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| 1 | Wavelet denoising via sparse representation显示文摘Wavelet threshold denoising is a powerful method for suppressing noise in signals and images. However, this method often uses a coordinate-wise processing scheme, which ignores the structural properties in the wavelet coefficients. We propose a new wavelet denoising method using sparse representation which is a powerful mathematical tool recently developed. Instead of thresholding wavelet coefficients individually, we minimize the number of non-zero coefficients under certain conditions. The denoised signal is reconstructed by solving an optimization problem. It is shown that the solution to the optimization problem can be obtained uniquely and the estimates of the denoised wavelet coefficients are unbiased, i.e., the statistical means of the estimates are equal to the noise-free wavelet coefficients. It is also shown that at least a local optimal solution to the denoising problem can be found. Our experiments on test data indicate that this new denoising method is effective and efficient for a wide variety of signals including those with low signal-to-noise ratios. | ZHAO RuiZhen LIU XiaoYu Ching-Chung LI Robert J. SCLABASSI & SUN MinGui | 2009 | Science in China(Series F)2009，52，8： | 26 |
| 2 | Fine mapping of locus S-b for F_1 pollen sterility in rice (Oryza sativa L.)显示文摘Hybrid sterility is the main barrier in util-izing the heterosis of subspecies in rice. A knowledge of the underlying molecular mechanism of the hybrid sterility will be useful for overcoming the barrier. In this research, the F1 pollen sterility locus, S-b, was mapped between SSR markers PSM8 and PSM202. To fine map the locus, one F2 mapping population of 3910 plants was developed using the near-isogenic lines of the locus. Ninety-seven recombinants be-tween two markers were selected. Moreover, a series of markers, including two SSR markers, two InDel markers and four CAPS markers, were developed on the region. Linkage analysis showed that marker W4 was co-segregated with locus S-b, while makers A8 and A14 were located on the two sides of the locus with a distance of 0.026 and 0.038 cM, respectively. The markers were then integrated with the se-quences of the clones of the region. Results showed that all the polymorphic markers were anchored on the three end-to-end jointed clones AC093089, AC079021 and AC134931. According to the physical information of the markers, locus S-b was finally de-limited to a region of 27 kb between A8 and A14. Seven ORFs were identified on the region based on the annotation results of RiceGAAS system. These results laid the foundation for further cloning the gene. | LI Wentao ZENG Ruizhen ZHANG Zemin DING Xiaohua ZHANG Guiquan | 2006 | Chinese Science Bulletin2006，51，6： | 12 |
| 3 | Nuclear reprogramming: the zygotic transcription program is established through an“erase-and-rebuild” strategy显示文摘卵母细胞显示母亲特定的基因表达式侧面,它被换到当染色质的一个单倍体集合被传递到发展成一个胚胎的受精卵时, zygotic 介绍。位于这抄写 reprogramming 下面的机制当前是未知的。等到当抄写在幼芽的泡卵母细胞被关掉时,一般抄写因素和 transcriptional 管理者的一个范围从染色质被分裂,这里,我们表明那。染色质因素(CF ) 的全球分离破坏在染色质和 CF 之间的物理接触并且在功能的水平导致母亲的抄写节目的檫除。与染色质论坛分开的批评抄写因素和管理者遗体延长了时期,并且立即在专业版以后与染色质成为 re-associated 原子形成。Thisis 由象 DNA 和抄写那样的原子功能的重建跟随了速度集合。我们建议母亲的抄写节目在卵子发生期间被擦掉产生相对天真的染色质, zygotic 抄写节目是在授精以后的重建的重新。这个过程作为“ erase-and-rebuild ”被称为过程,它被用来重设抄写节目,和最可能的其它原子过程也,从母亲的到胚胎的。我们进一步在伴随的纸出现(高 T,等,房间物件 2007;17:135-150 .) 一样的策略也被采用到改编 transcriptional,这在体细胞介绍原子转移和单性生殖,建议这当模特儿在早胚胎开始期间对 transcriptional reprogramming 的所有形式普遍适用。从染色质的 CF 的排水量也为抄写沉默的现象提供解释在期间对 zygotic 转变母亲。 | Feng Sun Haiyan Fang Ruizhen Li Tianlong Gao Junke Zheng Xuejin Chen Wenqin Ying Hui Z Sheng | 2007 | Cell Research2007，17，2： | 5 |
