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| 1 | 幽门螺杆菌感染处理的当前观念——MaastrichtⅢ共识报告显示文摘名词缩写欧洲幽门螺杆菌研究小组:European Helicobacter Study Group,EHSG胃食管反流病:gastro-esophageal reflux disease。 | P Malfertheiner F Megraud C O'Morain F Bazzoli E El-Omar D Graham R Hunt T Rokkas N Vakil EJ Kuipers 朱琦 | 2007 | 胃肠病学2007，12，3： | 15 |
| 2 | Risk of colorectal neoplasm in patients with acromegaly: A meta-analysis显示文摘AIM: To examine the risk of colorectal neoplasm in acromegalic patients by meta-analyzing all relevant controlled studies. METHODS: Extensive English language medical literature searches for human studies, up to December 2007, were performed using suitable keywords. Pooled estimates [odds ratio (OR) with 95% confidence intervals (CI)] were obtained using either the fixed or random-effects model as appropriate. Heterogeneity between studies was evaluated with the Cochran Q test whereas the likelihood of publication bias was assessed by constructing funnel plots. Their symmetry was estimated by the adjusted rank correlation test. RESULTS: For hyperplastic polyps the pooled ORs with 95% CI were 3.557 (2.587-4.891) by fixed effects model and 3.703 (2.565-5.347) by random effects model. The Z test values for overall effect were 7.81 and 6.984, respectively (P < 0.0001). For colon adenomas the pooled ORs with 95% CI were 2.486 (1.908-3.238) (fixed effects model) and 2.537 (1.914-3.364) (random effects model). The Z test values were 6.747 and 6.472, respectively (P < 0.0001). For colon cancer the pooled OR with 95% CI was identical for both fixed and random effects model (OR, 4.351; 95% CI, 1.533-12.354; Z = 2.762, P = 0.006]. There was no significant heterogeneity and no publication bias in all the above meta-analyses. CONCLUSION: Acromegaly is associated with an increased risk of colorectal neoplasm. | Theodoros Rokkas Dimitrios Pistiolas Panos Sechopoulos Georgios Margantinis Georgios Koukoulis | 2008 | World Journal of Gastroenterology2008，14，22： | 8 |
| 3 | Helicobacter pylori,gastric microbiota and gastric cancer relationship:Unrolling the tangle显示文摘Helicobacter pylori infection(Hp-I)represents a typical microbial agent intervening in the complex mechanisms of gastric homeostasis by disturbing the balance between the host gastric microbiota and mucosa-related factors,leading to inflammatory changes,dysbiosis and eventually gastric cancer.The normal gastric microbiota shows diversity,with Proteobacteria[Helicobacter pylori(H.pylori)belongs to this family],Firmicutes,Actinobacteria,Bacteroides and Fusobacteria being the most abundant phyla.Most studies indicate that H.pylori has inhibitory effects on the colonization of other bacteria,harboring a lower diversity of them in the stomach.When comparing the healthy with the diseased stomach,there is a change in the composition of the gastric microbiome with increasing abundance of H.pylori(where present)in the gastritis stage,while as the gastric carcinogenesis cascade progresses to gastric cancer,the oral and intestinal-type pathogenic microbial strains predominate.Hp-I creates a premalignant environment of atrophy and intestinal metaplasia and the subsequent alteration in gastric microbiota seems to play a crucial role in gastric tumorigenesis itself.Successful H.pylori eradication is suggested to restore gastric microbiota,at least in primary stages.It is more than clear that Hp-I,gastric microbiota and gastric cancer constitute a challenging tangle and the strong interaction between them makes it difficult to unroll.Future studies are considered of crucial importance to test the complex interaction on the modulation of the gastric microbiota by H.pylori as well as on the relationships between the gastric microbiota and gastric carcinogenesis. | Christos Liatsos Apostolis Papaefthymiou Nikolaos Kyriakos Michail Galanopoulos Michael Doulberis Marios Giakoumis Evangelia Petridou Christos Mavrogiannis Theodore Rokkas Jannis Kountouras | 2022 | World Journal of Gastrointestinal Oncology2022，14，5： | 6 |
| 4 | Gastric Cancer: Epidemiologic Aspects显示文摘 | Carlos A. González Núria Sala Theodore Rokkas | 2013 | Helicobacter2013，，： | 4 |
| 5 | Relationship Between Helicobacter pylori Infection and Esophageal Neoplasia: A Meta-analysis显示文摘 | Theodoros Rokkas Dimitrios Pistiolas Panos Sechopoulos Ioannis Robotis Georgios Margantinis | 2007 | Clinical Gastroenterology and Hepatology2007，，12： | 3 |
| 6 | 勃起功能障碍患者中心血流动力学对心血管事件的预测作用显示文摘本研究调查中心血流动力学是否能够超越传统危险因素预测勃起功能障碍(erectile dysfunction,ED)患者主要不良心血管事件(major adverse cardiovascular events,MACE)的发生。方法:分析398例(平均年龄56年)ED但无确诊的心血管病患者的MACE与主动脉压和增强指数(augmentation index,AIx)之间的关系。 | Vlachopoulos C Ioakeimidis N Rokkas K Angelis A Terentes-Printzios D Kratiras Z Georgakopoulos C Tousoulis D 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，12： | 3 |
