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| 1 | Neutrophil-lymphocyte ratio:A prognostic tool in patients with inhospital cardiac arrest显示文摘BACKGROUND In-hospital cardiac arrest(IHCA) portends a poor prognosis and survival to discharge rate. Prognostic markers such as interleukin-6, S-100 protein and high sensitivity C reactive protein have been studied as predictors of adverse outcomes after return of spontaneous circulation(ROSC); however; these variables are not routine laboratory tests and incur additional cost making them difficult to incorporate and less attractive in assessing patient's prognosis. The neutrophil-lymphocyte ratio(NLR) is a marker of adverse prognosis for many cardiovascular conditions and certain types of cancers and sepsis. We hypothesize that an elevated NLR is associated with poor outcomes including mortality at discharge in patients with IHCA.AIM To determine the prognostic significance of NLR in patients suffering IHCA who achieve ROSC.METHODS A retrospective study was performed on all patients who had IHCA with the advanced cardiac life support protocol administered in a large urban community United States hospital over a one-year period. Patients were divided into two groups based on their NLR value(NLR < 4.5 or NLR ≥ 4.5). This cutpoint was derived from receiving operator characteristic curve analysis(area under the curve = 0.66) and provided 73% positive predictive value, 82% sensitivity and42% specificity for predicting in-hospital death after IHCA. The primary outcome was death or discharge at 30 d, whichever came first.RESULTS We reviewed 153 patients with a mean age of 66.1 ± 16.3 years; 48% were female.In-hospital mortality occurred in 65%. The median NLR in survivors was 4.9(range 0.6-46.5) compared with 8.9(0.28-96) in non-survivors(P = 0.001). A multivariable logistic regression model demonstrated that an NLR above 4.55[odds ratio(OR) = 5.20, confidence interval(CI): 1.5-18.3, P = 0.01], older age(OR= 1.03, CI: 1.00-1.07, P = 0.05), and elevated serum lactate level(OR = 1.20, CI:1.03-1.40, P = 0.02) were independent predictors of death.CONCLUSION An NLR ≥ 4.5 may be a useful marker of increased risk of death in patients with IHCA. | Vishal H Patel Philip Vendittelli Rajat Garg Susan Szpunar Thomas LaLonde John Lee Howard Rosman Rajendra H Mehta Hussein Othman | 2019 | World Journal of Critical Care Medicine2019，8，2： | 5 |
| 2 | Acute Intramural Hematoma of the Aorta: A Mystery in Evolution显示文摘 | Arturo Evangelista Debabrata Mukherjee Rajendra H. Mehta Patrick T. O’Gara Rossella Fattori Jeanna V. Cooper Dean E. Smith Jae K. Oh Stuart Hutchison Udo Sechtem Eric M. Isselbacher Christoph A. Nienaber Linda A. Pape Kim A. Eagle | 2005 | Circulation2005，，8： | 2 |
| 3 | Chemopreventive and adjuvant therapeutic potential of pomegranate(Punica granatum) for human breast cancer显示文摘 | N D Kim Rajendra Mehta Weiping Yu | 2002 | Breast Cancer Res Treat2002，71，： | 1 |
| 4 | Association of Bleeding and In-Hospital Mortality in Black and White Patients With ST-Segment–Elevation Myocardial Infarction Receiving Reperfusion显示文摘 | Rajendra H. Mehta Lori Parsons Sunil V. Rao Eric D. Peterson | 2012 | Circulation2012，，14： | 1 |
| 5 | Predicting Death in Patients With Acute Type A Aortic Dissection显示文摘 | Rajendra H. Mehta Toru Suzuki Peter G. Hagan Eduardo Bossone Dan Gilon Alfredo Llovet Luis C. Maroto Jeanna V. Cooper Dean E. Smith William F. Armstrong Christoph A. Nienaber Kim A. Eagle | 2002 | Circulation: Journal of the American Heart Association2002，，2： | 1 |
