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| 1 | Diagenetic fluids evolution and genetic mechanism of tight sandstone gas reservoirs in Upper Triassic Xujiahe Formation in Sichuan Basin, China显示文摘The reservoirs of the Upper Triassic Xujiahe Formation in Sichuan Basin have the characteristics of low compositional maturity, low contents of cements and medium textural maturity. The general physical properties of the reservoirs are poor, with low porosity and low permeability, and there are only a few reservoirs with medium porosity and low permeability in local areas. Based on the diagenetic mineral association, a diagenetic sequence of cements is established: early calcites (or micrite siderites) →first quartz overgrowth→chlorite coatings→dissolution of feldspars and debris→chlorite linings→ second quartz overgrowth (quartz widen or filled in remain intergranular pores and solution pores)→dissolution→third quartz overgrowth (quartz filled in intergranular and intragranular solution pores)→intergrowth (ferro) calcites→dolomites→ferro (calcites) dolomites→later dissolution→veins of quartz and calcites formation. Mechanical compaction is the main factor in making the reservoirs tight in the basin, followed by the second and third quartz overgrowth. In a long-term closed system, only feld-spars and some lithic fragments are dissolved by diagenetic fluids, while intergranular cements such as quartz and calcit are not dissolved and thus have little influence on the porosity of the Xujiahe Formation. This is the third factor that may have kept the sandstones of Xujiahe Formation tight finally. The hydrocarbon was extensively generated from organic materials after the second quartz overgrowth, and selectively entered favorable reservoirs to form tight sandstone gas reservoirs. | ZHU RuKai ZOU CaiNeng ZHANG Nai WANG XueSong CHENG Rong LIU LiuHong ZHOU ChuanMin SONG LiHong | 2008 | Science China Earth Sciences2008，51，9： | 29 |
| 2 | Features and origin time of Mesozoic strike-slip structures in the Yilan-Yitong Fault Zone显示文摘The NE-striking Yilan-Yitong Fault Zone(YYFZ) with a length of ca. 900 km is an important major fault zone in northeastern China. Its origin has been a controversial issue for a long time. Detailed field investigation and comprehensive analyses show that strike-slip faults or ductile shear belts exist as the origination structures on the both shoulders of the Cretaceous-Paleogene grabens. These strike-slip structures are dominated by brittle transcurrent faults, and appear as ductile shear belts only in the Weiyuanpu-Yehe and Shulan parts in the south and middle of the fault zone, respectively. The shear belts strike NE-SW and show steep mylonitic foliation and gentle mineral elongation lineation. Outcrop structures, microstructures and quartz c-axis fabrics demonstrate a sinistral shear sense with minor reverse component for the ductile shear belts. The microstructures suggest deformation temperatures of 400–450°C for the Weiyuanpu-Yehe shear belts and 350–400°C for the Shulan shear belt. A series of zircon U-Pb dating results for deformed and undeformed plutons or dikes in the shear belts constrain the strike-slip motion to the time between 160 and 126 Ma. It is further inferred from ages of main geological events in this region that the fault zone originated in the earliest Early Cretaceous. It is suggested therefore that the southern and middle parts of the Tan-Lu Fault Zone, which originated in Middle Triassic, propagated into northeastern China along the sinistral YYFZ under the earliest Early Cretaceous regional compression that is referred to as the Yanshan B event. The earliest Early Cretaceous initiation of the YYFZ results from both the high-speed oblique subduction of the Izanagi Plate and the final closure of the Mongol-Okhotsk Ocean, but the Izanagi Plate subduction played a major dynamic role in the fault zone origin. | GU ChengChuan ZHU Guang ZHAI MingJian LIN ShaoZe SONG LiHong LIU Bei | 2016 | Science China(Information Sciences)2016，59，12： | 10 |
