|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Geological characteristics of shale rock system and shale oil exploration breakthrough in a lacustrine basin:A case study from the Paleogene 1st sub-member of Kong 2 Member in Cangdong sag,Bohai Bay Basin,China显示文摘A deep understanding of the basic geologic characteristics of the fine-grained shale layers in the Paleogene 1 st sub-member of Kong 2 Member(Ek_2~1) in Cangdong sag, Bohai Bay Basin, is achieved through observation of 140 m continuous cores and systematic analysis of over 1 000 core samples from two wells. Basic geological conditions for shale oil accumulation are proposed based on the unconventional geological theory of oil and gas. The shale rock system mainly developed interbedded formation of felsic shale, calcareous and dolomitic shale and carbonates; high quality hydrocarbon source rock formed in the stable and closed environment is the material base for shale oil enrichment; intergranular pores in analcite, intercrystalline pores in dolomite and interlayer micro-fractures make tight carbonate, calcareous and dolomitic shale and felsic shale effective reservoirs, with brittle mineral content of more than 70%; high abundance laminated shale rock in the lower section of Ek_2~1 is rich in shale oil, with a total thickness of 70 m, burial depth between 2 800 to 4 200 m, an average oil saturation of 50%, a sweet spot area of 260 km^2 and predicted resources of over 5×10~8 t. Therefore, this area is a key replacement domain for oil exploration in the Kongdian Formation of the Cangdong sag. At present, the KN9 vertical well has a daily oil production of 29.6 t after fracturing with a 2 mm choke. A breakthrough of continental shale oil exploration in a lacustrine basin is expected to be achieved by volume fracturing in horizontal wells. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming HAN Wenzhong XIAO Dunqing CHEN Shiyue SHI Zhannan ZHANG Wei YANG Fei | 2018 | Petroleum Exploration and Development2018，45，3： | 8 |
| 3 | Theories,technologies and practices of lacustrine shale oil exploration and development:A case study of Paleogene Kongdian Formation in Cangdong sag,Bohai Bay Basin,China显示文摘As the main factors affecting stable and high production and the production regularity of lacustrine shale oil are unclear,the theoretical understandings,key exploration and development technologies,development effect and production regularity of lacustrine shale oil have been analyzed and summarized based on 700 m cores taken systematically from Paleogene Kong 2 Member of 4 wells in Cangdong sag,over 100000 analysis data and formation testing data.Three theoretical understandings on shale oil enrichment and high production have been reached:(1)High-quality shale with“three highs and one low”is the material base for shale oil enrichment.(2)Medium-slightly high thermal evolution degree is the favorable condition for shale oil enrichment.(3)Laminar felsic shale is the optimal shale layer for oil enrichment in semi-deep lake facies.Key exploration and development technologies such as shale oil enrichment layer and area evaluation and prediction,horizontal well pattern layout,shale oil reservoir fracturing,optimization of shale oil production regime have been established to support high and stable shale oil production.Under the guidance of these theoretical understandings and technologies,shale oil in Cangdong sag has achieved high and stable production,and 4 of them had the highest production of over 100 tons a day during formation testing.In particular,Well GY5-1-1 L had a daily oil production of 208 m^(3).By April,2022,the 28 wells combined have a stable oil production of 300–350 tons a day,and have produced 17.8×10^(4) t of oil cumulatively.It is found that the shale oil production of horizontal well declines exponentially in natural flow stage,and declines in step pattern and then tends stable in the artificial lift stage.Proportion of light hydrocarbons in produced shale oil is in positive correlation with daily oil production and decreases regularly during production test. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming HAN Wenzhong SHI Zhannan CHEN Changwei JIANG Wenya GUAN Quansheng XU Jing LIU Xuewei ZHANG Wei MA Jianying | 2022 | Petroleum Exploration and Development2022，49，3： | 4 |
