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| 1 | Comparison of hepatic venous pressure gradient and endoscopic grading of esophageal varices显示文摘AIM: To determine the correlation between the hepatic venous pressure gradient and the endoscopic grade of esophageal varices.METHODS: From September 2009 to March 2013, a total of 176 measurements of hepatic venous pressure gradient(HVPG) were done in 146 patients. Each transjugular HVPG was measured twice, first using an end whole catheter(EH-HVPG), and then using a balloon catheter(B-HVPG). The HVPG was compared with the endoscopic grade of esophageal varices(according to the general rules for recording endoscopic findings of esophagogastric varices), which was recorded within a month of the measurement of HVPG.RESULTS: The study included 110 men and 36 women, with a mean age of 56.1 years(range, 43-76 years). The technical success rate of the pressure measurements was 100% and there were no complication related to the procedures. Mean HVPG was 15.3 mm Hg as measured using the end hole catheter method and 16.5 mm Hg as measured using the balloon catheter method. Mean HVPG(both EHHVPG and B-HVPG) was not significantly different among patients with different characteristics, including sex and comorbid factors, except for cases with hepatocellular carcinoma(B-HVPG, P = 0.01; EH-HVPG, P = 0.02). Portal hypertension(> 12 mm Hg HVPG) occurred in 66% of patients according to EH-HVPG and 83% of patients according to B-HVGP, and significantly correlated with Child's status(B-HVPG, P < 0.000; EHHVGP, P < 0.000) and esophageal varies observed upon endoscopy(EH-HVGP, P = 0.003; B-HVGP, P = 0.006). One hundred and thirty-five endoscopies were performed, of which 15 showed normal findings, 27 showed grade 1 endoscopic esophageal varices, 49 showed grade 2 varices, and 44 showed grade 3 varices. When comparing endoscopic esophageal variceal grades and HVPG using univariate analysis, the P value was 0.004 for EH-HVPG and 0.002 for B-HVPG. CONCLUSION: Both EH-HVPG and B-HVPG showed a positive correlation with the endoscopic grade of esophageal varices, with B-HVPG showing a stronger correlation than EH-HVPG. | Eun Ji Lee Yong Jae Kim Dong Erk Goo Seung Boo Yang Hyun-Joo Kim Jae Young Jang Soung Won Jeong | 2016 | World Journal of Gastroenterology2016，22，11： | 11 |
| 2 | Poly-gamma-glutamic acid from Bacillus subtilis upregulates pro-inflammatory cytokines while inhibiting NLRP3, NLRC4 and AIM2 inflammasome activation显示文摘Poly-gamma-glutamic acid(γ-PGA)is a natural,edible and non-toxic polymer synthesized by Bacillus subtilis and is suggested as a safe biomaterial for the use in hydrogels and vaccine adjuvants.However,the effect ofγ-PGA on inflammasome activation has not yet been studied in macrophages.Inflammasomes,which are intracellular multi-protein complexes,promote acute and chronic inflammation via interleukin-1βor interleukin-18 maturation,and they are known targets for metabolic syndromes and cancer.In this study,we observed thatγ-PGA attenuated NLRP3,NLRC4 and AIM2 inflammasome activation,whereas it upregulated pro-inflammatory cytokine expression in human and murine macrophages.Althoughγ-PGA had conflicting effects on cytokine production and maturation,it clearly alleviated the severity of lipopolysaccharide-induced endotoxin shock in an animal model.Thus,we suggestγ-PGA as a candidate to control inflammasome-mediated disorders. | Huijeong Ahn Seung Goo Kang Sung-il Yoon Pyeung-Hyeun Kim Doo Kim Geun-Shik Lee | 2018 | Cellular & Molecular Immunology2018，15，2： | 7 |
| 3 | Risk factors of biliary intervention by imaging after livingdonor liver transplantation显示文摘AIM:To determine the risk factors of biliary intervention using magnetic resonance cholangiopancreatography(MRCP) after living donor liver transplantation(LDLT).METHODS: We retrospectively enrolled 196 patients who underwent right lobe LDLT between 2006 and 2010 at a single liver transplantation center. Direct duct-to-duct biliary anastomosis was performed in all 196 patients. MRCP images routinely taken 1 mo after LDLT were analyzed to identify risk factors for biliary intervention during follow-up, such as retrograde cholangiopancreatography or percutaneous transhepatic biliary drainage. Two experienced radiologists evaluated the MRCP findings, including the anastomosis site angle on three-dimensional images, the length of the filling defect on maximum intensity projection, bile duct dilatation, biliary stricture, and leakage.RESULTS: Eighty-nine patients underwent biliary intervention during follow-up. The anastomosis site angle [hazard ratio(HR) = 0.48; 95% confidence interval(CI), 0.30-0.75, P < 0.001], a filling defect in the anastomosis site(HR = 2.18, 95%CI: 1.41-3.38,P = 0.001), and biliary leakage(HR = 2.52, 95%CI: 1.02-6.20, P = 0.048) on MRCP were identified in the multivariate analysis as significant risk factors for biliary intervention during follow-up. Moreover, a narrower anastomosis site angle(i.e., below the median angle of 113.3°) was associated with earlier biliary intervention(38.5 ± 4.2 mo vs 62. 