|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 肠道菌群在功能性便秘中的作用显示文摘功能性便秘非常常见,但其发病机制尚不明了。越来越多的证据显示,功能性便秘与肠道微生态失调有关,而肠道微生态与肠道转运之间很可能存在相互影响。本文对功能性便秘发生过程中肠道微生态所发挥作用的证据进行了总结。肠道微生态通过胆酸、短链脂肪酸、5-羟色胺和甲烷等相关微生物代谢活动调控结肠动力、结肠黏膜分泌和吸收,进而促使功能性便秘的发生。作为肠道微生态影响功能性便秘的证据支持,用益生菌、益生元、合生元和中药治疗功能性便秘时,常可观察到患者肠道微生态在菌种组成和功能上的改变。深入研究功能性便秘的病理发生,阐明微生态制剂治疗功能性便秘的药理机制,将为功能性便秘的新型治疗方法提供理论基础。 | Shengsheng Zhang Ruixin Wang Danyan Li Luqing Zhao Lixin Zhu | 2021 | Gastroenterology Report2021，9，5： | 13 |
| 2 | Development of a supercritical and an ultra-supercritical circulating fluidized bed boiler显示文摘The supercritical circulating fluidized bed(CFB)boiler,which combines the advantages of CFB combustion with low cost emission control and supercritical steam cycle with high efficiency of coal energy,is believed to be the future of CFB combustion technology.It is also of greatest importance for low rank coal utilization in China.Different from the supercritical pulverized coal boiler that has been developed more than 50 years,the supercritical CFB boiler is still a new one which requires further investigation.Without any precedentor engineering reference,Chinese researchers have con ducted fundamental research,development,design of the supercritical CFB boilers independently.The design theory and key technology for supercritical CFB boiler were proposed.Key components and novel structures were invented.The first 600 MWe supercritical CFB boiler and its auxiliaries were successfully developed and demonstrated in Baima Power Plant,Shenhua Group as well as the simulator,control technology,installation technology,commissioning technology,system integration and operation technology.Compared with the 460 MWe supercritical CFB in Poland,developed in the same period and the only other supercritical one of commercial running in the word beside Baima,the 600 MWe one in Baima has a better performance.Besides,supercritical CFB boilers of 350 MWe have been developed and widely commercialized in China.In this paper,the updated progress of 660 MWe ultra-supercritical CFB boilers under development is introduced. | Junfu LYU Hairui YANG Wen LING Li NIE Guangxi YUE Ruixin LI Ying CHEN Shilong WANG | 2019 | Frontiers in Energy2019，13，1： | 11 |
| 3 | Effects of total soy saponins on free radicals in the quadriceps femoris,serum testosterone,LDH,and BUN of exhausted rats显示文摘Purpose:The aim of this study was to investigate the impact of total soy saponins(TS) on the free radical metabolism from the quadriceps femoris muscle,serum testosterone,lactate dehydrogenase(LDH),and blood urea nitrogen(BUN) in rats exercised to exhaustion.Methods:A one-time exhausted treadmill exercise session was used.Sprague-Dawley rats were divided into 4 groups:a control group—animals receiving no TS and no exercise(NTSNE),animals receiving TS but no exercise group(TSNE),animals receiving no TS but exercised to exhaustion group(NTSE),and animals receiving TS and exercised to exhaustion group(TSE).The TSNE and TSE groups were fed TS at a dosage of 20 mg/kg body weight once per day for 2 weeks.The NTSE group was given a placebo,and the NTSNE group was not given any treatment.The NTSE and TSE groups were exercised at speed of 30 m/min on treadmill until exhausted.The exercise time and exercise distance were recorded when the rats became exhausted and the rats were then decapitated and anatomized immediately.A 10% homogenate of the quadriceps femoris tissue was prepared.The levels of superoxide dismutase(SOD),catalase(CAT),malondialdehyde(MDA),glutathione peroxidase(GSH-Px),glutathione reductase(GR),reduced glutathione(GSH),total antioxidant capacity(T-AOC),LDH,BUN,and serum testosterone were tested.Results:TS significantly increased the exercise time to exhaustion by 20.62%(p < 0.05).The MDA levels were decreased significantly in the TSNE group than in NTSNE group(p < 0.05);the