| 4 | Geological characteristics and key exploration technologies of continental shale oil sweet spots: A case study of Member 2 of Kongdian Formation in the Cangdong sag in the Huanghua depression, Bohai Bay Basin显示文摘Under the general trend of stepping-up oil and gas exploration and development in China,the unconventional oil and gas resources such as shale oil and gas have become an important alternative.Abundant continental shale oil resources are developed in Member 2 of Kongdian Formation(Ek2)of the Cangdong sag in the Huanghua depression of the Bohai Bay Basin which has complex structure,strong heterogeneity,and large buried depth,thus,the geological characteristic of shale oil accumulation and key exploration technologies are investigated on base of the system coring of 635.8 m,centimeter-level fine description and analysis of over ten thousand samples,therefore,the“four accurate”technologies have been developed,including the accurate selection of sweet spot areas,accurate drilling of sweet spot layers,accurate fracturing of sweet spot layers and accurate measure of fracture-rich sections.The results show that the continental shale strata in Member 2 of Kongdian Formation can be divided into three types:felsic shale,limy dolomitic shale and mixed shale.The Member 2 of Kongdian Formation is characterized by diverse mineral components,abundant laminae,good source rocks and medium thermal evolution degree,tight reservoir with rich micropore and microfractures,high oil saturation and brittle mineral content,indicating good prospect of shale oil exploration.Through sedimentological study,TOC and Ro evaluation,brittle mineral calculation,and seismic fusion inversion,a total of 126 km^(2) of Class I sweet spots in Member 2 of Kongdian Formation was delineated comprehensively,which guides horizontal well deployment(Well GD1701H and Well GD1702H).The drilling rate of sweet spot of these two horizontal wells is up to 96%by tracing thin layer through fine calibration,locating compartment through fine inversion,ensuring window entry through precise positioning,and tracking sweet spot through adjustment.The “one-excellent and five-highs”criterion is used to select perforation points to realize differential designs of fracturing intervals and clusters.Micro-seismic and potentiometry monitoring show that the artificial fractures formed by volumetric fracturing are 300e400 m long and 120 m high,and control a volume of about 0.07 km^(3).The maximum daily oil production of two horizontal wells is 48 t and 66 t respectively to realize the economic exploitation of shale oil reserves controlled by fractures.The shale oil exploration in Member 2 of Kongdian Formation shows that the continental shale oil has great potential of exploration and development,and the above technologies are critical and effective for shale oil efficient recovery. | Xianzheng Zhao Xiugang Pu Fengming Jin Wenzhong Han Zhannan Shi Aibing Cai Aiguo Wang Quansheng Guan Wenya Jiang Wei Zhang | 2019 | Petroleum Research2019，4，2： | 2 |
| 5 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47hqqpc5xfpo9on6bfo.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 6 | Susceptibility behaviour and specific heat anomaly in single crystals of alanine and valine显示文摘 | Wenqing Wang Xiangrong Sheng Haofang Jin Jilan Wu Bo Yin Jingwei Li Zhongxian Zhao Hongshun Yang Fengming Lou Zhizhong Zhuang Guanyuan Yu Lei Shi Zhaojia Chen | 1996 | Journal of Biological Physics1996，，2： | 1 |
| 7 | Sweet spot evaluation and exploration practice of lacustrine shale oil of the second member of Kongdian Formation in Cangdong sag, Bohai Bay Basin显示文摘Based on core,thin section,X-ray diffraction,rock pyrolysis,CT scanning,nuclear magnetic resonance and oil testing data,the macro and micro components,sedimentary structure characteristics,of Paleogene Kong 2 Member in Cangdong sag of Huanghua depression and evaluation standard and method of shale oil reservoir were studied to sort out the best shale sections for shale oil horizontal wells.According to the dominant rock type,rhythmic structure and logging curve characteristics,four types of shale lithofacies were identified,namely,thin-layered