| 3 | Expert consensus on early childhood caries management显示文摘Early childhood caries(ECC)is a significant chronic disease of childhood and a rising public health burden worldwide.ECC may cause a higher risk of new caries lesions in both primary and permanent dentition,affecting lifelong oral health.The occurrence of ECC has been closely related to the core microbiome change in the oral cavity,which may be influenced by diet habits,oral health management,fluoride use,and dental manipulations.So,it is essential to improve parental oral health and awareness of health care,to establish a dental home at the early stage of childhood,and make an individualized caries management plan.Dental interventions according to the minimally invasive concept should be carried out to treat dental caries.This expert consensus mainly discusses the etiology of ECC,caries-risk assessment of children,prevention and treatment plan of ECC,aiming to achieve lifelong oral health. | Jing Zou Qin Du Lihong Ge Jun Wang Xiaojing Wang Yuqing Li Guangtai Song Wei Zhao Xu Chen Beizhan Jiang Yufeng Mei Yang Huang Shuli Deng Hongmei Zhang Yanhong Li Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，3： | 5 |
| 4 | The combination of chidamide with the CHOEP regimen in previously untreated patients with peripheral T-cell lymphoma: a prospective, multicenter, single arm, phase 1b/2 study显示文摘Objective:To assess the efficacy and safety of the novel histone deacetylase inhibitor,chidamide,in combination with cyclophosphamide,doxorubicin,vincristine,etoposide,and prednisone(Chi-CHOEP)for untreated peripheral T-cell lymphoma(PTCL).Methods:A prospective,multicenter,single arm,phase 1 b/2 study was conducted.A total of 128 patients with untreated PTCL(18–70 years of age)were enrolled between March 2016 and November 2019,and treated with up to 6 cycles with the Chi-CHOEP regimen.In the phase 1 b study,3 dose levels of chidamide were evaluated and the primary endpoint was determination of the maximumtolerated dose and recommended phase 2 dose(RP2 D).The primary endpoint of the phase 2 study was 2-year progression-free survival(PFS).Results:Fifteen patients were enrolled in the phase 1 b study and the RP2 D for chidamide was determined to be 20 mg,twice a week.A total of 113 patients were treated at the RP2 D in the phase 2 study,and the overall response rate was 60.2%,with a complete response rate of 40.7%.At a median follow-up of 36 months,the median PFS was 10.7 months,with 1-,2-,and 3-year PFS rates of 49.9%,38.0%,and 32.8%,respectively.The Chi-CHOEP regimen was well-tolerated,with grade 3/4 neutropenia occurring in approximately two-thirds of the patients.No unexpected adverse events(AEs)were reported and the observed AEs were manageable.Conclusions:This large cohort phase 1 b/2 study showed that Chi-CHOEP was well-tolerated with modest efficacy in previously untreated PTCL patients. | Wei Zhang Liping Su Lihong Liu Yuhuan Gao Quanshun Wang Hang Su Yuhuan Song Huilai Zhang Jing Shen Hongmei Jing Shuye Wang Xinan Cen Hui Liu Aichun Liu Zengjun Li Jianmin Luo Jianxia He Jingwen Wang O.A.O’Connor Daobin Zhou | 2021 | Cancer Biology & Medicine2021，18，3： | 4 |
| 5 | Identification of genes for normalization of quantitative real-time PCR data in ovarian tissues显示文摘增加的注意在最近的年里为卵巢的癌症对潜在的 biomarker 和治疗学的目标的决心被给予了。然而,量的即时 PCR 的正规化是重要的获得精确基因表示数据。我们在不同条件下面在卵巢的纸巾调查了 20 参考基因的稳定性决定为这应用最足够。学习在包含正常、非恶意、主要的卵巢的癌的 52 件卵巢的织物样品之中描绘了 20 可能的参考基因的表示。变化(ANOVA ) 的单程的分析方法被用来比较疾病前进引起的候选人基因变化。没有统计差别的基因的稳定性和适用性是进一步的采用 geNorm 和 NormFinder 软件验证。当尽管有不同卵巢的织物条件, RPL4, RPLP0, HSPCB, TPT1, RPL13A, 18S rRNA, PPIA, TBP,和 GUSB 使稳定性统计时,结果证明 20 参考基因的表示层次变化了。RPL4, RPLP0,和 HSPCB 作为最稳定的参考基因和 RPLP0 的联合被表明, RPL4 应该被推荐为更可靠的正规化策略。 | Jie Fu Lihong Bian Li Zhao Zhouhuan Dong Xin Gao Haofei Luan Yunjuan Sun Haifeng Song | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 4 |
