|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Artificial intelligence in healthcare:past,present and future显示文摘Artificial intelligence(AI)aims to mimic human cognitive functions.It is bringing a paradigm shift to healthcare,powered by increasing availability of healthcare data and rapid progress of analytics techniques.We survey the current status of AI applications in healthcare and discuss its future.AI can be applied to various types of healthcare data(structured and unstructured).Popular AI techniques include machine learning methods for structured data,such as the classical support vector machine and neural network,and the modern deep learning,as well as natural language processing for unstructured data.Major disease areas that use AI tools include cancer,neurology and cardiology.We then review in more details the AI applications in stroke,in the three major areas of early detection and diagnosis,treatment,as well as outcome prediction and prognosis evaluation.We conclude with discussion about pioneer AI systems,such as IBM Watson,and hurdles for real-life deployment of AI. | Fei Jiang Yong Jiang Hui Zhi Yi Dong Hao Li Sufeng Ma Yilong Wang Qiang Dong Haipeng Shen Yongjun Wang | 2017 | Stroke & Vascular Neurology2017，2，4： | 76 |
| 2 | Research on trusted computing and its development显示文摘Trusted computing is a novel technology of information system security. It has become a new tide in worldwide information security area and achieved inspiring accomplishment. In China, the initiative research of trusted computing is not late, and the achievements are plentiful and substantial. Our country is in the front rank of the world in trusted computing. This paper comprehensively illustrates the recent development in theory and technology of trusted computing, introduces some improvements in trusted computing in our country, and proposes our opinions and viewpoints towards the existing problems in trusted computing and its future development. | SHEN ChangXiang ZHANG HuanGuo WANG HuaiMin WANG Ji ZHAO Bo YAN Fei YU FaJiang ZHANG LiQiang XU MingDi | 2010 | Science China(Information Sciences)2010，53，3： | 37 |
| 3 | Minimal invasive microscopic tooth preparation in esthetic restoration: a specialist consensus显示文摘By removing a part of the structure,the tooth preparation provides restorative space,bonding surface,and finish line for various restorations on abutment.Preparation technique plays critical role in achieving the optimal result of tooth preparation.With successful application of microscope in endodontics for>30 years,there is a full expectation of microscopic dentistry.However,as relatively little progress has been made in the application of microscopic dentistry in prosthodontics,the following assumptions have been proposed:Is it suitable to choose the tooth preparation technique under the naked eye in the microscopic vision?Is there a more accurate preparation technology intended for the microscope?To obtain long-term stable therapeutic effects,is it much easier to achieve maximum tooth preservation and retinal protection and maintain periodontal tissue and oral function health under microscopic vision?Whether the microscopic prosthodontics is a gimmick or a breakthrough in obtaining an ideal tooth preparation should be resolved in microscopic tooth preparation.This article attempts to illustrate the concept,core elements,and indications of microscopic minimally invasive tooth preparation,physiological basis of dental pulp,periodontium and functions involved in tool preparation,position ergonomics and visual basis for dentists,comparison of tooth preparation by naked eyes and a microscope,and comparison of different designs of microscopic minimally invasive tooth preparation techniques.Furthermore,a clinical protocol for microscopic minimally invasive tooth preparation based on target restorative space guide plate has been put forward and new insights on the quantity and shape of microscopic minimally invasive tooth preparation has been provided. | Haiyang Yu Yuwei Zhao Junying Li Tian Luo Jing Gao Hongchen Liu Weicai Liu Feng Liu Ke Zhao Fei Liu Chufan Ma Juergen MSetz Shanshan Liang Lin Fan Shanshan Gao Zhuoli Zhu Jiefei Shen Jian Wang Zhimin Zhu Xuedong Zhou | 2019 | International Journal of Oral Science2019，11，4： | 25 |