| 4 | Combination of Human Fas (CD95/Apo-1) Ligand with Adriamycin Significantly Enhances the Efficacy of Antitumor Response显示文摘hepatocellular 癌(HCC ) 的预后是差的,甚至与药品切除术和辅助 chemoradiotherapy 的联合治疗。解决这个问题,许多生物学的治疗被调查了。船边交货 ligand (FasL, CD95L ) 主要在激活的 T 淋巴细胞和生来的杀手(NK ) 房间被表示,并且在调停房间的免疫和有免疫力的 downregulation 起一个中央作用。几研究证明了 FasL 在 HCC 被表示。在现在的报告,我们准备了 recombinant 人 pET-22b (+)/FasL 蛋白质并且在一个鼠科的 HCC 肿瘤模型在 vitro 并且在肿瘤生长上在 HCC 房间上调查了 FasL 的效果。著名细胞毒素的化学疗法的试剂 adriamycin (ADM ) 用作控制。我们发现 FasL 有效地压制了 H22 肿瘤房间的生存能力并且显著地导致了 H22 房间的 apoptosis。与 FasL-ADM 对待的细胞的 apoptotic 层次比独自与 FasL 或 ADM 对待的那些显著地高,并且 FasL-ADM 联合导致了一非常在这个模型的肿瘤生长延期上的添加剂效果。结果建议 FasL 和另外的化学疗法的代理人的那个联合处理可以是一条新途径为 HCC 改进化疗的功效。 | Zhongchen Liu Ruizhen Liu Jinhua Qiu Ping Yin Fanghong Luo Jinhua Su Wenzhu Li Caixia Chen Xin Fan Jiakai Zhang Guohong Zhuang | 2009 | Cellular & Molecular Immunology2009，6，3： | 4 |
| 5 | An Asynchronous Adaptive Priority Round-Robin Arbiter Based on Four-Phase Dual-rail Protocol显示文摘An asynchronous Adaptive priority roundrobin arbiter(APRA) based on four-phase dual-rail protocol is proposed. Combining the advantages of synchronous and asynchronous circuits, it provides the required bandwidth allocation on basis of arbitration fairness and works in synchronous So C. In the Nonidling and nonpreemptive(NINP) model, simulations and verifications are made. The results show that the speed of the proposed arbiter is improved by 18%–50.4% and the dynamic and static power is reduced by 8.4%–46.2% and 81.8%–90.9% respectively compared with the commonly-used Fixed priority(FP),Round-Robin(RR) and Lottery arbiters. The proposed arbiter is better in output bandwidth allocation and it also has advantages in speed and power. Furthermore, it is easy in reconfiguration, strong in practicability and low in complexity of system integration and suits various extreme communication traffics. | YANG Yintang WU Ruizhen ZHANG Li ZHOU Duan | 2015 | Chinese Journal of Electronics2015，24，1： | 3 |
| 6 | Effect of REs(Y,Nd)addition on high temperature oxidation kinetics,oxide layer characteristic and activation energy of AZ80 alloy显示文摘The oxidation behaviors of AZ80,AZ8O-0.32 Y and AZ8O-0.38 Nd(wt.%)alloys were researched at 413℃,420℃,427v and 433℃for up to 6 h in air environment via a high precision analytical balance,a laser confocal microscope,differential scanning calorimeter(DSC)analysis,X-ray diffraction(XRD)analysis,scanning electron microscope(SEM)observation,and X-ray photoelectron spectroscopy(XPS)analysis.The results show that the weight gain and oxidation rate of AZ80 are reduced significantly,the initiation form and propagation of cracks in oxide layer are changed.Compact and protective oxide layer forms on alloy surface with Y or Nd addition.And the activation energies of AZ80,AZ80-0.32Y and AZ8O-0.38Nd alloys calculated via Arrhenius equation are 82.556 kJ/mol,177.148kJ/mol and 136.738 kJ/mol,respectively. | Chunlong Cheng Xiaoqiang Li Qichi Le Ruizhen Guo Qing Lan Jianzhong Cui | 2020 | Journal of Magnesium and Alloys2020，8，4： | 3 |
| 7 | A composite of Ni-Fe-Zn layered double hydroxides/biochar for atrazine removal from aqueous solution显示文摘This study assembled corn stalk-derived biochar(BC)with layered double hydroxide(LDH)through a rapid coprecipitation of biochar and metal(Ni/Fe/Zn)hydroxide precipitates.A BC and LDH composite(BC-LDH)and modified BC-LDH material after heating(BC-LDH-P)were prepared successfully for atrazine adsorptive removal.The physicochemical properties of the synthesized samples were analyzed by X-ray diffraction(XRD),scanning electron microscopy(SEM),Fourier transform