is difficult to distinguish the difference between sediment that is heavily polluted by nitrogen(N)and phosphorus(P)when using an analysis based on a physicochemical index classification.The current study applied phospholipid fatty acid(PLFA)technology to further analyze the sediment characteristics from the perspective of microbiology.Surface sediment from five urban lakes that are heavily polluted with N and P in Wuhan were sampled.Statistical approaches were used to analyze the microbial community structure in the sampled sediment,and to determine the correlations between the microorganisms and physicochemical indices.The most severely polluted lake sediment had similar PLFA structures,the highest saturated fatty-acid content,and bacteria as the dominant microorganism.However,there were differences between the microbial biomass of the various sediment samples,which may have been related to the degree of N and P pollution.Analysis of the microbial diversity in the sediment samples indicated that the bacteria were experiencing starvation and nutrient pressure,which may have been due to the dissolved oxygen concentration of the heavily polluted lake sediment.A correlation analysis showed that the endogenous N and P had different effects on the microbes of the polluted sediment.A redundancy analysis(RDA)demonstrated that the N/P ratio had the greatest influence on the PLFA species,accounting for 83%of the cumulative interpretation.To effectively promote the role of sediment microorganisms on circulating elements,it is necessary to regulate the N/P ratio of the sediment to some extent.When the N/P ratio in sediment exceeds 6,N pollution should be prioritized. | Xia Zhang Qianru Chen Chuan Wang Hongpei Zhang Yuqing Zhao Liping Zhang Biyun Liu Zhenbin Wu Qiaohong Zhou | 2021 | International Journal of Sediment Research2021,36,2: | 5 |
| 6 | Bulk growth and separation of single-walled carbon nanotubes from rhenium catalyst显示文摘Bulk synthesis of single-walled carbon nanotubes(SWNTs)using solid catalyst has been challenging,despite of recent breakthrough in the chirality-specific growth on the flat substrate surface.In this work,we propose a porous magnesia support rhenium catalyst for bulk synthesis of SWNTs.It is found that the well-dispersed catalyst with a high melting point and the optimal chemical vapor deposition reaction conditions account for the growth of SWNTs.Detailed characterizations reveal the produced SWNTs are dominant in(n,n−1)and(n,n−2)species.Furthermore,by using a multicolumn chromatography post-growth separation method,SWNTs with three defined diameter ranges were obtained.This work guides the design of porous oxide supported catalyst for bulk synthesis and diameter-dependent sorting of SWNTs,which will ultimately help harness the extraordinary properties of SWNTs. | Chen Ma Yumin Liu Lili Zhang Liu Qian Yiming Zhao Ying Tian Qianru Wu Dong Li Nan Zhao Xueting Zhang Liantao Xin Huaping Liu Pengxiang Hou Chang Liu Maoshuai He Jin Zhang | 2022 | Nano Research2022,15,7: | 2 |
| 7 | Surface Dyakonov-Cherenkov radiation显示文摘Recent advances in engineered material technologies(e.g.,photonic crystals,metamaterials,plasmonics,etc.)provide valuable tools to control Cherenkov radiation.In all these approaches,however,the particle velocity is a key parameter to affect Cherenkov radiation in the designed material,while the influence of the particle trajectory is generally negligible.Here,we report on surface Dyakonov-Cherenkov radiation,i.e.the emission of directional Dyakonov surface waves from a swift charged particle moving atop a birefringent crystal.This new type of Cherenkov radiation is highly susceptible to both the particle velocity and trajectory,e.g.we observe a sharp radiation enhancement when the particle trajectory falls in the vicinity of a particular direction.Moreover,close to the Cherenkov threshold,such a radiation enhancement can be orders of magnitude higher than that obtained in traditional Cherenkov detectors.These distinct properties allow us to determine simultaneously the magnitude and direction of particle velocities on a compact platform.The surface Dyakonov-Cherenkov radiation studied in this work not only adds a new degree of freedom for particle identification,but also provides an all-dielectric route to construct compact Cherenkov detectors with enhanced sensitivity. | Hao Hu Xiao Lin Liang Jie Wong Qianru Yang Dongjue Liu Baile Zhang Yu Luo | 2022 | eLight2022,2,1: | 1 |
