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| 1 | Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future显示文摘Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide.Western medicine and therapies are the primary treatment strategies of hepatocellular carcinoma(HCC),but the general prognosis for HCC patients is still dismal.Under these circumstances,HCC prevention is particularly important.Traditional Chinese medicine(TCM)encompasses a wealth of documented therapeutic resources,and“preventative treatment”is the principle of TCM.In China,TCM has been used for HCC prevention for thousands of years,and has also been demonstrated to be effective for the treatment of HCC in modern China.However,the TCM theory for prevention and treatment of HCC is more widely accepted in China than abroad.In this review,we first summarize the herbs and ancient formulas with therapeutic effects on HCC.We also review the research status of TCM in modern medicine as well as the current obstacles in its development.Finally,we discuss the future of TCM in the context of precision and integrated medicine.After reviewing the literature,we believe that TCM,through ancient development,is an advanced method of cancer treatment with positive curative effects,despite its surrounding controversy.Furthermore,precise analyses and systematic research methods provides novel approaches to modernize TCM for the future. | Xia Liao Yang Bu Qingan Jia | 2020 | Genes & Diseases2020，7，3： | 11 |
| 2 | Primary structure of helix C to helix G of a new retinal protein in H.sp.xz515显示文摘The gene fragment encoding the retinal protein from helix C to helix G in a new strain of halobacteria, H.sp.xz515 has been amplified by PCR method. The nucleotide sequence of this fragment has been determined. The deduced amino acid sequence has been compared with halobium br and other two br-like proteins, ar-1 and ar-2. Results show that those amino acid residues in br, essential for proton pumping and binding to retinal, are conserved. The residue M145 in br may be important for isomerization reaction of retinal. | Hui Wang Shuxuan Zhan Qingan Sun Deqiang Xu Wei Zhao Weida Huang Qingguo Li | 2000 | Chinese Science Bulletin2000，45，12： | 5 |
| 3 | Staged angioplasty versus regular carotid artery stenting in patients with carotid artery stenosis at high risk of hyperperfusion:a randomised clinical trial显示文摘Background and purpose Hyperperfusion(HP)is a devastating complication associated with carotid artery stenting(CAS)or endarterectomy.The efficacy and safety of staged angioplasty(SAP)in patients with CAS at high risk of HP remains unclear.We sought to determine whether SAP is superior to regular CAS in patients with high risk of HP.Methods A randomised,multicentre open-label clinical trial with blinded outcome assessment(STEP)was conducted.Patients with severe carotid stenosis at high risk of HP were randomly assigned(1:1)to the SAP or regular CAS group.The primary endpoint was hyperperfusion syndrome(HPS)and intracerebral haemorrhage(ICH)within 30 days after the procedure.Results From November 2014 to January 2017,a total of 64 patients were enrolled in 11 centres.33 patients were allocated to the SAP group and 31 to the regular CAS group.At 30 days,the rate of primary endpoint was 0.0%(0/33)in the SAP group and 9.7%(3/31)in the regular CAS group(absolute risk reduction(ARR),9.7%;95%CI−20.1% to 0.7%;p=0.11).As one of the secondary endpoints,the incidence of HP phenomenon(HPP)was lower in the SAP group than the regular CAS group(0.0%vs 22.6%,ARR,−22.6%;95% CI−36.8%to−10.2%;p=0.04).Conclusion The rate of HPS and ICH was not significantly lower in SAP group;the extended secondary endpoint of HPP,however,significantly reduced,which suggested that SAP may be a safe and effective carotid revascularisation procedure to prevent HP. | Dapeng Mo Baixue Jia Huaizhang Shi Yaxuan Sun Qingan Liu Chengzhe Fan Jianping Deng Jinglin Yuan Wei Wu Changchun Jiang Guilian Zhang Hanjun Du Ning Ma Feng Gao Xuan Sun Ligang Song Lian Liu Guangge Peng Yongjun Wang Yilong Wang Zhongrong Miao the STEP Study Group | 2021 | Stroke & Vascular Neurology2021，6，1： | 3 |