dolomitic shale,lamellar mixed shale,lamellar felsic shale,and bedded dolomitic shale,and the Kong 21 sub-member was divided into four quasi-sequences,PS1 to PS4.The PS1 shale has a porosity higher than 6%,clay content of less than 20%,and S1 of less than 4 mg/g;the PS2 shale has well-developed laminar structure,larger pore and throat size,better connectivity of pores and throats,high contents of TOC and movable hydrocarbon,S1 of over 4 mg/g,clay content of less than 20%,and porosity of more than 4%;PS3 shale has S1 value higher than 6 mg/g and clay content of 20%-30%,and porosity of less than 4%;and PS4 shale has lower TOC content and low oil content.Shale oil reservoir classification criterion based on five parameters,free hydrocarbon content S1,shale rhythmic structure,clay content,TOC and porosity,was established.The evaluation method of shale oil sweet spot by using the weighted five parameters,and the evaluation index EI were proposed.Through comprehensive analysis,it is concluded that PS2 is best in quality and thus the dual geological and engineering sweet spot of shale oil,PS3 and PS1 come next,the former is more geologic sweet spot,the latter more engineering sweet spot,and PS4 is the poorest.Several vertical and horizontal wells drilled in the PS2 and PS3 sweet spots obtained high oil production.Among them,Well 1701 H has produced stably for 623 days,with cumulative production of over 10000 tons,showing bright exploration prospects of Kong 2 Member shale oil. | HAN Wenzhong ZHAO Xianzheng JIN Fengming PU Xiugang CHEN Shiyue MU Liangang ZHANG Wei SHI Zhannan WANG Hu | 2021 | Petroleum Exploration and Development2021，48，4： | 1 |
| 8 | Ginkgo biloba extract in Alzhei- mer's disease:From action mechanisms to medical practice 显示文摘 | Shi Chun Liu Jun Wu Fengming | 2010 | Int J Mol Sci2010，11，1： | 1 |
| 9 | A new route to fabricate SiB4 modified C/SiC composites 显示文摘 | Shi Fengming Yin Xiaowei Fan Xiaomeng | 2010 | Journal of the European Ceramic Society2010，，30： | 1 |
| 10 | Dual Effects of Light on Regulating Aedes aegypti Heat-Seeking Behavior显示文摘Dear Editor,Mosquitoes,as important arthropod disease vectors,efficiently transmit pathogens such as dengue virus,Zika virus,yellow fever virus,and malaria.To find their host,female mosquitoes use multiple sensory systems to detect host-associated cues such as CO_(2),volatile odorants,visual signals,and temperature. | Haonan Zhou Kai Shi Fengming Wu Bingcai Wang Jing Li Bowen Deng Chuan Zhou | 2022 | Neuroscience Bulletin2022，38，11： | 0 |
| 11 | Tropical Timber Trade Flows in P.R. China显示文摘The historical transition of timber distribution pattern in China was presented firstly with main parts of timber flows in China,which included timber markets,timber transport system and regulations of timber transport.Based on the overview on tropical timber flows in China,the trade flows of tropical timber from production and imports of tropical timber to export of tropical timber products were analyzed by vivid illustrations.At the same time,problems in timber trade flows in China were analysed in the end. | HU Yanjie LIN Fengming SHI Kunshan | 2007 | Chinese Forestry Science and Technology2007，6，2： | 0 |
| 12 | Possible Transition in D-Valine and L-Valine Single Crystal Samples显示文摘The specific heats and temperature dependence of the x-ray powder diffractions for the D-valine and the L-valine single crystal samples have been studied.It is found that there is a specific heat jump at 272.0K for the D-dine samples but no jump at the same temperature for the L-dine sample.The lambda like transition means that the co-operative effect is involved in this transition.There is no crystal structure transition in the temperature range of 123-293K for the D-dine sample.The transition of the D-valine sample might be the possible D-L transition which is proposed by Abdus Salam. | YANG Hongshun LOU Fengming WANG Wenqing SHENG Xiangrong ZHUANG Zhizhong SHI Lei CHEN Zhaojia | 1995 | Chinese Physics Letters1995，12，5： | 0 |