| 6 | Impact effects on fused quartz glass by ground simulating hypervelocity space debris显示文摘The optical attenuation of fused silica glass impacted by high-speed micro-particle was studied.The high-speed impact test was carried out using a laser-driven flyer system which accelerated 16 ?m-thick flyer to high speed of 3.7 km s?1.Scanning electron microscopy and optical microscopy were used to characterize the damage morphology of the impacted surface.The transmittance of the impacted glass samples was measured by means of UV/VIS double beam spectrophotometer.It was found that the transmittance of the impact region decreased due to the formation of structural defects such as crater,ejecta and micro-crack on the surface.A mathematic formula was established to explain the relationship between glass optical properties and the damaged modes,which aids to describe optical degradation and design long life optical equipments used in spacecrafts under space particles environment. | SONG LiHong WEI Qiang BAI Yu GAO Cheng | 2013 | Chinese Science Bulletin2013，58，7： | 4 |
| 7 | Growth–climate response and drought reconstruction from tree-ring of Mongolian pine in Hulunbuir,Northeast China显示文摘Aims Drought affected by atmosphere–ocean cycle is a dominant factor influencing tree radial growth of sandy Mongolian pine(Pinus sylvestris var.mongolica)and regional vegetation dynamics in Hulunbuir,China.However,historical droughts and its correlations with tree radial growth and atmosphere–ocean cycle in this area have been little tested.Methods We developed tree-ring chronologies of Mongolian pine from Hulunbuir,Inner Mongolia,China and analyzed the correlations between tree-ring width index,the normalized difference vegetation index and Palmer drought severity index(PDSI),then developed a linear model to reconstruct the drought variability from 1829 to 2009.Long-term trends and its linkages with atmosphere–ocean cycle were performed by the power spectral,wavelet and teleconnection analysis.Important Findings The local moisture variations affected largely the regional vegetation dynamics and tree-ring growth of Mongolia pine in the forest–grassland transition.Using tree-ring width chronology of Mongolian pine,the reconstruction explains 49.2%of PDSI variance during their common data period(1951–2005).The reconstruction gives a broad-scale regional representation of PDSI in the Hulunbuir area,with drought occurrences in the 1850s,1900s,1920s,mid-1930s and at the turn of the 21st century.Comparisons with other treering drought reconstructions and historical records reveal some common drought periods and drying trends in recent decades at the northern margin zones of the East Asian summer monsoon(EASM).The drying trends in these zones occurred earlier than weakening of the EASM.A REDFIT spectral analysis shows significant peaks at 7.2,3.9,2.7–2.8,2.4 and 2.2 years with a 0.05 significance level,and 36.9,18.1 and 5.0 years with 0.1 significance level.Wavelet analysis also shows similar cycles.Drought variations in the study area significantly correlated with sea surface temperatures in the western tropical Pacific Ocean and middle and northern Indian Ocean,and the Pacific Decadal Oscillation and North Atlantic Oscillation.This suggests a possible linkage with the El Niño-Southern Oscillation,the EASM and the Westerlies. | Zhongjie Shi Lihong Xu Linshui Dong Jixi Gao Xiaohui Yang Shihai Lü Chaoyang Feng Aiyun Song Hao Guo Xiao Zhang | 2016 | Journal of Plant Ecology2016，9，1： | 3 |
