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13篇 您的检索式:作者名="Shuogui"
    题名 作者 年代 出处 被引量
1Calcium silicate bioactive ceramics induce osteogenesis through oncostatin M显示文摘Immune reactions are a key factor in determining the destiny of bone substitute materials after implantation.Macrophages,the most vital factor in the immune response affecting implants,are critical in bone formation,as well as bone biomaterial-mediated bone repair.Therefore,it is critical to design materials with osteoimmunomodulatory properties to reduce host-to-material inflammatory responses by inducing macrophage polarization.Our previous study showed that calcium silicate(CS)bioceramics could significantly promote osteogenesis.Herein,we further investigated the effects of CS on the behavior of macrophages and how macrophages regulated osteogenesis.Under CS extract stimulation,the macrophage phenotype was converted to the M2 extreme.Stimulation by a macrophage-conditioned medium that was pretreated by CS extracts resulted in a significant enhancement of osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs),indicating the important role of macrophage polarization in biomaterial-induced osteogenesis.Mechanistically,oncostatin M(OSM)in the macrophage-conditioned medium promoted osteogenic differentiation of BMSCs through the ERK1/2 and JAK3 pathways.This in vivo study further demonstrated that CS bioceramics could stimulate osteogenesis better thanβ-TCP implants by accelerating new bone formation at defective sites in the femur.These findings improve our understanding of immune modulation of CS bioactive ceramics and facilitate strategies to improve the in vitro osteogenesis capability of bone substitute materials.Panyu Zhou Demeng Xia Zhexin Ni Tianle Ou Yang Wang Hongyue Zhang Lixia Mao Kaili Lin Shuogui Xu Jiaqiang Liu 2021Bioactive Materials2021,6,3:5
2Modified posterior soft tissue repair for the prevention of early postoperative dislocation in total hip arthroplasty显示文摘Yuntong Zhang Yang Tang Chuncai Zhang Xue Zhao Yang Xie Shuogui Xu 2013International Orthopaedics2013,,6:2
3Application of a shape-memory alloy internal fixator for treatment of acetabular fractures with a follow-up of two to nine years in China显示文摘Xinwei Liu Shuogui Xu Chuancai Zhang 0,,:1
4Design and Clinical Application of Proximal Humerus显示文摘Xu Shuogui Zhang Chuncai 0,,:1
5Biomechanical study of posteriorwall acetabular fracture fixation using acetabular tridimensional memory alloyfixation system显示文摘Liu Xinwei Xu Shuogui Zhang chuncai 2010Clinical Biomechanics2010,25,:1
6Shape memory behaviour of radiation-crosslinked PCL/PMVS blends显示文摘Guangming Zhu Shuogui Xu Jinhua Wang 2006Radiation Physics and Chemistry2006,75,:1
7Knockdown of Burton’s tyrosine kinase confers potent protection against sepsis-induced acute lung injury显示文摘Panyu Zhou Bing Ma Shuogui Xu Shijie Zhang Hongtai Tang Shihui Zhu Shichu Xiao Daofeng Ben Zhaofan Xia 2014Cell Biochemistry and Biophysics2014,,2:1
8Design and clinical applications of swan-like memory-compressive connector for upper limb diaphysis显示文摘 Shuogui Xu Jialin Wang 2002Material Science Forum2002,394,:1
9Research and Development of Open CNC System Based on PC and Motion Controller显示文摘XU Xiaoming LI Yi Wang Shuogui 2012Procedia Engineering2012,,29:1
10Treatment of bone nonunion and bone defects associated with unsnccessful humeral condylar fracture repair with autogenous iliac bone reconstruction显示文摘Yunfei Niu Yushu Bai Shuogui Xu etal 2012J Shoulder Elbow Surg2012,21,:1
11Shape memory behaviour of radiation-crosslinked PCL/PMVS blends显示文摘Guangming Zhu Shuogui Xu Jinhua Wang 2006Radiation Physics and Chemistry2006,,75:1
12Research and Development of Open CNC System Based on PC and Motion Controller显示文摘Xu Xiaoming Li Yi Sun Jihong Wang Shuogui 2012Procedia Engineering2012,,29:1
13Design and clinical applications of swan like memory compressive connector for upper limb diaphysis 显示文摘Chuncai Zhang Shuogui Xu Jialin Wang 2002Material Science Forum2002,394,:1
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