1 ± 4.1 mo, P < 0.001). Kaplan-Meier analysis comparing biliary intervention-free survival according to the anastomosis site angle revealed that lower survival was associated with a narrower anastomosis site angle(36.3% vs 62.0%, P < 0.001).CONCLUSION: The biliary anastomosis site angle in MRCP after LDLT may be associated with the need for biliary intervention. | Soon Kyu Lee Jong Young Choi Dong Myung Yeo Young Joon Lee Seung Kew Yoon Si Hyun Bae Jeong Won Jang Hee Yeon Kim Dong Goo Kim Young Kyoung You | 2016 | World Journal of Gastroenterology2016，22，7： | 4 |
| 4 | Comparative study of rendezvous techniques in post-liver transplant biliary stricture显示文摘AIM:To investigate the usefulness of a new rendezvous technique for placing stents using the Kumpe(KMP) catheter in angulated or twisted biliary strictures.METHODS:The rendezvous technique was performed in patients with a biliary stricture after living donor liver transplantation(LDLT) who required the exchange of percutaneous transhepatic biliary drainage catheters for inside stents.The rendezvous technique was performed using a guidewire in 19 patients(guidewire group) and using a KMP catheter in another 19(KMP catheter group).We compared the two groups retrospectively.RESULTS:The baseline characteristics did not differ between the groups.The success rate for placing inside stents was 100% in both groups.A KMP catheter was easier to manipulate than a guidewire.The mean procedure time in the KMP catheter group(1012 s,range:301-2006 s) was shorter than that in the guidewire group(2037 s,range:251-6758 s,P = 0.022).The cumulative probabilities corresponding to the procedure time of the two groups were significantly different(P = 0.008).The factors related to procedure time were the rendezvous technique method,the number of inside stents,the operator,and balloon dilation of the stricture(P < 0.05).In a multivariate analysis,the rendezvous technique method was the only significant factor related to procedure time(P = 0.010).The procedural complications observed included one case of mild acute pancreatitis and one case of acute cholangitis in the guidewire group,and two cases of mild acute pancreatitis in the KMP catheter group.CONCLUSION:The rendezvous technique involving use of the KMP catheter was a fast and safe method for placing inside stents in patients with LDLT biliary stricture that represents a viable alternative to the guidewire rendezvous technique. | Jae Hyuck Chang In Seok Lee Ho Jong Chun Jong Young Choi Seung Kyoo Yoon Dong Goo Kim Young Kyoung You Myung-Gyu Choi Sok Won Han | 2012 | World Journal of Gastroenterology2012，18，41： | 3 |
| 5 | Clinical impact of thrombus aspiration during primary percutaneous coronary intervention: Results from Korea Acute Myocardial Infarction Registry显示文摘 | Daisuke Hachinohe Myung Ho Jeong Shigeru Saito Min Chol Kim Kyung Hoon Cho Khurshid Ahmed Seung Hwan Hwang Min Goo Lee Doo Sun Sim Keun-Ho Park Ju Han Kim Young Joon Hong Youngkeun Ahn Jung Chaee Kang Jong Hyun Kim Shung Chull Chae Young Jo Kim Seung Ho H | 2012 | Journal of Cardiology2012，，3： | 1 |
| 6 | Facile fabrication of transparent superhydrophobic surfaces by spray deposition 显示文摘 | Hwang Ha Soo Kim Nam Hyun Lee Seung Goo | 2011 | Applied Materials Interfaces2011，3，7： | 1 |
| 7 | Different clinical outcomes of acute kidney injury according to acute kidney injury network criteria in patients between ST elevation and non-ST elevation myocardial infarction显示文摘 | Seung Hwan Hwang Myung Ho Jeong Khurshid Ahmed Min Chul Kim Kyung Hoon Cho Min Goo Lee Jum Suk Ko Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Young keun Ahn Jeong Gwan Cho Jong Chun Park Jung C | 2011 | International Journal of Cardiology2011，，1： | 1 |
| 8 | Isothermal crystallization behavior and mechanical properties of polylactide/carbon nanotube nanocomposites显示文摘 | Sang Ho Park Seung Goo Lee Seong Hun Kim | 2013 | Composites:Part A2013，46，： | 1 |
| 9 | Eutectic self-mixing method for the preparation of LiMn2O4 without any artificial mixing procedures 显示文摘 | Hyun Koo Kang Wook Ahn Seung Goo Lee | 2006 | Journal of Power Sources2006，163，： | 1 |