| 4 | The Chinese Society of Clinical Oncology(CSCO)clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.To develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the guidelines.Based on the findings of evidencebased medicine in China and abroad,domestic experts have iteratively developed these guidelines to provide proper management of NPC.Overall,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC. | Ling-Long Tang Yu-Pei Chen Chuan-Ben Chen Ming-Yuan Chen Nian-Yong Chen Xiao-Zhong Chen Xiao-Jing Du Wen-Feng Fang Mei Feng Jin Gao Fei Han Xia He Chao-Su Hu De-sheng Hu Guang-Yuan Hu Hao Jiang Wei Jiang Feng Jin Jin-Yi Lang Jin-Gao Li Shao-Jun Lin Xu Liu Qiu-Fang Liu Lin Ma Hai-Qiang Mai Ji-Yong Qin Liang-Fang Shen Ying Sun Pei-Guo Wang Ren-Sheng Wang Ruo-Zheng Wang Xiao-Shen Wang Ying Wang Hui Wu Yun-Fei Xia Shao-Wen Xiao Kun-Yu Yang Jun-Lin Yi Xiao-Dong Zhu Jun Ma | 2021 | Cancer Communications2021，41，11： | 22 |
| 5 | Isolation,characterization,and phylogenic analysis of three new severe fever with thrombocytopenia syndrome bunyavirus strains derived from Hubei Province,China显示文摘Hubei Province is a major epidemic area of severe fever with thrombocytopenia syndrome bunyavirus(SFTSV) in China. However, to date, a few SFTSV strains have been isolated from Hubei Province, preventing effective studies of epidemic outbreaks. Here, we report three confirmed patients(2015–2016) with typical symptoms of severe fever with thrombocytopenia syndrome disease(SFTS) who were farmers resident in different regions in Hubei Province. Three new SFTSV strains were isolated from the serum samples of each patient. Characterization of viral growth properties showed that there were no significant differences in virus production. All strains were completely sequenced, and phylogenetic analysis showed that unlike the other strains from Hubei province, which belonged to the SFTSV C3 genotype, one of the three strains belonged to the SFTSV C2 genotype. These results suggested that multiple SFTSV genotypes have been circulating in Hubei Province, providing insights into SFTSV evolution and improving our understanding of SFTSV prevalence in Hubei Province. | Yanfang Zhang Shu Shen Junming Shi Zhengyuan Su Mingyue Li Wenjing Zhang Mengmeng Li Zhihong Hu Cheng Peng Xin Zheng Fei Deng | 2017 | Virologica Sinica2017，32，1： | 21 |
| 6 | Effect of curettage and copper wire on rabbit endometrium: a novel rabbit model of endometrial mechanical injury显示文摘它仍然是的背景几乎,为周期性的培植失败和怀孕损失的一种无助的状况目前由子宫内膜的损害引起了。这研究的目的是开发能为这困难的临床的 predicament.Methods 提供一个研究平台的子宫内膜的机械损害的一个兔子模型三个实验被进行。实验 1:在子宫角并且铜丝在一只角在刮术(双损害) 以后插入的刮术。组织学的变化在 0 点被监视, 24, 48, 72 个小时,以及在在操作以后的 1 和 2 个星期内。实验 2:指导在另外的角在一只角和双损害插入的铜丝。在两只角的电线在 2 个星期以后被移开。组织学的变化在电线移动以后在 0, 1 和 2 个星期被记录。实验 3:在一只角的双损害过程被执行,电线在 2 个星期以后被移开;另一只角被仍然是用作控制的正常。组织学的变化被记录,组织区域被测量,并且增长索引 PI, %) 在电线移动以后在 1,2, 4 和 8 个星期被计算,实验揭示了的 respectively.Results 由简单刮术或铜丝的受伤子宫内膜能是,这充分修理了。当子宫内膜的新生被双损害严重地损害时,子宫内膜和子宫的洞的两个区域减少了(P 0.05 ) ;两 PI 腺上皮并且在 4 个星期(P 0.05 ) 增加并且到达,但是由 8 weeks.Conclusion 归还了这研究最大值的 stromal 房间证明子宫内膜的损害的一个兔子模型能有效地与可比较的临床的索引通过 curettaqe 和铜丝的一个双损害过程被建立。 | LI Li SHIjing ZHANG Qiu-fang YAN Jie YAN Li-ying SHEN Fei QIAO Jie FENG Huai-liang | 2011 | Chinese Medical Journal2011，，11： | 20 |
