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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Experimen tal Investigation of Heat Transfer in Grinding显示文摘 | Rowe W B Black S C E Mills B | 1995 | CIRP Annals- Manufacturing Technology1995，44，1： | 1 |
| 3 | Temperature Control in cBN Grinding显示文摘 | Rowe W B Black S C E Mills B | 1996 | Advanced Manufaeturing Technology1996，，12： | 1 |
| 4 | Is the current BMI obesity classification appropriate for black and white post- menopausal women? 显示文摘 | EVANS E M ROWE D A GACETTE S B etal | 2006 | Int J Obes (Lond)2006，30，5： | 1 |
| 5 | Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4 显示文摘 | ROW E C BROWN S A STACHULSKI A V | 2006 | Org Biomol Chem2006，4，10： | 1 |
| 6 | Identification of host-specific colonisation factors of Salmonella enterica serovar Typhimurium 显示文摘 | Morgan E Campbell J D Rowe S C | 2004 | Mol Microbiol2004，54，： | 1 |
| 7 | The unsatisfactory thin- Prep pap test missed opportunity for disease detection? 显示文摘 | Bentz J S Rowe L R Gopez E V | 2002 | Am J Clin Patho12002，117，3： | 1 |
| 8 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 9 | Experimental investigation of heat transfer in grinding显示文摘 | Rowe W B Black S C E Qi H S | 1995 | Annals of the CIIIP1995，44，1： | 1 |
| 10 | A distinct lineage of influenza A virus from bats显示文摘 | Tong S Li Y Rivailler P Conrardy C Castillo D A Chen L M Recuenco S Ellison J A Davis C T York I A Turmelle A S Moran D Rogers S Shi M Tao Y Weil M R Tang K Rowe L A Sammons S Xu X Frace M Lindblade K A Cox N J Anderson L J Rupprecht C E Donis R O | 2012 | PANS2012，109，11： | 1 |
| 11 | Effect of PEGylation on the solution conformation of antibody fragments显示文摘 | Lu Y Harding S E Turner A Smith B Athwal D S Grossmann J G Davis K G Rowe A J | 2008 | Journal of Pharmaceutical Sciences2008，97，6： | 1 |
| 12 | Grinding temperatures and energy partitioning显示文摘 | ROWE W B BLACK S C E MILLS B | | 0，，1960： | 1 |
| 13 | A simplified approach to control of thermal damage in grinding 显示文摘 | Rowe B W Morgan M N Black S C E | 1996 | Annals of the CIRP1996，45，1： | 1 |
| 14 | Essential role for the major autolysin in the fibronectin-binding protein-mediated Staphylococcus aureus biofilm phenotype显示文摘 | Houston P Rowe S E Pozzi C | 2011 | Infect Immun2011，79，3： | 1 |
| 15 | The Impact of Information Technology on the Organization of Economic Activity : the 'Move to the Middle' Hypothesis显示文摘 | Clemons E K Reddi S P Row M C | 1993 | Journal of Management Information System1993，10，2： | 1 |
| 16 | Use of ^3H/^3He ages to evaluate and improve groundwater flow models in a complete buried-valley aquifer 显示文摘 | Sheets R A Bair E S Rowe G L | 1998 | Water Resources Research1998，34，： | 1 |
| 17 | Molecularepizootiology and evolution of the glycoprotein andnon-virion protein genes of infectious hematopoieticnecrosis virus,a fish rhabdovirus 显示文摘 | Nichol S T Rowe J E Winton J R | 1995 | VirusResearch1995，38，23： | 1 |
| 18 | PGC-1[alpha] promotes recovery after acute kidney injury during systemic inflammation in mice显示文摘 | Tran Mei Tam Denise Bardia Amit Bhasin Manoj Rowe Glenn C Kher Ajay Zsengeller Zsuzsanna K Akhavan-Sharif M Reza Khankin Eliyahu V Saintgeniez Magali David Sascha Burstein Deborah Karumanchi S Ananth Stillman Isaac E Arany Zoltan Parikh Sa | 2011 | Journal of Clinical Investigation2011，，10： | 1 |
| 19 | Experimental investigation of heat transfer in grinding显示文摘 | Rowe W B Black S C E Mills B | 1995 | Annals of the CIRP1995，44，1： | 1 |
| 20 | Validation of thermal properties in grinding 显示文摘 | Rowe W B Morgan M N Black S C E | 1998 | Annals of the CIRP1998，47，1： | 1 |
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