T-AOC levels increased significantly in the TSNE group than in the other 3 groups(p < 0.01,p < 0.05,p < 0.05).The LDH activity significantly increased in the NTSE group than in TSNE group(p < 0.05).The BUN levels significantly increased in the NTSE group than in the other 3 groups(p < 0.01,p < 0.01,p < 0.05),and significantly increased in the TSE group than in NTSNE and TSNE groups(both p < 0.01).The serum testosterone levels increased significantly in the TSNE group than in the other 3 groups(all p < 0.01).SOD,CAT,GSH-Px,GR,and GSH were not statistically different among the groups.Conclusion:TS can significantly improve the exercised rats' serum testosterone level and antioxidant activity in their quadriceps femoris to varying degrees,decrease MDA and serum LDH and BUN levels,increase the exercise time,and delay the occurrence of the fatigue. | Zhigang Liu Ruixin Nie Yun Liu Zhouhong Li Chenxi Yang Zhengying Xiong | 2017 | Journal of Sport and Health Science2017，6，3： | 8 |
| 4 | Three-dimensional dynamic culture of pre-osteoblasts seeded in HA-CS/Col/nHAP composite scaffolds and treated with α-ZAL显示文摘造骨细胞前 MC3T3-E1 房间在玻尿的修改酸的 chitosan/collagen/nano-hydroxyapatite (HA-CS/Col/nHAP ) 是有教养的合成脚手架并且与 phytoestrogen 对待 -zearalanol (为骨头织物工程改进骨头织物形成的 -ZAL) 。灌注和动态紧张被用于三维(3D ) 有教养的房间,它在骨头组织模仿机械微型环境并且解决集体转移问题。在 vitro 的房间支架构造的形态学然后被检验,成骨的标记被 immunohistochemistry 染色并且西方的弄污估计。结果证明房间以一种不规则的方式扩展了他们的 pseudopodia 并且在 3D-dynamic 文化沿着墙分散了。Osteogenic 显型被增加或由提高的骨胶原坚持说(COLI ) 我铺平,减少的 osteopontin 表示和有的很少在 12 天期间在 osteocalcin 上完成表示在 vitro 文化。响应 -ZAL, ,房间支架构造显示出禁止的细胞的增长,提高了碱的磷酸酶(高山) 活动和到原子因素 kappa B (NF-B ) ligand (RANKL ) 的受体使活跃之物的 osteoprotegerin 的增加的比率。到与 -ZAL 对待的房间支架构造的灌注和动态紧张的申请在骨头织物工程的成骨刺激的研究代表一条有希望的途径。 | Lu Liu Yong Guo Xuezhong Chen Ruixin Li Zhihong Li Liang Wang Zongming Wan Jianyu Li Qingxin Hao Hao Li Xizheng Zhang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，8： | 7 |
| 5 | Broadband photonic radio frequency(RF) channelization based on coherent optical frequency combs and polarization I/Q demodulation显示文摘In this work,we analyze and demonstrate a novel photonic-assisted broadband and high-resolution radio frequency(RF) channelization scheme based on dual coherent optical frequency combs(OFCs),regular optical de-muxes,and polarization I/Q demodulators in theory and experiment.The use of two coherent combs avoids precise optical alignment,and a numerical filter in digital signal processor(DSP) enables an ideal rectangular frequency response in each channel without any ultra-narrow optical filters.Besides,due to the use of polarization I/Q demodulation,ambiguous frequency estimate in direct detection can be avoided and the amplitude,phase mismatch in traditional I/Q demodulation can be mitigated.In experiment,we use two coherent OFCs with the free spectrum range(FSR) of about 40 GHz to demonstrate the channelization scheme with seven channels,500 MHz channel spacing and frequency coverage from 3.75 GHz to 7.25 GHz.The input RF tones are accurately down-converted to an intermediate frequency(IF) with a maximum frequency error of 110 kHz.Meanwhile,crosstalk and spurious free dynamic range(SFDR) of the scheme are also discussed. | DAI YiTang XU Kun XIE XiaoJun YAN Li WANG RuiXin LIN JinTong | 2013 | Chinese Science Bulletin2013，58，7： | 5 |
| 6 | Microwave photonics: radio-over-fiber links, systems, and applications [Invited]显示文摘Microwave photonics(MWPs)uses the strength of photonic techniques to generate,process,control,and distribute microwave signals,combining the advantages of microwaves and photonics.As one of the main topics of MWP,radio-over-fiber(RoF)links can provide features that are very difficult or even impossible to achieve with traditional technologies.Meanwhile,a considerable number of signal-processing subsystems have been carried out in the field of MWP as they are instrumental for the implementation of many functionalities.However,there are still several challenges in strengthening the performance of the technology to support systems and applications with more complex structures,multiple functionality,larger bandwidth,and larger processing capability.In this paper,we identify some of the notable challenges in MWP and review our recent work.Applications and future direction of research are also discussed. | Kun Xu Ruixin Wang Yitang Dai Feifei Yin Jianqiang Li Yuefeng Ji Jintong Lin | 2014 | Photonics Research2014，2，4： | 4 |