| 7 | Expression changes and bioinformatic analysis of Wallerian degeneration after sciatic nerve injury in rat显示文摘Wallerian degeneration (WD) remains an important research topic. Many genes are differentially expressed during the process of WD, but the precise mechanisms responsible for these differentiations are not completely understood. In this study, we used microarrays to analyze the expression changes of the distal nerve stump at 0, 1, 4, 7, 14, 21 and 28 days after sciatic nerve injury in rats. The data revealed 6 076 differentially-expressed genes, with 23 types of expression, specifically enriched in genes associated with nerve development and axonogenesis, cytokine biosynthesis, cell differentiation, cytokine/chemokine production, neuron differentiation, cytokinesis, phosphorylation and axon regeneration. Kyoto Encyclopedia of Genes and Genomes pathway analysis gave findings related mainly to the MAPK signaling pathway, the Jak-STAT signaling pathway, the cell cycle, cytokine-cytokine receptor interaction, the p53 signaling pathway and the Wnt signaling pathway. Some key factors were NGF, MAG, CNTF, CTNNA2, p53, JAK2, PLCB1, STAT3, BDNF, PRKC, collagen II, FGF, THBS4, TNC and c-Src, which were further validated by real-time quantitative PCR, Western blot, and immunohistochemistry. Our findings contribute to a better understanding of the functional analysis of differentially-expressed genes in WD and may shed light on the molecular mechanisms of nerve degeneration and regeneration. | Dengbing Yao Meiyuan Li Dingding Shen Fei Ding Shibi Lu Qing Zhao Xiaosong Gu | 2013 | Neuroscience Bulletin2013，29，3： | 18 |
| 8 | Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration显示文摘 | Hu Wang Hongna Zuo Jin Liu Fei Wen Yawei Gao Xudong Zhu Bo Liu Feng Xiao Wengong Wang Gang Huang Bin Shen Zhenyu JU | 2018 | Cell Research2018，28，10： | 16 |
| 9 | Mechanical properties of hot-pressed high-entropy diboride-based ceramics显示文摘High-entropy ceramics attract more and more attention in recent years.However,mechanical properties especially strength and fracture toughness for high-entropy ceramics and their composites have not been comprehensively reported.In this work,high-entropy(Ti0.2Zr0.2Hf0.2Nb0.2Ta 0.2)B2(HEB)monolithic and its composite containing 20 vol%SiC(HEB–20SiC)are prepared by hot pressing.The addition of SiC not only accelerates the densification process but also refines the microstructure of HEB,resulting in improved mechanical properties.The obtained dense HEB and HEB–20SiC ceramics hot pressed at 1800℃exhibit four-point flexural strength of 339±17 MPa and 447±45 MPa,and fracture toughness of 3.81±0.40 MPa·m1/2 and 4.85±0.33 MPa·m1/2 measured by single-edge notched beam(SENB)technique.Crack deflection and branching by SiC particles is considered to be the main toughening mechanisms for the HEB–20SiC composite.The hardness Hv0.2 of the sintered HEB and HEB–20SiC ceramics is 23.7±0.7 GPa and 24.8±1.2 GPa,respectively.With the increase of indentation load,the hardness of the sintered ceramics decreases rapidly until the load reaches about 49 N,due to the indentation size effect.Based on the current experimental investigation it can be seen that the room temperature bending strength and fracture toughness of the high-entropy diboride ceramics are within ranges commonly observed in structure ceramics. | Ji-Xuan Liu Xiao-Qin Shen Yue Wu Fei Li Yongcheng Liang Guo-Jun Zhang | 2020 | Journal of Advanced Ceramics2020，9，4： | 16 |
| 10 | Experimental exploration and research prospect of physical bases and functional characteristics of meridians显示文摘The physical basis of meridians and acupoints (acupuncture points) is in a complex system mainly of connective tissue and interwoven with the blood capillaries, nerves, lymph vessels,etc. Elements of Ca, P, K, Fe, Zn, Mn, etc are found concentrated in the deep connective tissue structures in locations corresponding to acupoints. On this physical basis, the specific waveband of high efficiency for transmission of infrared rays exists in the collagenous fibre in a liquid crystal state. The development direction and new idea of researching on acupuncture and meridians are discussed. | Lun Fei Huansheng Cheng Deheng Cai Shixun Yang Jianrong Xu Eryu Chen Ruishan Dang Guanghong Ding Xueyong Shen Yi Tang et al. | 1998 | Chinese Science Bulletin1998，43，15： | 15 |
