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| 1 | Arbuscular mycorrhizal fungi ameliorate the chemical properties and enzyme activities of rhizosphere soil in reclaimed mining subsidence in northwestern China显示文摘In semi-arid region of northwestern China, underground mining subsidence often results in decreased vegetation coverage, impoverishment of soil fertility and water stress. In addition, the physical-chemical and biological properties of soil also change, resulting in more susceptible to degradation. In particular, subsidence causes disturbance of the symbioses of plant and microbe that can play a beneficial role in the establishment of vegetation communities in degraded ecosystems. The objective of this study was to evaluate the effects of revegetation with exotic arbuscular mycorrhizal fungi(AMF) inoculum on the chemical and biological properties of soil over time in mining subsidence areas. Soils were sampled at a depth up to 30 cm in the adjacent rhizosphere of Amorpha fruticose Linn. from five reclaimed vegetation communities in northwestern China. In August 2015, a field trial was set up with five historical revegetation experiments established in 2008(7-year), 2011(4-year), 2012(3-year), 2013(2-year) and 2014(1-year), respectively. Each reclamation experiment included two treatments, i.e., revegetation with exotic AMF inoculum(AMF) and non-AMF inoculum(the control). Root mycorrhizal colonization, glomalin-related soil protein(GRSP), soil organic carbon(SOC), soil nutrients, and enzyme activities were also assessed. The results showed that mycorrhizal colonization of inoculated plants increased by 33.3%–163.0% compared to that of non-inoculated plants(P<0.05). Revegetation with exotic AMF inoculum also significantly improved total GRSR(T-GRSP) and easily extracted GRSP(EE-GRSP) concentrations compared to control, besides the T-GRSP in 1-year experiment and the EE-GRSP in 2-year experiment. A significant increase in SOC content was only observed in 7-year AMF reclaimed soils compared to non-AMF reclaimed soils. Soil total N(TN), Olsen phosphorus(P) and available potassium(K) were significantly higher in inoculated soil after 1–7 years of reclamation(except for individual cases), and increased with reclamation time(besides soil Olsen P). The exotic AMF inoculum markedly increased the average soil invertase, catalase, urease and alkaline phosphatase by 23.8%, 21.3%, 18.8% and 8.6%, respectively(P<0.01), compared with the control. Root mycorrhizal colonization was positively correlated with soil parameters(SOC, TN and soil available K) and soil enzyme activities(soil invertase, catalase, urease and alkaline phosphatase) in both AMF and non-AMF reclaimed soils(P<0.05), excluding availableK in non-AMF reclaimed soils. T-GRSP(P<0.01) and EE-GRSP(P<0.05) were significantly correlated with the majority of edaphic factors, except for soil Olsen P. The positive correlation between root mycorrhizal colonization and available K was observed in AMF reclaimed soils, indicating that the AMF reclaimed soil with a high root mycorrhizal colonization could potentially accumulate available K in soils. Our findings concluded that revegetation with exotic AMF inoculum influenced soil nutrient availability and enzyme activities in the semi-arid ecosystem, suggesting that inoculating AMF can be an effective method to improve soil fertility and support restoration of vegetation communities under poor conditions like soil nutrient deficiency and drought. | QIU Lang BI Yinli JIANG Bin WANG Zhigang ZHANG Yanxu Yryszhan ZHAKYPBEK | 2019 | Journal of Arid Land2019，11，1： | 11 |