| 7 | Cold spray additive manufacturing of Invar 36 alloy:microstructure,thermal expansion and mechanical properties显示文摘In this work,the Invar 36 alloys were manufactured using cold spray(CS)additive manufacturing technique.The systematic investigations were made on the microstructural evolution,thermal expansion and mechanical properties under as-sprayed(AS)and heat-treated(HT)conditions.XRD(X-ray diffraction)and ICP-AES(inductively coupled plasma atomic emission spectroscopy)analyses show that no phase transformation,oxidation,nor element content change have occurred.The X-ray computed tomography(XCT)exhibited a near fully dense structure with a porosity of 0.025%in the helium-produced sample under as-sprayed condition,whereas the nitrogen-produced samples produced at 5 MPa and 800℃show more irregular pore defects.He-AS sample shows a more prominent grain refinement than that of nitrogen samples due to the more extensive plastic deformation.The post heat-treatment exhibited a promoted grain growth,inter-particle diffusion,as well as the formation of annealing twins.Between25℃and 200℃,the nitrogen samples possessed lower CTE(coefficient of thermal expansion)values(1.53×10^(-6)/℃)compared with those produced by casting and laser additive manufacturing.The He-AS samples exhibited a noticeable negative CTE value between 25℃and 200℃,which may due to the significant compressive residual stress(-272 MPa)compensating its displacement with temperature increase during CTE test.The N2-HT and He-HT Invar 36 samples present a notable balance between strength and ductility.In conclusion,the CS technique can be considered as a potential method to produce the Invar36 component with high thermal and mechanical performance. | Chaoyue Chen Yingchun Xie Longtao Liu Ruixin Zhao Xiaoli Jin Shanqing Li Renzhong Huang Jiang Wang Hanlin Liao Zhongming Ren | 2021 | Journal of Materials Science & Technology2021，，13： | 4 |
| 8 | Modulating Sand’s time by ion-transport-enhancement toward dendrite-free lithium metal anode显示文摘Metallic lithium is deemed as the“Holy Grail”anode in high-energy-density secondary batteries.Uncontrollable lithium dendrite growth and related issues originated from uneven concentration distribution of Li+in the vicinity of the anode,however,induce severe safety concerns and poor cycling efficiency,dragging lithium metal anode out of practical application.Herein we address these issues by using cross-linked lithiophilic amino phosphonic acid resin as the effective host with the ion-transportenhancement feature.Based on theoretical calculations and multiphysics simulation,it is found that this ion-transportenhancement feature is capable of facilitating the self-concentration kinetics of Li+and accelerating Li^(+)transfer at the electrolyte/electrode interface,leading to uniform bulk lithium deposition.Experimental results show that the proposed lithiumhosting resin decreases the irreversible lithium capacity and improves lithium utilization(with the Coulombic efficiency(CE)of 98.8%over 130 cycles).Our work demonstrates that inducing the self-concentrating distribution of Li+at the interface can be an effective strategy for improving the interfacial ion concentration gradient and optimizing lithium deposition,which opens a new avenue for the practical development of next-generation lithium metal batteries. | Yu Yan Chaozhu Shu Ruixin Zheng Minglu Li Zhiqun Ran Miao He Anjun Hu Ting Zeng Haoyang Xu Ying Zeng | 2022 | Nano Research2022，15，4： | 2 |
