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| 1 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015,25,8: | 8 |
| 2 | Bio-inspired polygonal skeleton structure for vibration isolation:Design,modelling,and experiment显示文摘Inspired by the safe landing of a cat falling from a high altitude,a bio-inspired polygonal skeleton(BIPS) structure is proposed,and its nonlinear characteristics are systematically studied to explore its potential application in the suppression of vibration. The polygon is formed by the skeleton structure of the cat’s entire body and the ground. The BIPS system consists of two symmetrical bionic legs with three robs(as skeleton) and four horizontal springs(as muscle). Two bionic legs are connected through the bearing platform(as spine),which could adjust the distance between the two bionic legs. A theoretical model is developed to characterize its stiffness nonlinearity through geometrical and mechanical analysis. Parameter analysis reveals that the BIPS structure has diverse stiffness,including nonlinear positive stiffness and negative stiffness. By imitating adjustment of leg posture and telescopic function of the spine(control the distance between legs),these flexible stiffness properties can be adjusted by structure parameters. In addition,the load capacity and working range can also be designed by the length of the bars,the initial angle,the mounting position,and the spring stiffness. The experimental setup is established,and the vibration isolation performance under various excitation is tested. The experimental results verify the accuracy of the dynamic model and also show that the proposed BIPS structure can suppress the vibration effectively under a variety of excitations. These peculiarities may provide potential possibility of an innovative approach to passive vibration control and isolation. | YAN Ge WANG Sen ZOU HongXiang ZHAO LinChuan GAO QiuHua ZHANG WenMing | 2020 | Science China(Technological Sciences)2020,63,12: | 5 |
| 3 | Design,modeling and experimental investigation of a magnetically modulated rotational energy harvester for low frequency and irregular vibration显示文摘Vibration energy harvesting is a promising approach for sustainable energy generation from ambience to meet the development of self-powered systems.Here,we propose a novel compact non-resonant magnetically modulated rotational energy harvester(MMR-EH)for low frequency and irregular vibration.Through the rational arrangement of multiple magnetic fields in space,a ring route with low potential energy is established.A movable magnet can be non-contact modulated by the magnetic force to move along the ring route under irregular vibration,which is instrumental in electromechanical energy conversion.A dynamic model of the MMR-EH is developed based on the energy method and verified experimentally.The effects of key parameters on the magnetically modulated route are analysed.The simulation and experimental results demonstrate that the MMR-EH can effectively harvest the energy from ultra-low frequency(3 Hz)and irregular vibration.At a reciprocating vibration frequency of 10 Hz and an amplitude of 20 mm,the harvester can produce an average power of 0.29 mW. | ZHAO LinChuan ZOU HongXiang GAO QiuHua YAN Ge WU ZhiYuan LIU FengRui WEI KeXiang YANG Bin ZHANG WenMing | 2020 | Science China(Technological Sciences)2020,63,10: | 5 |
| 4 | Magnetic levitation using diamagnetism:Mechanism,applications and prospects显示文摘As a typical contact-free manipulation technique that removes friction and contamination risk,levitation has gradually become a preferred candidate for various applications.Magnetic levitation using diamagnetism,beyond Earnshaw’s theorem,is a kind of passive stable levitation that can be achieved at normal temperatures with no energy input.Appealingly,most seemingly nonmagnetic materials can be levitated in a magnetic field and can stabilize free levitation of magnetic materials.This review focuses on the fundamental principles of magnetic levitation using diamagnetism,with emphasis on its burgeoning applications.The theoretical basis associated with the magnetic levitation using diamagnetism is discussed by elucidating the characteristics of diamagnetic materials,and the key levitation mechanisms are clarified.Afterwards,state-of-the-art applications in various aspects,including sensing and measurement,actuating and micromanipulation,energy harvesting and magnetic gravity compensation,are summarized and compared.Finally,the review concludes with a brief outlook on future perspectives. | GAO QiuHua YAN Han ZOU HongXiang LI WenBo PENG ZhiKe MENG Guang ZHANG WenMing | 2021 | Science China(Technological Sciences)2021,64,1: | 3 |
