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| 1 | Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats显示文摘It remains unclear whether autophagy affects hippocampal neuronal injury in vascular dementia. In the present study, we investigated the effects of autophagy blockade on hippocampal neuronal injury in a rat model of vascular dementia. In model rats, hippocampal CA1 neurons were severely damaged, and expression of the autophagy-related proteins beclin-1, cathepsin B and microtubule-associated protein 1 light chain 3 was elevated compared with that in sham-operated animals. These responses were suppressed in animals that received a single intraperitoneal injection of wortmannin, an autophagy inhibitor, prior to model establishment. The present results confirm that autophagy and autophagy-related proteins are involved in the pathological changes of vascular dementia, and that inhibition of autophagy has neuroprotective effects. | Bin Liu Jing Tang Jinxia Zhang Shiying Li Min Yuan Ruimin Wang | 2014 | Neural Regeneration Research2014，9，13： | 25 |
| 2 | Runoff reduction due to environmental changes in the Sanchuanhe river basin显示文摘Recently,runoff in many river basins in China has been decreasing.Therefore,the role that climate change and human activities are playing in this decrease is currently of interest.In this study,we evaluated an assessment method that was designed to quantitatively separate the effects of climate change and human activities on runoff in river basins.Specifically,we calibrated the SIMHYD rainfall runoff model using naturally recorded hydro-meteorologic data pertaining to the Sanchuanhe River basin and then determined the effects of climate change and human activities on runoff by comparing the estimated natural runoff that occurred during the period in which humans disturbed the basin to the runoff that occurred during the period prior to disturbance by humans.The results of this study revealed that the SIMHYD rainfall runoff model performs well for estimating monthly discharge.In addition,we found that absolute runoff reductions have increased in response to human activities and climate change,with average reductions of 70.1% and 29.9% in total runoff being caused by human activities and climate change,respectively.Taken together,the results of this study indicate that human activities are the primary cause of runoff reduction in the Sanchuanhe River basin. | Guoqing WANG Jianyun ZHANG Ruimin HE Naiqian JIANG Xin'ai JING | 2008 | International Journal of Sediment Research2008，23，2： | 9 |
| 3 | Historical Transformation of China's Agriculture" Productivity Changes and Other Key Features显示文摘 | Shouying Liu Ruimin Wang Guang Shi | 2018 | China & World Economy2018，26，1： | 9 |
| 4 | Ternary Organic Solar Cells Based on Two Non-fullerene Acceptors with Complimentary Absorption and Balanced Crystallinity显示文摘Summary of main observation and conclusion The ternary blend structure has been demonstrated as an effective approach to increase the power conversion efficiency of organic solar cells.An effective approach to enhance the power conversion efficiency of ternary solar cells is based on two non-fullerene acceptors with complimentary absorption range and balanced crystallinity.In this work,we have introduced a high crystallinity small-molecule acceptor,named C8IDTT-4CI with appropriate alkyl side chains into a low crystalline blend of conjugated polymer donor PBDT-TPD and fused-ring electron acceptor ITIC-4F.A ternary device based on the blend PBDT-TPD:1TIC-4F:C81DTT-4CI exhibits a best power conversion efficiency of 9.51%with a simultaneous improvement of the short-circuit current density to 18.76 mA-cm^-2 and the fill factor up to 67.53%.The absorption onset for C8IDTT-4CI is located at 900 nm,so that the well complementary light absorption is beneficial to the photocurrent.In addition,the existence of high crystallinity C8IDTT-4CI in the ternary device is found helpful to modulate crystallinity,improve heterojunction morphologies and stacking structure,therefore to realize higher charge mobility and better performance. | Lan Xie Chen Yang Ruimin Zhou Zhen Wang Jianqi Zhang Kun Lu Zhixiang Wei | 2020 | Chinese Journal of Chemistry2020，38，9： | 7 |
