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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Plowing-Extrusion Processes and Performance of Functional Surface Structures of Copper Current Collectors for Lithium-Ion Batteries显示文摘Most copper current collectors for commercial lithium-ion batteries(LIBs)are smooth copper foils,which cannot form a stable and effective combination with electrode slurry.They are likely to deform or fall off after long-term operation,resulting in a sharp decline in battery performance.What is worse is that this condition inevitably causes internal short circuits and thus brings about security risks.In this study,a process route of fabricating the functional surface structures on the surface of a copper collector for LIBs by twice-crisscross micro-plowing(TCMP)is proposed,which provides a new idea and an efficient method to solve the above problems from the perspective of manufacturing.The finite element simulation of TCMP combined with the cutting force test and morphological characterization is conducted to verify the forming mechanism of the surface structures on a copper sheet and its relationship with the processing parameters.The influence of several key processing parameters on the surface characteristics of the copper sheet is comprehensively explored.A series of functions is tested to obtain the optimal parameters for performance improvement of the current collector.Results show that the structured copper sheet with the cutting distance of 250μm,cutting depth of 80μm,and cutting crossing angle of 90°enables the best surface features of the current collector;the contact angle reaches 0°,the slurry retention rate is up to 89.2%,and the friction coefficient reaches 0.074.The battery using the as-prepared structured copper sheet as the current collector produces a specific capacity of 318.6 mAh/g after 50 cycles at a current density of 0.2 C,which is 132.7%higher than the one based on a smooth surface.The capacity reversibility of the sample with the new current collector is much better than that of the traditional samples,yielding a lower impedance. | Chun Wang Wei Yuan Yu Chen Bote Zhao Yong Tang Shiwei Zhang Xinrui Ding Jun He Songmao Chen Baoyou Pan Mingyue Chen | 2022 | Nanomanufacturing and Metrology2022，5，4： | 2 |
| 3 | Propelling polysulfide redox by Fe_(3)C-FeN heterostructure@nitrogendoped carbon framework towards high-efficiency Li-S batteries显示文摘Lithium-sulfur(Li-S) batteries hold great promise in next-generation high-energy-density energy storage systems,but the intractable shuttle effect and the sluggish redox kinetics of polysulfides hinder the practical implementation of Li-S batteries.Here,heterostructured Fe_(3)C-FeN nanoparticles dotted in the threedimensional-ordered nitrogen-doped carbon framework(Fe_(3)C-FeN@NCF) were synthesized by molecular engineering combined with heterointerface engineering,and were applied to regulate the immobilization-diffusion-conversion behavior of polar polysulfides.It is experimentally and theoretically demonstrated that the heterointerface between Fe_(3)C and FeN exhibits high sulfiphilicity and high electronic/ionic conductivity,thus effectively capturing polysulfides and accelerating the bidirectional conversion of sulfur species.Meanwhile,the holey carbon framework functions as the scaffold to highly disperse binary nanoparticles,ensuring the sufficient exposure of active sites and the easy accessibility for lithium ions and electrons.By virtue of these synergistic merits,the Li-S batteries based on Fe_(3)CFeN@NCF-modified separators afford excellent electrochemical performances including a high rate capacity of 858 mA h g^(-1)at 2 C and a low capacity decay rate of 0.07% per cycle after 800 cycles at 1C This work provides inspiration for the design of heterostructured compounds and sheds light on the potential of heterostructure in high-efficiency Li-S batteries. | Mengdi Zhang Jiawei Mu Yanan Li Yuanyuan Pan Zhiliang Dong Bei Chen Shiwei Guo Wenhan Yuan Haiqiu Fang Han Hu Mingbo Wu | 2023 | Journal of Energy Chemistry2023，，3： | 1 |