| 13 | Pre-operative nasal probe tests with adrenaline and lidocaine ease insertion during flexible bronchoscopy and reduce post-operative bleeding:a randomized controlled trial显示文摘Background:Nasal insertion is the preferred method for non-intubated patients in flexible bronchoscopy;however,the relatively narrow nasal cavity results in difficulties related to bronchoscope insertion.This study aimed to investigate whether pre-operative nasal probe tests could reduce the time to pass the glottis,improve the first-pass success rate and patients’tolerance,and reduce postoperative bleeding.Methods:This three-arm prospective randomized controlled trial was conducted in a tertiary hospital between May and October 2020.Three hundred patients requiring diagnosis and treatment using flexible bronchoscopy were randomly allocated to three groups:control group,simple cotton bud detection group(CD group),and adrenaline+lidocaine detection group(AD group).The primary outcome was the time to pass the glottis.Secondary outcomes included the first-pass success rate,the patients’tolerance scores,and post-operative bleeding.One-way analysis of variance,Kruskal-WallisH test,Chi-squared test,Fisher’s exact test,and Bonferroni’s multiple comparison tests were used in this study.Results:In total,189 men and 111 women were enrolled in this study,with a mean age of 55.72±12.86 years.The insertion time was significantly shorter in the AD group than in the control group(18.00 s[12.00–26.50 s]vs.24.00 s[14.50–45.50 s],P=0.005).Both the AD(99%vs.83%,χ2=15.62,P<0.001)and CD groups(94%vs.83%,χ2=5.94,P=0.015)had a significantly higher first-pass success rate than the control group.Compared with the control group,post-operative bleeding(1%vs.13%,χ2=11.06,P<0.001)was significantly lower in the AD group.However,no significant difference was found in the patients’tolerance scores.Conclusions:Pre-operative nasal cavity probe tests especially with adrenaline and lidocaine during flexible bronchoscopy can significantly reduce the time to pass the glottis,improve the first-pass success rate,and reduce post-operative nasal bleeding.Pre-operative nasal probe tests are recommended as a time-saving procedure for patients undergoing flexible bronchoscopy.Trial registration:Chinese Clinical Trial Registry(ChiCTR),ChiCTR2000032668;http://gffzz62a03ee25e6f4a77hqqpc5xfpo9on6bfo.ffgz.tsg.suse.edu.cn/showprojen.aspx?proj=53321. | Wenjun Zhu Yuchen Zhang Jingyu Shi Xiaoqin Wang Renjiao Li Jia Liu Ping Li Dan Liu Fengming Luo | 2022 | Chinese Medical Journal2022，，15： | 0 |
| 14 | Cycles of fine-grained sedimentation and their influences on organic matter distribution in the second member of Paleogene Kongdian Formation in Cangdong Sag,Bohai Bay Basin,East China显示文摘According to the theory of sequence stratigraphy based on continental transgressive-regressive(T-R)cycles,a 500 m continuous core taken from the second member of Kongdian Formation(Kong 2 Member)of Paleogene in Well G108-8 in the Cangdong Sag,Bohai Bay Basin,was tested and analyzed to clarify the high-frequency cycles of deep-water fine-grained sedimentary rocks in lacustrine basins.A logging vectorgraph in red pattern was plotted,and then a sequence stratigraphic framework with five-order high-frequency cycles was formed for the fine-grained sedimentary rocks in the Kong 2 Member.The high-frequency cycles of fine-grained sedimentary rocks were characterized by using different methods and at different scales.It is found that the fifth-order T cycles record a high content of terrigenous clastic minerals,a low paleosalinity,a relatively humid paleoclimate and a high density of laminae,while the fifth-order R cycles display a high content of carbonate minerals,a high paleosalinity,a dry paleoclimate and a low density of laminae.The changes in high-frequency cycles controlled the abundance and type of organic matter.The T cycles exhibit relatively high TOC and abundant endogenous organic matters in water in addition to terrigenous organic matters,implying a high primary productivity of lake for the generation and enrichment of shale oil. | ZHAO Xianzheng PU Xiugang YAN Jihua JIN Fengming SHI Zhannan CHAI Gongquan HAN Wenzhong LIU Yan JIANG Wenya CHEN Changwei ZHANG Wei FANG Zheng XIE Delu | 2023 | Petroleum Exploration and Development2023，50，3： | 0 |