| 6 | Reperfusion strategies for acute myocardial infarction in the elderly显示文摘 | Rajendra H. Mehta Christopher B. Granger Karen P. Alexander Eduardo Bossone Harvey D. White Michael H. Sketch | 2005 | Journal of the American College of Cardiology2005，，4： | 1 |
| 7 | Maleation of linear low-density polyethylene by reactive processing 显示文摘 | Norman G Gaylord Rajendra Mehta Doraisw amy R Mohan | 1992 | Journal of Applied Polymer Science1992，44，： | 1 |
| 8 | Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience显示文摘 | Santi Trimarchi Christoph A. Nienaber Vincenzo Rampoldi Truls Myrmel Toru Suzuki Rajendra H. Mehta Eduardo Bossone Jeanna V. Cooper Dean E. Smith Lorenzo Menicanti Alessandro Frigiola Jae K. Oh Michael G. Deeb Eric M. Isselbacher Kim A. Eagle | 2004 | The Journal of Thoracic and Cardiovascular Surgery2004，，1： | 1 |
| 9 | Maleation of linear low-density polyethylene by reactive processing 显示文摘 | Norman G Gaylord Rajendra Mehta Doraisamy R Mohan Vijay Kumar | 1992 | Journal of Applied Polymer Science1992，44，： | 1 |
| 10 | Trends and predictors of length of stay after primary percutaneous coronary intervention: A report from the CathPCI Registry显示文摘 | Chee Tang Chin William S. Weintraub David Dai Rajendra H. Mehta John S. Rumsfeld H. Vernon Anderson John C. Messenger Michael A. Kutcher Eric D. Peterson Ralph G. Brindis Sunil V. Rao | 2011 | American Heart Journal2011，，6： | 1 |
| 11 | Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer显示文摘 | Nam Deuk Kim Rajendra Mehta Weiping Yu | 2002 | Breast Cancer Research and Treatment2002，71，： | 1 |
| 12 | Peroxide - catalyzed grafting of maleie anhydride onto molten polyethylene in the presenee of polar organic compounds显示文摘 | NORMAN G GAYLORD RAJENDRA MEHTA | 1988 | J polym sei pol ehem1988，26，4： | 1 |
| 13 | Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granaturn) for human breast cancer显示文摘 | Nam Deuk Kim Rajendra Mehta Weiping Yu | 2002 | Breast Cancer Research and Treatment2002，71，： | 1 |
| 14 | Peroxide-catalyzed grafting of maleic anhydride onto molten polyethylene in the presence of polar organic compounds显示文摘 | Norman G Gaylord Rajendra Mehta | 1988 | Journal of Applied Polymer Science1988，，6： | 1 |
| 15 | Maleation of linear low-density polyethylene by reactive processing显示文摘 | Norman G Gaylord Rajendra Mehta Doraiswamy R Mohan | 1992 | Journal of Applied Polymer Science1992，44，： | 1 |
| 16 | Estrogen receptor‐β protects against colitis‐associated neoplasia in mice显示文摘 | Diana Saleiro Genoveva Murillo Richard V. Benya Marc Bissonnette John Hart Rajendra G. Mehta | 2012 | Int J Cancer2012，，11： | 1 |
| 17 | High density polyethylene-gmaleic anhydride preparation in presence of electron donors显示文摘 | Norman G Gaylord Rajendra Mehta Vijay Kumar | 1989 | Journal of Applied Polymer Science1989，38，2： | 1 |
| 18 | Cancer Chemoprevention by Natural Products: How Far Have We Come?显示文摘 | Rajendra G. Mehta Genoveva Murillo Rajesh Naithani Xinjian Peng | 2010 | Pharmaceutical Research2010，，6： | 1 |
| 19 | Red versus white thrombi in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: clinical and angiographic outcomes显示文摘 | Alexandre S. Quadros Eduardo Cambruzzi Juliana Sebben Renato B. David Anibal Abelin Dulce Welter Rogério Sarmento-Leite Rajendra H. Mehta Carlos A. Gottschall Renato D. Lopes | 2012 | American Heart Journal2012，，： | 1 |
| 20 | Comparison of aortic dissection in patients with and without Marfan’s syndrome (results from the International Registry of Aortic Dissection)显示文摘 | James L Januzzi Firas Marayati Rajendra H Mehta Jeanna V Cooper Patrick T O’Gara Udo Sechtem Eduardo Bossone Arturo Evangelista Jae K Oh Christoph A Nienaber Kim A Eagle Eric M Isselbacher | 2004 | The American Journal of Cardiology2004，，3： | 1 |
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