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| 1 | 烧结工艺使用气体燃料喷入技术减少CO_2排放显示文摘JFE钢铁公司开发了在烧结矿表面喷入含氢的气体燃料技术,可不增加焦粉配比,提高烧结矿质量。使用该技术,含氢气体可部分替代焦粉,使1200~1400℃的燃烧层变宽成为可能。通过X射线对多孔状的烧结饼进行CT检查与烧结锅试验,从理论到实践都证明了喷入燃料气体技术的使用效果。保持1200~1400℃的温度带,为生产高强度、高还原性的烧结矿至关重要,它能使合适的温度带变宽、液相率增加、提高1~5mm孔隙间的熔合并提升烧结矿强度。大于5mm的孔隙的烧结矿数量增多提高了料层的透气性,低温烧结工艺也抑制了铁矿石的自身熔化。而在未熔化的铁矿石中,小于1μm的微孔隙的存在也使烧结矿的还原性提高,从而改善烧结饼的孔隙结构,提高烧结矿质量。2009年1月,京浜1号烧结机应用了该技术,到目前为止工况稳定。结果,烧结工序的能源利用率大幅提升,减排CO2约6万t/a。 | Nobuyuki Oyama Yuji Iwami Satoshi Machida Takahide Higuchi Tetsuya Yamamoto Yushinori Watanabe Michitaka Sato Kanji Takeda Masakata Shimizu Koki Nishioka 何海良 | 2013 | 世界钢铁2013，，1： | 11 |
| 2 | DOG1 is useful for diagnosis of KIT-negative gastrointestinal stromal tumor of stomach显示文摘Approximately 80%-95%of gastrointestinal stromal tumors(GISTs)show positive staining for KIT,while the other 5%-20%show negative staining.If the tumor is negative for KIT,but is positive for CD34,a histological diagnosis is possible.However,if the tumor is negative for KIT,CD34,S-100,and SMA,a definitive diagnosis is often challenging.Recently,Discovered on GIST-1(DOG1)has received considerable attention as a useful molecule for the diagnosis of GIST.DOG1,a membrane channel protein,is known to be overexpressed in GIST.Because the sensitivity and specificity of DOG1 are higher than those of KIT,positive staining for DOG1has been reported,even in KIT-negative GISTs.KITnegative GISTs most commonly arise in the stomach and are mainly characterized by epithelioid features histologically.We describe our experience with a rare case of a KIT-negative GIST of the stomach that was diagnosed by positive immunohistochemical staining for DOG1 in a patient who presented with severe anemia.Our findings suggest that immunohistochemical staining for DOG1,in addition to gene analysis,is useful for the diagnosis of KIT-negative tumors that are suspected to be GISTs. | Takuya Wada Satoshi Tanabe Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Akira Naruke Myunguchul Kim Wasaburo Koizumi Tetsuo Mikami | 2013 | World Journal of Gastroenterology2013，19，47： | 11 |
| 3 | 胆道肿瘤临床实践指南(英文第三版)显示文摘日本肝胆胰外科学会(JSHBPS)于2007年出版第一版胆道肿瘤(胆管癌、胆囊癌及壶腹癌)临床实践指南,于2014年更新第二版,2021年英文第三版胆道肿瘤临床实践指南围绕6个主题提出若干临床问题,基于相关循证医学证据并组织专家讨论后,最终确定推荐意见、推荐强度以及推荐说明。根据证据推荐分级的评估、制订与评价(GRADE)系统,推荐强度被分为1级(强)或者2级(弱)。英文第三版胆道肿瘤临床实践指南中提出的31个临床问题涵盖:(1)预防性治疗;(2)诊断;(3)胆道引流;(4)外科治疗;(5)化疗;(6)放疗。31个临床问题中,14个问题给予推荐强度为强的推荐意见,14个问题给予推荐强度为弱的推荐意见,剩余的3个问题未给予推荐意见。每条推荐意见都进行推荐强度说明。最新版指南基于循证医学证据,为临床提供了重要建议。未来与癌症登记数据库协作将是评估指南和建立新证据的关键。 | Masato Nagino Satoshi Hirano Hideyuki Yoshitomi Taku Aoki Katsuhiko Uesaka Michiaki Unno Tomoki Ebata Masaru Konishi Keiji Sano Kazuaki Shimada Hiroaki Shimizu Ryota Higuchi Toshifumi Wakai Hiroyuki Isayama Takuji Okusaka Toshio Tsuyuguchi Yoshiki Hirooka Junji Furuse Hiroyuki Maguchi Kojiro Suzuki Hideya Yamazaki Hiroshi Kijima Akio Yanagisawa Masahiro Yoshida Yukihiro Yokoyama Takashi Mizuno Itaru Endo 杨翼飞(译) 仇毓东(译) 赵梦珂(译) 伏旭(译) 蔡正华(译) 毛凉(审校) | 2021 | 中华消化外科杂志2021，20，4： | 7 |
| 4 | Argon plasma coagulation for superficial esophageal squamous-cell carcinoma in high-risk patients显示文摘AIM: To evaluate the usefulness and safety of argon plasma coagulation (APC) for superficial esophageal squamous-cell carcinoma (SESC) in high-risk patients. METHODS: We studied 17 patients (15 men and 2 women, 21 lesions) with SESC in whom endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and open surgery were contraindicated from March 1999 through February 2009. None of the patients could tolerate prolonged EMR/ESD or open surgery because of severe concomitant disease (e.g., liver cirrhosis, cerebral infarction, or ischemic heart disease) or scar formation after EMR/ESD and chemoradiotherapy. After conventional endoscopy, an iodine stain was sprayed on the esophageal mucosa to determine the lesion margins. The