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| 1 | Ultrasonic vibration assisted tungsten inert gas welding of dissimilar magnesium alloys显示文摘The effects of ultrasonic vibration assisted(UVA) treatment on the microstructures and mechanical properties of MB3/AZ31 dissimilar magnesium(Mg) alloy joints were studied by microstructural characterization, micro-hardness testing and tensile testing. Results indicate that the welding pores are eliminated and coarse a-Mg grains of fusion zone are refined to 26 μm, owing to the acoustic streaming effect and cavitation effect induced by the UVA treatment with an optimal ultrasonic power of 1.0 kW.In addition, Mg_(17)Al_(12) precipitation phases are fine and uniformly distributed in the whole fusion zone of weldment. Micro-hardness of fusion zone of the Mg alloy joints increases to 53.5 HV after UVA process,and the maximum tensile strength with optimized UVA treatment increases to 263 MPa, which leads to fracture occurrence in the Mg alloy base plate. Eventually, it is experimentally demonstrated that robust MB3/AZ31 Mg alloy joints can be obtained by UVA process. | Fangzhou Yang Jie Zhou Rongrong Ding | 2018 | Journal of Materials Science & Technology2018，34，12： | 5 |
| 2 | H5N6禽流感病毒的基因起源、进化和流行显示文摘2014~2016年间对我国16个省份活禽市场的监测,共鉴定了3174份流感阳性样品,分离并测序了1135份禽流感病毒,分属于31种亚型。 | yuhai bi quanjiao chen qianli wang jianjun chen tao jin gary wong chuansong quan jun liu jun wu renfu yin lihua zhao mingxin li zhuang ding rongrong zou wen xu hong li huijun wang kegong tian guanghua fu yu huang alexander shestopalov shoujun li bing xu hongjie yu tingrong luo lin lu xun xu yang luo 刘映霞 史卫峰 刘翟 高福 | 2017 | 科学新闻2017，0，4： | 2 |
| 3 | Predictors of HIV and syphilis among men who have sexwith men in a Chinese metropolitan city:comparison ofrisks among students and non-students显示文摘 | ZHANG Lan DING Xianbin LU Rongrong | 2012 | PLOS ONE2012，7，37： | 1 |
| 4 | Genome-wide association analysis reveals genetic loci and candidate genes associated with intramuscular fat in Duroc pigs显示文摘Intramuscular fat(IMF) is a major meat-quality trait in pigs. The content of IMF is directly associated with the taste and flavor of pork. As a complex trait, there could be multiple genes affecting IMF content in pork. Genomewide association study is a powerful tool to detect genomic regions associated with phenotypic variations. The objectives of the present study were to identify or refine the positions of genomic regions affecting IMF, and to characterize candidate genes and pathways that may influence this trait. Of note, we identified a significant region in longissium dorsi muscle in a Duroc pig population for IMF content with Porcine SNP60 v2 Bead Chip. This region spans 1.24 Mb on chromosome 8 and had been identified as a quantitative trait locus for IMF in Pietrain, Large White, Landrace, and Leicoma pigs. In this region, eight SNPs were significantly associated with IMF content. Three genes proximal to these significant SNPs were considered candidate genes, including ZDHHC16, LOC102162218 and PCDH7. Our results confirm several previous findings and highlight several genes that may contribute to IMF variation in Duroc pigs. | Xingwang WANG Rongrong DING Jianping QUAN Linxue YANG Ming YANG Enqin ZHENG Dewu LIU Gengyuan CAI Zhenfang WU Jie YANG | 2017 | Frontiers of Agricultural Science and Engineering2017，4，3： | 1 |
| 5 | Improving the accuracy of genomic prediction for meat quality traits using whole genome sequence data in pigs显示文摘Background Pork quality can directly affect customer purchase tendency and meat quality traits have become valu-able in modern pork production.However,genetic improvement has been slow due to high phenotyping costs.In this study,whole genome sequence(WGS)data was used to evaluate the prediction accuracy of genomic best linear unbiased prediction(GBLUP)for meat quality in large-scale crossbred commercial pigs.Results We produced WGS data(18,695,907 SNPs and 2,106,902 INDELs exceed quality control)from 1,469 sequenced Duroc×(Landrace×Yorkshire)pigs and developed a reference panel for meat quality including meat color score,marbling score,L*(lightness),a*(redness),and b*(yellowness)of genomic prediction.The prediction accuracy was defined as the Pearson correlation coefficient between adjusted phenotypes