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| 1 | Influence of silane on corrosion resistance of magnesium alloy AZ31 with thermally sprayed aluminum coatings显示文摘Aluminum coatings on Mg alloy AZ31 were fabricated using the thermal spraying technique, and then sealed with silane.The surface morphology and chemical groups were discerned using scanning electron microscopy and examined using Fourier transformation infrared spectroscopy, respectively.The salt fog tests and the potentiodynamic electrochemical technique were applied to evaluate the influence of silane on corrosion of the AZ31 alloy with aluminum coatings.The results showed that the corrosion resistance of the aluminum-coated AZ31 alloy was superior to that of the substrate.The aluminum coating sealed with various silane layers led to a further increase in the corrosion resistance of the alloy.Double silane layers were more corrosion-resistant than the single one.Also, it was no longer significant for more than two silane layers to improve the corrosion resistance.It implied that the optimum choice for silane treatment on the aluminum coatings was two layers. | ZENG Rongchang CHEN Jun KUANG Jun ZHANG Jin WANG Ying | 2010 | Rare Metals2010，29，2： | 7 |
| 2 | In vitro and in vivo biodegradation and biocompatibility of an MMT/BSA composite coating upon magnesium alloy AZ31显示文摘The performance of biodegradable magnesium alloy requires special attention to rapid degradation and poor biocompatibility, which can cause the implant to fail. Here, a sodium montmorillonite(MMT)/bovine serum albumin(BSA) composite coating was prepared upon magnesium alloy AZ31 via hydrothermal synthesis, followed by dip coating. We evaluated the surface characterization and corrosion behavior in vitro, and the biocompatibility in vitro and in vivo. Biodegradation progress of the MMT-BSA coated Mg pieces was examined through hydrogen evolution, immersion tests, and electrochemical measurements in Hank’s solution. In vitro biocompatibility studies were evaluated via hemolysis tests, dynamic cruor time tests, platelet adhesion, MTT testing and live-dead stain of osteoblast cells(MC3 T3-E1). It was found that the MMT-BSA coating had good corrosion resistance and a marked improvement in biocompatibility in comparison to bare Mg alloy AZ31. in vivo studies were carried out in rat model and the degradation was characterized by computed tomography scans. Results revealed that the MMT-BSA coated Mg alloy AZ31 implants maintained their structural integrity and slight degradation after 120 d of post-implantation. A100% survival rate for the rats was observed with no obvious toxic damages on the organs and tissues.Additionally, we proposed a sound coating formation mechanism. Considering the good corrosion protection and biocompatibility, the MMT-BSA coated Mg alloy AZ31 is a promising candidate material for biomedical implants. | Jian Wang Lanyue Cui Yande Ren Yuhong Zou Jinlong Ma Chengjian Wang Zhongyin Zheng Xiaobo Chen Rongchang Zeng Yufeng Zheng | 2020 | Journal of Materials Science & Technology2020，47，12： | 7 |
| 3 | Corrosion behavior of TiO, coating on magnesium alloy AM60 in Hank's solution显示文摘 | Zeng Rongchang Dietzel W Chen jun | 2008 | Key Engineering Materials2008，，： | 1 |
| 4 | Characterization and wear resistance of macro-arc oxidation coating on magnesium alloy AZ91 in simulated body fluids 显示文摘 | CHEN Jun ZENG Rongchang HUANG Weijiu ZHENG Ziqing WANG Zhenlin WANG Jun | 2008 | Transactions of Nonferrous Metals Society of China2008，，18： | 1 |
| 5 | Electrochemical behavior of magnesium alloys in simulated body fluids显示文摘 | Zeng Rongchang Chen Jun Dietzel W | 2007 | Trans Nonferrous Met Soc China2007，17，1： | 1 |
| 6 | In- travenous moxifloxacin in routine hospital treatment of respiratory tract infections in China: results of a multi- center, noninterventional study显示文摘 | Rongchang Chen Wenjiang Ma Xuezhong Yu | 2011 | International Journal of General Medicine2011，，： | 1 |