lesion was then ablated by APC. We retrospectively studied the treatment time, number of APC sessions per site, complications, presence or absence of recurrence, and time to recurrence.RESULTS: The median duration of follow-up was 36 mo (range: 6-120 mo). All of the tumors were macroscopically classified as superficial and slightly depressed type (0-Ⅱc). The preoperative depth of invasion was clinical T1a (mucosal cancer) for 19 lesions and clinical T1b (submucosal cancer) for 2. The median treatment time was 15 min (range: 10-36 min). The median number of treatment sessions per site was 2 (range: 1-4). The median hospital stay was 14 d (range: 5-68 d). Among the 17 patients (21 lesions), 2 (9.5%) had recurrence and underwent additional APC with no subsequent evidence of recurrence. There were no treatment-related complications, such as bleeding or perforation. CONCLUSION: APC is considered to be safe and effective for the management of SESC that cannot be resected endoscopically because of underlying disease, as well as for the control of recurrence after EMR and local recurrence after chemoradiotherapy. | Kumiko Tahara Satoshi Tanabe Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Kento Nakatani Akira Naruke Myungchul Kim Wasaburo Koizumi | 2012 | World Journal of Gastroenterology2012，18，38： | 4 |
| 5 | Double-endoscope endoscopic submucosal dissection for the treatment of early gastric cancer accompanied by an ulcer scar (with video)显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Tohru Sasaki Chikatoshi Katada Kenji Ishido Akira Naruke Tetuo Mikami Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，2： | 3 |
| 6 | Small Bowel Injury by Low-Dose Enteric-Coated Aspirin and Treatment With Misoprostol: A Pilot Study显示文摘 | Toshio Watanabe Satoshi Sugimori Natsuhiko Kameda Hirohisa Machida Hirotoshi Okazaki Tetsuya Tanigawa Kenji Watanabe Kazunari Tominaga Yasuhiro Fujiwara Nobuhide Oshitani Kazuhide Higuchi Tetsuo Arakawa | 2008 | Clinical Gastroenterology and Hepatology2008，，11： | 2 |
| 7 | Optimization of coke breeze sega'egation in sintering bed under high pisolite ore ratio 显示文摘 | MACHIDA Satoshi HIGUCHI Takahide OYAMA Nobuyuki | 2009 | ISIJ International2009，49，5： | 1 |
| 8 | Opti- mization of coke breeze segregation in sintering bed under high piso-lite ore ratio 显示文摘 | Maehida Satoshi Higuchi Takahide Oyama Nobuyuki et al | 2009 | ISIJ International2009，49，5： | 1 |
| 9 | Present status and strategy of NSAIDs-induced small bowel injury显示文摘 | Kazuhide Higuchi Eiji Umegaki Toshio Watanabe Yukiko Yoda Eijiro Morita Mitsuyuki Murano Satoshi Tokioka Tetsuo Arakawa | 2009 | Journal of Gastroenterology2009，，9： | 1 |
| 10 | A novel endoscopic submucosal dissection technique for proton pump inhibitor-refractory gastroesophageal reflux disease显示文摘 | Kazuhiro Ota Toshihisa Takeuchi Satoshi Harada Shoko Edogawa Yuichi Kojima Takuya Inoue Kazuhide Higuchi | 2014 | Scandinavian Journal of Gastroenterology2014，，12： | 1 |
| 11 | β‐amyloid in lewy body disease is related to Alzheimer’s disease‐like atrophy显示文摘 | Hitoshi Shimada Hitoshi Shinotoh Shigeki Hirano Michie Miyoshi Koichi Sato Noriko Tanaka Tsuneyoshi Ota Kiyoshi Fukushi Toshiaki Irie Hiroshi Ito Makoto Higuchi Satoshi Kuwabara Tetsuya Suhara | 2012 | Mov Disord2012，，： | 1 |
| 12 | Double-endoscope endoscopic submucosal dissection for the treatment of early gastric cancer accompanied by an ulcer scar (with video)显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Tohru Sasaki Chikatoshi Katada Kenji Ishido Akira Naruke Tetuo Mikami Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，2： | 1 |
| 13 | A patient with undifferentiated carcinoma of gallbladder presenting with hemobilia显示文摘 | Hiroyuki Kubota Masanobu Kageoka Hirohiko Iwasaki Ken Sugimoto Ryota Higuchi Satoshi Honda Fumitoshi Watanabe Kenji Koda Hiroyuki Hanai Eizo Kaneko | 2000 | Journal of Gastroenterology2000，，1： | 1 |
