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| 1 | Evaluation of a new qPCR test to identify the organisms causing high total bacterial count in bulk tank milk显示文摘Milk quality in bulk tank milk(BTM)is measured by flow cytometry technology as total bacterial count(TBC)and somatic cell count(SCC).To investigate SCC problems,culture or PCR can be used to identify mastitis causing bacteria,e.g.,Mastit 4,a commercially available qPCR test.TBC in BTM can be investigated further using culture-based methods such as standard plate count,laboratory pasteurization count,coliform count,and spore counts.To our knowledge,no qPCR addressing the bacteria involved in TBC has been commercially introduced.The aim of this study is to evaluate a recently introduced 3-h qPCR test,TBC 4.The TBC 4 qPCR detects four target groups,Pseudomonas,Streptococci,Enterobacteriacea/Enterococcus,and Bacillus/Clostridia.These target groups relate to problems on the farm such as cooling,mastitis,environment,and silage.We will continue with new research to compare the TBC 4 qPCR test with traditional culture.For this study,BTM samples from different TBC intervals were selected based on Bacto Count results found at routine payment investigation at Eurofins laboratory(Vejen,Denmark).These samples were analyzed using TBC 4 qPCR assay within 24 h.In total,346 BTM samples were divided into six different intervals of colony forming units(CFU).For all four targets in each of the different intervals of CFU,the percent of positive samples,the average C_t-value,the percent of positive samples with C_t<30 and C_t<25 were calculated.For Pseudomonas,Streptococci,and Enterobacteriacea/Enterococcus,the number of positive samples with lower C_t-values(high bacteria content)correlated with the CFU mL^(–1).We found Enterobacteriacea/Enterococcus,Pseudomonas,and Streptococci in high number of bacteria(C_t<25)in 25,19 and 56%of samples with CFU mL^(–1) between 50 001–100 000 and 53,44,and 39%in samples with CFU mL^(–1)>100 000.The TBC 4 qPCR test showed to be a strong and fast tool for farmers,advisors and service technicians to address problems with high TBC and ensuring the delivery of good quality milk to the dairy. | Jorgen Katholm Lene Trier Olesen Anders Petersen Snorri Sigurdsson | 2018 | Journal of Integrative Agriculture2018，17，6： | 3 |
| 2 | Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC显示文摘 | Diego F. Calvisi Sara Ladu Alexis Gorden Miriam Farina Elizabeth A. Conner Ju–Seog Lee Valentina M. Factor Snorri S. Thorgeirsson | 2006 | Gastroenterology2006，，4： | 3 |
| 3 | Safety of same-day endoscopic ultrasound and endoscopic retrograde cholangiopancreatography under conscious sedation显示文摘AIM: To assess the tolerability and safety of same-day tandem procedures, endoscopic ultrasound (EUS) followed by endoscopic retrograde cholangiopancreatography (ERCP) under conscious sedation. METHODS: A retrospective review was conducted at Loma Linda University Medical Center, a tertiary-care center. All 54 patients who underwent EUS followed by ERCP (group A) from 2004 to 2006 were included in the study. A second group of 56 patients who underwent EUS only (group B), and a third group of 53 patients who underwent ERCP only (group C) during the same time period were selected consecutively as control groups for comparison. RESULTS: Conscious sedation was used in 96% of patients in group A. Mean dosages of meperidine and midazolam used in group A were signifi cantly higher than in group B or C. Mean recovery time in group A was not statistically longer than in group B or C. Therewas no signifi cant difference in the incidence of sedation-related and procedural-related complications. CONCLUSION: Tandem EUS/ERCP procedure can be safely performed under conscious sedation with minimal adverse events. Combined procedures, however, are associated with higher dosages of sedatives, and slightly longer recovery time. | Kendrick Che Natasha Muckova Snorri Olafsson Wichit Srikureja | 2010 | World Journal of Gastroenterology2010，16，26： | 2 |