| 10 | Gd-EOB-DTPA-Enhanced MRI is Better than MDCT in Decision Making of Curative Treatment for Hepatocellular Carcinoma显示文摘 | Sun Hong Yoo Jong Young Choi Jeong Won Jang Si Hyun Bae Seung Kew Yoon Dong Goo Kim Young Kyoung Yoo Sung Eun Rha Young Joon Lee Eun Sun Jung | 2013 | Annals of Surgical Oncology2013，，9： | 1 |
| 11 | Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity显示文摘 | Mi Jang Hyo Jin Kang Sun Young Lee Sang J. Chung Sunghyun Kang Seung Wook Chi Sayeon Cho Sang Chul Lee Chong-Kil Lee Byoung Chul Park Kwang-Hee Bae Sung Goo Park | 2009 | Molecules and Cells2009，，6： | 1 |
| 12 | Outcomes for four-part proximal humerus fractures treated with a locking compression plate and an autologous iliac bone impaction graft显示文摘 | Sae Hoon Kim Young Ho Lee Seok Won Chung Seung Han Shin Woo Young Jang Hyun Sik Gong Goo Hyun Baek | 2012 | Injury2012，，10： | 1 |
| 13 | Licochalcone A induces apoptosis in KB human oral cancer cells via acaspase-dependent FasL signaling pathway显示文摘 | Jae-Sung Kim Mi-Ra Park Sook-Young Lee Do Kim Sung?Min Moon Chun Kim Seung Cho Goo Yoon Hee-Jeong Im Jae?Seek You Ji-Su Oh Su-Gwan Kim | 2014 | Oncology Reports2014，，2： | 1 |
| 14 | The effect of initial serum neuron - specific enolase level on clinical outcome in acute carotid artery territory infarction显示文摘 | Oh Seung Hun Lee Jin Goo Na Sang Jun | 2002 | Yonsei Med J2002，43，3： | 1 |
| 15 | Hepatocellular carcinoma risk in chronic hepatitis B virus–infected compensated cirrhosis patients with low viral load显示文摘 | Dong Hyun Sinn Junggyu Lee Juna Goo Kyunga Kim Geum‐Youn Gwak Yong‐Han Paik Moon Seok Choi Joon Hyeok Lee Kwang Cheol Koh Byung Chul Yoo Seung Woon Paik | 2015 | Hepatology2015，，3： | 1 |
| 16 | Serum C‐reactive protein is a useful biomarker for predicting outcomes after liver transplantation in patients with hepatocellular carcinoma显示文摘 | Ho Jung An Jeong Won Jang Si Hyun Bae Jong Young Choi Seung Kew Yoon Myung Ah Lee Young Kyoung You Dong Goo Kim Eun Sun Jung | 2012 | Liver Transpl2012，，12： | 1 |
| 17 | Effect of filler-filler interaction on rheological behaviour of natural rubber compounds filledwith both earbon black and silica显示文摘 | Sung-Seen Choi Changwoon Nah Seung Goo Lee | 2003 | Polymer International2003，52，1： | 1 |
| 18 | Outcomes for four-part proximal humerus fractures treated with a locking compression plate and an autologous iliac bone impaction graft显示文摘 | Sae Hoon Kim Young Ho Lee Seok Won Chung Seung Han Shin Woo Young Jang Hyun Sik Gong Goo Hyun Baek | 2012 | Injury2012，，10： | 1 |
| 19 | Different clinical outcomes of acute kidney injury according to acute kidney injury network criteria in patients between ST elevation and non-ST elevation myocardial infarction显示文摘 | Seung Hwan Hwang Myung Ho Jeong Khurshid Ahmed Min Chul Kim Kyung Hoon Cho Min Goo Lee Jum Suk Ko Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Young keun Ahn Jeong Gwan Cho Jong Chun Park Jung C | 2011 | International Journal of Cardiology2011，，1： | 1 |
| 20 | Exploring ideal operative time for best outcomes in gastric cancer surgery:A multi-institutional study based on KLASS-07 database显示文摘Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher morbidity.Nevertheless,the optimal operative time range remains uncertain.This study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer surgery.Methods:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively reviewed.The ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful surgeries.Finally,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time groups.Results:The statistically calculated ideal operative time was 135.4-165.4 min.The longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all P<0.05).Longer operative time increased bleeding,postoperative morbidities,and delayed diet and discharge(all P<0.05).Particularly,an uneventful,perfect surgery could not be achieved when the operative time exceeded 240 min.Regardless of ideal time range,SOT group achieved the highest percentage of uneventful surgery(13.4%),which was possible by surgeon's ability to retrieve a higher number of lymph nodes and perform≥150 gastrectomies annually.Conclusions:Operative time longer than the ideal time range(especially≥240 min)should be avoided.If the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better prognosis.Efforts to minimize operative time should be attempted with sufficient surgical experience. | Shin-Hoo Park Ye-Rim Shin Hoon Hur Chang Min Lee Jae Seok Min Seung Wan Ryu Hyun Dong Chae Oh Jeong Chang-In Choi Kyo-Young Song Ho Goon Kim Ye Seob Jee Kwang Hee Kim Jeong Goo Kim Kyung Sook Yang Hua Huang Sungsoo Park | 2023 | Chinese Journal of Cancer Research2023，35，6： | 0 |
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