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| 1 | Clinical outcome of Fitz-Hugh-Curtis syndrome mimicking acute biliary disease显示文摘AIM: To analyze the clinical characteristics of patients diagnosed with Fitz-Hugh-Curtis syndrome.METHODS: The clinical courses of patients that visited St. Mary's Hospital with abdominal pain from January 2005 to December 2006 and were diagnosed with Fitz-Hugh-Curtis syndrome were examined.RESULTS: Fitz-Hugh-Curtis syndrome was identified in 22 female patients of childbearing age; their mean age was 31.0 ± 8.1 years. Fourteen of these cases presented with pain in the upper right abdomen alone or together with pain in the lower abdomen, and six patients presented with pain only in the lower abdomen. The first impression at the time of visit was acute cholecystitis or cholangitis in 10 patients and acute appendicitis or pelvic inflammatory disease in eight patients. Twenty-one patients were diagnosed by abdominal computer tomograghy (CT), and the results of abdominal sonography were normal for 10 of these patients. Chlamydia trichomatis was isolated from 18 patients. Two patients underwent laparoscopic adhesiotomy and 20 patients were completely cured by antibiotic treatment.CONCLUSION: For women of childbearing age with acute pain in the upper right abdomen alone or together with pain in the lower abdomen, Fitz-Hugh-Curtis syndrome should be considered during differential diagnosis. Moreover, in cases suspected to be Fitz-Hugh-Curtis syndrome, abdominal CT, rather than abdominal sonography, assists in the diagnosis. | Seong Yong Woo Jin Il Kim Dae Young Cheung Se Hyun Cho Soo-Heon Park Joon-Yeol Han Jae Kwang Kim | 2008 | World Journal of Gastroenterology2008，14，45： | 5 |
| 2 | Monolayer Graphitic Carbon Nitride as Metal-Free Catalyst with Enhanced Performance in Photo- and Electro-Catalysis显示文摘The exfoliation of bulk graphitic carbon nitride(g-C_(3)N_(4))into monolayer has been intensively studied to induce maximum sur-face area for fundamental studies,but ended in failure to realize chemi-cally and physically well-defined monolayer of g-C_(3)N_(4)mostly due to the difficulty in reducing the layer thickness down to an atomic level.It has,therefore,remained as a challenging issue in two-dimensional(2D)chemistry and physics communities.In this study,an“atomic monolayer of g-C_(3)N_(4)with perfect two-dimensional limit”was successfully prepared by the chemically well-defined two-step routes.The atomically resolved monolayer of g-C_(3)N_(4)was also confirmed by spectroscopic and micro-scopic analyses.In addition,the experimental Cs-HRTEM image was collected,for the first time,which was in excellent agreement with the theoretically simulated;the evidence of monolayer of g-C_(3)N_(4)in the perfect 2D limit becomes now clear from the HRTEM image of orderly hexagonal symmetry with a cavity formed by encirclement of three adjacent heptazine units.Compared to bulk g-C_(3)N_(4),the present g-C_(3)N_(4)monolayer showed significantly higher photocatalytic gen-eration of H2O2 and H2,and electrocatalytic oxygen reduction reaction.In addition,its photocatalytic efficiency for H2O2 production was found to be the best for any known g-C_(3)N_(4)nanomaterials,underscoring the remarkable advantage of monolayer formation in optimizing the catalyst performance of g-C_(3)N_(4). | Huiyan Piao Goeun Choi Xiaoyan Jin Seong‑Ju Hwang Young Jae Song Sung‑Pyo Cho Jin‑Ho Choy | 2022 | Nano-Micro Letters2022，14，3： | 3 |