| 9 | Preface显示文摘Owing to the fast economic growing and the concern over greenhouse gases and air pollution,the development of nuclear energy is one important option to meet the expanded energy consumption in our future.To achieve that goal,continuing and reliable supplies of uranium are critical to future nuclear power projects.As is well known,global terrestrial reserves of uranium are limited and the deposits in China are relatively small.Given the projected big growth in nuclear power in the future,reliable supply of uranium at a reasonable price is essential for China. | DAI YiTang XU Kun XIE XiaoJun YAN Li WANG RuiXin LIN JinTong | 2013 | Science China Chemistry2013，56，11： | 2 |
| 10 | Effects of different aperture-sized type I collagen/silk fibroin scaffolds on the proliferation and differentiation of human dental pulp cells显示文摘This study aimed at evaluate the effects of different aperture-sized type I collagen/silk fibroin(CSF)scaffolds on the proliferation and differentiation of human dental pulp cells(HDPCs).The CSF scaffolds were designed with 3D mapping software Solidworks.Three different aperture-sized scaffolds(CSF1-CSF3)were prepared by low-temperature deposition 3D printing technology.The morphology was observed by scanning electron microscope(SEM)and optical coherence tomography.The porosity,hydrophilicity and mechanical capacity of the scaffold were detected,respectively.HDPCs(third passage,1105 cells)were seeded into each scaffold and investigated by SEM,CCK-8,alkaline phosphatase(ALP)activity and HE staining.The CSF scaffolds had porous structures with macropores and micropores.The macropore size of CSF1 to CSF3 was 421627 lm,579636 lm and 707643 lm,respectively.The porosity was 69.862.2%,80.162.8%and 86.563.3%,respectively.All these scaffolds enhanced the adhesion and proliferation of HDPCs.The ALP activity in the CSF1 group was higher than that in the CSF3 groups(P<0.01).HE staining showed HDPCs grew in multilayer within the scaffolds.CSF scaffolds significantly improved the adhesion and ALP activity of HDPCs.CSF scaffolds were promising candidates in dentine-pulp complex regeneration. | Shihui Jiang Zhaoxia Yu Lanrui Zhang Guanhua Wang Xiaohua Dai Xiaoli Lian Yan Yan Linpu Zhang Yue Wang Ruixin Li Huiru Zou | 2021 | Regenerative Biomaterials2021，8，4： | 2 |
| 11 | PARTICLE SWARM OPTIMIZATION ON FLEXIBLE DOCKING显示文摘 | YU LIU WENTAO LI RUIXIN MA | 2012 | International Journal of Biomathematics2012，5，5： | 2 |
| 12 | MicroRNA?133a inhibits proliferation and invasion, and induces apoptosisin gastric carcinoma cells via targeting fascin actin?bundling protein 1显示文摘 | Chen Lai Zihua Chen Ruixin Li | 2015 | Molecular Medicine Reports2015，，1： | 1 |
| 13 | Low temperature synthesis of nanosize rutile titania crystal in liquid media 显示文摘 | Shu Yin Ruixin Li Qinglin He | 2002 | Materials Chemistry and Physics2002，75，1： | 1 |
| 14 | Novel non-noble metal electrocatalysts synthesized by heat-treatment of iron terpyridine complexes for the oxygen reduction reaction显示文摘 | Jiatang Wang Shang Li Guangwen Zhu Wei Zhao Ruixin Chen Mu Pan | 2013 | Journal of Power Sources2013，，： | 1 |