| 5 | Consumption Structure of Migrant Worker Families in China显示文摘这研究越过在中国城市化区域的四个学生在候鸟的调查上收 12 个城市并且调查城市的候鸟工人家庭和农村消费的结构。结果证明候鸟工人家庭消费的结构被幸存消费统治了。当在他们的农村自已出生的市镇从事明显的消费时,这些家庭趋于节约地住在城市。候鸟工人家庭消费的结构被他们的收入稳定性和财富层次而非他们的当前的收入水平主要塑造。而且,有打算在城市里永久地安定的高教育的层次和那些的候鸟工人家庭是可能的分配实质的开销到地位和快乐消费并且升级他们的城市的消费结构。 | Guangzhong Cao Kai Li Ruimin Wang Tao Liu | 2017 | China & World Economy2017，25，4： | 4 |
| 6 | Fluorination-substitution effect on all-small-molecule organic solar cells显示文摘Due to the strong crystallinity and anisotropy of small molecules, matched molecular photoelectric properties and morphologies between small molecules and non-fullerene acceptors are especially important in all-small-molecule organic solar cells(OSCs).Introducing fluorine atoms has been proved as an effective strategy to achieve a high device performance through tuning molecular energy levels, absorption and assembly properties. Herein, we designed a novel benzodithiophene-based small molecule donor BDTF-CA with deep highest occupied molecular orbital(HOMO) energy level. All-small-molecule OSCs were fabricated by combing non-fullerene acceptor IDIC with different fluorine-atom numbers. Two or four fluorine atoms were introduced to the end-capped acceptor of IDIC, which are named as IDIC-2 F and IDIC-4 F, respectively. With the increase of fluorination from IDIC to IDIC-4 F, the open circuit voltage(Voc) of the devices decreased, while hole and electron mobilities of the active layers increased by one order of magnitude. Contributed to the most balanced Voc, short-circuit current(Jsc) and fill factor(FF), the device based on BDTF-CA/IDIC-2 F achieved the highest power conversion efficiency of 9.11%. | Qiong Wu Dan Deng Jianqi Zhang Wenjun Zou Yang Yang Zhen Wang Huan Li Ruimin Zhou Kun Lu Zhixiang Wei | 2019 | Science China Chemistry2019，62，7： | 3 |
| 7 | Facile synthesis of porous nitrogen-doped holey graphene as an efficient metal-free catalyst for the oxygen reduction reaction显示文摘做氮的 graphene 是为氧减小反应(ORR ) 的高贵基于金属的 electrocatalysts 的代替的一个有希望的候选人。进做氮的 graphene 的毛孔和洞的增加由介绍丰富的暴露的边提高 ORR 活动,加速集体转移,并且阻碍 graphene 表的聚集。此处,我们在场为经由脲和镁醋酸盐 tetrahydrate 的热分解产生多孔的有穴的做氮的 graphene (PHNG ) 的直接却有效的策略。由于联合效果在里面 situ 产生了气体和 MgO nanoparticles,综合 PHNG 在弄皱的 graphene 之中展示了不仅众多的 out-of-plane 毛孔在装配 graphene 的表,而且贯穿的 nanoscale (5-15 nm ) 洞。而且,做 PHNG 的配置的氮被 thermal 以后处理在不同温度优化。pyridinic 和第四级的氮的全面内容断然与 ORR 活动相关,这被发现;特别地, pyridinic 氮为 ORR 产生最理想的特征。这个工作为基于 PHNG 的材料的合成揭示新线路并且阐明到 ORR 的各种各样的氮种类的贡献。 | Li Qin Ruimin Ding Huixiang Wang Jianghong Wu Conghui Wang Chenghua Zhang Yao Xu Liancheng Wang Baoliang Lv | 2017 | Nano Research2017，10，1： | 3 |
| 8 | Assessment of effects of best management practices on agricultural non-point source pollution in Xiangxi River watershed显示文摘 | Ruimin Liu Peipei Zhang Xiujuan Wang Yaxin Chen Zhenyao Shen | 2013 | Agricultural Water Management2013，，： | 3 |
| 9 | Inhibition of the toxic byproduct during photocatalytic NO oxidation via La doping in ZnO显示文摘It is of a great challenge to develop semiconductor photocatalysts with potential possibilities to simultaneously enhance photocatalytic efficiency and inhibit generation of toxic intermediates.In this study,we developed a facile method to induce the La doping and cationic vacancie(V(Zn))on ZnO for the highly efficient complete NO oxidation.The photocatalytic NO removal efficiency increases from 36.2%to 53,6%.Most importantly,a significant suppressed NO2 production also has been realized.According to the DFT calculations,ESR spectra and in situ FTIR spectra,the introduction of La^3+induce the redistribution of charge carriers in La-ZnO,which promote the production of·O2^- and lead to the formation of V(Zn)for the formation of·OH,contributing to the complete oxidation of NO to nitrate.Besides,the conversion pathway of photocatalytic NO oxidation has been elaborated,This work paves a new way to simultaneously realize the photocatalytic pollutants removal and the inhibition of toxic intermediates generation for efficient and safe air purification. | Chaowei Yuan Wen Cui Yanjuan Sun Jiadong Wang Ruimin Chen Jin Zhang Yuxin Zhang Fan Dong | 2020 | Chinese Chemical Letters2020，31，3： | 3 |