| 5 | Crystallization Behavior of High Purity Fused Magnesia显示文摘The chemical composition and microstructure of Tibetan microcrystalline magnesite were studied by means of XRF,XRD and FESEM. It is found that the microcrystalline magnesite has uniformly distributed grains,mostly in the range of 2-4 μm,and the MgO content is47. 80%. In fused magnesia,the druses are colorless transparent periclase megacrysts without impurity,while the crust sand is white,with a high MgO content up to97%-99%. The periclase crystals are big,appearing as faced and step-growth morphology. Massive secondary long columnar periclase is crystallized. | LI Xuejun GAO Zhenxin YAN Guanghui ZHANG Wei FU Qiuhua | 2017 | China's Refractories2017,26,2: | 2 |
| 6 | Study of luminescence properties of novel Er^3+ single-doped and Er^3+/Yb^3+ co-doped tellurite glasses显示文摘 | Gao Yuan Nie Qiuhua Xu Tiefeng | 2005 | Spectrochimica Acta:Part A2005,61,: | 1 |
| 7 | Local regularity for solutions of anisotropic obstacle problems显示文摘 | Hongya Gao Qiuhua Huang | 2012 | Nonlinear Analysis2012,,13: | 1 |
| 8 | Smart palm-size optofluidic hematology analyzer for automated imaging-based leukocyte concentration detection显示文摘A critical function of flow cytometry is to count the concentration of blood cells,which helps in the diagnosis of certain diseases.However,the bulky nature of commercial flow cytometers makes such tests only available in hospitals or laboratories,hindering the spread of point-of-care testing(POCT),especially in underdeveloped areas.Here,we propose a smart Palm-size Optofluidic Hematology Analyzer based on a miniature fluorescence microscope and a microfluidic platform to lighten the device to improve its portability.This gadget has a dimension of 35×30×80 mm and a mass of 39 g,less than 5%of the weight of commercially available flow cytometers.Additionally,automatic leukocyte concentration detection has been realized through the integration of image processing and leukocyte counting algorithms.We compared the leukocyte concentration measurement between our approach and a hemocytometer using the Passing-Bablok analysis and achieved a correlation coefficient of 0.979.Through Bland-Altman analysis,we obtained the relationship between their differences and mean measurement values and established 95%limits of agreement,ranging from−0.93×10^(3)to 0.94×10^(3)cells/μL.We anticipate that this device can be used widely for monitoring and treating diseases such as HIV and tumors beyond hospitals. | Deer Su Xiangyu Li Weida Gao Qiuhua Wei Haoyu Li Changliang Guo Weisong Zhao | 2023 | Opto-Electronic Science2023,2,12: | 1 |
| 9 | Effect of mela tonin on the generation of nitric oxide in murine macrophages 显示文摘 | Shen Zhang Wei Li Qiuhua Gao | 2004 | European Journal of Pharmacology2004,501,: | 1 |
| 10 | Detailed seafloor geomorphology of the western region of the North Yellow Sea,China:The result of Holocene erosional and depositional processes sculpting the offshore continental shelf显示文摘High-resolution multi-beam/single-beam bathymetric data and seismic profiling data from the latest surveys are used to map and interpret the detailed seafloor geomorphology of the western region of the North Yellow Sea(NYS),China.The mapping area covers 156410 km^(2),and incorporates a flat shelf plain,subaqueous accumulation shoals,tidal scouring troughs,and tidal sand ridge groups.Offshore areas with water depths less than 50 m in the western region of the NYS are mainly covered by thick,loose sediments,forming wide spread accumulation geomorphological features;these include the Liaodong Peninsula subaqueous accumulation system containing shoals and rugged scouring troughs,and the large mud wedge of the Shandong Peninsula.In the central part of the NYS,there is a relatively flat residual shelf plain with coarser sediment deposits.This flat shelf plain has a water depth larger than 50 m and a thin layer of sediment,on which there is a large pockmark