| 8 | Redox Mediator Chemistry Regulated Aqueous Batteries:Insights into Mechanisms and Prospects显示文摘Redox mediators(RMs),serving as intermediate electron carriers or reservoirs,play vital roles in developing new charge transfer energy storage systems with high voltage or capacity in aqueous batteries.However,the underlying mechanism and selection criteria of RMs remain unclear in aqueous batteries,which hinders the further exploitation of new RMs and aqueous battery chemistries. | Tengsheng Zhang Qianru Chen Xinran Li Jiahao Liu Wanhai Zhou Boya Wang Zaiwang Zhao Wei Li Dongliang Chao Dongyuan Zhao | 2022 | CCS Chemistry2022,4,9: | 1 |
| 9 | The Application of Electron-Beam Welding in Pellet Mold Preparation显示文摘This paper provides insight into the application of electron-beam welding in pellet mold preparation,highlighting the importance of the combination of electron-beam welding and pellet mold preparation in the fields of microstructure joining and micro-and nanostructure preparation.Precise material joining and microstructure fabrication can be achieved by the precise control of electron-beam welding and the shape adjustment of pellet molds.These applications hold significant potential in the modern industrial field,providing robust support for the development of new materials and the growth of the petrochemical industry.This paper asserts that in the future,the ongoing development of electron-beam welding and pelletizing template technology will unlock new possibilities in the field of petrochemicals,fostering progress in science and technology. | Zhanqi Liu Mingjiang Bian Kun Li Qianru Lin | 2023 | Journal of Electronic Research and Application2023,7,6: | 0 |
| 10 | Salient pairwise spatio-temporal interest points for real-time activity recognition显示文摘 | Mengyuan Liu Hong Liu Qianru Sun Tianwei Zhang Runwei Ding | 2016 | CAAI Transactions on Intelligence Technology2016,1,1: | 0 |
| 11 | Genetic Insights into Glycine’s Protective Role Against CAD—European and East Asia,2015 and 2020显示文摘Introduction:The purpose of this study is to examine the potential causal relationship between levels of circulating glycine and coronary artery disease(CAD)using a two-step Mendelian randomization(MR)analysis.Methods:We analyzed data from genome-wide association studies(GWAS)conducted on European and East Asian populations.To assess the causal effects of circulating glycine levels on the risk of CAD.We used the inverse-variance weighting(IVW),weighted median(WM),MR-Egger,and Mendelian Randomization Pleiotropy RESidual Sum and Outlier(MR-PRESSO)methods.Furthermore,we conducted mediation analysis to investigate the contribution of blood pressure and other cardiovascular disease-related traits.Results:The two-step Mendelian randomization analysis revealed that higher levels of glycine in the blood were associated with a reduced risk of CAD in Europeans[odds ratio(OR)=0.84,95%confidence interval(CI):0.72,−0.98;P=0.029]and East Asians:(OR=0.76,95%CI:0.66,−0.89;P=3.57×10−4).Sensitivity analysis confirmed the robustness of these findings.Additionally,our results suggest that about 6.06%of the observed causal effect is mediated through genetically predicted systolic blood pressure(SBP)in the European population.Discussion:Our results contribute to the current knowledge regarding the involvement of glycine in the progression of CAD,and provide valuable methodological insights for the prevention and treatment of this condition. | Jiaying Yu Zhuolin Zhu Ting Wang Yuanhao Wei Lianjie Huang Qianru Zhang Yuting Zhang Yiran Wang Guiyou Liu Xiang Shu Rennan Feng | 2024 | China CDC weekly2024,6,9: | 0 |
