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| 1 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 2 | Tile genetic epidemiology research of pri- mary liver cancer 显示文摘 | Meng Hui Liu Hongyan Cai Rulin Jiang Feng Jiang Qing five Lin Wenyao Shen Fumin | 2002 | Chinese journal of epidemiology2002，，6： | 1 |
| 3 | Area-efficient memristor spiking neural networks and supervised learning method显示文摘Dear editor,Memristors have attracted a lot of attention since HP Labs first reported their memristive devices[1].They have been employed in many fields,including non-volatile memory,image processing,and neuromorphic computing(2–4)In neuromorphic computing,memristors are usually used as synapses because they can store synaptic weights by their conductance(4)Most memristors have the structure of a crossbar array,which is area-efficient.With the cooperation of memristors and complementary metal oxide semiconductor(CMOS)neurons,it has become possible to implement lowpower and area-efficient hardware implementation for neural networks[5]. | Errui ZHOU Liang FANG Rulin LIU Zhensen TANG | 2019 | Science China(Information Sciences)2019，62，9： | 1 |
| 4 | Application of Hilbert-Huang Transform and SVM to Coal Gangue Interface Detection显示文摘 | Wei Liu Yuhua Yan Rulin Wang | 2011 | Journal of Computers2011，，6： | 1 |
| 5 | Advance in tolarence to heat of thermophiles显示文摘 | Ma Ting Liu Rulin | 2002 | Microbiology2002，29，2： | 1 |
| 6 | Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure显示文摘Peritoneal fibrosis together with increased capillaries is the primary cause of peritoneal dialysis failure.Mesothelial cell loss is an initiating event for peritoneal fibrosis.We find that the elevated glucose concentrations in peritoneal dialysate drive mesothelial cell pyroptosis in a manner dependent on caspase-3 and Gasdermin E,driving downstream inflammatory responses,including the activation of macrophages.Moreover,pyroptosis is associated with elevated vascular endothelial growth factor A and C,two key factors in vascular angiogenesis and lymphatic vessel formation.GSDME deficiency mice are protected from high glucose induced peritoneal fibrosis and ultrafiltration failure.Application of melatonin abrogates mesothelial cell pyroptosis through a MT1R-mediated action,and successfully reduces peritoneal fibrosis and angiogenesis in an animal model while preserving dialysis efficacy.Mechanistically,melatonin treatment maintains mitochondrial integrity in mesothelial cells,meanwhile activating m TOR signaling through an increase in the glycolysis product dihydroxyacetone phosphate.These effects together with quenching free radicals by melatonin help mesothelial cells maintain a relatively stable internal environment in the face of high-glucose stress.Thus,Melatonin treatment holds some promise in preserving mesothelium integrity and in decreasing angiogenesis to protect peritoneum function in patients undergoing peritoneal dialysis. | Hongxia Ruan Xuejuan Li Lina Zhou Zihan Zheng Rulin Hua Xu Wang Yuan Wang Yujie Fan Shuwen Guo Lihua Wang Shafiq ur Rahman Ziwei Wang Yuyuan Wei Shuangyan Yu Rongzhi Zhang Qian Cheng Jie Sheng Xue Li Xiaoyan Liu Ruqiang Yuan Xiaoyan Zhang Lihong Chen Guowang Xu Youfei Guan Jing Nie Hongqiang Qin Feng Zheng | 2024 | Science China(Life Sciences)2024，67，2： | 0 |
| 7 | Biomarkers (Alkanes )of the Xuanlong - Type Iron Deposits显示文摘The authors studied the biomarkers (alkanes) of eight iron ore samples from Nianpanshan and Dsbaodui of Pangjiabao and Longguan, Xuanhua, Hebei. These samples have higher nC15-nC20 contents, with main peaks at nC16, nC 17 and nC18, and contain abundant pristane and phytane. These results indicate that iron stromatolite and iron oncolites in orebodies are sedimentary structures of algal origin. Sedimentary iron accumulation mainly results from activity of blue algae. This study provides new valuable evidence for the origin of Xuanlong-type iron deposits. | Liu Zhili, Liu Xuexian, Li Pengfu Department of Biology, Nanjing University, Nanjing, Jiangsuand Du Rulin Hebei College of Geology, Shijiazhuang, Hebei Fei Zhenbi | 1995 | Acta Geologica Sinica(English Edition)1995，69，4： | 0 |
