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| 1 | Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on virus replication and recurrent hepatitis显示文摘瞄准:决定 calcineurin 禁止者, cyclosporine 和 tacrolimus 的效果,在丙肝上,在病人的周期性的丙肝的病毒(HCV ) 复制和活动张贴肝移植。方法:在我们的中心为在 1999 和 2003 之间的联系 HCV 的肝肝硬化收到了肝移植的 107 个病人的一个队的数据回顾地被分析。浆液 HCV-RNA 的水平和周期性的肝炎的活动在作为主要抑制免疫力的代理人和没在移植以后在开始的 12 瞬间以内导致胆汁的复杂并发症的不那样类似的抑制免疫力的政体收到了 cyclosporine 或 tacrolimus 的 47 个病人之间被比较。结果:HCV-RNA 在移植以后在 3 瞬间以内增加了,但是 cyclosporine 组和 tacrolimus 组之间的差别是不足道的(在 12 瞬间的 P=0.49 ) 。另外,由浆液 transaminases 决定了的周期性的肝炎并且门发炎和纤维变性的组织学的分级没在 12 瞬间(P=0.34 ) 以后显示出有效差量。结论:一个主要抑制免疫力的代理人不在肝移植以后在感染 HCV 的病人影响周期性的肝炎的正式就职或严厉的 Cyclosporine 或 tacrolimus。 | Philip Hilgard Alisan Kahraman Nils Lehmann Cornelia Seltmann Susanne Beckebaum R Stefan Ross Hideo A Baba Massimo Malago Christoph E Broelsch Guido Gerken | 2006 | World Journal of Gastroenterology2006,12,5: | 235 |
| 2 | Hepatocellular carcinoma surveillance:An evidence-based approach显示文摘Hepatocellular carcinoma(HCC) makes up 75%-85% of all primary liver cancers and is the fourth most common cause of cancer related death worldwide. Chronic liver disease is the most significant risk factor for HCC with 80%-90% of new cases occurring in the background of cirrhosis. Studies have shown that early diagnosis of HCC through surveillance programs improve prognosis and availability of curative therapies. All patients with cirrhosis and high-risk hepatitis B patients are at risk for HCC and should undergo surveillance. The recommended surveillance modality is abdominal ultrasound(US) given that it is cost effective and noninvasive with good sensitivity. However, US is limited in obese patients and those with non-alcoholic fatty liver disease(NAFLD). With the current obesity epidemic and rise in the prevalence of NAFLD, abdominal computed tomography or magnetic resonance imaging may be indicated as the primary screening modality in these patients. The addition of alpha-fetoprotein to a surveillance regimen is thought to improve the sensitivity of HCC detection.Further investigation of serum biomarkers is needed. Semiannual screening is the suggested surveillance interval. Surveillance for HCC is underutilized and low adherence disproportionately affects certain demographics such as nonCaucasian race and low socioeconomic status. | Patrick S Harris Ross M Hansen Meagan E Gray Omar I Massoud Brendan M McGuire Mohamed G Shoreibah | 2019 | World Journal of Gastroenterology2019,25,13: | 31 |
| 3 | Liver iron transport显示文摘肝在铁新陈代谢起一个中央作用。它是为铁的主要存储地点并且也表示涉及铁运输和铁动态平衡的规定的分子的一个复杂范围。与肝的铁运输或规定联系的越来越多的基因被识别了。这些包括转铁蛋白受体(TFR1 并且 2 ) , ferrireductase (STEAP3 ) ,运输 ers 二价的金属 transporter-1 (DMT1 ) 和象 haemochromatosis 蛋白质, HFE 和 haemojuvelin (HJV ) 一样的 ferroportin (FPN ) ,它正在表明分子。许多也这些基因参予铁集中于肝的肽 hepcidin 的规章的小径。然而,我们开始仍然仅仅正在理解在肝之间的复杂相互作用熨运输和铁动态平衡。这评论在铁运输和铁动态平衡的规定构画出我们铁新陈代谢和他们的角色的分子的当前的知识。 | Ross M Graham Anita CG Chua Carly E Herbison John K Olynyk Debbie Trinder | 2007 | World Journal of Gastroenterology2007,13,35: | 12 |
| 4 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004,7,4: | 3 |
| 5 | A theory of the term structure of interest rates显示文摘 | Cox J C Ingersoll J E Ross S A | 1985 | Econometrica1985,53,2: | 2 |