| 4 | Preparation and characterization of amphiphilic starch nanocrystals显示文摘 | Song Shiwei Wang Cai Pan Zelin | 2008 | Journal of Applied Polymer Science2008，107，1： | 1 |
| 5 | Facet effect on the reconstructed Cu-catalyzed electrochemical hydrogenation of 5-hydroxymethylfurfural(HMF) towards 2,5-bis(hydroxymethy)furan (BHMF)显示文摘The electrochemical hydrogenation of HMF to BHMF is an elegant alternative to the conventio nal thermocatalytic route for the production of high-value-added chemicals from biomass resources.In virtue of the wide potential window with promising Faradic efficiency(FE) towards BHMF,Cu-based electrode has been in the center of investigation.However,its structure-activity relationship remains ambiguous and its intrinsic catalytic activity is still unsatisfactory.In this work,we develop a two-step oxidation-reduction strategy to reconstruct the surface atom arrangement of the Cu foam(CF).By combination of multiple quasi-situ/in-situ techniques and density functional theory(DFT) calculation,the critical factor that governs the reaction is demonstrated to be facet effect of the metallic Cu crystal:Cu(110) facet accounts for the most favorable surface with enhanced chemisorption with reactants and selective production of BHMF,while Cu(100) facet might trigger the accumulation of the by-product 5,5'-bis(hydroxy methy)hydrofurion(BHH).With the optimized composition of the facets on the reconstructed Cu(OH)_(2)-ER/CF,the performance could be noticeably enhanced with a BHMF FE of 92.3% and HMF conversion of 98.5% at a potential of -0.15 V versus reversible hydrogen electrode(vs.RHE) in 0.1 M KOH solution.This work sheds light on the incomplete mechanistic puzzle for Cu-catalyzed electrochemical hydrogenation of HMF to BHMF,and provides a theoretical foundation for further precise design of highly efficient catalytic electrodes. | Mengxia Li Tianxi Zheng Dongfei Lu Shiwei Dai Xin Chen Xinchen Pan Dibo Dong Rengui Weng Gang Xu Fanan Wang | 2023 | Journal of Energy Chemistry2023，，9： | 1 |
| 6 | Eosinophils promote pulmonary matrix destruction and emphvsema via Cathepsin L显示文摘Patients with chronic obstructive pulmonary disease(COPD)who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.This implies the potential involvement of eosinophils in the development of emphysema.However,the precise mechanisms underlying the development of eosinophil-mediated emphysema remain unclear.In this study,we employed single-cell RNA sequencing to identify eosinophil subgroups in mouse models of asthma and emphysema,followed by functional analyses of these subgroups.Assessment of accumulated eosinophils unveiled distinct transcriptomes in the lungs of mice with elastase-induced emphysema and ovalbumin-induced asthma.Depletion of eosinophils through the use of anti-interleukin-5 antibodies ameliorated elastase-induced emphysema.A particularly noteworthy discovery is that eosinophil-derived cathepsin L contributed to the degradation of the extracellular matrix,thereby leading to emphysema in pulmonary tissue Inhibition of cathepsin L resulted in a reduction of elastase-induced emphysema in a mouse model.Importantly,eosinophil levels correlated positively with serum cathepsin L levels,which were higher in emphysema patients than those without emphysema.Expression of cathepsin L in eosinophils demonstrated a direct association with lung emphysema in COPD patients.Collectively,these findings underscore the significant role of eosinophil-derived cathepsin L in extracellular matrix degradation and remodeling,and its relevance to emphysema in coPD patients.Consequently,targeting eosinophil-derived cathepsin L could potentially offer a therapeutic avenue for emphysema patients.Further investigations are warranted to explore therapeutic strategies targeting cathepsin L in emphysema patients. | Xia Xu Tao Yu Lingling Dong Rainer Glauben Siyuan Wu Ronghua Huang Shiwei Qumu Chenli Chang Jing Guo Lin Pan Ting Yang Xin Lin Ke Huang Zhihua Chen Chen Wang | 2023 | Signal Transduction and Targeted Therapy2023，8，11： | 1 |