| 7 | Nutritional Status,Sarcopenia and the Importance of Prehabilitation of Gastrointestinal Tumor Patients:a Surgical Point of View显示文摘Background Surgery may be the field of healthcare where malnutrition and sarcopenia have their greatest impact on patient morbidity and mortality.However,there are limited data on the nutritional status of surgical patients and the effects of prehabilitation on the outcomes of surgery.Methods A prospective analysis was conducted on all patients surgically-treated for malignant gastrointestinal tumors at St.John Hospital during a two-year period.The patient’s gender,age,body weight,height,BMI and weight loss were registered,then a risk score was determined by the MUST survey.Measurement of the triceps and thigh skin-fold thickness and the circumference of the upper arm and thigh were done to calculate muscle area and muscle index,respectively.The body composition was assessed using an OMRON-BF511 device.Muscle function was evaluated based on hand clamping force measurement and activity tests.Patients who were diagnosed as being at-risk received preoperative prehabilitation,which included physiotherapy and nutritional therapy.Results A total of 231 patients(133 males/98 females)were analyzed.They had a mean age of 68.9 years(18~98).Seventy-four patients(32%)lost weight,with an average loss of 7 kilograms(3~15 kg).Anthropometric data showed an average upper-arm circumference of 27.4 cm(14.3~38.1)and thigh circumference of 44.7 cm(19.3~60.1),so the median muscle index was 1.29.The mean BMI was 26,which is above normal,and the elevated BMI was consistent documented in each patient subgroup stratified by age and tumor type.A body composition analysis was performed for 75 patients(44 male/31 female),who had a median age of 68(37~88 y).The average BMI of these patients was 25.7 y and their average MUST score was 1.12.The total body fat percentage(of the total body mass)was 29.5%,total muscle was 30.1%and visceral fat was 10%.Thirty patients(40%)had sarcopenia,with a mean BMI of 28.7,fat comprising 34.2%of the body mass,visceral-fat 11%,and muscle 27.1%,and their median MUST score was 1.23.Patients who received preoperative training(physiotherapy)showed improvements in physical function ranging from 12%~33%.Conclusion Gastrointestinal tumor patients have a higher than normal BMI regardless of age or tumor type.Patients with sarcopenia show measurable improvement after two weeks of prehabilitation. | Péter Lukovich Ákos Nagy Bianka Barok Borbála Csiba Ram Rokka Balázs Pőcze | 2020 | Journal of Nutritional Oncology2020，5，3： | 2 |
| 8 | Helicobacter pylori and Gastrointestinal Malignancies显示文摘 | Marino Venerito Riccardo Vasapolli Theodoros Rokkas Peter Malfertheiner | 2015 | Helicobacter2015，，： | 2 |
| 9 | Determination of Fusari-um mycotoxins beauvericin and enniatins ( A, Ai , B, Bi) in eggsof laying hens using liquid chromatography-tandem mass spec-trometry (LC-MS/MS) 显示文摘 | Jestoi M Rokka M Jarvenpaa E | 2009 | Food Chemistry2009，115，3： | 1 |
| 10 | Effect of specific colostral antibodies and selected lactobacilli on the adhesion of Helicobacter pylori on AGS cells and the Helicobacter-induced IL-8 production显示文摘 | Rokka S Myllykangas S Joutsjoki V | 2008 | Scandinavian Journal of Immunology2008，68，3： | 1 |
| 11 | Bronchoalveolar lavage findings in a young adult with idiopathic pulmonary haemosiderosis and coeliac disease显示文摘 | Bouros D Panagou P Rokkas T | 1994 | Eur Respir J1994，7，： | 1 |
| 12 | Simultaneous Determination of Four Coccidiostats in Eggs and Broiler Meat: Vallidation of an LC - MS/MS Method 显示文摘 | ROKKA M Pehonen K | 2006 | Food Additives Contaminants2006，23，： | 1 |
| 13 | The association between CagA status and the development of esophagitis after the eradication ofHelicobacterpylori显示文摘 | Rokkas T Ladas SD Triantafyllou K | 2001 | Anm J Med2001，110，9： | 1 |
| 14 | Population differ- ences concerning TNF-a gene polymorphisms in gastric carcino- genesis based on meta-analysis显示文摘 | Rokkas T Sechopoulos P Pistiolas D | 2014 | Ann Gastroentcrol2014，27，2： | 1 |
| 15 | The association between CagA status and the development ofesophagitis after the eradication of Helicobacterpylori显示文摘 | Ladas SD Triantafyllou K | 2001 | Am J Med2001，110，9： | 1 |
| 16 | Angiotensin converting enzyme inhibitory peptides derived from bovine milk proteins显示文摘 | Pihlanto-Leppala A Rokka T Korhonen H | 1998 | International Dairy Journal1998，8，： | 1 |
| 17 | Protecting Probiotic Bacteria by Microencapsulation: Challenges for Industrial Applications 显示文摘 | ROKKA S RANTAMAKI P | 2010 | European Food Research and Technology2010，231，1： | 1 |
| 18 | Gastric cancer: clini- cal aspects, epidemiology and molecular background 显示文摘 | Bornschein J Rokkas T Selgrad M | 2011 | Helico- bacter2011，16，1： | 1 |
| 19 | Hypothermic cardiopulmonary bypass and circulatory arrest for operations on the descending thoracic and thoracoabdominal aorta显示文摘 | Kouchoukos NT Masetti P Rokkas CK | 2002 | Ann Thorac Surg2002，74，： | 1 |
| 20 | Helicobaeter pylori infection and gastric juice vitamin C levels impact of eradication 显示文摘 | Rokkas T Papatheodorous G Karameris A | 1995 | Dig Dis Sci1995，40，： | 1 |
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