infrared(FT-IR),and X-ray photoelectron spectroscopy(XPS).Batch experiments were conducted to study the sorption of atrazine onto BC,BC-LDH,and BC-LDH-P from the aqueous solution.The adsorption of atrazine onto BC-LDH and BC-LDH-P were performed following with the pseudo-second-order kinetic model,and the sorption isotherms agreed well with the Freundlich fitting model.The adsorption amounts of the three materials are arranged in descending order is as follows:BC-LDH-P>BC-LDH>BC(143.15>123.10>95.93 mg g−1,respectively).Due to the high crystallinity of the LDH material and the high binding degree with biochar,Ni/Fe/Zn-LDH biochar composites offer a potential alternative to a carbon-based adsorbent for atrazine removal from aqueous solution. | Yifan Wang Jiaming Kang Simeng Jiang Hui Li Zheyi Ren Qinbo Xu Qun Jiang Wenzhu Liu Ruizhen Li Ying Zhang | 2020 | Biochar2020，2，4： | 2 |
| 8 | RGD-FasL Induces Apoptosis in Hepatocellular Carcinoma显示文摘尽管有在动物模型获得的出色的结果,船边交货 ligand (FasL ) 的临床的使用被严重毒性作为 anticancer 药限制。死亡 ligands 的全身的毒性可以被使用编码膜界限死亡 ligands 的基因阻止,由指向的 transgene,通过也的表示指向了 transduction 或指向了抄写。肿瘤房间死亡的选择正式就职是有希望的 anticancer 策略。熔化蛋白质被熔化船边交货 ligand (FasL ) 的细胞外的领域到有选择地在肿瘤 endothelial 房间上指向 av3-integrins 的肽 arginine-glycine-aspartic 酸(RGD ) 创造。这研究的目的是在鼠科的 hepatocellular 癌(HCC ) 在肿瘤生长和幸存上评估 RGD-FasL 的效果肿瘤模型。有与 FasL 作为与那相比在 HCC 肿瘤模型上显示明显的镇压效果的 RGD-FasL 的处理(p < 0.05 ) 并且在这个模型在肿瘤生长延期上导致了更多的添加剂效果。RGD-FasL 处理显著地提高了老鼠幸存并且没引起有毒的效果,例如重量损失,机关失败,或另外的处理相关的毒性。Apoptosis 被流动 cytometric 分析和 TUNEL 试金检测;那些结果也证明 RGD-FasL 比 FasL 是为 H22 和 H9101 房间线的房间 apoptosis 的更多的有势力 inducer (p < 0.05 ) 。在结论, RGD-FasL 看起来是肿瘤房间死亡的低毒性的选择 inducer,它在现出症状之前的潜、临床的研究应得进一步的调查。而且,这条途径与治疗学的 recombinant 蛋白质为 complexing 目标 ligands 提供一种万用的技术。为了在 vivo,肿瘤和肝区分 FasL 的反肿瘤效果,纸巾被收获由染色的 Hematoxylin 和曙红(H&E ) 为坏死的房间,肿瘤房间,或 apoptotic 房间的证据检验。 | Zhongchen Liu Juan Wang Ping Yin Jinhua Qiu Ruizhen Liu Wenzhu Li Xin Fan Xiaofeng Cheng Caixia Chen Jiakai Zhang Guohong Zhuang | 2009 | Cellular & Molecular Immunology2009，6，4： | 1 |
| 9 | A novel assay for human papillomavirus testing among women in guizhou显示文摘 | Suzanne E B Na Wulan Ruizhen Li | | 0，，05： | 1 |
| 10 | Detection of allelic variation at the Wx locus with single-segment substitution lines in rice ( Oryza sativa L.)显示文摘 | Bin Teng Ruizhen Zeng Yicun Wang Ziqiang Liu Zemin Zhang Haitao Zhu Xiaohua Ding Wentao Li Guiquan Zhang | 2012 | Molecular Breeding2012，，： | 1 |
| 11 | Dynamic expression of nine QTLs for tiller number detected with single segment substitution lines in rice显示文摘 | Guifu Liu Ruizhen Zeng Haitao Zhu Zemin Zhang Xiaohua Ding Fangming Zhao Wentao Li Guiquan Zhang | 2009 | Theoretical and Applied Genetics2009，，3： | 1 |
| 12 | Extraction, characterization and antioxidant activities of polysaccharides from E. corneum gigeriae galli显示文摘 | Qingping Xiong Xia Li Ruizhen Zhou Hairong Hao Songlin Li Yi Jing Chun Zhu Qinghua Zhang Yingying Shi | 2014 | Carbohydrate Polymers2014，，： | 1 |
| 13 | Improved corrosion resistance on biodegradable magnesium by zinc and aluminum ion implantation显示文摘 | Ruizhen Xu Xiongbo Yang Kai Wong Suen Guosong Wu Penghui Li Paul K. Chu | 2012 | Applied Surface Science2012，，： | 1 |