and genomic estimated breeding values in the validation population.Using different marker density panels derived from WGS data,accuracy differed substantially among meat quality traits,varied from 0.08 to 0.47.Results showed that MultiBLUP outperform GBLUP and yielded accuracy increases ranging from 17.39%to 75%.We optimized the marker density and found medium-and high-density marker panels are beneficial for the estimation of heritability for meat quality.Moreover,we conducted genotype imputation from 50K chip to WGS level in the same population and found average concord-ance rate to exceed 95%and r^(2)=0.81.Conclusions Overall,estimation of heritability for meat quality traits can benefit from the use of WGS data.This study showed the superiority of using WGS data to genetically improve pork quality in genomic prediction. | Zhanwei Zhuang Jie Wu Yibin Qiu Donglin Ruan Rongrong Ding Cineng Xu Shenping Zhou Yuling Zhang Yiyi Liu Fucai Ma Jifei Yang Ying Sun Enqin Zheng Ming Yang Gengyuan Cai Jie Yang Zhenfang Wu | 2023 | Journal of Animal Science and Biotechnology2023，14，5： | 1 |
| 6 | High HIV prevalence detected in 2006 and 2007 among men who have sex with men in China's largest municipality:an alarming epidemic in Chongqing,China显示文摘 | Feng L Ding Xianbin Lu Rongrong | | 0，，01： | 1 |
| 7 | The SmNPR4-SmTGA5 module regulates SA-mediated phenolic acid biosynthesis in Salvia miltiorrhiza hairy roots显示文摘Phenolic acids are the main bioactive compounds in Salvia miltiorrhiza,which can be increased by salicylic acid(SA)elicitation.However,the specific molecular mechanism remains unclear.The nonexpresser of PR genes 1(NPR1)and its family members are essential components of the SA signaling pathway.Here,we report an NPR protein,SmNPR4,that showed strong expression in hairy root after SA treatment,acting as a negative moderator of SA-induced phenolic acid biosynthesis in S.miltiorrhiza(S.miltiorrhiza).Moreover,a basic leucine zipper family transcription factor SmTGA5 was identified and was found to interact with SmNPR4.SmTGA5 activates the expression of phenolic acid biosynthesis gene SmTAT1 through binding to the as-1 element.Finally,a series of biochemical assays and dual gene overexpression analysis demonstrated that the SmNPR4 significantly inhibited the function of SmTGA5,and SA can alleviate the inhibitory effect of SmNPR4 on SmTGA5.Overall,our results reveal the molecular mechanism of salicylic acid regulating phenolic acid biosynthesis in S.miltiorrhiza and provide new insights for SA signaling to regulate secondary metabolic biosynthesis. | Meiling Ding Bin Zhang Shuo Zhang RongRong Hao Yu Xia Pengda Ma Juane Dong | 2023 | Horticulture Research2023，10，5： | 0 |
| 8 | A pan-cancer analysis identifies SOAT1 as an immunological and prognostic biomarker显示文摘Sterol o-acyltransferase1(SOAT1)is an enzyme that regulates lipid metabolism.Nevertheless,the predictive value of SOAT1 regarding immune responses in cancer is not fully understood.Herein,we aimed to expound the predictive value and the potential biological functions of SOAT1 in pan-cancer.Raw data related to SOAT1 expression in 33 different types of cancer were acquired from The Cancer Genome Atlas(TCGA)and Genotype-Tissue Expression(GTEx)databases.SOAT1 expression was significantly increased in most cancers and showed a distinct correlation with prognosis.This enhanced expression of the SOAT1 gene was confirmed by evaluating SOAT1 protein expression using tissue microarrays.In addition,we found significant positive associations between SOAT1 expression levels and infiltrating immune cells,including T cells,neutrophils,and macrophages.Moreover,the co-expression analysis between SOAT1 and immune genes showed that many immune-related genes were increased with enhanced SOAT1 expression.A gene set enrichment analysis(GSEA)revealed that the expression of SOAT1 correlated with the tumor microenvironment,adaptive immune response,interferon signaling,and cytokine signaling.These findings indicate that SOAT1 is a potential candidate marker for predicting prognosis and a promising target for tumor immunotherapy in cancers. | YANGQING HUANG XINLAN ZHOU XIUFEN LI DAN HUANG ZHONG FANG RONGRONG DING | 2023 | Oncology Research2023，31，2： | 0 |
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