| 3 | Analysis on sports and recreation activity-related eye injuries presenting to the Emergency Department显示文摘AIM:To investigate the incidence and general characteristics of sports-related eye injuries in patients visiting the Emergency Department. METHODS: A cross-sectional,multi-center,observational study.Patients with an injured eye who visited the Emergency Department at one of nine hospitals in Korea were enrolled.All data were prospectively collected between March and September 2010 using a questionnaire.Eye injuries that occurred during risky sports were examined by gender and age.Additionally,the rate of open globe injuries that occurred with and without protective eyewear was examined for each activity.Continuous variables were compared using Student's t-test and categorical variables were compared using Chi-square test.RESULTS: A total of 446 patients had sports-related eye injuries.Teenagers(10-19 years old) and young adults(20-29 years old) had the most eye injuries.Eye injuries accounted for 0.2% of Emergency Department patients.Baseball was the most common cause of sports-related eye injuries,followed by soccer and hiking.Protective gear was worn by 9.4% of all patients.Patients that were 30-39 years of age had the highest rate of protective gear use,followed by patients that were 40-49 years of age.The proportion of sports-related eye injuries that were open-globe injuries was highest for soccer and hiking.CONCLUSION: Although injuries were most common in patients below the age of 10 years,these patients had the lowest rate of protective eyewear use.Injuries in adults over 40 years of age most commonly occurred during hiking,but the rate of protective eyewear use was low.Young athletes should be educated on and provided with protective eyewear and policies protective gear use should be established.For older adults,eye protection should be encouraged,especially during hiking. | Sungbae Moon Hyun Wook Ryoo Jae Yun Ahn Jung Bae Park Kang Suk Seo Sang Do Shin Kyoung Jun Song Kang Hyun Lee In Sool Yoo Jin Seong Cho Hyun Ho Ryu Tae Oh Jeong Seok Ran Yeom Young Taek Kim Sung Ok Hong | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 3 |
| 4 | Suppression of laser-induced choroidal neovascularization by intravitreal injection of tristetraprolin显示文摘AIM: To examine the effect of intravitreal adenoviral vector-mediated tristetraprolin(Ad-TTP) on VEGF m RNA expression in a rat model of laser-induced choroidal neovascularization.METHODS: Ad-TTP was prepared using a commercial kit. Retinal laser-induced photocoagulation(10 spots per eye) was performed on rats in this experimental choroidal neovascularization(CNV) model. Rats were divided into four groups: control(single intravitreal injection of balanced salt solution, n =10), laser-induced CNV(photocoagulation only, n =20), laser-induced CNV plus Ad-TTP injection(photocoagulation plus a single intravitreal Ad-TTP injection, n =20) and Ad-TTP injection only(n =10). Changes in choroidal morphology were evaluated in ten rats in the laser only and the laser plus Ad-TTP groups. Two weeks after laser injury, the size of CNV was calculated by perfusion with high-molecular-weight fluorescein isothiocyanate(FITC)-dextran. VEGF m RNA expression in retina-choroid tissue from ten rats in each group was measured by reverse transcription polymerase chain reaction(RT-PCR). RESULTS: Two weeks after treatment, the area of laser-induced CNV was reduced by approximately 60% in the rats given the Ad-TTP injection compared with that in the laser-only group. There was a tendency toward decreased VEGF m RNA expression in the Ad-TTP injection groups.CONCLUSION: A single intravitreal injection of Ad-TTP significantly suppressed CNV size in this experimental laser-induced CNV model. Ad-TTP injection also decreased VEGF m RNA expression compared with that inthe laser-induced CNV group. The present study is meaningful as the first study to investigate the effect of tristetraprolin delivered via intravitreal injection. | Yong Wun Cho Yong Seop Han In Young Chung Seong Jae Kim Seong Wook Seo Ji Myong Yoo Jong Moon Park | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 2 |