| 10 | Survivin Antisense Oligodeoxy-Nucleotid Induces Apoptosis in Leukaemia Cell Line K562显示文摘OBJECTIVE To investigate the effects of survivin antisense oligodeoxy-nucleotid (ASODN) on proliferation and apoptosis in the chronic myeloid leukemia cell line K562. METHODS Different concentrations of an antisense oligodeoxy-nucleotid and control sequence (scrambled ODN) targeting the survivin gene were transferred into K562 by a lipofectin reagent. The MTT assay was used to measure the growth inhibitory rate, IC50, and to observe the cytotoxicity of survivin ASODN in the K562 cells. The morphologic changes in the nucleus and the apoptotic rate were observed by Hoechst33342/PI staining. Caspase-3 activity was evaluated by a kinase activity assay. The changes of survivin protein expression after transfection were detected by Western blots. RESULTS Eight hours after transfection, fluorescence in the K562 cells was well distributed. Treatment of the cells for 44 h with different concentrations of survivin ASODN produced a IC50 of 800 nmol/L. The growth inhibitory rate with 200, 400, 600 and 1000 nmol/L of survivin ASODN was 15.8±1.6%, 23.8±5.9%, 37.1±5.6% and 77.3±2.5% respectively. After 36 h of of survivin ASODN treatment, distinct morphologic changes characteristic of cell apoptosis such as karyopyknosis and conglomeration were observed by Hoechst33342/PI staining. Caspase-3 activity increased significantly after treatment of the cells with different concentrations of survivin ASODN(P<0.01)and following treatment with 800 nmol/L survivin ASODN, survivin expression decreased significantly. CONCLUSION Survivin ASODN exerts an anti-cancer effect by inducing apoptosis in K562 leukaemia cells. Up-regulated expression of caspase-3 may play a role in this process. | Lijun Chen Qiuyue Jin Hong Xie Ruimin Wang Li Yao | 2006 | Chinese Journal of Clinical Oncology2006，3，6： | 3 |
| 11 | A-π-D-π-A small-molecule donors with different end alkyl chains obtain different morphologies in organic solar cells显示文摘For bulk-heterojunction organic solar cells, the morphology of the blend films highly influence the exciton dissociation and charge transport process. In this work, two novel A-π-D-π-A(A represents the acceptor unit and D represents the donor unit) backbone structure small molecular electron donors based on two dimensional conjugated naphtho[1,2-b:5,6-b']dithiophene(NDT) with different end alkyl chains, named as NDT-3T-EH and NDT-3T-O, have been designed and synthesized. The photovoltaic property of NDT-3T-O-based device is better than that of the NDT-3T-EH and the best efficiency reaches 7.06%, and the photovoltaic property of NDT-3T-EH reaches 6.11%. The difference in the performance should be attributed to the different morphology and phase separation resulted from the different crystallinity and aggregation ability of two donors. The results demonstrate that the optimized end alkyl chains can be used to design A-π-D-π-A backbone structure small molecular electron donors for smallmolecule organic solar cells. | Yanan Shi Chen Yang Huan Li Lixuan Liu Ruimin Zhou Wenjun Zou Zhen Wang Qiong Wu Dan Deng Jianqi Zhang Kun Lu Zhixiang Wei | 2019 | Chinese Chemical Letters2019，30，4： | 3 |
| 12 | Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation显示文摘The constitutive androstane receptor(CAR, NR3 I1) belongs to nuclear receptor superfamily.It was reported that CAR agonist TCPOBOP induces hepatomegaly but the underlying mechanism remains largely unknown. Yes-associated protein(YAP) is a potent regulator of organ size. The aim of this study is to explore the role of YAP in CAR activation-induced hepatomegaly and liver regeneration.TCPOBOP-induced CAR activation on hepatomegaly and liver regeneration was evaluated in wildtype(WT) mice, liver-specific YAP-deficient mice, and partial hepatectomy(PHx) mice. The results demonstrate that TCPOBOP can increase the liver-to-body weight ratio in wild-type mice and PHx mice.Hepatocytes enlargement around central vein(CV) area was observed, meanwhile hepatocytesproliferation was promoted as evidenced by the increased number of KI67+cells around portal vein(PV)area. The protein levels of YAP and its downstream targets were upregulated in TCPOBOP-treated mice and YAP translocation can be induced by CAR activation. Co-immunoprecipitation results suggested a potential proteineprotein interaction of CAR and YAP. However, CAR activation-induced hepatomegaly can still be observed in liver-specific YAP-deficient(Yape/e) mice. In summary, CAR activation promotes hepatomegaly and liver regeneration partially by inducing YAP translocation and interaction with YAP signaling pathway, which provides new insights to further understand the physiological functions of CAR. | Yue Gao Shicheng Fan Hua Li Yiming Jiang Xinpeng Yao Shuguang Zhu Xiao Yang Ruimin Wang Jianing Tian Frank JGonzalez Min Huang Huichang Bi | 2021 | Acta Pharmaceutica Sinica B2021，11，3： | 2 |