| 14 | Regulation of artificial supramolecular transmembrane signal transduction by selenium-containing artificial enzyme receptors显示文摘Signal transduction across lipid bilayers is of profound importance in biological processes.In biological systems,natural enzymes mediate biochemical effects by binding to substrates and facilitating the conversion of external signals into physiological responses.Sequential transmission of biological signals from one enzyme to the next promotes signal transduction with feedforward and feedback mechanisms.Reconstructing these processes in an artificial system provides potential applications and offers a new way to understand fundamental biological processes in depth.However,the design of artificial signal transduction systems regulated by artificial enzyme receptors in a predictable and intelligent manner remains a challenge.Herein,benefiting from the polarity-regulated characteristics of Se-containing compounds with artificial glutathione peroxidase(GPx)activity,we constructed an artificial transmembrane signaling receptor with a Se-containing GPx-like recognition head group,a membrane-anchoring group,and a pre-enzyme end group.The artificial supramolecular signal transduction system containing such signal transduction receptors extends the range of signaling systems based on enzyme regulation,which provides a new way to study natural signal processes in cells and artificially regulated biological processes. | Shengda Liu Yunpeng Xing Tengfei Yan Yijia Li Ruizhen Tian Jinxing Hou Jiayun Xu Tingting Wang Junqiu Liu | 2023 | Nano Research2023，16，1： | 0 |
| 15 | Study on the dynamic variation of the secondary metabolites in Viscum coloratum using targeted metabolomics显示文摘Viscum coloratum(Kom.)Nakai is a well-known medicinal plant.However,the optimal harvest time for V.coloratum is unknown.Few studies were performed to analyze compound variation during storage and to improve post-harvest quality control.Our study aimed to comprehensively evaluate the quality of V.coloratum in different growth stages,and determine the dynamic variation of metabolites.Ultra-performance liquid chromatography tandem mass spectrometry was used to quantify 29 compounds in V.coloratum harvested in six growth periods,and the associated biosynthetic pathways were explored.The accumulation of different types of compounds were analyzed based on their synthesis pathways.Grey relational analysis was used to evaluate the quality of v.coloratum across different months.The compound variation during storage was analyzed by a high-temperature high-humidity accelerated test.The results showed that the quality of V.coloratum was the hightest in March,followed by November,and became the lowest in July.During storage,compounds in downstream steps of the biosynthesis pathway were first degraded to produce the upstream compounds and some low-molecular-weight organic acids,leading to an increase followed by a decrease in the content of some compounds,and resulted in a large gap during the degradation time course among different compounds.Due to the rapid rate and large degree of degradation,five compounds were tentatively designated as“early warning components”for quality control.This report provides reference for better understanding the biosynthesis and degradation of metabolites in V.coloratum and lays a theoretical foundation for rational application of V.coloratum and better quality control of V.coloratum during storage. | ZHANG Ruizhen DUAN Rong WANG Weiqing YU Zhiguo LI Yun ZHAO Yunli | 2023 | Chinese Journal of Natural Medicines2023，21，4： | 0 |
| 16 | Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing显示文摘Diabetic cardiomyopathy(DCM)is currently a progressive and nonstoppable complication in type 2 diabetic patients.Metabolic insults and insulin resistance are involved in its pathogenesis;however,the underlying mechanisms are still not clearly understood.Here we show that calcium dysregulation can be both a cause and a consequence of cardiac insulin resistance that leads to DCM.A western diet induces the development of DCM through at least three phases in mice,among which an early phase depends on