| 5 | A case of intussuscepted Meckel’s diverticulum显示文摘We report colonoscopic features of an intussuscepted Meckel's diverticulum, presenting with hematochezia. A 35-year-old woman presented to the emergency room with acute onset, transient, sharp, severe epi-gastric pain that began 6 h earlier. Colonoscopy re-vealed a reddish, soft, fi st-sized polypoid lesion in the terminal ileum. The lesion was misinterpreted as a hematoma by an inexperienced endoscopist. The pa-tient began to complain of intermittent, severe peri-umbilical pain following the colonoscopic examination. Subsequent computed tomography showed an enteric intussusception. An exploratory laparotomy revealed an intussuscepted Meckel's diverticulum, with trans-mural infarction. Colonoscopy was of little use in as-sessing the intussusception. However, colonoscopic examination may be performed initially, especially in an intussuscepted Meckel's diverticulum present-ing with hematochezia. Endoscopists should note the endoscopic features of an intussuscepted Meckel's diverticulum. | Tae Hee Lee Jin-Oh Kim Jae Joon Kim Seong Sook Hong So Young Jin Hyun Gun Kim Joo Young Cho Joon Seong Lee | 2009 | World Journal of Gastroenterology2009，15，40： | 2 |
| 6 | Impact of patient education with cartoon visual aids on the quality of bowel preparation for colonoscopy显示文摘 | Jae Woong Tae Jong Chan Lee Su Jin Hong Jae Pil Han Yun Hee Lee Jong Ho Chung Hyung Geun Yoon Bong Min Ko Joo Young Cho Joon Seong Lee Moon Sung Lee | 2012 | Gastrointestinal Endoscopy2012，，4： | 2 |
| 7 | Resveratrol prevents hypoxia-induced retinal ganglion cell death related with ErbB2显示文摘AIM: To confirm the changes in proteins related with hypoxia-induced retinal cell death and to assess the effects of resveratrol(Res).METHODS: The therapeutic effect of Res was verified using an ischemic/reperfusion(I/R) model in vivo and a hypoxia modelin retinal ganglion cells(RGCs) in vitro.Death of RGCs were confirmed by TUNEL assay.Protein expression was confirmed by Western blotting and immunohistochemistry.In addition, flow cytometric analysis was used to confirm the response in the cell unit to obtain more accurate data.RESULTS: ErbB2 expression and apoptosis in the ganglion cell layer(GCL) increased after I/R injury.Treatment of Res rescued I/R-induced ganglion cell death, downregulated apoptosis and ErbB2 protein expression in the retina.In subsequent in vitro models, Res affects apoptosis by regulating the phosphorylation and expression of mouse double minute 2 homolog(MDM2), along with those of ErbB2.These results suggest that Res reverses GCL-specific apoptosis via downregulation of ErbB2 in ischemic injury.CONCLUSION: In light of Res favorable properties, it should be evaluated in the treatment of RGC death and related retinal disease characterized by ErbB2 and MDM2 expression.Therefore, Res is appropriate therapeutic agent for treating ischemic injury-related eye diseases by targeting the expression of ErbB2 and MDM2. | Hyemin Seong Joo Yeon Jeong Jinhyun Ryu Juyeong Park Yong‑Seop Han Hyun-Kyung Cho Seong Jae Kim Jong Moon Park Sang Soo Kang Seong Wook Seo | 2022 | International Journal of Ophthalmology(English edition)2022，15，3： | 2 |
| 8 | Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment显示文摘 | Jae‐Hyun Park Sang Won Seo Changsoo Kim Geon Ha Kim Hyun Jin Noh Sung Tae Kim Ki‐Chang Kwak Uicheul Yoon Jong Min Lee Jong Weon Lee Ji Soo Shin Chi Hun Kim Young Noh Hanna Cho Hee Jin Kim Cindy W. Yoon Seung Jun Oh Jae Seung Kim Yearn Seong Choe Kyung‐Han | 2013 | Ann Neurol2013，，5： | 1 |
| 9 | Biological control of Phytophthora blight in red pepper (Capsicum annuum L.) using Bacillus subtilis显示文摘 | Kui Jae Lee Seralathan Kamala-Kannan Han Sang Sub Cho Kyu Seong Gun Woong Lee | 2008 | World Journal of Microbiology and Biotechnology2008，，7： | 1 |
| 10 | Endoscopic resection yields reliable outcomes for small rectal neuroendocrine tumors显示文摘 | Joon Han Jeon Dae Young Cheung Seong Jin Lee Hyun Jin Kim Hye Kang Kim Hyung Jun Cho In Kyu Lee Jin Il Kim Soo‐Heon Park Jae Kwang Kim | 2014 | Digestive Endoscopy2014，，4： | 1 |
| 11 | Inactivating mutations of caspase-8 gene in colorectal carcinomas显示文摘 | Hong Sug Kim Jong Woo Lee Young Hwa Soung Won Sang Park Su Young Kim Jong Heun Lee Jik Young Park Youg Gu Cho Chang Jae Kim Seong Whan Jeong Suk Woo Nam Sang Ho Kim Jung Young Lee Nam Jin Yoo Sug Hyung Lee | 2003 | Gastroenterology2003，，3： | 1 |