| 13 | An Economic Benefit Evaluation Model and its Application for Optimizing Transmission Capacity of Multinational Interconnections显示文摘Multinational power grid interconnections play a critical part in supporting the vision of global energy internet.During the early stages of the Global Energy Internet,the value proposition of multinational interconnections should be carefully investigated in order to stimulate the activities for associated countries in such potential interconnections.This paper proposes a new e conomic benefit evaluation model which is quantified by using a chronological production cost simulation approach.The economic benefit model comprehensively considered investment costs and the benefits of the decrease of load payments and the increase of net generation revenue due to a transmission project interconnected with different countries.This economic benefit model can assist to quantitatively determine the optimal transmission capacity for multinational interconnections to achieve maximum economic benefits as a whole.In the case study,the economic benefit of an interconnected system of western China and the Gulf States is assessed by using the method proposed in this paper.And the optimal interconnection capacity with maximum benefit is achieved.The case study shows that the proposed method can be used for economic benefit assessment and is of great significance to the multinational and intercontinental transmission interconnections. | Xiaojun Wang Ruimin Jiang Pei Zhang Yunfei Mu Maosheng Ding | 2018 | CSEE Journal of Power and Energy Systems2018，4，4： | 2 |
| 14 | Nonlinear Prediction with Deep Recurrent Neural Networks for Non-Blind Audio Bandwidth Extension显示文摘Non-blind audio bandwidth extension is a standard technique within contemporary audio codecs to efficiently code audio signals at low bitrates. In existing methods, in most cases high frequencies signal is usually generated by a duplication of the corresponding low frequencies and some parameters of high frequencies. However, the perception quality of coding will significantly degrade if the correlation between high frequencies and low frequencies becomes weak. In this paper, we quantitatively analyse the correlation via computing mutual information value. The analysis results show the correlation also exists in low frequency signal of the context dependent frames besides the current frame. In order to improve the perception quality of coding, we propose a novel method of high frequency coarse spectrum generation to improve the conventional replication method. In the proposed method, the coarse high frequency spectrums are generated by a nonlinear mapping model using deep recurrent neural network. The experiments confirm that the proposed method shows better performance than the reference methods. | Lin Jiang Ruimin Hu Xiaochen Wang Weiping Tu Maosheng Zhang | 2018 | China Communications2018，15，1： | 2 |
| 15 | Research Review on Marine Search and Rescue显示文摘 | CHEN Xinqiang SHI Chaojian WANG Shengzheng WU Huafeng XU Tie KE Ruimin | 2017 | Journal of Shipping and Ocean Engineering2017，7，3： | 2 |