| 8 | Structural properties of GaN(0001) epitaxial layers revealed by high resolution X-ray diffraction显示文摘High-resolution X-ray diffraction has been used to analyze GaN(0001) epitaxial layers on sapphire substrates. Several structural properties of GaN, including the lattice constants, strains, and dislocation densities are revealed by the technique of X-ray dffraction (XRD). Lattice constants calculated from the omega/2theta scan are c=0.5185 nm and a=0.3157 nm. Also, the in-plane strain is -1.003%, while out of the plane, the epitaxial film is almost relaxed. Several methods are used to deduce the mosaicity and dislocation density of GaN, showing that the edge type dislocations are the overwhelming majority. | XIE ZiLi 1,2,3, ZHOU YuanJun 1 , SONG LiHong 1,2 , LIU Bin 1 , HUA XueMei 1,2 , Xiu XiangQian 1 , ZHANG Rong 1,2,3 & ZHENG YouDou 1,2,3 1 JiangSu Provincial Key Laboratory of Advanced Photonic and Electronic Materials and Department of Physics, Nanjing University, Nanjing 210093, China 2 Nanjing National Laboratory of Microstructures, Nanjing 210093, China 3 NJU-Yangzhou Institute of Opto-electronics, Yangzhou, 225001, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，1： | 3 |
| 9 | Preparation and Characterization of Tung Oil Toughened Modified Phenolic Foams with Enhanced Mechanical Properties and Smoke Suppression显示文摘In this study,we prepared a series of tung oil phenolic foams(TPF)by a one-pot method.The FT-IR and 1H NMR spectra confirm the successful Friedel-Crafts grafting of phenol to the long-chain alkyl group in tung oil.Modified TPFs exhibit enhanced mechanical properties,including compressive and flexural strengths of up to 0.278±0.036 MPa and 0.450±0.017 MPa,respectively,which represent increases of 68.75%and 86.72%over those of pure phenolic foam(PF).SEM spectra reveal the TPF microstructure to have uniform hexagonal cell morphology,narrower cell size distribution,and smaller mean cell size,suggesting enhanced mechanical properties.The TPF total smoke release decreased by 74.23%,indicating that the long alkyl chain significantly improves smoke suppression of the combusting foam.However,due to the flammability of the alkyl chains,the TPF limiting oxygen index decreases with increasing tung oil content.Moreover,TPF exhibits reduced thermal stability and high-temperature charring rate,elevated peak and mean heat release rates,and higher total heat release compared with pure PF.Therefore,future research will focus on the use of tung oil modified flame retardant to provide more robust phenolic foams. | Fei Song Puyou Jia Caiying Bo Xiaoli Ren Lihong Hu Yonghong Zhou | 2020 | Journal of Renewable Materials2020，8，5： | 2 |
| 10 | Scaled-up synthesis of defect-rich layered double hydroxide monolayers without organic species for efficient oxygen evolution reaction显示文摘The scaled-up synthesis of organic-free monolayer nanomaterials is highly desirable,especially in obtaining green energy by electrocatalysis.In this study,a method for the scaled-up synthesis of the series of monolayer layered double hydroxides(LDHs)without the addition of organic solvents is reported via the separate nucleation and aging steps process.The resulting monolayer LDHs with the thicknesses of less than 1 nm showed a narrow thickness distribution.X-ray absorption fine-structure revealed that monolayer NiFe-LDH nanosheets have a number of oxygen and metal vacancies defects.As a practical application,monolayer NiFe-LDH nanosheets containing defects showed an enhanced electrocatalytic water oxidation activity compared with that of bulk NiFe-LDH.Density functional theory calculations uncovered that excellent catalytic activity is attributed to vacancies defects.The proposed method is an economical and universally applicable strategy for the scaled-up production of monolayer LDHs. | Haoyuan Chi Jingwen Dong Tian Li Sha Bai Ling Tan Jikang Wang Tianyang Shen Guihao Liu Lihong Liu Luyi Sun Yufei Zhao Yu-Fei Song | 2022 | Green Energy & Environment2022，7，5： | 2 |