| 11 | AKT-modified autologous intracoronary mesenchymal stem cells prevent remodeling and repair in swine infarcted myocardium显示文摘成年骨头的背景移植导出髓的间充质的干细胞(MSC ) 为心脏的修理作为策略被建议了后面的心肌的损坏。然而,代替失去的心肌层的房间移植策略被无能限制交付抵抗 peritransplantation 接枝房间死亡的大量房间。因此,我们开始孤立并且膨胀成年的猪骨头,并且设计这些房间到 overexpress AKT1 (蛋白质 kinase B )导出髓的 MSC ,为了测试假设,那 AKT1 设计了 MSC 对 apoptosis 更抵抗并且能在移植以后提高心脏的修理进 ischemic 猪 heart.Methods CDS ( AKT1 的规定领域) AKT1-cDNA 碎片被放大,并且 MSC 是有 pCDH1-AKT1 shuttling plasmid 的 transfected 追随者合成。西方的弄污分析和即时反向的抄写聚合酶链反应(RT-PCR ) 被执行。心肌的梗塞(Ml ) 模型在 Meishan 猪被构造,并且心脏的功能被磁性的回声成像(MRI ) 评估大小和 4 个星期以后的 echocardiography。所有猪被分到四个组:控制(A) , DMEM (B) , MSC (C) ,和 AKT-transfected (D) 。MSC 是有 AKT1 基因,和自体同源的标记 BrdU 的干细胞的 transfected | YU Yun-sheng SHEN Zhen-ya YE Wen-xue HUANG Hao-yue HUA Fei CHEN Yi-huan CHEN Ke LAO Wei-jie TAO Li | 2010 | Chinese Medical Journal2010，，13： | 15 |
| 12 | Liver Enzymes Concentrations Are Closely Related to Pre-diabetes:Findings of the Shanghai Diabetes Study Ⅱ (SHDS Ⅱ)显示文摘Objective To investigate the relationship of liver enzymes with hyperglycemia in a large population in Shanghai and identify the association between liver enzymes and insulin resistance.Methods A total of 3 756 participants were enrolled.Each participant underwent an oral glucose tolerance test and completed a questionnaire.Anthropometric indices were recorded and serum samples were collected for measurement.Results Liver enzymes concentrations were independently associated with i-IGT,IFG+IGT,and diabetes.With the increase of ALT and GGT concentrations,ORs for i-IGT,IFG+IGT,and diabetes increased gradually.By comparing patients in the highest quartile of GGT concentrations or ALT concentrations with those in the lowest quartile (Q1),ORs for i-IGT,IFG+IGT,or diabetes was significant after adjustment.Both ALT and GGT concentrations were linearly correlated with HOMA-IR and independently associated with HOMA-IR [ALT OR (95% CI):2.56 (1.51-4.34) P=0.00;GGT OR (95% CI):2.66 (1.53-4.65) P=0.00].Conclusion Serum ALT and GGT concentrations were closely related to pre-diabetes and diabetes in the Shanghai population and positively associated with insulin resistance. | GAO Fei PAN Jie Min HOU Xu Hong FANG Qi Chen LU Hui Juan TANG Jun Ling GU Hui Lin PAN Zhi Jian YAO You Hua SHEN Wei Zhen JIA Wei Ping | 2012 | Biomedical and Environmental Sciences2012，25，1： | 15 |
| 13 | Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1显示文摘Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid peroxidation in an iron-and ROS-dependent manner. Celastrol, a natural bioactive triterpenoid extracted from Tripterygium wilfordii, shows effective anti-fibrotic and anti-inflammatory activities in multiple hepatic diseases. However, the exact molecular mechanisms of action and the direct protein targets of celastrol in the treatment of liver fibrosis remain largely elusive. Here, we discover that celastrol exerts anti-fibrotic effects via promoting the production of reactive oxygen species(ROS) and inducing ferroptosis in activated hepatic stellate cells(HSCs). By using activity-based protein profiling(ABPP) in combination with bio-orthogonal click chemistry reaction and cellular thermal shift assay(CETSA), we show that celastrol directly binds to peroxiredoxins(PRDXs), including PRDX1, PRDX2, PRDX4 and PRDX6,through the active cysteine sites, and inhibits their anti-oxidant activities. Celastrol also targets to heme oxygenase 1(HO-1) and upregulates its expression in activated-HSCs. Knockdown of PRDX1, PRDX2,PRDX4, PRDX6 or HO-1 in HSCs, to varying extent, elevated cellular ROS levels and induced ferroptosis. Taken together, our findings reveal the direct protein targets and molecular mechanisms via which celastrol ameliorates hepatic fibrosis, thus supporting the further development of celastrol as a promising therapeutic agent for liver fibrosis. | Piao Luo Dandan Liu Qian Zhang Fan Yang Yin-Kwan Wong Fei Xia Junzhe Zhang Jiayun Chen Ya Tian Chuanbin Yang Lingyun Dai Han-Ming Shen Jigang Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 14 |