| 15 | Design,Fabrication and Experiments of an Anthropomorphic Finger with Combined Compliant Joints显示文摘Fingers are the basic components of anthropomorphic hands.At present,most anthropomorphic fingers utilize rigid joints,which have obvious fabrication and assembly complexities as well as limited flexibility and adaptability.Thus,some anthropomorphic fingers were attempted to utilize compliant joints learned from bioinspiration,but they have a limited self-resetting ability and lateral deformation resistance,as well as occupying a large space and having a non-anthropomorphic appearance.In this paper,nine compliant joints for anthropomorphic fingers were analyzed using Finite Element Analysis(FEA),based on which two combined compliant joints were proposed,and the optimal one was obtained through FEA and experiments.An anthropomorphic finger that embeds parts of the compliant joint into the adjacent phalanxes was then designed.Finally,the anthropomorphic finger was fabricated and experiments were conducted.Experimental results show that the anthropomorphic finger with the proposed combined compliant joints has a better self-resetting ability and lateral deformation resistance while ensuring a large range of motion similar to that of the human finger,and the required actuating force is reasonable.Furthermore,the embedded joint structure can reduce the occupied space of the joint so as to improve the anthropomorphic appearance of the finger,and enhance its lateral deformation resistance. | Yin Zhang Qiang Zhan Ruixin Li Xinyu Bao | 2020 | Journal of Bionic Engineering2020，17，6： | 1 |
| 16 | On the applications of SVD in fault diagnosis显示文摘 | Li Ruixin Wang Dongfeng Han Pu | 2003 | IEEE International Conference on Systems Man and Cybernetics2003，4，5： | 1 |
| 17 | A Study of FSS in Terahertz Range for Polarization Modula-tion Purpose显示文摘 | Kejian Chen Zhou Li Jingjing Liu Ruixin Duan Yiqi Wang Wen Zhang Bin Cai Lin Chen Yiming Zhu | | 0，，： | 1 |
| 18 | A quick and reliable image-based AI algorithm for evaluating cellular senescence of gastric organoids显示文摘Objective:Organoids are a powerful tool with broad application prospects in biomedicine.Notably,they provide alternatives to animal models for testing potential drugs before clinical trials.However,the number of passages for which organoids maintain cellular vitality ex vivo remains unclear.Methods:Herein,we constructed 55 gastric organoids from 35 individuals,serially passaged the organoids,and captured microscopic images for phenotypic evaluation.Senescence-associatedβ-galactosidase(SA-β-Gal),cell diameter in suspension,and gene expression reflecting cell cycle regulation were examined.The YOLOv3 object detection algorithm integrated with a convolutional block attention module(CBAM)was used to evaluate organoid vitality.Results:SA-β-Gal staining intensity;single-cell diameter;and expression of p15,p16,p21,CCNA2,CCNE2,and LMNB1 reflected the progression of aging in organoids during passaging.The CBAM-YOLOv3 algorithm precisely evaluated aging organoids on the basis of organoid average diameter,organoid number,and number×diameter,and the findings positively correlated with SA-β-Gal staining and single-cell diameter.Organoids derived from normal gastric mucosa had limited passaging ability(passages 1–5),before aging,whereas tumor organoids showed unlimited passaging potential for more than 45 passages(511 days)without showing clear senescence.Conclusions:Given the lack of indicators for evaluating organoid growth status,we established a reliable approach for integrated analysis of phenotypic parameters that uses an artificial intelligence algorithm to indicate organoid vitality.This method enables precise evaluation of organoid status in biomedical studies and monitoring of living biobanks. | Ruixin Yang Yutong Du Wingyan Kwan Ranlin Yan Qimeng Shi Lu Zang Zhenggang Zhu Jianming Zhang Chen Li Yingyan Yu | 2023 | Cancer Biology & Medicine2023，20，7： | 1 |
| 19 | Performance-improving techniques in web-based GIS显示文摘 | Chaowei Yang David W. Wong Ruixin Yang Menas Kafatos Qi Li | 2005 | International Journal of Geographical Information Science2005，，3： | 1 |
| 20 | Performance-improving techniques in web-based GIS显示文摘 | Chaowei Yang David W. Wong Ruixin Yang Menas Kafatos Qi Li | 2005 | International Journal of Geographical Information Science2005，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员