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| 1 | Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment显示文摘The molecular targets of sunitinib are receptor tyrosine kinases (RTKs),and this drug has also been known to exert blocking effects on the activation of KIT,which is similar to the mechanism of action of imatinib. Moreover,sunitinib has an additional anti-angiogenic effect through its inhibition of the vascular endothelial growth factor receptor activation. We report here a 70-year-old patient diagnosed with a recurrent gastrointestinal stromal tumor (GIST),which invaded the transverse colon and led to a perforation during sunitinib treatment. A computed tomography scan and 3-dimensional reconstruction showed necrosis of the recurrent hepatic mass and perforation of the invaded transverse colon. After percutaneous drainage of the intraperitoneal abscess,antibiotic treatment and restricted diet,the condition of the patient improved. The present case is the first to report that sunitinib,which is administered to treat GIST resistant to imatinib,can cause unexpected colon perforation and subsequent peritonitis. | Hoon Hur Ae Ryoung Park Sung Bae Jee Seung Eun Jung Wook Kim Hae Myung Jeon | 2008 | World Journal of Gastroenterology2008，14，39： | 3 |
| 2 | Undiagnosed Borrmann type Ⅱ gastric cancer due to necrosis and regenerative epithelium显示文摘Endoscopic biopsy is essential to the proper diagnosis and treatment of gastric cancer.Unfortunately,the results of endoscopic biopsy are not always the same as what is expected based on gross endoscopic findings.The results of endoscopic biopsy can be negative for malignancy in Borrmann typeⅣadvanced gastric cancer(AGCa)or gastric lymphoma.However,in the case of typeⅡAGCa,repeated biopsies negative for malignancy have not been reported.A 49-year-old male patient underwent esophagogastroduodenoscopy three times due to large gastric ulcer suspected to be Borrmann typeⅡcancer.However,three repeat endoscopic biopsies with multiple specimens showed necrosis and superficial regenerative epithelium without malignant findings.The patient underwent laparoscopic distal gastrectomy with D2 lymph node dissection.The surgical specimen revealed that the mucosal layer was completely replaced with regenerative epithelium without cancer cells. | Joon Hur Jae Hyuck Chang Byung Kee Kim Hoon Young Ko Jong Hwan Lee Soo Jeong Kim Mi Ae Song Tae Ho Kim Chang Whan Kim Sok Won Han | 2014 | World Journal of Gastroenterology2014，20，28： | 2 |
| 3 | Laparoscopy-Assisted Endoscopic Full-Thickness Resection with Basin Lymphadenectomy Based on Sentinel Lymph Nodes for Early Gastric Cancer显示文摘 | Hoon Hur Sun Gyo Lim Cheulsu Byun Joon Koo Kang Sung Jae Shin Kee Myung Lee Jin Hong Kim Yong Kwan Cho Sang-Uk Han | 2014 | Journal of the American College of Surgeons2014，，3： | 2 |
| 4 | Standardization of D2 lymphadenectomy and surgical quality control (KLASS-02-QC) : a prospective, observational,multicenter study 显示文摘 | Hyoung-Ⅱ Kim Hoon Hur Youn Nam Kim | 2014 | BMC Cancer2014，14，： | 1 |
| 5 | Magnetic resonance imaging findings of the mass‐forming type of autoimmune pancreatitis: Comparison with pancreatic adenocarcinoma显示文摘 | Bo Yun Hur Jeong Min Lee Jeong Eun Lee Jae Yong Park Soo Jin Kim Ijin Joo Cheong Il Shin Jee Hyun Baek Jung Hoon Kim Joon Koo Han Byung Ihn Choi | 2012 | J Magn Reson Imaging2012，，1： | 1 |
| 6 | Genome Sequences of Escherichia coli B strains REL606 and BL21(DE3)显示文摘 | Haeyoung Jeong Valérie Barbe Choong Hoon Lee David Vallenet Dong Su Yu Sang-Haeng Choi Arnaud Couloux Seung-Won Lee Sung Ho Yoon Laurence Cattolico Cheol-Goo Hur Hong-Seog Park Béatrice Ségurens Sun Chang Kim Tae Kwang Oh Richard E. Lenski F. William Stud | 2009 | Journal of Molecular Biology2009，，4： | 1 |