| 14 | Synthesis and anti-tumor activity of all-trans retinoic acid derivatives显示文摘一系列 retinoate 和 retinamide 衍生物被设计,综合,并且他们的反肿瘤活动在由 MTT 和流动 cytometry 试金(FCM ) 的 NB4 被调查。所有混合物证明 cytotoxicity,特别混合物 1a 和 1d 比另外的衍生物和 all-trans retinoic 酸(ATRA ) 展出了更高的 cytotoxicity。而且,复合 1d 能高效地导致 NB4 房间线区别。 | Juan Shen Jing Bo Shi Fei Hu Chen Yuan Wang Jing Jing Ruan Yan Huang | 2009 | Chinese Chemical Letters2009，20，7： | 13 |
| 15 | Plasma neutrophil-gelatinase-associated lipocalin and cystatin C could early diagnose contrast-induced acute kidney injury in patients with renal insufficiency undergoing an elective percutaneous coronary intervention显示文摘 | LIU Xiao-li WANG Zhi-jian YANG Qing YU Miao SHEN Hua NIE Bin HAN Hong-ya GAO Fei ZHOU Yu-jie | 2012 | Chinese Medical Journal2012，，6： | 12 |
| 16 | Homogenization heat treatment of 2099 Al–Li alloy显示文摘The microstructure evolution and composition distribution of as-cast and homogenized 2099 aluminum– lithium(Al–Li) alloy were studied by optical microscopy(OM), differential thermal analysis(DTA), scanning electron microscopy(SEM), energy dispersive spectrometry(EDS), area and line scanning, X-ray diffraction(XRD), and Vickers microhardness test methods. The results show that severe dendrite exists in the as-cast alloy. Cu, Zn, Mn, and Mg distribute unevenly from the grain boundary to inside. The low-melting point nonequilibrium eutectic phases dissolve into the matrix during the first-step homogenization, whereas the melting point of residual eutectic phases is elevated. After the second-step homogenization, most of the remaining eutectic phases dissolve into the matrix, except a small amount of Al–Cu–Fe phases. An optimized homogenization process of the 2099 Al–Li alloy is developed(515 °C 9 18 h ? 525 °C 9 16 h), which shows a good agreement with the homogenization kinetic analysis results. | Fei Zhang Jian Shen Xiao-Dong Yan Jian-Lin Sun Xiao-Long Sun Yin Yang | 2014 | Rare Metals2014，33，1： | 12 |
| 17 | Accuracy of physical examination, ultrasonography, and magnetic resonance imaging in predicting response to neo-adjuvant chemotherapy for breast cancer显示文摘 | CHEN Man ZHAN Wei-wei HAN Bao-san FEI Xiao-chun JIN Xiao-long CHAI Wei-min WANG Deng-bing SHEN Kun-wei WANG Wen-ping | 2012 | Chinese Medical Journal2012，，11： | 12 |
| 18 | Endometrial membrane organoids from human embryonic stem cell combined with the 3D Matrigel for endometrium regeneration in asherman syndrome显示文摘Asherman’s syndrome(AS),a leading cause of uterine infertility worldwide,is characterized by scarring of the uterine surfaces lacking endometrial epithelial cells,which prevents endometrial regeneration.Current research on cell therapy for AS focuses on mesenchymal and adult stem cells from the endometrium.However,insufficient number,lack of purity,and rapid senescence of endometrial epithelial progenitor cells(EEPCs)during experimental processes restrict their use in cell therapies.In this study,we induced human embryonic stem cells-9(H9-ESC)into EEPCs by optimizing the induction factors from the definitive endoderm.EEPCs,which act as endometrial epithelial cells,accompanied by human endometrial stromal cells provide a niche environment for the development of endometrial membrane organoids(EMOs)in an in vitro 3D culture model.To investigate the function of EMOs,we transplanted tissue-engineered constructs with EMOs into an in vivo rat AS model.The implantation of EMOs into the damaged endometrium facilitates endometrial regeneration and angiogenesis.Implanting EMOs developed from human embryonic stem cells into the endometrium might prove useful for“endometrial re-engineering”in the treatment of Asherman’s syndrome. | Xiuxiu Jiang Xingmiao Li Xiangwei Fei Jiajie Shen Jianhua Chen Meijun Guo Yangyang Li | 2021 | Bioactive Materials2021，6，11： | 11 |