| 12 | The Turbulent Schmidt Number for Transient Contaminant Dispersion in a Large Ventilated Room Using a Realizable k-εModel显示文摘Buildings with large open spaces in which chemicals are handled are often exposed to the risk of explosions.Computational fluid dynamics is a useful and convenient way to investigate contaminant dispersion in such large spaces.The turbulent Schmidt number(Sct)concept has typically been used in this regard,and most studies have adopted a default value.We studied the concentration distribution for sulfur hexafluoride(SF6)assuming different emission rates and considering the effect of Sct.Then we examined the same problem for a light gas by assuming hydrogen gas(H2)as the contaminant.When SF6 was considered as the contaminant gas,a variation in the emission rate completely changed the concentration distribution.When the emission rate was low,the gravitational effect did not take place.For both low and high emission rates,an increase in Sct accelerated the transport rate of SF6.In contrast,for H2 as the contaminant gas,a larger Sct could induce a decrease in the H2 transport rate. | Fei Wang Qinpeng Meng Jinchi Zhao Xin Wang Yuhong Liu Qianru Zhang | 2024 | Fluid Dynamics & Materials Processing2024,20,4: | 0 |
| 13 | Highly selective growth of(6,5)single-walled carbon nanotubes from sigma phase alloy catalyst显示文摘The chirality structure of a single-walled carbon nanotube(SWNT)strongly depends on the composition of catalyst used in the chemical vapor deposition process.In this study,we develop a porous magnesia supported manganese-rhenium(MnRe/MgO)catalyst for chirality-selective synthesis of SWNTs.Detailed characterizations reveal that(6,5)tubes with a selectivity higher than 70%are grown from the Re-rich MnRe/MgO catalyst.By comparing the SWNT growth results with those of monometallic Mn or Re,the formation of sigma phase,an intermetallic compound occurring in transition-metal alloy systems,is revealed to be crucial for the dominant synthesis of(6,5)SWNTs.This work not only extends the application of sigma phase alloy for catalytic synthesis of SWNTs,but also sheds lights on the growth of SWNTs with a high chirality selectivity. | Liantao Xin Chen Ma Qianru Wu Shaokang Liu Linhai Li Xiuyun Zhang Liu Qian Maoshuai He Dong Li Fangqian Han Shulan Hao Lihu Feng Yahan Li Huaping Liu Lili Zhang Chang Liu Jin Zhang | 2024 | Nano Research2024,17,3: | 0 |
| 14 | A nomogram-based immune-serum scoring system predicts overall survival in patients with lung adenocarcinoma显示文摘Objective:The immunoscore,which is used to quantify immune infiltrates,has greater relative prognostic value than tumor,node,and metastasis(TNM)stage and might serve as a new system for classification of colorectal cancer.However,a comparable immunoscore for predicting lung adenocarcinoma(LUAD)prognosis is currently lacking.Methods:We analyzed the expression of 18 immune features by immunohistochemistry in 171 specimens.The relationship of immune marker expression and clinicopathologic factors to the overall survival(OS)was analyzed with the Kaplan-Meier method.A nomogram was developed by using the optimal features selected by least absolute shrinkage and selection operator(LASSO)regression in the training cohort(n=111)and evaluated in the validation cohort(n=60).Results:The indicators integrated in the nomogram were TNM stage,neuron-specific enolase,carcino-embryonic antigen,CD8 center of tumor(CT),CD8 invasive margin(IM),Fox P3 CT,and CD45 ROCT.The calibration curve showed prominent agreement between the observed 2-and 5-year OS and that predicted by the nomogram.To simplify the nomogram,we developed a new immune-serum scoring system(I-SSS)based on the points awarded for each factor in the nomogram.Our I-SSS was able to stratify same-stage patients into different risk subgroups.The combination of I-SSS and TNM stage had better prognostic value than the TNM stage alone.Conclusions:Our new I-SSS can accurately and individually predict LUAD prognosis and may be used to supplement prognostication based on the TNM stage. | Qiujuan Huang Tongyuan Qu Lisha Qi Changxu Liu Yuhong Guo Qianru Guo Guangning Li Yalei Wang Wenshuai Zhang Wei Zhao Danyang Ren Leina Sun Shengguang Wang Bin Meng Baocun Sun Bin Zhang Wenjuan Ma Wenfeng Cao | 2021 | Cancer Biology & Medicine2021,18,2: | 0 |