| 7 | Benefit of Early Statin Therapy in Patients With Acute Myocardial Infarction Who Have Extremely Low Low-Density Lipoprotein Cholesterol显示文摘 | Ki Hong Lee Myung Ho Jeong Ha Mi Kim Youngkeun Ahn Jong Hyun Kim Shung Chull Chae Young Jo Kim Seung Ho Hur In Whan Seong Taek Jong Hong Dong Hoon Choi Myeong Chan Cho Chong Jin Kim Ki Bae Seung Wook Sung Chung Yang Soo Jang Seung Woon Rha Jang Ho Bae Jeo | 2011 | Journal of the American College of Cardiology2011，，16： | 1 |
| 8 | Neuroprotective effects of the cyanidin-3- O -β- d -glucopyranoside isolated from mulberry fruit against cerebral ischemia显示文摘 | Tong Ho Kang Jin Young Hur Hyun Bok Kim Jong Hoon Ryu Sun Yeou Kim | 2005 | Neuroscience Letters2005，，3： | 1 |
| 9 | Evolution of the chemical bonding nature of ferroelectric bismuth titanate upon cation substitution显示文摘 | HUR SU GIL PARK DAE HOON KUM TAE WOO | 2004 | Appl Phys Lett2004，85，18： | 1 |
| 10 | Minimally Invasive Treatment of Gastric Gastrointestinal Stromal Tumors: Laparoscopic and Endoscopic Approach显示文摘 | In Ho Jeong Ji Hun Kim Sang Rim Lee Jin Hong Kim Jae Chul Hwang Sung Jae Shin Kee Myung Lee Hoon Hur Sang Uk Han | 2012 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2012，，3： | 1 |
| 11 | Operative Risk Factors in Gastric Cancer Surgery for Elderly Patients 显示文摘 | Su Han Seo Hoon Hur Chang Wook An | 2011 | J Gastric Cancer2011，11，2： | 1 |
| 12 | Effects of Early Oral Feeding on Surgical Outcomes and Recovery After Curative Surgery for Gastric Cancer: Pilot Study Results显示文摘 | Hoon Hur Yoon Si Won Kyung Kang | 2009 | World] Surg2009，33，： | 1 |
| 13 | Follow-Up Strategy After Curative Resection of Gastric Cancer: A Nationwide Survey in Korea显示文摘 | Hoon Hur Kyo Young Song Cho Hyun Park Hae Myung Jeon | 2010 | Annals of Surgical Oncology2010，，1： | 1 |
| 14 | Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as apotential therapeutic target显示文摘 | Hoon Hur Yi Xuan Young Kim Gwang Lee Wooyoung Shim Jisoo Yun In-Hye Ham Sang-Uk Han | 2013 | International Journal of Oncology2013，，1： | 1 |
| 15 | In vitro antigenotoxic activity of novel ginseng saponin metabolites formed by intestinal bacteria显示文摘 | Byung - Hoon Lee Sang - Jun Lee Jang - Hyun Hur Sooyong Lee Jong - Hwansung Jae- Doo Huh Chang - Kiu Mcon | 1998 | Planta Meal1998，64，6： | 1 |
| 16 | Thymidylate synthase and ERCC1 as predictive markers in patients with pulmonary adenocarcinoma treated with pemetrexed and cisplatin显示文摘 | Seung Hyeun Lee Kyung Bo Noh Ji Sung Lee Eun Joo Lee Kyung Hoon Min Gyu Young Hur Seung Heon Lee Sung Yong Lee Je Hyeong Kim Sang Yeub Lee Chol Shin Jae Jeong Shim Chul Hwan Kim Kyung Ho Kang Kwang Ho In | 2013 | Lung Cancer2013，，： | 1 |
| 17 | Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment显示文摘 | HanByoul Cho Hye Won Hur Sang Wun Kim Sung Hoon Kim Jae Hoon Kim Young Tae Kim Kook Lee | 2009 | Cancer Immunology, Immunotherapy2009，，： | 1 |
| 18 | Neuroprotective effects of the cyanidin-3- O -β- d -glucopyranoside isolated from mulberry fruit against cerebral ischemia显示文摘 | Tong Ho Kang Jin Young Hur Hyun Bok Kim Jong Hoon Ryu Sun Yeou Kim | 2005 | Neuroscience Letters2005，，3： | 1 |
| 19 | Treatment of ovarian cancer with paclitaxel- or carboplatin-based intraperitoneal hyperthermic chemotherapy during secondary surgery显示文摘 | Jeong Hoon Bae Joon Mo Lee Ki Sung Ryu Yong Seok Lee Yong Gyu Park Soo Young Hur Woong Shik Ahn Seong Eun Namkoong | 2007 | Gynecologic Oncology2007，，1： | 1 |
| 20 | Cassiae semen, a seed of Cassia obtusifolia , has neuroprotective effects in Parkinson’s disease models显示文摘 | Mi Sun Ju Hyo Geun Kim Jin Gyu Choi Jong Hoon Ryu Jinyoung Hur Youn Jung Kim Myung Sook Oh | 2010 | Food and Chemical Toxicology2010，，8： | 1 |
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