| 19 | Inflammatory biomarkers and cerebral small vessel disease:a community-based cohort study显示文摘Background and purpose Although inflammation has been proposed to be a candidate risk factor for cerebral small vessel disease(CSVD),previous findings remain largely inconclusive and vary according to disease status and study designs.The present study aimed to investigate possible associations between inflammatory biomarkers and MRI markers of CSVD.Methods A group of 15 serum inflammatory biomarkers representing a variety of those putatively involved in the inflammatory cascade was grouped and assessed in a cross-sectional study involving 960 stroke-free subjects.The biomarker panel was grouped as follows:systemic inflammation(high-sensitivity C reactive protein(hsCRP),interleukin 6 and tumour necrosis factorα),endothelial-related inflammation(E-selectin,P-selectin,intercellular adhesion molecule 1,vascular cell adhesion molecule 1(VCAM-1),CD40 ligand,lipoprotein-associated phospholipase A2,chitinase-3-like 1 protein and total homocysteine(tHCY))and media-related inflammation(matrix metalloproteinases 2,3 and 9,and osteopontin).The association(s)between different inflammatory groups and white matter hyperintensity(WMH),lacunes,cerebral microbleeds(CMBs),enlarged perivascular space(PVS)and the number of deep medullary veins(DMVs)were investigated.Results High levels of serum endothelial-related inflammatory biomarkers were associated with both increased WMH volume(R^(2)=0.435,p=0.015)and the presence of lacunes(R^(2)=0.254,p=0.027).Backward stepwise elimination of individual inflammatory biomarkers for endothelial-related biomarkers revealed that VCAM-1 was significant for WMH(β=0.063,p=0.005)and tHCY was significant for lacunes(β=0.069,p<0.001).There was no association between any group of inflammatory biomarkers and CMBs or PVS.Systemic inflammatory biomarkers were associated with fewer DMVs(R^(2)=0.032,p=0.006),and backward stepwise elimination of individual systemic-related inflammatory biomarkers revealed that hsCRP(β=−0.162,p=0.007)was significant.Conclusion WMH and lacunes were associated with endothelial-related inflammatory biomarkers,and fewer DMVs were associated with systemic inflammation,thus suggesting different underlying inflammatory processes and mechanisms. | Ding-Ding Zhang Yuan Cao Jing-Yu Mu Yi-Ming Liu Feng Gao Fei Han Fei-Fei Zhai Li-Xin Zhou Jun Ni Ming Yao Ming-Li Li Zheng-Yu Jin Shu-Yang Zhang Li-Ying Cui Yong Shen Yi-Cheng Zhu | 2022 | Stroke & Vascular Neurology2022，7，4： | 11 |
| 20 | Ultrathin Al2O3-coated reduced graphene oxide membrane for stable lithium metal anode显示文摘Lithium(Li) metal has been considered as the most attractive anode materials for Li-ion batteries(LIBs)due to its high theoretic specific capacity. The formation of unstable solid electrolyte interphase(SEI) and dendritic Li on the metal anode, however, hindered its practical application. Herein, to address the issues, a Li-free electrode with ultrathin Al_2O_3 coated on reduced graphene oxide(rGO) membrane that covers a Cu foil current collector was developed. The composite electrode exhibits excellent interfacial protection of lithium metal deposited between Cu foil and rGO electrochemically. Firstly, it affords good Li^+ permeability from the electrolyte. Secondly, the ultrathin Al_2O_3 has sufficient mechanical strength to inhibit the penetration of Li dendrite. Li metal was observed uniformly deposited between rGO membrane and Cu collector, and stable cycle performance of Li plating/stripping with Coulombic efficiency of ~91.75% at the 100 th cycle is achieved in organic carbonate electrolyte without any additives. | Fan Zhang Fei Shen ZhaoYang Fan Xin Ji Bin Zhao ZhouTing Sun YingYing Xuan XiaoGang Han | 2018 | Rare Metals2018，37，6： | 11 |
您所在的机构暂未开通此部分的功能，请联系管理员