| 2 | How does China’s stock market react to the announcement of the COVID-19 pandemic lockdown?显示文摘In this paper,we study how China’s stock market reacts to the sudden outbreak of COVID-19 in 2020,particularly to the announcement of the pandemic lockdown.In general,we observe reversals both at the industry level and at the firm level due to investors’overreactions to the pandemic lockdown.For industryand firm-level stocks with positive cumulative abnormal returns(CARs)in the event window when Wuhan was locked down,the reversals are stronger.Thus,the reversal effects are mostly driven by industries and stocks that positively overreact to COVID-19 than do others.Further investigation shows that overreactions are stronger for stocks with lower institutional ownership,which means that retail investors react more strongly to COVID-19.Among stocks with positive CARs in the event window,those with higher idiosyncratic volatilities and lower book-to-market ratios tend to have worse performance after one month. | Xiaolin Huo Zhigang Qiu | 2020 | Economic and Political Studies2020，8，4： | 4 |
| 3 | Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study显示文摘 | Qiujin Shen Jia Fan Xin-Rong Yang Yexiong Tan Weifeng Zhao Yang Xu Ning Wang Yongdong Niu Zheng Wu Jian Zhou Shuang-Jian Qiu Ying-Hong Shi Bin Yu Ning Tang Wei Chu Min Wang Jinhua Wu Zhigang Zhang Shengli Yang Jianren Gu Hongyang Wang Wenxin Qin | 2012 | Lancet Oncology2012，，8： | 4 |
| 4 | Involvement of Ghrelin-Growth Hormone Secretagogue Receptor System in Pathoclinical Profiles of Digestive System Cancer显示文摘Ghrelin 受体被显示了沿着人的胃肠的道被表示。最近的研究证明 ghrelin 和合成 ghrelin 受体收缩筋改进了重量获得和瘦身体质量在由对 ghrelin 受体起作用的癌症极度瘦弱的一个老鼠模型的保留,也就是说生长荷尔蒙促泌素受体(GHS-R ) 。这研究试图在人的胃肠的道癌症探索表示和 ghrelin 受体的分发并且在人的消化癌症调查 ghrelin-GHS-R 系统的可能的参与。外科的人的消化癌症标本从不同病人从胃肠的道的各种各样的部分被获得。在这些纸巾的 ghrelin 受体的表达式被织物检测微数组技术。我们的结果证明那 ghrelin 受体在整个胃肠的道在癌症被表示,主要在 mucosal 层房间的细胞质。它的表示水平可能与病人的机关类型,组织学的等级, tumor-nodes-metastases 阶段,和营养地位(重量损失) 相关。第一次,我们在消化系统癌症识别了 ghrelin 受体的分发。我们的结果暗示 ghrelin-GHS-R 系统可能涉及消化癌症的 pathoclinical 侧面。 | Zhigang WANG Weigang WANG Wencai QIU Youben FAN Jun ZHAO Yu WANG Qi ZHENG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，12： | 3 |
| 5 | Multi-Gradient Routing Protocol for Wireless Sensor Networks显示文摘Sensor networks tend to support different traffic patterns since more and more emerging applications have diverse needs. We present MGRP, a Multi-Gradient Routing Protocol for wireless sensor networks, which is fully distributed and efficiently supports endto-end, one-to-many and many-to-one traffic patterns by effectively construct and maintain a gradient vector for each node. We further combine neighbor link estimation with routing information to reduce packet exchange on network dynamics and node failures. We have implemented MGRP on Tiny OS and evaluated its performance on real-world testbeds. The result shows MGRP achieves lower end-to-end packet delay in different traffic patterns compared to the state of the art routing protocols while still remains high packet delivery ratio. | Ying Qiu Shining Li Zhigang Li Yu Zhang Zhe Yang | 2017 | China Communications2017，14，3： | 3 |
| 6 | Magnetic properties and magnetocaloric effects in amorphous and crystalline Gd_(55)Co_(35)Ni_(10) ribbons显示文摘The magnetic properties and magnetocaloric effects of amorphous and crystalline Gd55Co35Ni10 ribbons are investigated.A main phase with a Ho 12 Co 7-type monoclinic structure(space group P21/c) and a minor phase with a Ho4Co3-type hexagonal structure(space group P63/m) are obtained for crystalline ribbon after annealing.The amorphous ribbons order ferromagnetically and undergo a second-order transition at 192 K.For crystalline Gd55Co35Ni10 ribbons,two magnetic phase transitions occur at 158 and 214 K,respectively.The peak value of-△SM under a field change of 0-5 T is 6.5 J/kg K at 192 K for amorphous Gd55Co35Ni10 ribbons.A relatively large magnetic entropy change(~5.0 J/kg K) under a field change of 0-5 T for the crystalline Gd55Co35Ni10 ribbons is obtained in the temperature interval range of 154-214 K.The large platform of magnetic entropy change and the negligible thermal/magnetic hysteresis loss mean the crystalline Gd55Co35Ni10 compound can satisfy the requirement of the Ericsson-type refrigerator working in the temperature range from 154K to 214K. | ZHONG XiChun TANG PengFei GAO BeiBei MIN JiXiong LIU ZhongWu ZHENG ZhiGang ZENG DeChang YU HongYa QIU WanQi | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，6： | 3 |