| 14 | Prognostic Impact of Hypoxia-Inducible miRNA-210 in Patients with Lung Adenocarcinoma显示文摘 | Jun Osugi Yuka Kimura Yuki Owada Takuya Inoue Yuzuru Watanabe Takumi Yamaura Mitsuro Fukuhara Satoshi Muto Naoyuki Okabe Yuki Matsumura Takeo Hasegawa Athushi Yonechi Mika Hoshino Mitsunori Higuchi Yutaka Shio Hiroyuki Suzuki Mitsukazu Gotoh James L. Muls | 2015 | Journal of Oncology2015，，： | 1 |
| 15 | Effect of High-phosphorous Iron Ore Distribution in Quasiparticle on Melt Fluidity and Sinter Bed Permeability during Sintering 显示文摘 | Nobuyuki OYAMA Takahide HIGUCHI Satoshi MACHIDA | 2009 | ISLI International2009，49，5： | 1 |
| 16 | Long-term outcomes of endoscopic submucosal dissection for early gastric cancer: a retrospective comparison with conventional endoscopic resection in a single center显示文摘 | Satoshi Tanabe Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Akira Naruke Myungchul Kim Wasaburo Koizumi | 2014 | Gastric Cancer2014，，1： | 1 |
| 17 | Discrimination of brain abscess from necrotic or cystic tumors by diffusion-weighted echo planar imaging显示文摘 | Toshihiko Ebisu Chuzo Tanaka Masahiro Umeda Makoto Kitamura Shoji Naruse Toshihiro Higuchi Satoshi Ueda Hiroshi Sato | 1996 | Magnetic Resonance Imaging1996，，9： | 1 |
| 18 | Definitive Chemoradiation Therapy With Docetaxel, Cisplatin, and 5-Fluorouracil (DCF-R) in Advanced Esophageal Cancer: A Phase 2 Trial (KDOG 0501-P2)显示文摘 | Katsuhiko Higuchi Shouko Komori Satoshi Tanabe Chikatoshi Katada Mizutomo Azuma Hiromichi Ishiyama Tohru Sasaki Kenji Ishido Natsuya Katada Kazushige Hayakawa Wasaburo Koizumi | 2014 | International Journal of Radiation Oncology Biology Physics2014，，： | 1 |
| 19 | Clinicopathological evaluation of duodenal well-differentiated endocrine tumors显示文摘AIM:To assess the clinicopathological characteristics of duodenal well-differentiated endocrine tumors.METHODS:We examined clinicopathological characteristics in 11 consecutive patients with duodenal well-differentiated endocrine tumors treated by endoscopic therapy or surgery in our hospital from 1992 through 2007.Patients with well-differentiated endocrine tu-mors of the papilla of Vater or with gastrinoma were excluded.RESULTS:Three patients received endoscopic treatment,and 8 underwent surgery.In patients who received endoscopic treatment,the tumor diameter was less than 1.0 cm,with no histopathological evidence of lymphovascular invasion or invasion of the muscularis.There were no complications such as late bleedingor perforation after treatment.Among 8 patients with tumors less than 1.0 cm in diameter,3 underwent partial resection,and 2 underwent radical surgery.Three patients had lymphovascular invasion,1 had invasion of the muscularis,and 1 had proximal lymph node metastasis.Among 3 patients with tumors 1.0 cm or more in diameter,1 underwent partial resection,and 2 under-went radical surgery.One patient had lymphovascular invasion,with no lymph node metastasis.After treatment,all patients are alive and have remained free of metastasis and recurrence.CONCLUSION:Duodenal well-differentiated endocrine tumors less than 1.0 cm in diameter have a risk of lym-phovascular invasion,invasion of the muscularis,and lymph node metastasis,irrespective of procedural prob-lems. | Kenji Ishido Satoshi Tanabe Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Akira Naruke Wasaburo Koizumi Tetsuo Mikami | 2010 | World Journal of Gastroenterology2010，16，36： | 1 |
| 20 | A phase II study of endoscopic submucosal dissection for superficial esophageal neoplasms (KDOG 0901)显示文摘 | Katsuhiko Higuchi Satoshi Tanabe Mizutomo Azuma Chikatoshi Katada Tohru Sasaki Kenji Ishido Akira Naruke Natsuya Katada Wasaburo Koizumi | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
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