| 15 | Eu-based anolytes for high-voltage and long-lifetime aqueous flow batteries显示文摘Aqueous flow batteries(AFBs) are among the most promising electrochemical energy storage solutions for the massive-scale adoption of renewable electricity because of decoupled energy and power, design flexibility, improved safety and low cost. The development of high-voltage AFB is, however, limited by the lack of stable anolytes that have low redox potential. Here we report Eu-based anolytes for high-voltage p H-neutral AFB applications. Eu^(3+) has a reduction potential of -0.39 V vs. SHE, which can be dramatically lowered when forming stable complex with inexpensive organic chelates. A typical complex, Eu DTPA,features a low redox potential of -1.09 V vs. SHE, fast redox kinetics, and a high water solubility of 1.5 M. When paired with ferrocyanide, the battery had an open-circuit voltage of 1.56 V and demonstrated stable cell cycling performance, including a capacity retention rate of 99.997% per cycle over500 cycles at 40 m A cm^(-2), a current efficiency of >99.9%, and an energy efficiency of >83.3%. A high concentration anolyte at 1.5 M exhibited a volumetric capacity of 40.2 Ah L^(-1), which is one of the highest known for p H-neutral AFBs, promising a potent solution for the grid-scale storage of renewable electricity. | Pan Sun Yahua Liu Peipei Zuo Yuanyuan Li Qianru Chen Zhengjin Yang Tongwen Xu | 2021 | Journal of Energy Chemistry2021,30,9: | 0 |
| 16 | Scientific and Technological Innovation Is an Important Approach to Ensuring China’s Oil Security显示文摘With the rapid and continual growth of national economy, the gap between oil demand and supply keeps widening in China, therefore China will increasingly depend on imported oil. However, the world’s oil and gas resources are unevenly distributed; global world’s oil prices remain high; and over 70 percent of China’s imported oil has to be shipped through the Malacca Strait. There are various ways to ensure China’s oil security today, and the practical and feasible strategic option is to increase the discovery and production of domestic oil, raise energy efficiency and develop petroleum substitutes. Scientific and technological innovation is crucial both in new oil reserves discovery and production, energy conservation, and in the development of petroleum substitutes, establishment of a strategic oil reserve system and for environment protection. This indicates that China should take effective measures in investment strategy, fiscal policies, financing instruments, intellectual property protection, fostering talents and professionals, so as to establish its own scientific and technological innovation system in the petroleum industry and be better able to ensure oil security. | Liu Qianru Wang Jianyong | 2006 | Petroleum Science2006,3,4: | 0 |
| 17 | Dysprosium regulated platinum particles as a bimetallic alloy catalyst for oxygen reduction reaction显示文摘Pt rare earth compounds have recently been investigated as potential substitutes.In this study,the hydrogen reduction method was used to prepare the Pt-Dy bimetallic catalyst,and a number of characterizations were conducted for structure and morphological research.The high resolutiontransmission electron microscopy(HR-TEM)and X-ray diffraction results show that Pt-Dy composite material exists in the form of various alloys and has a clear spherical shape.The majority of the metals in the composite catalyst appear in the zero valent state,and the binding energy of Pt shifts significantly,according to an X-ray photoelectron spectroscopy measurement.Impressively,Pt-Dy alloy produces excellent mass activity of 594 A/g compared to commercial Pt/C catalyst(162.8 A/g)for oxygen reduction process.Furthermore,after an accele rated durability test,the catalytic activity loss for Pt-Dy alloy catalyst reaches 20%while commercial Pt/C reduces 56%. | Qianru Liu Juan Qin Fengyun Huang Dawei Zhang Liheng Chen Feng Yin | 2023 | Journal of Rare Earths2023,41,8: | 0 |