| 4 | Study on pulsed laser ablation and deposition of ZnO thin films by L-MBE显示文摘ZnO,as a wide-band gap semiconductor,has recently become a new research fo-cus in the field of ultraviolet optoelectronic semiconductors. Laser molecular beam epitaxy(L-MBE) is quite useful for the unit cell layer-by-layer epitaxial growth of zinc oxide thin films from the sintered ceramic target. The ZnO ceramic target with high purity was ablated by KrF laser pulses in an ultra high vacuum to deposit ZnO thin film during the process of L-MBE. It is found that the deposition rate of ZnO thin film by L-MBE is much lower than that by conventional pulsed laser deposition(PLD) . Based on the experimental phenomena in the ZnO thin film growth process and the thermal-controlling mechanism of the nanosecond(ns) pulsed laser abla-tion of ZnO ceramic target,the suggested effective ablating time during the pulse duration can explain the very low deposition rate of the ZnO film by L-MBE. The unique dynamic mechanism for growing ZnO thin film is analyzed. Both the high energy of the deposition species and the low growth rate of the film are really beneficial for the L-MBE growth of the ZnO thin film with high crystallinity at low temperature. | HE YongNing ZHANG JingWen YANG XiaoDong XU QingAn ZHU ChangChun HOU Xun | 2007 | Science China(Technological Sciences)2007，50，3： | 3 |
| 5 | Pancreatic cancer serum biomarker PC-594:Diagnostic performance and comparison to CA19-9显示文摘AIM:To investigate serum PC-594 fatty acid levels as a potential biomarker in North American pancreatic cancer(PaC) patients,and to compare its performance to CA19-9.METHODS:Using tandem mass spectrometry,we evaluated serum PC-594 levels from 84 North American patients with confirmed PaC and 99 cancer-free control subjects.We determined CA19-9 levels by ELISA.Significance between Pa C patients and controls,and association with clinical variables was determined by analysis of variance and t-tests.Diagnostic performance was evaluated by receiver-operator characteristic(ROC)curve analysis,and PC-594 correlation with age and CA19-9 determined by regression analysis.RESULTS:Mean PC-594 levels were 3.7 times lower in Pa C patients compared to controls(P < 0.0001).The mean level in PaC patient serum was 0.76 ± 0.07 μmol/L,and the mean level in control subjects was 2.79 ± 0.15 μmol/L.There was no correlation between PC-594 and age,disease stage or gender(P > 0.05).Using 1.25 μmol/L as a PC-594 threshold produced a relative risk(RR) of 9.4(P < 0.0001,95%CI:5.0-17.7).The area under the receiver-operator characteristic curve(ROCAUC) was 0.93(95%CI:0.91-0.95) for PC-594 and 0.85(95%CI:0.82-0.88) for CA19-9.Sensitivity at 90% specificity was 87% for PC-594 and 71% for CA19-9.Six Pa C patients with CA19-9 above 35 U/m L showed normal PC-594 levels,while 24 Pa C patients with normal CA19-9 showed low PC-594 levels.Eighty-five of the 99 control subjects(86%) showed normal levels of both markers.CONCLUSION:PC-594 biomarker levels are significantly reduced in North American Pa C patients,and showed superior diagnostic performance compared to CA19-9. | Shawn A Ritchie Bassirou Chitou Qingan Zheng Dushmanthi Jayasinghe Wei Jin Asuka Mochizuki Dayan B Goodenowe | 2015 | World Journal of Gastroenterology2015，21，21： | 3 |
| 6 | Growth kinetics of MgH2 nanocrystallites prepared by ball milling显示文摘MgH2 is one of promising hydrogen storage materials due to its high hydrogen capacity of 7.6 wt%.However,MgH2 nanocrystallites easilygrow up during hydrogen absorption-desorption cycling,leading to deterioration of hydrogen storage properties.To clarify the growth kinetics of MgH2 crystallites,the growth characteristics of MgH2 nanocrystallites are investigated in this work.The growth exponents of MgH2 nanocrystallites in pure MgH2 and MgH2-10 wt% Pr3 Al11 samples are evaluated to be n=5 and n=6,respectively.Meanwhile,their activation energies for crystallite growth are also determined to be109.2 and 144.2 kJ/mol,respectively.The increase of growth exponent and rise of activation energy for crystallite growth in MgH2-10 wt% Pr3 Al11 composite are ascribed to the presence of nano-sized Pr3 Al11phase. | Caiqin Zhou Yayu Peng Qingan Zhang | 2020 | Journal of Materials Science & Technology2020，47，15： | 2 |
| 7 | Half-sandwich rhodium poly-chalcogenide complexes and a carbon insertion into Te-Te bond显示文摘Treatment of CptRh(PMe3)Cl2(1) (Cpt=5η-tBu2C5H3) with [Et4N]2Se6 in DMF solution leads to the for-mation of cyclo-tetraselenido half-sandwich rhodium com-plexes CptRh(PMe3)(Se4) (2). The elimination of 2 with ex-cess of nBu3P results in cyclo-diselenido rhodium complex CptRh(PMe3)(Se2) (3). 1 reacts with [nBu4N]2Te5 in DMF solution to yield cyclo-ditellurido rhodium complex CptRh (PMe3)(Te2) (4) in which carbon atom from CH2C12 can be inserted into Te-Te bond to form CptRh(PMe3)(TeCH2Te) (5). The new complexes 2-5 have been characterized by their IR, EI-MS, and 1H, 13C, 31P, 103Rh NMR spectra as well as ele-mental analysis. | Qingan Kong Guoxin Jin | 2002 | Chinese Science Bulletin2002，47，3： | 2 |
| 8 | Flip-chip packaging for a two-dimensional thermal flow sensor using a copper pillar bump technology 显示文摘 | SUN Jianbo QIN Ming HUANG Qingan | 2007 | IEEE Sensors Journal2007，，7： | 1 |