| 11 | Effects of Root Zone Temperature on Growth and Photosynthetic Parameters of Grafted Cucumber显示文摘Taking Cucurbita maxima and Cucurbita moschata as root stocks,and‘Jinyou No 3'cucumber as scion,the effects of different root zone temperature conditions optimal temperature( CK)( 18-20 ℃),suboptimal temperature( 13-15 ℃) and low temperature( 8-10 ℃) on the growth and photosynthesis indexes were studied. The results showed that,compared with optimal temperature( CK),suboptimal temperature and low temperature produced a significant inhibition of growth on cucumbers. The plant height,stem diameter,leaf area,number of leaves and dry weight of aboveground part were all reduced,dry weight of underground part and root shoot ratio all increased,while the inhibition was more significant at low temperature. Low and suboptimal temperature conditions also reduced SPAD value,net photosynthetic rate,transpiration rate,intercellular CO_2 concentration and stomatal conductance of the grafted cucumber. And there were differences between different grafted seedlings,and seedlings with‘black seeds' as stock performed better than those with‘white seeds' as stock at low temperature. | shijun sun shimao cui yang song chongyi fu lihong ye yu gao | 2018 | Agricultural Biotechnology2018，7，2： | 2 |
| 12 | Ecology of testate amoebae and their potential use as palaeohydrologic indicators from peatland in Sanjiang Plain, Northeast China显示文摘留有遗嘱的阿米巴是在 peatlands 的底层潮湿的敏感指示物。在最后十年,他们被学习了重建自从 Holocene,水文学变化。然而,这些研究地理上被限制了为北美洲和欧洲。我们在最大的大陆人上进行了留有遗嘱的阿米巴的第一调查在 Sanjiang 平原的新鲜的水沼泽地,中国。这研究的目的是在东北中国的 peatlands 在留有遗嘱的阿米巴的生态学上提供基线数据并且估计在这个生态系统把他们用作环境指示物的潜力。我们在 5 浸泡了水的消沉以内在 46 microsites 检验了现代留有遗嘱的变形虫集合和种类环境的关系。测量的环境参数包括了:深度将在点火上浇表格, pH,和损失。结果证明主导的种类是 Trinema complanatum 类型, Euglypha 圆形大厅类型, Euglypha strigosa 类型,和 Centropyxis 产於欧洲的黑醋栗类型。冗余性分析证明水表格深度在留有遗嘱的变形虫集合上有最重要的效果,解释 16.7%(p = 0.002 ) 全部的变化。pH 不是为留有遗嘱的变形虫集合的一个统计上重要的因素。加权的平均和加权的平均部分最少的广场模型被用来造转移功能让深度浇表格。最好表现的转移功能被加权的平均部分最少的广场模型与 r 产生 < 啜 class= “ a-plus-plus ” > 2 < 潜水艇 class= “ a-plus-plus ” > 0.62 的 LOSO 和 RMSEP < 潜水艇 class= “ a-plus-plus ” > 6.96 厘米的 LOSO 。结果显示在浸泡了水的消沉 peatland 的留有遗嘱的阿米巴有潜力在 Sanjiang 平原为水文学变化并且为 palaeohydrologic 重建被用作指示物。 | Lihong SONG Hongkai LI Kehong WANG Donghui WU Haitao WU | 2014 | Frontiers of Earth Science2014，8，4： | 2 |
| 13 | Parallel induction of cell proliferation and inhibition of cell differentiationin hepatic progenitor cells by hepatitis B virus X gene显示文摘 | Jiayi Huang Lihong Shen Yongliang Lu Hongli Li Xifeng Zhang Daixi Hu Tao Feng Fangzhou Song | 2012 | International Journal of Molecular Medicine2012，，4： | 1 |
| 14 | Editing of Rice Endosperm Plastidial Phosphorylase Gene OsPho1 Advances Its Function in Starch Synthesis显示文摘OsPho1 in Zhonghua 11(ZH11)was edited using the clustered regularly interspaced short palindromic repeatsassociated endonuclease 9(CRISPR/Cas9)system.Two homozygous T1 mutants(cr-pho1-34 and cr-pho1-37)displayed a chalky endosperm with a white core,which significantly decreased 1000-grain weight.In addition,many rounded starch granules and abnormal amyloplasts were present in the central region of mutant endosperm cells with increased amylose and lipid contents,decreased total protein content,and altered physicochemical properties of starch.The OsPho1 protein is localized in chloroplasts,and quantitative real-time PCR(qRT-PCR)andβ-glucuronidase(GUS)staining indicated that OsPho1 was highly expressed in seeds at 5 d after fertilization(DAF).OsPho1 mutations displayed close relationships with plastidial phosphoglucomutase and ADPGlc pyrophosphorylase based onα-D-glucose-1P at different temperatures.Moreover,the expressions of starch metabolismrelated genes were also altered in the mutant,and the overexpression of OsPho1 may cause grain chalkiness. | LIU Song SHAO Gaoneng JIAO Guiai ZHU Maodi WU Jiamin CAO Ruijie CHEN Yujuan XIE Lihong SHENG Zhonghua TANG Shaoqing | 2021 | Rice science2021，28，3： | 1 |