| 12 | Effectiveness of stent placement for palliative treatment in malignant colorectal obstruction and predictive factors for stent occlusion显示文摘 | Jung Pil Suh Sang Woo Kim Yu Kyung Cho Jae Myung Park In Seok Lee Myung-Gyu Choi In-Sik Chung Hyung Jin Kim Won Kyung Kang Seong Taek Oh | 2010 | Surgical Endoscopy2010，，2： | 1 |
| 13 | Relationship between coronary artery plaque composition by virtual histology intravascular ultrasound analysis and brachial-ankle pulse wave velocity in patients with coronary artery disease显示文摘 | Jee Eun Kwon Gary S. Mintz Sang-Wook Kim Min Seok Oh Yun Ju Min Hyang Kyoung Kim Jae Seung Seo Wang Soo Lee Kwang Je Lee Tae Ho Kim Chee Jeong Kim Dai Yun Cho Wang Seong Ryu | 2011 | Coronary Artery Disease2011，，8： | 1 |
| 14 | Single-port transumbilical laparoscopic appendectomy: 43 consecutive cases显示文摘 | Hyung Jin Kim Jae Im Lee Yoon Suk Lee In Kyu Lee Jung Hyun Park Sang Kuon Lee Won Kyung Kang Hyeon-Min Cho Young Kyuong You Seong Taek Oh | 2010 | Surgical Endoscopy2010，，11： | 1 |
| 15 | Enhanced IL-18 expression in common skin tumors显示文摘 | Hyunjeong Park Daegyoo Byun Tae S. Kim Young I. Kim Jae S. Kang Eun S. Hahm Seong H. Kim Wang J. Lee Hyun K. Song Do Y. Yoon Chang J. Kang Changnam Lee Dong Houh Hyungok Kim Baikkee Cho Youngsill Kim Yool H. Yang Kyung H. Min Dae H. Cho | 2001 | Immunology Letters2001，，3： | 1 |
| 16 | Chraracteristics of Crack Growth of Alumina Ceramics Under Cyclic Loadslnternational 显示文摘 | Yong Hak Huh Seong Jae Cho Jiho Song | 2003 | Journal of Modern Physics B2003，17，89： | 1 |
| 17 | Estimated prevalence and trends in smoking among adolescents in South Korea,2005-2021:a nationwide serial study显示文摘Background Although smoking is classified as a risk factor for severe COVID-19 outcomes,there is a scarcity of studies on prevalence of smoking during the COVID-19 pandemic.Thus,this study aims to analyze the trends of prevalence of smoking in adolescents over the COVID-19 pandemic period.Methods The present study used data from middle to high school adolescents between 2005 and 2021 who participated in the Korea Youth Risk Behavior Web-based Survey(KYRBS).We evaluated the smoking prevalence(ever or daily)by year groups and estimated the slope in smoking prevalence before and during the pandemic.Results A total of 1,137,823 adolescents participated in the study[mean age,15.04 years[95%confidence interval(CI)15.03-15.06];and male,52.4%(95%CI 51.7-53.1)].The prevalence of ever smokers was 27.7%(95%CI 27.3-28.1)between 2005 and 2008 but decreased to 9.8%(95%CI 9.3-10.3)in 2021.A consistent trend was found in daily smokers,as the estimates decreased from 5.4%(95%CI 5.2-5.6)between 2005 and 2008 to 2.3%(95%CI 2.1-2.5)in 2021.However,the downward slope in the overall prevalence of ever smokers and daily smokers became less pronounced in the COVID-19 pandemic period than in the pre-pandemic period.In the subgroup with substance use,the decreasing slope in daily smokers was significantly more pronounced during the pandemic than during the pre-pandemic period.Conclusions The proportion of ever smokers and daily smokers showed a less pronounced decreasing trend during the pandemic.The findings of our study provide an overall understanding of the pandemic's impact on smoking prevalence in adolescents. | Hyoin Shin Sangil Park Hyunju Yon Chae Yeon Ban Stephen Turner Seong Ho Cho Youn Ho Shin Jung U.Shin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min Young Joo Lee So Young Kim Jinseok Lee Rosie Kwon Min Ji Koo Guillaume Fond Laurent Boyer Jong Woo Hahn Namwoo Kim Sang Youl Rhee Jae Il Shin Ho Geol Woo Hyeowon Park Hyeon Jin Kim Yoonsung Lee Man S.Kim Eléa Lefkir Vlasta Hadalin Jungwoo Choi Seung Won Lee Dong Keon Yon Sunyoung Kim | 2023 | World Journal of Pediatrics2023，19，4： | 1 |