| 7 | Kinetically accelerated and high-mass loaded lithium storage enabled by atomic iron embedded carbon nanofibers显示文摘Carbonaceous materials represent the dominant choice of materials for anodic lithium storage in many energy storage devices.Nevertheless,the nonpolar carbonaceous materials offer weak adsorption toward Li+that largely denies the high-rate Li+storage.Herein,the atomic Fe sites decorated carbon nanofibers(AICNFs)facilely produced by electrospinning are reported for kinetically accelerated Li+storage.Theoretical calculation reveals that the atomic Fe sites possess coordination unsaturated electronic configuration,enabling suitable bonding energy and facilitated diffusion path of Li+.As a result,the optimal structure displays a high capacitive contribution up to 95.9%at a scan rate of 2.0 mV·s^(−1).In addition,ultrahigh capacity retention of 97%is afforded after 5,000 cycles at a current density of 3 A·g^(−1).Moreover,the interlaced fiber structure enabled by electrospinning benefits structural stability and improved conductivity even at thick electrodes,thus allowing a high areal capacity of 1.76 mAh·cm−2 at a loading of 8 mg·cm−2.Because of these structure and performance merits,the lithium-ion capacitor containing the AICNF-based anode delivers a high energy density and large power density. | Qian Xu Yanan Li Chenghao Wu Xitong Sun Qiang Li Huabin Zhang Le Yu Yuanyuan Pan Yujuan Wang Shiwei Guo Mengdi Zhang Han Hu Mingbo Wu | 2022 | Nano Research2022，15，7： | 0 |
| 8 | Solid-state-reaction fabrication and properties of a high-doping Nd:YAG transparent laser ceramic显示文摘High-quality neodymium-doped yttrium aluminum garnet(Nd:YAG)transparent ceramic(4.0 mole percent)was fabricated by a solid-state reaction method and vacuum sintering.The microstructure,optical transmittance,spectral properties and laser performance were investigated.The average grain size of the sample is about 10 mm.The transmittance of a 2.8-mm thick sample reaches 79.5%at the laser wavelength of 1064 nm.The highest absorption peak is centered at 807 nm and the absorption coefficient is 13.9 cm^(-1).The absorption coefficient at the laser wavelength is 0.2 cm^(-1).The main emission peak is at 1064 nm and the fluorescence lifetime is 102 ms.A laser diode(808 nm)whose maximum output is about 1000 mW was used as a pump source and an endpumped laser experiment was performed.The 1064 nm-CW-laser output was obtained and the threshold is 733 mW.With 998 mW of maximum absorbed pump power,a laser output of 17 mW is obtained with a slope efficiency of 6.1%. | Jiang LI Yusong WU Yubai PAN Wenbin LIU Liqiong AN Shiwei WANG Jingkun GUO | 2008 | Frontiers of Chemical Science and Engineering2008，2，3： | 0 |
| 9 | An improved master-apprentice evolutionary algorithm for minimum independent dominating set problem显示文摘The minimum independent dominance set(MIDS)problem is an important version of the dominating set with some other applications.In this work,we present an improved master-apprentice evolutionary algorithm for solving the MIDS problem based on a path-breaking strategy called MAE-PB.The proposed MAE-PB algorithm combines a construction function for the initial solution generation and candidate solution restarting.It is a multiple neighborhood-based local search algorithm that improves the quality of the solution using a path-breaking strategy for solution recombination based on master and apprentice solutions and a perturbation strategy for disturbing the solution when the algorithm cannot improve the solution quality within a certain number of steps.We show the competitiveness of the MAE-PB algorithm by presenting the computational results on classical benchmarks from the literature and a suite of massive graphs from real-world applications.The results show that the MAE-PB algorithm achieves high performance.In particular,for the classical benchmarks,the MAE-PB algorithm obtains the best-known results for seven instances,whereas for several massive graphs,it improves the best-known results for 62 instances.We investigate the proposed key ingredients to determine their impact on the performance of the proposed algorithm. | Shiwei PAN Yiming MA Yiyuan WANG Zhiguo ZHOU Jinchao JI Minghao YIN Shuli HU | 2023 | Frontiers of Computer Science2023，17，4： | 0 |