| 9 | Detonation Reactivity of Alkane and Alkene-air Mixtures显示文摘 | Wang Qingan Fan Weicheng | 2000 | Combustion and Flame2000，120，12： | 1 |
| 10 | Probing the catalytic activity of M-N_(4−x)O_(x) embedded graphene for the oxygen reduction reaction by density functional theory显示文摘In this work,the detailed oxygen reduction reaction(ORR)catalytic performance of M-N_(4−x)O_(x)(M=Fe,Co,and Ni;x=1−4)has been explored via the detailed density functional theory method.The results suggest that the formation energy of M-N_(4−x)O_(x)shows a good linear relationship with the number of doped O atoms.The adsorption manner of O_(2)on M-N_(4−x)O_(x)changed from end-on(x=1 and 2)to side-on(x=3 and 4),and the adsorption strength gradually increased.Based on the results for binding strength of ORR intermediates and the Gibbs free energy of ORR steps on the studied catalysts,we screened out two highly active ORR catalysts,namely Co-N_(3)O_(1)and Ni-N_(2)O_(2),which possess very small overpotentials of 0.27 and 0.32 V,respectively.Such activities are higher than the precious Pt catalyst.Electronic structure analysis reveals one of the reasons for the higher activity of Co-N_(3)O_(1)and Ni-N_(2)O_(2)is that they have small energy gaps and moderate highest occupied molecular orbital energy levels.Furthermore,the results of the density of states reveal that the O doping can improve the electronic structure of the original catalyst to tune the adsorption of the ORR intermediates. | Fan Ge Qingan Qiao Xin Chen You Wu | 2021 | Frontiers of Chemical Science and Engineering2021，15，5： | 1 |
| 11 | Response surface optimization of ultrasound-assisted oil ex- traction from autoclaved almond powder显示文摘 | Zhang Qingan Zhang Zhiqi Yue Xuanfeng | 2009 | Food Chem2009，116，2： | 1 |
| 12 | A novel capacitive-type humidity sensor using CMOS fabrication technology显示文摘 | Gu Lei Huang Qingan Qin Ming | 2004 | Sensors and Actuators B2004，99，2： | 1 |
| 13 | Kinematic evaluation of one-and two-level Maverick lumbar total disc replacement caudal to a long thoracolumabar spinal fusion显示文摘 | Qingan Z Timothy S Eyal I | | 0，，05： | 1 |
| 14 | Thread progress aware coherence adaption for hybrid cache coherence protocols 显示文摘 | Li Jianhua Shi Liang Li Qingan | 2013 | IEEE Trans on Parallel and Distributed Systems2013，25，10： | 1 |
| 15 | Low-energy volatile STT RAM cache design using cache coherence enabled adaptive refresh 显示文摘 | Li Jianhua Shi Liang Li Qingan | 2013 | ACM Trans on Design Automation of Electronic Systems (TODAES)2013，19，1： | 1 |
| 16 | Flip-Chip Packaging for a Two- Dimensional Thermal Flow Sensor Using a Copper Pillar Bump Technology显示文摘 | Jianbo Sun Ming Qin Qingan Hung | 2007 | IEEE sensors journal2007，7，7： | 1 |
| 17 | A mobile edge computing-based applications execution framework for Internet of Vehicles显示文摘Mobile edge computing(MEC)is a promising technology for the Internet of Vehicles,especially in terms of application offloading and resource allocation.Most existing offloading schemes are sub-optimal,since these offloading strategies consider an application as a whole.In comparison,in this paper we propose an application-centric framework and build a finer-grained offloading scheme based on application partitioning.In our framework,each application is modelled as a directed acyclic graph,where each node represents a subtask and each edge represents the data flow dependency between a pair of subtasks.Both vehicles and MEC server within the communication range can be used as candidate offloading nodes.Then,the offloading involves assigning these computing nodes to subtasks.In addition,the proposed offloading scheme deal with the delay constraint of each subtask.The experimental evaluation show that,compared to existing non-partitioning offloading schemes,this proposed one effectively improves the performance of the application in terms of execution time and throughput. | Libing WU Rui ZHANG Qingan LI Chao MA Xiaochuan SHI | 2022 | Frontiers of Computer Science2022，16，5： | 1 |
| 18 | Oxland translational constraint influences dynamic spinal canal occlusion of the thoracic spine: an in vitro experimental study 显示文摘 | Qingan Z Lane C Randal P | 2008 | J Biomech2008，41，1： | 1 |
| 19 | Preparation and characterization of polyacrylamide-intercalated graphite oxide显示文摘 | Jiayan Xu Yuan Hu Lei Song Qingan Wang Weicheng Fan | 2001 | Materials Research Bulletin2001，，10： | 1 |
| 20 | Mossbauer effect probe of field-induced magnetic phase transition in LaFe13-xSix intermetallic compounds 显示文摘 | Cheng Zhaohua Di Naili Li Qingan Kou Zhiqi Luo Zhi Ma Xiao Wang Guangjun Hu Fengxia Shen Baogen | 2004 | Applied Physics Letters2004，85，10： | 1 |
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