| 8 | Survey and Study of Soil Nutrients of Sugarcane Field in Southern Guangxi显示文摘To survey and analyze soil nutrients of sugarcane field in southern Guangxi and provide basic data for reasonable land use and scientific fertilization,combining GIS technology,a total of 498 samples of topsoil of typical soil types in southern Guangxi sugarcane planting areas were collected and soil nutrients were measured. Survey results indicate that the p H value of 95% soil in southern Guangxi is lower than 6. 5;acid soil is major soil type of sugarcane planting areas in southern Guangxi; the organic matter content is 6. 03- 44. 58 g / kg; alkali-hydrolyzable N is 14. 0- 175. 0 mg / kg; available P is 1. 7- 95. 0 mg / kg; available K is 11. 0- 358. 0 mg / kg; the content of most nutrients remains at medium level,and there is still a large gap with high-yield soil condition. In various trace elements,the average content of B is 0. 24 mg / kg,- 98% soil lacks B; the average content of available Mg is 62. 34 mg / kg and 69. 08% soil lacks Mg; the average content of active Ca is 592.68 mg / kg and the active Ca is relatively low in 54. 84% soil; the average content of available Zn is 0. 93 mg / kg,and 19. 08% soil lacks Zn;the average content of available Cu is 0. 65 mg / kg,and 7. 02% soil lacks Cu. It is concluded that the overall soil fertility of sugarcane planting areas in southern Guangxi is not high,the organic matter is relatively low,the content of rapidly available N,P and K is at medium or low level,the content of Fe and Mn is high,and the available Cu and available Zn of most soil remain at medium level. | Yan ZENG Jinsheng HUANG Rulin XIE Liuqiang ZHOU Yongxian LIU Yumo TAN Hongwei TAN | 2015 | Asian Agricultural Research2015，7，6： | 0 |
| 9 | Research on Synthetic Forsterite with Magnesite Tailings显示文摘High purity forsterite was prepared with magnesite tailings and quartz powder as starting materials. The influence of the preparation process on the physical properties of the synthetic forsterite was studied. The phase composition and the microstructure of the synthetic forsterite were analyzed by means of XRD and SEM. The results show that the composites with 63% MgO fired at1 670 ℃ exhibit the highest compact structure. | LIU Xijun XU Linlin LIU Zhao LIU Xiaolei XU Rulin WANG Juntao HU Shiping | 2018 | China's Refractories2018，27，2： | 0 |
| 10 | Identification of lipopolysaccharide-binding protein as a novel citrullinated autoantigen in rheumatoid arthritis显示文摘Background:A specific feature of the autoimmune response in rheumatoid arthritis(RA)is the presence of anti-citrullinated protein antibodies(ACPAs)in patient sera.These antibodies can appear several years before disease onset and are involved in the development of RA.Objective:We performed proteomic analysis by mass spectroscopy to identify novel citrullinated antigens and autoantibodies in RA patients.Methods:Polypeptides isolated from the sera of RA patients were identified by Orbitrap high-precision mass spectrometry and then citrulline-containing proteins were selected.The levels of ACPAs against these newly identified citrullinated autoantigens in sera of 100 RA patients and 50 healthy controls were determined by enzyme-linked immunosorbent assays.Results:A total of 135 proteins were identified in RA patients and the protein profile included 11 citrulline-containing antigens.Three of the 11 citrullinated proteins had been reported in previous studies.ACPAs against the novel citrullinated epitopes from these proteins were increased in sera from the RA patients compared with those from healthy controls.Autoantibodies against one of the citrullinated antigens,lipopolysaccharide-binding protein(LBP),was significantly increased in RA patients and associated with disease activities.The titer of anti-citrullinated LBP antibodies(anti-cLBP)was closely related to the infection incidence in RA patients.Conclusion:Serum protein analysis by high-precision proteomic technology is a feasible method to identify novel citrullinated epitopes in RA patients.Anti-cLBP antibodies are associated with disease severity and infection in RA patients. | Xiaozhen Zhao Yuling Chen Wen Wen Yongjing Cheng Ru Li Xu Liu Yuhui Li Rulin Jia Haiteng Deng Zhanguo Li Xiaolin Sun | 2022 | Rheumatology & Autoimmunity2022，2，1： | 0 |
| 11 | Temporal and Spatial Distribution of SARS-CoV-2 Aerosols in a Large-Scale Fangcang Shelter Hospital in Shanghai,China显示文摘The coronavirus disease 2019(COVID-19)pandemic caused by frequently mutating severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has had a worldwide impact.However,detailed data on the potential aerosol transmission of SARS-CoV-2 in real-world and controlled laboratory settings remain sparse.During the COVID-19 pandemic in Shanghai,China in 2022,samples were collected in a Fangcang shelter hospital,a large-scale temporary hospital rapidly built by converting the existing National Exhibition and Convention Center(Shanghai)into a health care facility.Aerosol samples at