| 10 | A Microsimulation of the Old-age Pension Policy显示文摘The old-age pension system is an important constituent part of the social security system in China, but in this respect revenue and expenditure are increasingly out of balance and the pressure in financial expenditure is increasing. At present, old-age pension institutional restructuring has become a hot topic in society and in academic circles, | Zhang Shiwei & Li Xue, the Research Center of Quantitative Economics, Jilin University Fan Lizhuang, the Statistics Bureau of Jilin Province Pan Jiabin | 2006 | Social Sciences in China2006，27，1： | 0 |
| 11 | Research Progress in Agricultural Vulnerability to Climate Change显示文摘与加深气候变化研究,更多的注意对对气候变化的弱点被给予了。与水资源,森林和另外的自然生态系统相比,农业对气候变化更脆弱,科学地从而估计农业危险到气候变化具有到合理、有效的改编策略的明确的表达的大意义。在这篇论文,作者从对气候变化,研究话题,和评估方法论的气候变化弱点和农业危险的定义的观点给研究的全面评论。包括情形申请,方法,和无常,在当前的研究的存在问题被分析,并且同时,为在对农业危险的评价的未来研究的方向的视觉也被介绍。引证道, S. ,徐·伊, K. 刘,等, 2011:在对气候变化的农业弱点研究进步。副词。Clim。变化物件, 2 (4 ) , doi:10.3724/SP.J.1248.2011.00203。 | Shengcai Tao Yinlong Xu Ke Liu Jie Pan Shiwei Gou | 2011 | Advances in Climate Change Research2011，2，4： | 0 |
| 12 | Current insights into the oncogenic roles of lncRNA LINC00355显示文摘Long noncoding RNAs(lncRNAs)are a class of nonprotein-coding transcripts that are longer than 200 nucleotides.LINC00355 is a lncRNA located on chromosome 13q21.31 and is consistently upregulated in various cancers.It regulates the expression of downstream genes at both transcriptional and posttranscriptional levels,including eight microRNAs(miR-15a-5p,miR-34b-5p,miR-424-5p,miR-1225,miR-217-5p,miR-6777-3p,miR-195,and miR-466)and three protein-coding genes(ITGA2,RAD18,and UBE3C).LINC00355 plays a role in regulating various biological processes such as cell cycle progression,proliferation,apoptosis,epithelial-mesenchymal transition,invasion,and metastasis of cancer cells.It is involved in the regulation of the Wnt/β-catenin signaling pathway and p53 signaling pathway.Upregulation of LINC00355 has been identified as a high-risk factor in cancer patients and its increased expression is associated with poorer overall survival,recurrence-free survival,and disease-free survival.LINC00355 upregulation has been linked to several unfavorable clinical characteristics,including advanced tumor node metastasis and World Health Organization stages,reduced Karnofsky Performance Scale scores,increased tumor size,greater depth of invasion,and more extensive lymph node metastasis.LINC00355 induces chemotherapy resistance in cancer cells by regulating five downstream genes,namely HMGA2,ABCB1,ITGA2,WNT10B,and CCNE1 genes.In summary,LINC00355 is a potential oncogene with great potential as a diagnostic marker and therapeutic target for cancer. | Jinze Shen Xinming Su Ming Pan Zehua Wang Yufei Ke Qurui Wang Jingyin Dong Shiwei Duan | 2023 | Cancer Innovation2023，2，6： | 0 |
| 13 | A ratiometric fluorescent probe for alkaline phosphatase with high sensitivity显示文摘Alkaline phosphatase(ALP)is one of essential biomarkers in mammalian tissue.Here we report a ratiometric probe for ALP,which is rationally designed and synthesized by employing ESIPT fluorophore N-(3-(benzo[d]thiazol-2-yl)-4-hydroxyphenyl)benzamide(BTHPB).The enzymatic dephosphorylation converts the probe to BTHPB,which exhibits a large spectral red-shift(120 nm),allowing extremely high sensitivity of ALP sensing at 0.004 mU/mL.The probe also shows excellent biocompatibility and has been applied for monitoring the endogenic ALP in living cells. | Yangyang Yang Chen Zhang Rizhao Pan Shiwei Zhang Shengtao Yao Yao Tang Weilong Zhu Liyue Wang Weiping Zhu Yufang Xu Xuhong Qian | 2020 | Chinese Chemical Letters2020，31，1： | 0 |