| 6 | Pancreatic cancer显示文摘 | Theresa Pluth Yeo Ralph H Hruban Steven D Leach Robb E Wilentz Taylor A Sohn Scott E Kern Christine A Iacobuzio-Donahue Anirban Maitra Michael Goggins Marcia I Canto Ross A Abrams Daniel Laheru Elizabeth M Jaffee Manuel Hidalgo Charles J Yeo | 2002 | Current Problems in Cancer2002,,4: | 2 |
| 7 | Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis显示文摘 | Sophie A Jamal Ben Vandermeer Paolo Raggi David C Mendelssohn Trish Chatterley Marlene Dorgan Charmaine E Lok David Fitchett Ross T Tsuyuki | 2013 | The Lancet2013,,: | 2 |
| 8 | α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation显示文摘尽管为有类型 1 糖尿病的个人的小岛移植被显示了产出优异的血葡萄糖控制,它为长期的控制仍然保持不适当。这是部分,由于小岛损害和压力,那能导致贝它房间损失。过量 IL-1β 的抑制;活动可能最小化小岛损害,因此保存工作。IL-1 受体对手(IL-1Ra ) , IL-1β 的一个内长的禁止者;,保护小岛免受导致 cytokine 的坏死和 apoptosis 的伤害。因此,在 IL-1β 之间的不平衡;并且 IL-1Ra 可能影响到小岛的 allogeneic 和自体免疫的回答的功课。我们的组以前证明传播丝氨酸朊酶禁止者人 alpha-1-antitrypsin (hAAT ) ,以及 immunomodulatory 活动。在现在的学习,我们寻求了决定是否胰腺的小岛 hAAT 的 allograft 保护的活动被 IL-1Ra 调停感应。我们的结果证明 hAAT 在刺激巨噬细胞在 IL-1Ra 表示导致了 2.04 褶层增加并且 hAAT-pre-treated 小岛接枝在 IL-1Ra 抄本层次展出了 4.851 褶层增加,它与中等煽动性的侧面被联系。出人意料地,从 IL-1Ra-knockout 鼠标被孤立并且在 grafting 前与 hAAT 预先对待进野类型的鼠标的小岛在大概从渗入主机房间被导出的 intragraft IL-1Ra 表示产出增加,当主机的 hAAT 处理不在时的虽然。确实, hAAT-pre-treated 小岛产生了能在有教养的巨噬细胞导致 IL-1Ra 生产的 hAAT 免费的调节媒介。最后,我们证明 hAAT 为 p65 支持了不同 phosphorylation 和原子 translocation 模式,为 IL-1Ra 要求的一个关键抄写因素表示。 | Avishag Abecassis Ronen Schuster Galit Shahaf Eyal Ozeri Ross Green David E Ochayon Peleg Rider Eli C Lewis | 2014 | Cellular & Molecular Immunology2014,11,4: | 2 |
| 9 | Community integration显示文摘 | Ross E Mitchell Donald G Reid | 2000 | Annals of Tourism Research2000,,1: | 2 |
| 10 | Toxicity of pesticides to aquatic microorganisms: a review显示文摘 | Delorenzo M E Scott G I Ross P E | 2001 | Environ Toxicol Chem2001,20,1: | 2 |
| 11 | Longitudinal cohort analysis of lethal prostate cancer progression in transgenic mice 显示文摘 | Hsu C X Ross B D Chrisp C E | 1998 | J Urol1998,160,4: | 1 |
| 12 | Angiopoietinl protects the adult vasculature against plasma leakage 显示文摘 | Thurston G Rudge JS Ioffe E Zhou H Ross L Croll SD | 2000 | Nat Med2000,6,4: | 1 |
| 13 | Optical power and intelligent sensors显示文摘 | Ross J N Brignell J E | 1997 | Sensors and Actuators1997,,6: | 1 |
| 14 | Body and mind:The effects ofexercise,overweight,and physical health on psycho-logical well-being显示文摘 | Hayes D Ross C E | 1986 | Journal of Health and SocialBehavior1986,,27: | 1 |
| 15 | An intertemporal general equilibrium model of asset prices 显示文摘 | Cox J C Ingersoll J E Ross S A | 1985 | Econometrica1985,53,: | 1 |
| 16 | A theory of the term structure of interest rates显示文摘 | Cox J C Ingersoll J E Ross S A | 1985 | Econometrica1985,53,: | 1 |
| 17 | Investigation of simulated annealing,ant-colony optimization,and genetic algorithms for self-structuring antennas显示文摘 | COLEMAN C M ROTHWELL E J ROSS J E | 2004 | IEEE Transactions on Antennas and Propagation2004,52,4: | 1 |
| 18 | Electrospinning:the quest for nanofibers显示文摘 | ROSS S E | 2001 | International Fiber Journal2001,16,5: | 1 |
| 19 | Polymorphisms within the atrial natriuretic peptide gene in essential hypertension显示文摘 | Rutledge D Sun Y Ross E | 1995 | Hyperensions1995,13,: | 1 |
| 20 | Epidemiology of environmental tobacco smoke exposure 显示文摘 | Ross C Brownson Larry W Figgs Laura E Caisley | 2002 | Oncogene2002,,21: | 1 |