impaired Thr^(484)-phosphorylation of sarcoplasmic/endoplasmic reticulum calcium ATPase 2a(SERCA2a)elicited by insulin resistance.Mutation of SERCA2a-Thr^(484) to a nonphosphorylatable alanine delays calcium re-uptake into the sarcoplasmic reticulum in the cardiomyocytes and decreases cardiac function at the baseline.Importantly,this mutation blunts the early phase of DCM,but has no effect on disease progression in the following phases.Interestingly,impairment of sarcoplasmic reticulum calcium re-uptake caused by the SERCA2a-Thr^(484) mutation inhibited processing of insulin receptor precursor through FURIN convertase,resulting in cardiac insulin resistance.Collectively,these data reveal a bidirectional relationship between insulin resistance and impairment of calcium homeostasis,which may underlie the early pathogenesis of DCM.Our findings have therapeutic implications for early intervention of DCM. | Chao Quan Sangsang Zhu Ruizhen Wang Jiamou Chen Qiaoli Chen Min Li Shu Su Qian Du Minjun Liu Hong-Yu Wang Shuai Chen | 2022 | Life Metabolism2022，1，1： | 0 |
| 17 | Time series canopy phenotyping enables the identification of genetic variants controlling dynamic phenotypes in soybean显示文摘Advances in plant phenotyping technologies are dramatically reducing the marginal costs of collecting multiple phenotypic measurements across several time points.Yet,most current approaches and best statistical practices implemented to link genetic and phenotypic variation in plants have been developed in an era of single-time-point data.Here,we used time-series phenotypic data collected with an unmanned aircraft system for a large panel of soybean(Glycine max(L.)Merr.)varieties to identify previously uncharacterized loci.Specifically,we focused on the dissection of canopy coverage(CC)variation from this rich data set.We also inferred the speed of canopy closure,an additional dimension of CC,from the time-series data,as it may represent an important trait for weed control.Genome-wide association studies(GWASs)identified 35 loci exhibiting dynamic associations with CC across developmental stages.The time-series data enabled the identification of 10 known flowering time and plant height quantitative trait loci(QTLs)detected in previous studies of adult plants and the identification of novel QTLs influencing CC.These novel QTLs were disproportionately likely to act earlier in development,which may explain why they were missed in previous single-time-point studies.Moreover,this time-series data set contributed to the high accuracy of the GWASs,which we evaluated by permutation tests,as evidenced by the repeated identification of loci across multiple time points.Two novel loci showed evidence of adaptive selection during domestication,with different genotypes/haplotypes favored in different geographic regions.In summary,the time-series data,with soybean CC as an example,improved the accuracy and statistical power to dissect the genetic basis of traits and offered a promising opportunity for crop breeding with quantitative growth curves. | Delin Li Dong Bai Yu Tian Ying-Hui Li Chaosen Zhao Qi Wang Shiyu Guo Yongzhe Gu Xiaoyan Luan Ruizhen Wang Jinliang Yang Malcolm J.Hawkesford James C.Schnable Xiuliang Jin Li-Juan Qiu | 2023 | Journal of Integrative Plant Biology2023，65，1： | 0 |