| 18 | Usefulness of magnifying endoscopy for iodine-unstained lesions in a high-risk esophageal cancer population显示文摘AIM: To investigate the usefulness of magnified observations of iodine-unstained esophageal lesions in the histological diagnosis of esophageal mucosa abnormalities, in high-risk esophageal cancer groups. METHODS: The subjects included 38 patients who had at least one of the four criteria known to be highrisk factors for esophageal cancer. Following endoscopic observation, magnified observations were performed on iodine-unstained lesions of the esophagus. The total number of lesions was 43. These lesions were classified as type A (clear papilla), type B (fused papilla), and type C (non-visible papilla) according to the findings. Tissue biopsy was then carried out. Finally the histological findings were graded in terms of histological factors, and their relationships were compared. RESULTS: Of the 43 lesions, 11 were type A, 17 were type B, and 15 were type C under magnifying endoscopy. Histological findings such as inflammatory cell infiltration and basal cell hyperplasia were significantly increased in type B and type C lesions compared with type A lesions (P < 0.05). Low-grade esophageal dysplasia was apparent in 1 (9%) of 11 type A lesions, in 3 (18%) of 17 type B lesions, and in 6 (40%) of 15 type C lesions, with the highest rate in type C. CONCLUSION: Magnified observations of the esophagus, classified by papillary aspects using magnifying endoscopy of iodine-unstained lesions in high-risk esophageal cancer groups, are considered useful in estimating dysplasia and inflammation of esophageal mucosa. | Ik Seong Choi Jae Young Jang Won Young Cho Tae Hee Lee Hyun Gun Kim Bo Young Lee Soung Won Jeong Joo Young Cho Joon Seong Lee So Young Jin | 2010 | World Journal of Gastroenterology2010，16，37： | 1 |
| 19 | Incidental focal colorectal ^(18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography显示文摘AIM: To assess the clinical significance of incidental focal colorectal 18 F-fluorodeoxyglucose ( 18 F-FDG) uptake on 18 F-FDG-positron emission tomography/computed tomography (PET/CT). METHODS: The records of all the cases which had undergone colonoscopy after PET/CT within a two weeks interval were reviewed. Adenomas were considered advanced when they were villous, ≥ 10 mm in size, or had high-grade dysplasia. Colorectal cancers and advanced adenomas are collectively referred to as advanced colorectal neoplasms. Receiver-operating characteristic curve analysis was used to determine thesignificant predictive maximum standardized uptake value (SUVmax) cutoff value for advanced colorectal neoplasms and cancer. RESULTS: Ninety-five colorectal lesions matched the site of incidental focal colorectal 18 F-FDG uptake on PET/CT and 146 did not. Colonoscopy showed advanced colorectal neoplasms corresponding to the site of 18 F-FDG uptake in 49 of the 95 (51.5%) lesions with incidental uptake. Of the lesions without incidental uptake, only 6 of 146 (4.1%) had advanced colorectal neoplasms on colonoscopy, indicating a statistically significant difference between the two groups (P < 0.001). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of incidental focal 18 F-FDG uptake in identifying advanced colorectal neoplasms were 89.1%, 75.3%, 51.6%, 95.9%, and 78.4%, respectively. In detecting only CRC, these values were 89.2%, 69.6%, 34.7%, 97.3%, and 72.6%, respectively. The significant SUVmax cutoff value for advanced colorectal neoplasms (area under the curve 0.755, P < 0.001) was 4.35, with a sensitivity, specificity, PPV, NPV, and accuracy of 75.5%, 65.2%, 69.8%, 71.4% and 70.5%, respectively. For CRC, 5.05 was the significant SUVmax cutoff value (area under the curve 0.817, P < 0.001), with a sensitivity, specificity, PPV, NPV, and accuracy of 84.8%, 71.0%, 80.9%, 89.8%, and 75.8%, respectively. CONCLUSION: The presence of incidental focal colorectal 18 F-FDG uptake on PET/CT with a SUVmax ≥ 4.35 increases the likelihood of an advanced colorectal neoplasm. | Soung Hoon Cho Sang Woo Kim Won Chul Kim Jae Myung Park Ie Ryung Yoo Sung Hoon Kim Seong Taek Oh | 2013 | World Journal of Gastroenterology2013，19，22： | 1 |
| 20 | Single-port transumbilical laparoscopic appendectomy: 43 consecutive cases显示文摘 | Hyung Jin Kim Jae Im Lee Yoon Suk Lee In Kyu Lee Jung Hyun Park Sang Kuon Lee Won Kyung Kang Hyeon-Min Cho Young Kyuong You Seong Taek Oh | 2010 | Surgical Endoscopy2010，，11： | 1 |
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