| 18 | Fracture detecting based on Ant Colony Algorithm显示文摘Image processing plays an important role in engineering treatment. The authors mainly introduced the feature recognition of borehole image process based on Ant Colony Algorithm (ACA). The most important geological structure-fracture on the borehole image was identified, and quantitative parameters were obtained by HOUGH transform. Several case studies show that the method is feasible. | LIU Qianru XUE Linfu PAN Baozhi ZHANG Cheng'en MA Junming YU Henan QI Caisong | 2013 | Global Geology2013,16,2: | 0 |
| 19 | An adaptive system for detecting malicious queries in web attacks显示文摘Web request query strings(queries), which pass parameters to a referenced resource, are always manipulated by attackers to retrieve sensitive data and even take full control of victim web servers and web applications. However, existing malicious query detection approaches in the literature cannot cope with changing web attacks. In this paper, we introduce a novel adaptive system(AMOD) that can adaptively detect web-based code injection attacks, which are the majority of web attacks, by analyzing queries. We also present a new adaptive learning strategy, called SVM HYBRID, leveraged by our system to minimize manual work. In the evaluation, an up-to-date detection model is trained on a ten-day query dataset collected from an academic institute's web server logs. The evaluation shows our approach overwhelms existing approaches in two respects. Firstly, AMOD outperforms existing web attack detection methods with an F-value of 99.50%and FP rate of 0.001%. Secondly, the total number of malicious queries obtained by SVM HYBRID is3.07 times that by the popular support vector machine adaptive learning(SVM AL) method. The malicious queries obtained can be used to update the web application firewall(WAF) signature library. | Ying DONG Yuqing ZHANG Hua MA Qianru WU Qixu LIU Kai WANG Wenjie WANG | 2018 | Science China(Information Sciences)2018,61,3: | 0 |
| 20 | A cluster of mutagenesis revealed an osmotic regulatory role of the OsPIP1 genes in enhancing rice salt tolerance显示文摘Aquaporins play important regulatory roles in improving plant abiotic stress tolerance.To better understand whether the Os PIP1 genes collectively dominate the osmotic regulation in rice under salt stress,a cluster editing of the Os PIP1;1,Os PIP1;2 and Os PIP1;3 genes in rice was performed by CRISPR/Cas9 system.Sequencing showed that two mutants with Cas9-free,line 14 and line 18 were successfully edited.Briefly,line 14 deleted a single C base in both the Os PIP1;1 and Os PIP1;3 genes,and inserted a single T base in the Os PIP1;2 gene,respectively.While line 18 demonstrated an insertion of a single A base in the Os PIP1;1gene and a single T base in both the Os PIP1;2 and Os PIP1;3 genes,respectively.Multiplex editing of the Os PIP1 genes significantly inhibited photosynthetic rate and accumulation of compatible metabolites,but increased MDA contents and osmotic potentials in the mutants,thus delaying rice growth under salt stress.Functional loss of the Os PIP1 genes obviously suppressed the expressions of the Os PIP1,Os SOS1,Os CIPK24 and Os CBL4 genes,and increased the influxes of Na+and effluxes of K^(+)/H^(+)in the roots,thus accumulating more Na+in rice mutants under salt stress.This study suggests that the Os PIP1 genes are essential modulators collectively contributing to the enhancement of rice salt stress tolerance,and multiplex editing of the Os PIP1 genes provides insight into the osmotic regulation of the PIP genes. | Leyuan Tao Bing Wang Shichao Xin Wei Li Shengcai Huang Laihua Liu Jing Cui Qianru Zhang Xianguo Cheng | 2023 | The Crop Journal2023,11,4: | 0 |