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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation显示文摘PTEN 肿瘤 suppressor 是在调整 phosphatidylinositol-3-kinase (PI3K ) 有一个中央角色的类脂化合物磷酸酶信号 transduction 串联。不过, PTEN 活动被在房间调整的机制需要进一步的说明。尽管以前的研究证明了 PTEN 的 ubiquitination 能调制它的稳定性和 subcellular 本地化,在 PTEN 功能的最批评的方面的 ubiquitination 的角色,它的磷酸酶活动,充分没被探讨。这里,我们识别 PTEN 的新奇 E3 ubiquitin ligase,沤手指蛋白质(RFP ) ,那能支持 PTEN 的不正常的 polyubiquitinations。这些 ubiquitinations 不导致 PTEN 不稳定性或本地化,但是相当显著地禁止 PTEN 磷酸酶活动因此调制它的能力调整 PI3K 信号 transduction 串联。确实, RFP overexpression 在 AKT 激活上减轻调停 PTEN 的禁止的效果;相反,调停 RNAi 内长的 RFP 击倒提高 PTEN 的能力压制 AKT 激活。而且, PTEN 的调停 RFP 的 ubiquitination 禁止小道表示的 PTEN 依赖的激活并且也压制它的能力导致 apoptosis。我们的调查结果在控制 PTEN 表明调停 RFP 的 ubiquitination 的一个关键角色活动。 | James T Lee Jing Shan Jiayun Zhong Muyang Li Brenda Zhou Amanda Zhou Ramon Parsons Wei Gu | 2013 | Cell Research2013，23，4： | 5 |
| 3 | ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘 | Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza | 2012 | Neuroendocrinology2012，，2： | 3 |
| 4 | Peroxisome proliferator-activated receptorγB cell-specific-deficient mice have an impaired antibody response显示文摘 | Ramon S Bancos S Thatcher T H | 2012 | Immunology2012，189，10： | 1 |
| 5 | Nitration of biodiesel of waste oil: Nitrated biodiesel as a cetane number enhancer显示文摘 | LAUREANO C RAMON A SUSANA T | 2007 | Fuel2007，86，78： | 1 |
| 6 | Cas- cade position control of a single pneumatic artificial muscle mass system with hysteresis compensation 显示文摘 | Minh T V Tjahjowidodo T Ramon M | 2010 | Mechatronics2010，20，3： | 1 |
| 7 | Eff悬浮剂 ts of silymarin in alcoholic patient with cirrhosis of the liver: resuits of a controlled,doubled-blind randomized and multicenter trial 显示文摘 | Albert P Ramon P Miguel T | 1998 | Journal of Hepatology1998，28，： | 1 |
| 8 | Reconstruction of the maxilla with bone grafts supported by the buecal fat pad 显示文摘 | Vuillemin T Raveh J Ramon Y | 1988 | J Oral Maxillofac Surg1988，46，2： | 1 |
| 9 | Closing of adiponection receptors the mediate antidiabetic metabolic effects 显示文摘 | Yamauchi T Ramon J Ito Y | 2003 | Nature2003，423，6941： | 1 |
| 10 | Effects of silymarin inalcoholic patient with cinhosis of the liver : results of a con-trolled tdoubled-blind randomized and multicenter trial 显示文摘 | Albert P Ramon P Miguel T | 1998 | Journal of Hepatology1998，28，： | 1 |
| 11 | ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘 | Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza | 2012 | Neuroendocrinology2012，，2： | 1 |
| 12 | ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘 | Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza | 2012 | Neuroendocrinology2012，，2： | 1 |
| 13 | An iterated greedy al- gorithm for the flowshop scheduling problem with blocking显示文摘 | IMMA R RAMON C XAVIER T M | 2011 | Omega2011，39，3： | 1 |
| 14 | Effect of turgor on micromechanical and structural properties of apple tissue: A quantitative analysis显示文摘 | OEY M L VANSTREELS E DE BAERDEMAEKER J RAMON H HERTOG M L A T M NICOLA B | 2007 | Postharvest Biology and Technology2007，44，： | 1 |
| 15 | Influence of Fe^3+ on sintering and microstructure evolution of reaction sintered calcium hexaluminate 显示文摘 | Cristina D Ramon T | 1998 | Journal of European Ceramics Society1998，18，9： | 1 |
| 16 | Study of the authenticity of commercial wine yeast strains by molecular techniques 显示文摘 | FERNANDEZ-ESPINAR M T LOPEZ V RAMON D | 2001 | International Journal of Food Microbiology2001，70，12： | 1 |
| 17 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 1 |
| 18 | Kinetics of product ion and consumption of organic acids during alcoholic fermentation by Saccharomyces cerevisiae 显示文摘 | RAMON P F SEILLER T TAILLANDIER P | 1999 | Food Technol Bio1999，37，4： | 1 |
| 19 | Venture Capital in Spain by Stage of Development显示文摘 | PEREZ D G HOWARD V A | 2007 | Journal of Small Busi-ness Management2007，45，1： | 1 |
| 20 | Bicalutamide (Casodex) 150 mg as immediate therapy in patients with localized or locally advanced prostate cancer significantly reduces the risk of disease progression显示文摘 | M Wirth C Tyrrell M Wallace K.P Delaere M Sánchez-Chapado J Ramon J Hetherington F Pina C.F Heynes T.M Borchers T Morris A Stone | 2001 | Urology2001，，2： | 1 |
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