| 7 | Nontoxic virus nanofibers improve the detection sensitivity for the anti-p53 antibody, a biomarker in cancer patients显示文摘在浆液的 anti-p53 抗体的存在是为癌症的 biomarker。然而,它的高敏感察觉仍然是在癌症诊断的一个问题。处理这挑战,我们使用了 fd 噬菌体,对人安全的细菌特定的病毒 nanofiber 那能被以一种无差错的方式感染主人细菌大量生产,并且遗传上设计了它显示能够在它的方面墙上认出并且捕获 anti-p53 抗体的肽。我们作为一根俘获探针采用了结果的噬菌体 nanofibers 开发连接酶的 immunosorbent 试金(ELISA ) 的一个修改版本方法,称为的 phage-ELISA。我们为 anti-p53 抗体的察觉把它比作传统的 ELISA 方法, p53-ELISA,哪个使用 recombinant 捕获 anti-p53 的野类型的 p53 蛋白质抗体。我们使用了 phage-ELISA 与恶意的肿瘤的各种各样的类型在 316 个病人的一个试验性的组检测 anti-p53 抗体。我们发现 17.7% 的察觉率(56 个积极盒子) 被 phage-ELISA 完成,它为 p53-ELISA (65 个积极盒子) 比得上 20.6% 的察觉率。然而,当噬菌体和 p53 被联合为 phage/p53-ELISA 形成捕获抗体的探针时, 30.4% 的察觉率(96 个积极盒子) 被完成。我们的工作证明由于由噬菌体 nanofibers 和 p53 的 anti-p53 抗体的联合俘获, phage/p53-ELISA 与癌症的各种各样的类型在病人为 anti-p53 抗体完成了最高诊断的精确性和察觉效率。我们的工作建议那 nanofibers 和抗原的联合,哪个俘获抗体,能导致增加的察觉敏感,它为在生命科学,临床的药,和环境科学的应用是有用的。 | Pengtao Pan Yicun Wang Ye Zhu Xiang Gao Zhigang Ju Penghe Qiu Li Wang Chuanbin Mao | 2015 | Nano Research2015，8，11： | 3 |
| 8 | Chest radiographic characteristics of community-acquired Legionella pneumonia in the elderly显示文摘 | Zhang Zhigang Liu Xinmin Chen Luzeng Qiu Jianxing | 2014 | Chinese Medical Journal2014，，12： | 2 |
| 9 | 高原哺乳动物瘤胃微生物组的趋同进化显示文摘动物对极端环境的适应机制一直是物种适应性进化研究的热点。青藏高原土著动物牦牛为此提供了一个经典案例。通过解析牦牛基因组已阐明了其适应高原极端环境的遗传学机制。 | Zhigang Zhang Dongming Xu Li Wang Junjun Hao Jinfeng Wang Xin Zhou Weiwei Wang Qiang Qiu Xiaodan Huang Jianwei Zhou 龙瑞军 赵方庆 施鹏 | 2017 | 科学新闻2017，19，4： | 2 |
| 10 | On-demand assembly of polymeric nanoparticles for longer-blood-circulation and disassembly in tumor for boosting sonodynamic therapy显示文摘Sonodynamic therapy (SDT) is one of the promising strategies for tumor therapy, but its application is usually hindered by fast clearance in blood-circulation, abnormal tumor microenvironment, and inefficient generation of reactive oxygen species. To solve these problems, we proposed an on-demand assembly-disassembly strategy, where the assembly is favorable for longer-blood-circulation and then the disassembly in tumor is favorable for boosting SDT. Hematoporphyrin monomethyl ether (HMME) as the model of organic sonosensitizers were conjugated with hyaluronic acid (HA). Then HA-HMME was mixed with catalase (CAT) and assembled into polymeric nanoparticles (CAT@HA-HMME NPs) with size of ~80 nm. CAT@HA-HMME NPs exhibit good biocompatibility and a longer blood half-time (t1/2 = 4.17 h) which is obviously longer than that (~0.82 h) of HMME molecules. After HA receptor-mediated endocytosis of cancer cells, CAT@HA-HMME NPs can be cleaved by endogenous hyaluronidase, resulting in the on-demand disassembly in tumor to release HA-HMME molecules and CAT. The CAT catalyzes the endogenous H_(2)O_(2) into O_(2) to relieve the hypoxic microenvironment, and the released HA-HMME exhibits a higher ROS generation ability, greatly boosting SDT for the inhibition of tumor growth. Therefore, the on-demand assembly-disassembly strategy may provide some insight in the design and development of nanoagents for tumor therapy. | Mei Wen Nuo Yu Shiwen Wu Mengmeng Huang Pu Qiu Qian Ren Meifang Zhu Zhigang Chen | 2022 | Bioactive Materials2022，7，12： | 2 |
| 11 | γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer显示文摘 | Pin Wu Dang Wu Chao Ni Jun Ye Wuzhen Chen Guoming Hu Zhen Wang Changrong Wang Zhigang Zhang Wenjie Xia Zhigang Chen Ke Wang Tao Zhang Jinghong Xu Yuehua Han Ting Zhang Xianguo Wu Jianwei Wang Weihua Gong Shu Zheng Fuming Qiu Jun Yan Jian Huang | 2014 | Immunity2014，，5： | 2 |
| 12 | Noninvasive Ultrasound Stimulation of Ventral Tegmental Area Induces Reanimation from General Anaesthesia in Mice显示文摘Evidence in animals suggests that deep brain stimulation or optogenetics can be used for recovery from disorders of consciousness(DOC).However,these treatments require invasive procedures.This report presents a noninvasive strategy to stimulate central nervous system neurons selectively for recovery from DOC in mice.Through the delivery of ultrasound energy to the ventral tegmental area,mice were aroused from an unconscious,anaesthetized state in this study,and this process was controlled by adjusting the ultrasound parameters.The mice in the sham group under isoflurane-induced,continuous,steady-state