| 14 | How Does Digital Economy Promote Green Innovation?Empirical Evidencefrom Chinese Cities显示文摘This paper examines the impact of digital economy on the output of urban green innovation and its working mechanisms from the perspective of green technological innovation and on the basis of Chinese cities'panel data.The empirical study indicates that the digital economy effectively improves the output of urban green innovation in a way that is inclusive to medium and small cities and more effective in areas with a more market-oriented structure.Digital economy improves urban green innovation by promoting economic agglomeration and optimizing regional financial structure,to contribute to green technology's spillover effect and provide a favorable financial environment for green innovation.Further analysis has found that green innovation arising from the development of digital economy effectively reduces pollution and emission.The conclusions provide meso-level empirical evidence for a profound understanding of digital economy's impact on green innovation as well as theoretical guidance and policy recommendations for speeding up green transformation in the new context of development. | WEI Shiwei DU Jinmin PAN Shuang | 2022 | China Economic Transition2022，5，3： | 0 |
| 15 | The SlTPL3–SlWUS module regulates multi-locule formation in tomato by modulating auxin and gibberellin levels in the shoot apical meristem显示文摘Malformed fruits depreciate a plant’s market value.In tomato(Solanum lycopersicum),fruit malformation is associated with the multi-locule trait,which involves genes regulating shoot apical meristem(SAM)development.The expression pattern of TOPLESS3(SITPL3)throughout SAM development prompted us to investigate its functional significance via RNA interference(RNAi)and clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9(Cas9)-mediated gene editing.Lower SITPL3 transcript levels resulted in larger fruits with more locules and larger SAMs at the 5 d after germination(DAG5)stage.Differentially expressed genes in the SAM of wild-type(WT)and SITPL3-RNAi plants,identified by transcriptome deep sequencing(RNA-seq),were enriched in the gibberellin(GA)biosynthesis and plant hormone signaling pathways.Moreover,exogenous auxin and paclobutrazol treatments rescued the multi-locule phenotype,indicating that SITPL3 affects SAM size by mediating auxin and GA levels in the SAM.Furthermore,SITPL3 interacted with WUSCHEL(SIWUS),which plays an important role in SAM size maintenance.We conducted RNA-seq and DNA affinity purification followed by sequencing(DAP-seq)analyses to identify the genes regulated by SITPL3 and SIWUS in the SAM and to determine how they regulate SAM size.We detected24 overlapping genes regulated by SITPL3 and SIWUS and harboring an SIWUS-binding motif in their promoters.Furthermore,functional annotation revealed a notable enrichment for functions in auxin transport,auxin signal transduction,and GA biosynthesis.Dual-luciferase assays also revealed that SITPL3 enhances SIWUS-mediated regulation(repression and activation)of SIPIN3 and SIGA2 ox4 transcription,indicating that the SITPL3-SIWUS module regulates SAM size by mediating auxin distribution and GA levels,and perturbations of this module result in enlarged SAM.These results provide novel insights into the molecular mechanism of SAM maintenance and locule formation in tomato and highlight the SITPL3-SIWUS module as a key regulator. | Shiwei Song Binbin Huang Zanlin Pan Qiuxiang Zhong Yinghua Yang Da Chen Lisha Zhu Guojian Hu Mi He Caiyu Wu Mohammed Zouine Riyuan Chen Mondher Bouzayen Yanwei Hao | 2022 | Journal of Integrative Plant Biology2022，64，11： | 0 |
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