| 7 | Expert consensus on acute exacerbation of chronic obstructive pulmonary disease in the People’s Republic of China显示文摘 | CAI Baiqiang CAI Shaoxi CHEN Rongchang | 2014 | International Journal of Chronic Obstructive Pulmonary Disease2014，，9： | 1 |
| 8 | A genetic algorithm for planning travel route with minimum transportation carbon footprint 显示文摘 | Chen Rongchang Chen Chienting Li Jyunyang | 2012 | Information and Business Intelligence2012，268，2： | 1 |
| 9 | Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital显示文摘Acinetobacter baumannii is a frequent cause of nosocomial infections.Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A.baumannii(CRAB)clone ST457 and assess the effectiveness of patient screening for outbreak control.CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019.Fourteen CRAB isolates were assigned to ST457,and 13 belonged to an outbreak clone,as determined by phylogenomic analysis.Strict patient screening was started at the respiratory intensive care unit on May 2019,through which a ST457-positive patient transferred from the intensive care unit was detected.No positive patients were detected within 3months onwards.The results of this study highlight the importance of rigorous infection prevention and control measures,combined with patient screening,in controlling the CRAB outbreak. | Chuqiu Zhang Tingting Xu Yang Ji Wenping Zheng Jingsong Wu Yuemei Lu Huiping Li Rongchang Chen Chen Qiu Kai Zhou | 2021 | Infectious Microbes & Diseases2021，3，4： | 1 |
| 10 | Character of diaphragm compound muscle action potential and phrenic nerve conduction time in patients with obstructive sleep apnea-hypopnea syndrome显示文摘BACKGROUND: Both hypoxia and carbon dioxide retention can damage phrenic nerve and muscle conduction, as well as diaphragm function. Diaphragm compound muscle action potential and phrenic nerve conduction time are reliable indicators for measuring phrenic nerve and diaphragm function. OBJECTIVES: To verify the hypothesis that changes of phrenic nerve conduction time (PNCT) and diaphragm compound muscle action potential (CMAP) in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients might contribute to the decline of phrenic nerve and diaphragm function. PNCT and CMAP were measured with multipair esophageal electrodes combined with unilateral magnetic stimulation. DESIGN, TIME AND SETTING: Case controlled study. The experiment was carried out in Guangzhou Institute of Respiratory Disease, Guangzhou Medical College, from June 2005 to April 2006. PARTICIPANTS: Twenty seven OSAHS patients and eight primary snoring subjects from Guangzhou Institute of Respiratory Disease, Guangzhou Medical College were recruited and all subjects were diagnosed by polysomnography (PSG). Sixteen healthy, non-snoring subjects in the hospital for medical examination during the same time period were selected as the control group. METHODS: Esophageal electrodes, made by Guangzhou Institute of Respiratory Disease, combined with unilateral magnetic stimulation, were used to measure PNCT and CMAP of all subjects. PNCT was defined as the time from stimulation artifact to the onset of CMAP and diaphragm CMAP amplitude was measured from peak to peak. Oxygen desaturation index and apnea-hypopnea index were measured using PSG, and their relevance to PNCT and CMAP were analyzed. PNCT and CMAP in five OSAHS patients were repeatedly measured after effective nasal continuous positive airway pressure treatment for more than 2 months. MAIN OUTCOME MEASURES: (1) PNCT and diaphragm CMAP of subjects in each group. (2) Relevance of oxygen desaturation index and apnea-hypopnea index to PNCT and CMAP. (3) Changes of PNCT and CMAP of OSAHS patients before and after treatment. RESULTS: All subjects were included in the analyzed results. (1) PNCT of the OSAHS group was significantly longer compared to that of the control and primary snore groups, while CMAP of the OSAHS group was significantly lower (P < 0.05). (2) PNCT and CMAP recorded from both sides correlated significantly with oxygen desaturation index and with apnea-hypopnea index (P < 0.01). (3) PNCT shortened significantly after effective nasal continuous positive airway pressure treatment for more than 2 months ( P < 0.05). CONCLUSION: Prolongation of PNCT and decrease of CMAP might contribute to the decline of phrenic nerve and diaphragm function caused by repeated nocturnal hypoxia and carbon dioxide retention. The impairment of the phrenic nerve might also decrease diaphragm function. | Yuhong HOU Rongchang Chen Jinbing Pan Yuanming Luo Nanshan Zhong | 2008 | Neural Regeneration Research2008，3，5： | 0 |