| 15 | Crack deflection occurs by constrained microcracking in nacre显示文摘For decades, nacre has inspired researchers because of its sophisticated hierarchical structure and remarkable mechanical properties, especially its extreme fracture toughness compared with that of its predominant constituent,CaCO_3, in the form of aragonite. Crack deflection has been extensively reported and regarded as the principal toughening mechanism for nacre. In this paper, our attention is focused on crack evolution in nacre under a quasi-static state. We use the notched three-point bending test of dehydrated nacre in situ in a scanning electron microscope(SEM) to monitor the evolution of damage mechanisms ahead of the crack tip. The observations show that the crack deflection actually occurs by constrained microcracking. On the basis of our findings, a crack propagation model is proposed, which will contribute to uncovering the underlying mechanisms of nacre's fracture toughness and its damage evolution. These investigations would be of great value to the design and synthesis of novel biomimetic materials. | Jingru Song Cuncai Fan Hansong Ma Lihong Liang Yueguang Wei | 2018 | Acta Mechanica Sinica2018，34，1： | 1 |
| 16 | Knockdown of glucose?regulated protein 78 abrogates chemoresistanceof hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein inresponse to severe hypoxia显示文摘 | Lihong Pi Xiaoming Li Qi Song Yupeng Shen Xiuying Lu Bin Di | 2014 | Oncology Letters2014，，： | 1 |
| 17 | SPECIAL ISSUE: RELIGION AND SOCIETY: CROSS-CULTURAL COMMUNICATION显示文摘 | Song Lihong Lu Yunfeng | 2010 | Social Sciences in China2010，31，1： | 1 |
| 18 | Novel functional variants locus in PLCE1 and susceptibility to esophageal squamous cell carcinoma: Based on published genome-wide association studies in a central Chinese population显示文摘 | Fujiao Duan Wei Xie Lihong Cui Peng Wang Chunhua Song Honghong Qu Kaijuan Wang Jianying Zhang Liping Dai | 2013 | Cancer Epidemiology2013，，： | 1 |
| 19 | Second generation optical re solution photoacoustic microscopy with improved sensitivity and speed显示文摘 | Hu Song Maslov Konstantin Wang Lihong V | | 0，，07： | 1 |
| 20 | Evaluating the mechanical properties of anisotropic shale containing bedding and natural fractures with discrete element modeling显示文摘Natural fracture data from one of the Carboniferous shale masses in the eastern Qaidam Basin were used to establish a stochastic model of a discrete fracture network and to perform discrete element simulation research on the size efect and mechanical parameters of shale.Analytical solutions of fctitious joints in transversely isotropic media were derived,which made it possible for the proposed numerical model to simulate the bedding and natural fractures in shale masses.The results indicate that there are two main factors infuencing the representative elementary volume(REV)size of a shale mass.The frst and most decisive factor is the presence of natural fractures in the block itself.The second is the anisotropy ratio:the greater the anisotropy is,the larger the REV.The bedding angle has little infuence on the REV size,whereas it has a certain infuence on the mechanical parameters of the rock mass.When the bedding angle approaches the average orientation of the natural fractures,the mechanical parameters of the shale blocks decrease greatly.The REV representing the mechanical properties of the Carboniferous shale masses in the eastern Qaidam Basin were comprehensively identifed by considering the infuence of bedding and natural fractures.When the numerical model size is larger than the REV,the fractured rock mass discontinuities can be transformed into equivalent continuities,which provides a method for simulating shale with natural fractures and bedding to analyze the stability of a borehole wall in shale. | Yingjie Li Lihong Song Yuanjun Tang Jianping Zuo Dongjie Xue | 2022 | International Journal of Coal Science & Technology2022，9，2： | 1 |
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