different sites and intervals around patients and in public areas,surface samples,and pharyngeal swab samples from corresponding patients were included.Samples were tested for SARS-CoV-2 using real-time quantitative polymerase chain reaction(RT-qPCR)assays,followed by sequencing if the cycle threshold(Ct)value was<30.The positivity rate for SARS-CoV-2 in aerosol samples was high in contaminated zones(37.5%,104/277),especially around the bed(41.2%,68/165)and near ventilation inlets(45.2%,14/31).The prevalence of SARS-CoV-2 around the bed,public areas,and air inlets of exhaust vents fluctuated and was closely related to the positivity rate among patients at corresponding sampling sites.Some surface samples of different personal protective equipment from medical staff had high positivity rates.Sixty sequences of joined ORF1ab and spike genes obtained from sixty samples represented two main clusters of Omicron SARS-CoV-2.There was consistency in virus sequences from the same patient and their environment,and the detected virus sequences matched those of virus strains in circulation during the collection periods,which indicated a high likelihood of cross-contamination in the Fangcang shelter hospital.In summary,the results provide a quantitative and real landscape of the aerosol transmission of SARS-CoV-2 and a patient-centered view of contamination in large and enclosed spaces and offer a useful guide for taking targeted measures to avoid nosocomial infections during the management of SARS-CoV-2 or other respiratory virus diseases in a Fangcang shelter hospital. | Jiafu Jiang Zhe Yin Jing Li Leili Jia Rulin He Wenhui Yang Jihu Yang Hang Fan Sen Zhang Yunfei Wang Zengming Zhao Haoran Peng Lizhong Li Yi Yang Shi-Yong Fan Rong Xiang Jianshu Guo Jinjin Wang Juanning Wei Fengling Zhou Ding Liu Ping Zhao Yujun Cui Yunxi Liu Dongsheng Zhou Gang Dong | 2023 | Engineering2023，，9： | 0 |
| 12 | Chemical upcycling of poly(lactide) plastic waste to lactate ester,lactide and new poly(lactide) under Mg-catalysis condition显示文摘Chemical upcycling of end-of-life poly(lactide) plastics to lactide,lactate ester and new poly(lactide)has been achieved by using magnesium bis[bis(trimethylsilyl)amide][Mg(HMDS)_(2)]as promoter.Mg(HMDS)2 showed high efficiency in L-lactide polymerization and poly(lactide) depolymerization.Mg(HMDS)_(2)/Ph_(2) CHOH catalytic system displayed high ring-opening selectivity and the characteristic of immortal polymerization.Taking advantage of transesterification,depolymerizations of end-oflife poly(lactide) plastics to lactate ester (polymer to value-added chemicals) and lactide (polymer to monomer) were achieved with high yields.Besides,a new“depolymerization-repolymerization”strategy was proposed to directly transform poly(lactide) into new poly(lactide).This work provides a theoretical basis for the design of polymerization and depolymerization catalysts and promotes the development of degradable polymers. | Xianyue Zhou Qiuyang Liu Guangqiang Xu Rulin Yang Hongguang Sun Qinggang Wang | 2023 | Chinese Chemical Letters2023，34，10： | 0 |
| 13 | Stimulating and harnessing circularly polarized luminescence of helically assembled carbonized polymer dots via interfacial dynamics显示文摘Stimulating and harnessing circularly polarized luminescence(CPL)is not only a sine qua non for fundamentally unveiling chirogenesis in physical chemistry,but also a pivotal prerequisite for implementation of such phenomenon in research fields including chiral optoelectronics and theranostics.Herein,red-emissive carbonized polymer dots(CPDs)-based helical structures were synthesized in this work via biomolecule-tailored organic–inorganic co-assembly strategy.The surface statesrelated chirality exhibits enhanced circular dichroism(CD)and CPL activities with anisotropic factors as high as gCD,max=5.4×10^(−3) and glum,max=1.5×10^(−2),respectively.The obtained CPL signals can be further manipulated in an excitationdependent manner,indicating that a synergistic-competition phenomenon exists between configurational chirality and intermolecular energy-transfer dynamics,which is further supported by simulations based on density function theory(DFT).Such tunable CPL behavior triggers revolutionary designs and applications of these chiral CPDs into the realm of chirality-related biological issues and next-generation chiral optoelectronics. | Jiaying Lin Rulin Liu Peixian Chen Yangfei Lv Junjie Hao Meijuan Chen Dongxiang Zhang Ruikun Pan Yiwen Li Xi Zhu Tingchao He Jiaji Cheng | 2023 | Aggregate2023，4，4： | 0 |
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