general anaesthesia did not regain their righting reflex.On insonation,the emergence time from inhaled isoflurane anaesthesia decreased(sham.13.63±0.53 min,ultrasound.1.5±0.19 min,p<0.001).Further,the induction time(sham.12.0±0.6 min,ultrasound.17.88±0.64 min,p<0.001)and the concentration for 50%of the maximal effect(EC50)of isoflurane(sham.0.6%,ultrasound.0.7%)increased.In addition,ultrasound stimulation reduced the recovery time in mice with traumatic brain injury(sham.30.38±1.9 min,ultrasound.7.38±1.02 min,p<0.01).This noninvasive strategy could be used on demand to promote emergence from DOC and may be a potential treatment for such disorders. | Tianyuan Bian Wen Meng Meihong Qiu Zhigang Zhong Zhengrong Lin Junjie Zou Yibo Wang Xiaowei Huang Lisheng Xu Tifei Yuan Zhili Huang Lili Niu Long Meng Hairong Zheng | 2021 | Research2021，，1： | 2 |
| 13 | Full-length sequence analysis of hepatitis E virus isolates: showing potential determinants of virus genotype and identity显示文摘 | Dong Yang Mei Jiang Min Jin Zhigang Qiu Weihong Cui Zhiqiang Shen Bo Li Lianfeng Gong Zhaoli Chen Xinwei Wang Jun-Wen Li | 2013 | Virus Genes2013，，3： | 1 |
| 14 | Reduction Behavior of Panzhihua Titanomagnetite Concentrates with Coal显示文摘 | Tu Hu Xuewei Lv Chenguang Bai Zhigang Lun Guibao Qiu | 2013 | Metallurgical and Materials Transactions B2013，，2： | 1 |
| 15 | Insulin-like growth factor-2 enhances regulatory T cell functions and suppresses food allergy in an experimental model显示文摘 | Gui Yang Xiao-Rui Geng Jiang-Ping Song Yingying Wu Hao Yan Zhengke Zhan Litao Yang Weiyi He Zhi-Qiang Liu Shuqi Qiu Zhigang Liu Ping-Chang Yang | 2014 | The Journal of Allergy and Clinical Immunology2014，，： | 1 |
| 16 | Policy on international R&D cooperation: Subsidy or tax? 显示文摘 | Larry D Qiu Zhigang Tao | 1998 | European Economic Review1998，42，： | 1 |
| 17 | Generation and control of dynamically tunable circular Pearcey beams with annular spiral-zone phase显示文摘Light-field shaping technology plays an important role in optics and nanophotonics. For instance, the spatially structured light field, which exhibits characteristic features in complex phases, light intensity, and polarization, is crucial to understanding new physical phenomena and exploring practical applications. Herein, we propose and demonstrate a new class of tunable circular Pearcey beams(TCPBs) by imposing the annular spiral-zone phase(ASZP). Through experiments, we used a spatial light modulator to generate TCPBs based on their spiral phase distribution, and numerically analyzed the generation and control of the beams with unusual autofocusing and self-rotating dynamics. ASZP is a general term for complex phases composed of the spiral phase,equiphase, and radial phase. TCPB typically exhibits dynamical properties, including abrupt autofocusing, automatic generation of optical bottles, and self-rotation of the beam pattern, during propagation. Besides, the number of generated optical bottles can be modulated by the superposition mode of ASZP and the number of subphases. We found that an inappropriate superposition mode leads to distortion, and we analyzed the underlying mechanism. Potential applications of TCPBs in optical manipulation are also discussed, presenting an exemplary role desired for light-field manipulation. | KaiHui Chen HuiXin Qiu You Wu ZeJia Lin HaiQi Huang LingLing Shui DongMei Deng HongZhan Liu ZhiGang Chen | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，10： | 1 |
| 18 | Policy on International R&D Coopera- tion:Subsidy or Tax? 显示文摘 | Qiu Larry D Tao Zhigang | 1998 | European Economic Review1998，，42： | 1 |
| 19 | QCM immunosensor detection of Escherichia coli O157∶H7 based on beacon immunomagnetic nanoparticles and catalytic growth of colloidal gold显示文摘 | Shen Zhiqiang Wang Jingfeng Qiu Zhigang | 2011 | Biosensors and Bioelectronics2011，26，： | 1 |
| 20 | Dynamic and distribution of ammonia-oxidizing bacteria communities during sludge granulation in an aerobic sequencing batch reactor显示文摘 | ZHANG Bin CHEN Zhe QIU Zhigang | 2011 | Water Research2011，45，6： | 1 |
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