| 15 | Herbal small RNAs in patients with COVID-19 linked to reduced DEG expression显示文摘In China,more than 80%of patients with coronavirus disease 2019(COVID-19)received traditional Chinese medicine(TCM)as a treatment and their clinical efficacy have been reported.However,the underlying molecular mechanism remains unclear.Previous studies have identified herbal small RNAs(s RNAs)as novel functional components.In this study,a cohort of 22patients with COVID-19 treated with Toujie Quwen(TQ)granules was analyzed.We observed thousands of herbal small RNAs that entered the blood cells of patients after the consumption of TQ granules.In response to this treatment,the reduced differentially expressed genes(DEGs)were highly correlated with the predicted target genes of the most prevalent herbal s RNAs detected in the blood.Moreover,the predicted target genes of the top 30 s RNAs from each of the 245 TCMs in the Bencao s RNA Atlas overlapped with 337 upregulated DEGs in patients with mild COVID-19,and 33 TCMs,with more than 50%overlapping genes were identified as effective TCMs.These predicted target genes of top 30 s RNAs from Juhong,Gualoupi and Foshou were confirmed experimentally.Our results not only elucidated a novel molecular mechanism of TCM potential clinical efficacy for COVID-19 patients,but also provided 33 effective COVID-19 TCMs for prescription optimization. | Xiangyu Qiao Fengming Huang Xiaohu Shi Xingyu Deng Cong Zhang Song Mei Zhiqing Wang Congzhao Zhou Chengyu Jiang Xinghua Tan | 2023 | Science China(Life Sciences)2023，66，6： | 0 |
| 16 | Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus显示文摘Insulin-producing pancreaticβcell death is the fundamental cause of type 1 diabetes(T1D)and a contributing factor to type 2 diabetes(T2D).Moreover,metabolic disorder is another hallmark of T2D.Mammalian sterile 20-like kinase 1(MST1)contributes to the progression of diabetes mellitus through apoptosis induction and acceleration of pancreaticβcell dysfunction.AMP-activated protein kinase(AMPK)is an energy sensing kinase and its activation has been suggested as a treatment option for metabolic diseases.Thus,pharmacological inhibition of MST1 and activation of AMPK simultaneously represents a promising approach for diabetes therapy.Here,we discovered a novel selective MST1 kinase inhibitor IHMT-MST1-39,which exhibits anti-apoptosis efficacy and improves the survival of pancreaticβcells under diabetogenic conditions,as well as primary pancreatic islets in an ex vivo disease model.Mechanistically,IHMT-MST1-39 activated AMPK signaling pathway in hepatocytes in vitro,combination of IHMT-MST1-39 and metformin synergistically prevented hyperglycemia and significantly ameliorated glucose tolerance and insulin resistance in diabetic mice.Taken together,IHMT-MST1-39 is a promising anti-diabetic candidate as a single agent or in combination therapy for both T1D and T2D. | Junjie Wang Ziping Qi Yun Wu Aoli Wang Qingwang Liu Fengming Zou Beilei Wang Shuang Qi Jiangyan Cao Chen Hu Chenliang Shi Qianmao Liang Li Wang Jing Liu Wenchao Wang Qingsong Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 0 |
| 17 | A Neural Circuit Controlling Virgin Female Aggression Induced by Mating-related Cues in Drosophila显示文摘Females increase aggression for mating opportunities and for acquiring reproductive resources.Although the close relationship between female aggression and mating status is widely appreciated,whether and how female aggression is regulated by mating-related cues remains poorly understood.Here we report an interesting observation that Drosophila virgin females initiate high-frequency attacks toward mated females.We identify 11-cis-vaccenyl acetate(cVA),a male-derived pheromone transferred to females during mating,which promotes virgin female aggression.We subsequently reveal a cVA-responsive neural circuit consisting of four orders of neurons,including Or67d,DA1,aSP-g,and pC1 neurons,that mediate cVA-induced virgin female aggression.We also determine that aSP-g neurons release acetylcholine(ACh)to excite pC1 neurons via the nicotinic ACh receptor nAChRα7.Together,beyond revealing cVA as a mating-related inducer of virgin female aggression,our results identify a neural circuit linking the chemosensory perception of mating-related cues to aggressive behavior in Drosophila females. | Xiaolu Wan Peng Shen Kai Shi Jing Li Fengming Wu Chuan Zhou | 2023 | Neuroscience Bulletin2023，39，9： | 0 |