field caused by seafloor seepage.These geomorphological structures indicate that modern sedimentary processes are the main driving force controlling the sculpture of the current seafloor surface landform.Extensive strong tidal current systems and abundant sediment sources provide the critical external forces and essential conditions for the formation of seafloor geomorphology.The tectonic basement controls the macroscopic morphological shape of the NYS,but is reflected very little in the seafloor geomorphic elements.Our results provide a detailed seafloor geomorphological map of the western region of the NYS,an area that has not previously mapped and also provide a scientific framework for further research into offshore seafloor geomorphology,shelf sedimentary processes,and submarine engineering construction in this region. | Xiaoyu Liu Yilan Chen Chenguang Liu Qiuhua Tang Yanhong Wang Shan Gao | 2022 | Acta Oceanologica Sinica2022,41,12: | 0 |
| 11 | An ISGW Filtering Antenna with Spurious Modes and Surface Wave Suppression for Millimeter Wave Communications显示文摘In this paper,an integrated substrate gap waveguide(ISGW)filtering antenna is proposed at millimeter wave band,whose surface wave and spurious modes are simultaneously suppressed.A secondorder filtering response is obtained through a coupling feeding scheme using one uniform impedance resonator(UIR)and two stepped-impedance resonators(SIRs).To increase the stopband width of the antenna,the spurious modes are suppressed by selecting the appropriate sizes of the ISGW unit cell.Furthermore,the ISGW is implemented to improve the radiation performance of the antenna by alleviating the propagation of surface wave.And an equivalent circuit is investigated to reveal the working principle of ISGW.To demonstrate this methodology,an ISGW filtering antenna operating at a center frequency of 25 GHz is designed,fabricated,and measured.The results show that the antenna achieves a stopband width of 1.6f0(center frequency),an out-of-band suppression level of 21 dB,and a peak realized gain of 8.5 dBi. | Lihui Wang Dongya Shen Qiuhua Lin Zhiyong Luo Wenjian Wang Jianpei Chen Zhao Gao Wei Zhang | 2023 | China Communications2023,20,11: | 0 |
| 12 | Evaluation and Selection of Introduced Tree Species in the Beijing-Tianjin Corridor显示文摘Based on the extensive analysis of natural and social conditions,regional development,and characteristics of tree species in the Beijing-Tianjin corridor,a comprehensive evaluation index system that consists of A,B,C,D layers was established for introduced tree species.Nine local representative introduced tree species were evaluated using the analytic hierarchy process(AHP).The results showed that Platanus orientalis,Quercus mongolicus,and Zizyphusjujube performed better comprehensively and were recommended as the dominant introduced tree species in the Beijing-Tianjin corridor.Other representative introduced tree species should be appropriately developed in the region.Main factors that should be taken into account for introduced tree species including drought tolerance,wintering habit,growth rate,leanness tolerance,pollution tolerance,saline tolerance,and disease resistance. | YUAN Wenge ZHENG Jianwei GU Jiancai LU Guiqiao GAO Qiuhua | 2018 | Journal of Landscape Research2018,10,5: | 0 |
| 13 | A trans-ortho asymmetrically di-strapped metalloporphyrin integrating three key structural features of ligand in heme显示文摘Heme responsible for the dioxygen fixation,transport and conversion is a metalloporphyrin complex highly dependent on its diverse geometry of ligand.In this work,a trans-ortho-di-strapped zinc porphyrin with dome-like deformation was synthesized by thermodynamically controlling the formation of transprecursor of porphyrinogen.Its single-crystal structure demonstrated that the asymmetric treatment of porphyrin achieves three goals of creating two secondary coordination sphere(SCS)bulks,maintaining a unique dome deformation,and making atomic out-of-plane deviation.In this way,this metallic complex integrates at least three key features of the pocket structure,the differentiated axial ligations,and the ring distortion,making it an ideal heme analog. | Qiuhua Liu Junhao Gao Yusheng Zhang Xin Liu Xi Zhang Qin Lin Wennan Zeng Zaichun Zhou | 2023 | Chinese Chemical Letters2023,34,10: | 0 |