| 11 | Non-escaping frost tolerant QTL linked genetic loci at reproductive stage in six wheat DH populations显示文摘Reproductive stage frost poses a major constraint for wheat production in countries such as Australia.However,little progress has been made in identifying key genes to overcome the constraint.In the present study,a severe frost event hit two large-scale field trials consisting of six doubled haploid(DH)wheat populations at reproductive stage(young microspore stage)in Western Australia,leading to the identification of 30 robust frost QTL on 17 chromosomes.The major 18 QTL with the phenotype variation over 9.5%were located on 13 chromosomes including 2 A,2 B,2 D,3 A,4 A,4 B,4 D,5 A,5 D,6 D,7 A,7 B and7 D.Most frost QTL were closely linked to the QTL of anthesis,maturity,Zadok stages as well as linked to anthesis related genes.Out of those,six QTL were repetitively detected on the homologous regions on 2 B,4 B,4 D,5 A,5 D,7 A in more than two populations.Results showed that the frost damage is associated with alleles of Vrn-A1 a,Vrn-D1 a,Rht-B1 b,Rht-D1 b,and the high copy number of Ppd-B1.However,anthesis QTL and anthesis related genes of Vrn-B1 a and Ta FT3-1 B on chromosomes 5 B and 1 B did not lead to frost damage,indicating that these early-flowering phenotype related genes are compatible with frost tolerance and thus can be utilised in breeding.Our results also indicate that wild-type alleles Rht-B1 a and Rht-D1 a can be used when breeding for frost-tolerant varieties without delaying flowering time. | Jingjuan Zhang MD Shahidul Islam Yun Zhao Masood Anwar Zaid Alhabbar Maoyun She Rongchang Yang Angela Juhasz Guixiang Tang Jiansheng Chen Hang Liu Yanjie Jiang Shengnan Zhai Xin Hu Junkang Rong Yingquan Zhang Yebo Qin Qier Liu Zitong Yu Yujuan Zhang Sadegh Balotf Mirza Dowla Sonia Afrin Nandita Roy Md Resad Mallik Md Atik Us Saieed Shanjida Rahman Nigarin Sultana Sarah Al-Sheikh Ahmed Chris Florides Kefei Chen Darshan Sharma Nathan Height Ben Biddulph Meiqin Lu Jorge EMayer Wujun Ma | 2022 | The Crop Journal2022，10，1： | 0 |
| 12 | Didymin attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress显示文摘Objective:This study was designed to investigate the protective effects of didymin(Did)on doxorubicin(DOX)-induced cardiotoxicity.Methods:After pretreatment with Did(2,4,8 mg/kg intraperitoneal i.p.)for 7 d,the male C57 mice were injected with single dose of DOX(20 mg/kg i.p.).The cardioprotective effect of Did was observed on the 7th day after DOX treatment.Results:DOX delayed body growth and caused cardiac tissue injury,oxidative stress,and mitochondrial dysfunction.Similar experiments in H9C2 cardiomyocytes showed that DOX reduced cell viability,increased generation of reactive oxygen species(ROS)and fragmentation of DNA,decreased mitochondrial membrane potential,and induced cardiomyocyte apoptosis.However,all of these adverse effects were suppressed by Did pretreatment.Did increased protein expression of glutamate-L-cysteine ligase catalytic subunit(GCL),heme oxygenase 1(HO-1),and nuclear factor erythroid 2-related factor 2(Nrf2).Besides,Did also induced activation of PI3K/AKT.Conclusion:These findings indicated Did prevented DOX-induced cardiac injury and apoptosis via activating PI3K/AKT/Nrf2 signaling pathway. | Rongchang Chen Guibo Sun Lijiao Xu Xu Zhang Wenying Zeng Xiaobo Sun | 2022 | Chinese Herbal Medicines2022，14，1： | 0 |
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