| 16 | A Great late Ediacaran ice age显示文摘The emergence of the Ediacara biota soon after the Gaskiers glaciation ca.580 million years ago(Ma)implies a possible glacial fuse for the evolution of animals.However,the timing of Ediacaran glaciation remains controversial because of poor age constraints on the∼30 Ediacaran glacial deposits known worldwide.In addition,paleomagnetic constraints and a lack of convincing Snowball-like cap carbonates indicate that Ediacaran glaciations likely did not occur at low latitudes.Thus,reconciling the global occurrences without global glaciation remains a paradox.Here,we report that the large amplitude,globally synchronous ca.571–562 Ma Shuram carbon isotope excursion occurs below the Ediacaran Hankalchough glacial deposit in Tarim,confirming a post-Shuram glaciation.Leveraging paleomagnetic evidence for a∼90°reorientation of all continents due to true polar wander,and a non-Snowball condition that rules out low-latitude glaciations,we use paleogeographic reconstructions to further constrain glacial ages.Our results depict a‘Great Ediacaran Glaciation’occurring diachronously but continuously from ca.580–560 Ma as different continents migrated through polar–temperate latitudes.The succession of radiation,turnover and extinction of the Ediacara biota strongly reflects glacial–deglacial dynamics. | Ruimin Wang Bing Shen Xianguo Lang Bin Wen Ross N.Mitchell Haoran Ma Zongjun Yin Yongbo Peng Yonggang Liu Chuanming Zhou | 2023 | National Science Review2023，10，8： | 2 |
| 17 | Arbitrary Scale Super Resolution Network for Satellite Imagery显示文摘Recently,satellite imagery has been widely applied in many areas.However,due to the limitations of hardware equipment and transmission bandwidth,the images received on the ground have low resolution and weak texture.In addition,since ground terminals have various resolutions and real-time playing requirements,it is essential to achieve arbitrary scale super-resolution(SR)of satellite images.In this paper,we propose an arbitrary scale SR network for satellite image reconstruction.First,we propose an arbitrary upscale module for satellite imagery that can map low-resolution satellite image features to arbitrary scale enlarged SR outputs.Second,we design an edge reinforcement module to enhance the highfrequency details in satellite images through a twobranch network.Finally,extensive upsample experiments on WHU-RS19 and NWPU-RESISC45 datasets and subsequent image segmentation experiments both show the superiority of our method over the counterparts. | Jing Fang Jing Xiao Xu Wang Dan Chen Ruimin Hu | 2022 | China Communications2022，19，8： | 2 |
| 18 | On-line RNN compensated second order nonsingular terminal sliding mode control for hypersonic vehicle显示文摘Purpose–The purpose of this paper is to design a robust control scheme to achieve robust tracking of velocity and altitude commands for a general hypersonic vehicle(HSV)in the presence of parameter variations and external disturbances.Design/methodology/approach–The robust control scheme is composed of nonsingular terminal sliding mode control(NTSMC),super twisting control algorithm(STC)and recurrent neural network(RNN).First,by combing a novel NTSMC and STC algorithm,a second order NTSMC approach for HSV is proposed to provide fast,continuous and high precision tracking control.Second to relax the requirements for the bounds of the lumped uncertainties in control design,a RNN disturbance observer is presented to increase the robustness of the control system.The weights of RNN are updated by adaptive laws based on Lyapunov theorem,thus the closed-loop stability can be guaranteed.Findings–Simulation results demonstrate that the proposed method is effective,leading to promising performance.Originality/value–The main contributions of this work are:first,both parameter variations and external disturbances are considered in control design for the longitudinal dynamic model of HSV;and second,the proposed controller can remove chattering and achieve more favorable tracking performances than conventional sliding mode control. | Ruimin Zhang Li Wang Yingjiang Zhou | 2012 | International Journal of Intelligent Computing and Cybernetics2012，5，2： | 1 |
| 19 | A millime- ter-wave gain equalizer using E-plane microstrip line probe and waveguide resonator 显示文摘 | Zhigang Wang Bo Yan Ruimin Xu | 2015 | Journal of Electromagnetic Waves and Applications2015，29，4： | 1 |
| 20 | Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3β signaling显示文摘 | Caifeng Zhou Jingyi Tu Quanguang Zhang Dongshuang Lu Ying Zhu Wenli Zhang Fang Yang Darrell W. Brann Ruimin Wang | 2011 | Neurochemistry International2011，，6： | 1 |
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