| 18 | Effect of Peroxiredoxin 1 on the biological function of airway epithelial cells and epithelial-mesenchymal transition显示文摘Peroxiredoxin 1(PRDX1)participates in tumor cell proliferation,apoptosis,migration,invasion,and the epithelial-to-mesenchymal transition(EMT).This study aimed to investigate the effect of PRDX1 on the EMT of airway epithelial cells stimulated with lipopolysaccharide(LPS)and transforming growth factor-beta 1(TGF-β1).PRDX1 overexpression significantly increased the proliferation and migration of human bronchial epithelial(BEAS-2B)cells,reduced cell apoptosis(p<0.01),and induced EMT and collagen deposition by upregulating the expression of the matrix metallopeptidase(MMP)2,MMP9,α-smooth muscle actin(α-SMA),N-cadherin,vimentin and twist proteins and inhibiting E-cadherin expression(p<0.05).PRDX1 overexpression promoted TGF-β1-mediated inhibition of cell proliferation and migration and significantly enhanced the TGF-β1-induced EMT and collagen synthesis(p<0.05).Knockdown of PRDX1 inhibited cell proliferation,migration,EMT,and collagen synthesis(p<0.01),reversed LPS-mediated inhibition of cell proliferation and migration,and significantly suppressed LPS-induced EMT and collagen synthesis(p<0.01).The result indicating that PRDX1 may be involved in LPS/TGF-1-induced EMT and collagen synthesis in human bronchial epithelial cells. | HUOGEN LIU YUNDI SHI XIN WAN YING LIU HAILIN SHU FENGMING HUANG ZHENBIN GONG LING GU | 2022 | BIOCELL2022，46，12： | 0 |
| 19 | Simulation of Dynamic Recrystallization in 7075 Aluminum Alloy Using Cellular Automaton显示文摘The evolution of microstructure during hot deformation is key to achieving good mechanical properties in aluminum alloys.We have developed a cellular automaton(CA) based model to simulate the microstructural evolution in 7075 aluminum alloy during hot deformation.Isothermal compression tests were conducted to obtain material parameters for 7075 aluminum alloy,leading to the establishment of models for dislocation density,nucleation of recrystallized grains,and grain growth.Integrating these aspects with grain topological deformation,our CA model effectively predicts flow stress,dynamic recrystallization(DRX) volume fraction,and average grain size under diverse deformation conditions.A systematic comparison was made between electron back scattered diffraction(EBSD) maps and CA model simulated under different deformation temperatures(573 to 723 K),strain rates(0.001 to 1 s^(-1)),and strain amounts(30% to 70%).These analyses indicate that large strain,high temperature,and low strain rate facilitate dynamic recrystallization and grain refinement.The results from the CA model show good accuracy and predictive capability,with experimental error within 10%. | 赵晓东 SHI Dongxing 李亚杰 QIN Fengming CHU Zhibing YANG Xiaorong | 2024 | Journal of Wuhan University of Technology(Materials Science)2024，39，2： | 0 |
| 20 | Efficacy of bronchoscopic thermal vapor ablation in patients with heterogeneous emphysema and lobar quantification by three-dimensional ventilation/perfusion single-photon emission computed tomography/computed tomography: a prospective pilot study from China显示文摘Chronic obstructive pulmonary disease(COPD)is characterized by emphysema and airflow limitation and is one of the leading causes of morbidityand mortalityworldwide.Endoscopic lung volumereduction(ELVR)is a minimally invasive technique for patients with severe hyperinflation and advanced emphysema.To date,the most investigated form of ELVR isvalve implantation,which is toplacevalves in all the segments of an emphysematous lobe.However,valve replacements do not achieve adequate lung volume reduction in the,presence of interlobar collateral ventilation(CV).l1 in addition,with the heterogeneity existing withinthe treatment lobe,complete lobar treatment from implants may result in excessive reduction of the less diseased segments.Thus,a more targeted approach of the most severe emphysematous parts of the lobe is warranted. | Wenjun Zhu Yuchen Zhang Felix J.F.Herth Dan Liu Hui Zhu Jingyu Shi Chujie Zhang Gongshun Tang Fengming Luo | 2022 | Chinese Medical Journal2022，135，17： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员