| 18 | Two New Identification Methods for Encephalitozoon cuniculi on Tissue Section显示文摘[Objective] The paper aimed to search new identification methods of Encephalitozoon cuniculi on tissue sections. [Method] Using improved Gram staining method and methyl green pyronin staining method,the pathological sections of sick rabbits were stained and identified. [Result]The pathological changes in brain tissue could be clearly observed on sections,but parasites were not examined in pathological brain tissues stained by common staining method. When the pathological section was stained by improved Gram staining method,the pathological changes in brain tissue were not only stained very clearly,but blue parasites were also found in brain tissues. The parasites in epithelioid cells were stained into purple ones by methyl green pyronin staining method. [Conclusion] The improved Gram staining method and methyl green pyronin staining method performed good staining effects of E. cuniculi in pathological sections,which were conducive to rapid diagnosis of encephalitozoonosis in rabbit. | Pan Yaoqian Li Ruizhen Song Gaojie Zhang Zhonghua Quan Suopei Fu Yanfang | 2016 | Animal Husbandry and Feed Science2016，8，2： | 0 |
| 19 | Superconductivity in chromium nitrides Pr3Cr10-xN11 with strong electron correlations显示文摘Exploration of superconductivity in Cr-based compounds has attracted considerable interest because only a few Cr-based superconductors(CrAs,A2Cr3As3 and ACr3As3(A=K,Rb,Cs,Na))have been discovered so far and they show an unconventional pairing mechanism.We report the discovery of bulk superconductivity at 5.25 K in chromium nitride in Pr3Cr10-xN11 with a cubic lattice structure.A relatively large upper critical field of Hc2(0)~12.6 T is determined,which is larger than the estimated Pauli-paramagnetic pair-breaking magnetic field.The material has a large electronic specific-heat coefficient of 170 mJ K^-2mol^-1-about 10 times larger than that estimated by the electronic structure calculation,which suggests that correlations between 3d electrons are very strong in Pr3Cr10-xN11,and thus quantum fluctuations might be involved.Electronic structure calculations show that the density of states at the Fermi energy are contributed predominantly by Cr 3d electrons,implying that the superconductivity results mainly from the condensation of Cr 3d electrons.Pr3Cr10-xN11 represents a rare example of possible unconventional superconductivity emerging in a 3D system with strong electron correlations.Nevertheless,clarification of the specific pairing symmetry needs more investigation. | Wei Wu Kai Liu Yanjie Li Zhenhai Yu Desheng Wu Yuting Shao Shihang Na Gang Li Ruizhen Huang Tao Xiang Jianlin Luo | 2020 | National Science Review2020，7，1： | 0 |
| 20 | Effect of Different Concentrations of Lipopolysaccharide on Expression of NF-κB and LAP in Mammary Epithelial Cells of Dairy Cow显示文摘The paper was to study the effects of different concentrations of lipopolysaccharide(LPS) on expression of nuclear factor Kappa B(NF-κB) and lingual antimicrobial peptide(LAP) gene in mammary epithelial cells of dairy cow.The mammary epithelial cells of dairy cow were stimulated by different concentrations(50,100,200,400 and 800 ng/mL) of LPS.The total RNA of cells was extracted after stimulation for 2,4,8,16,24,48 and 72 h,respectively,and the mRNA expression levels of NF-κB P65 and LAP were evaluated by real-time quantitative PCR.The results showed that the expression of NF-κB P65 and LAP mRNA treated with 400 ng / mL LPS for 72 h were the highest compared to the control group(P<0.01).The result confirmed that the expression activity of NF-κB was enhanced in inflammatory effects of mammary epithelial cells induced by LPS,which regulated the expression of defense gene LAP,with certain dose and time effects. | Cheng Lanling Cao Guifang Wen Shiyong Zhao Pengwei Tu Yong Jian Ruizhen Li Qi | 2014 | Animal Husbandry and Feed Science2014，6，1： | 0 |
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