| 4 | Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes显示文摘 | Viktória László Katalin Dezs? Kornélia Baghy Veronika Papp Ilona Kovalszky Géza Sáfrány Snorri S. Thorgeirsson Peter Nagy Sándor Paku | 2008 | Histochemistry and Cell Biology2008，，5： | 2 |
| 5 | Slaughter quality and rigor contraction in farmed turbot (Scophthalmus maximus ); a comparison between different stunning methods显示文摘 | ROTH Bjorn IMSLAND Albert GUNNARSSON Snorri | 2007 | Aquaculture2007，10，： | 1 |
| 6 | The interaction of temperature and salinity on growth and food conversion in juvenile turbot Scophthalmus maximus 显示文摘 | ALBERT K I ATLE F SNORRI G | 2001 | Aquaculture2001，198，34： | 1 |
| 7 | Dramatic reduction of liver cancer incidence in young adults: 28 year follow-up of etiological interventions in an endemic area of China显示文摘 | Zongtang Sun Taoyang Chen Snorri S. Thorgeirsson Qimin Zhan Jianguo Chen Ju-Hyun Park Peixin Lu Chu Chieh Hsia Nengjin Wang Libin Xu Lingling Lu Fei Huang Yuanrong Zhu Jianhua Lu Zhengping Ni Qinan Zhang Yuying Wu Guoting Liu Zhiyuan Wu Chunfeng Qu Mitche | 2013 | Carcinogenesis2013，，8： | 1 |
| 8 | Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits显示文摘 | Jens U. Marquardt Daekwan Seo Jesper B. Andersen Matthew C. Gillen Myoung Soo Kim Elizabeth A. Conner Peter R. Galle Valentina M. Factor Young Nyun Park Snorri S. Thorgeirsson | 2014 | Journal of Hepatology2014，，2： | 1 |
| 9 | Dominant role of hepatitis B Virus and cofactor role of aflatoxin in hepato-carcinogenesis in Qidong,China显示文摘 | LIHUA M SNORRI S THORGEIRSSON | 2002 | Hepatotology2002，36，5： | 1 |
| 10 | β-Cell-Specific Ablation of the Hepatocyte Growth Factor Receptor Results in Reduced Islet Size, Impaired Insulin Secretion, and Glucose Intolerance显示文摘 | Chunsun Dai Chang-Goo Huh Snorri S. Thorgeirsson Youhua Liu | 2005 | The American Journal of Pathology2005，，2： | 1 |
| 11 | DLC‐1:a Rho GTPase‐activating protein and tumour suppressor显示文摘 | Marian E.Durkin Bao‐ZhuYuan XiaolingZhou Drazen B.Zimonjic Douglas R.Lowy Snorri S.Thorgeirsson Nicholas C.Popescu | 2007 | Journal of Cellular and Molecular Medicine2007，，5： | 1 |
| 12 | DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development显示文摘 | Marian E. Durkin Miriam R. Avner Chang-Goo Huh Bao-Zhu Yuan Snorri S. Thorgeirsson Nicholas C. Popescu | 2005 | FEBS Letters2005，，5： | 1 |
| 13 | Gill Na+ , K+ -ATPase activity, plasma chloride and osmolality in juvenile turbot ( Scophthalmus maximus) reared at different temperatures and salinities 显示文摘 | ALBERT K I SNORRI G ATLE F | 2003 | Aquaculture2003，218，14： | 1 |
| 14 | Factors explaining variance in perceived pain in women with fibromyalgia显示文摘 | Eva AM Snorri O Anders L | 2002 | BMC Musculoskeletal Disorders2002，3，1： | 1 |
| 15 | The interaction of temperature and salinity on growth and food conversion in juvenile turbot显示文摘 | Albert K I Atle F Snorri G | 2001 | Aquaculture2001，198，： | 1 |
| 16 | Loss of c-Met accelerates development of liver fibrosis in response to CCl 4 exposure through deregulation of multiple molecular pathways显示文摘 | Jens U. Marquardt Daekwan Seo Luis E. Gómez-Quiroz Koichi Uchida Matthew C. Gillen Mitsuteru Kitade Pal Kaposi-Novak Elizabeth A. Conner Valentina M. Factor Snorri S. Thorgeirsson | 2012 | BBA - Molecular Basis of Disease2012，，6： | 1 |
| 17 | Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease 显示文摘 | John JK John SL Snorri O | 2014 | Helicobacter2014，19，2： | 1 |
| 18 | Dominant role of hepatitis B Virus and cofactor role of aflatoxin in hepato-carcinogenesis in Qidong, China 显示文摘 | LIHUA M SNORRI S THORGEIRSSON | 2002 | Hepatotology2002，36，5： | 1 |
| 19 | Sixty‐five gene‐based risk score classifier predicts overall survival in hepatocellular carcinoma显示文摘 | Soo Mi Kim Sun‐Hee Leem In‐Sun Chu Yun‐Yong Park Sang Cheol Kim Sang‐Bae Kim Eun Sung Park Jae Yun Lim Jeonghoon Heo Yoon Jun Kim Dae‐Ghon Kim Ahmed Kaseb Young Nyun Park Xin Wei Wang Snorri S. Thorgeirsson Ju‐Seog Lee | 2012 | Hepatology2012，，5： | 1 |
| 20 | Activation of the canonical Wnt/β-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer显示文摘 | Diego F. Calvisi Elizabeth A. Conner Sara Ladu Eric R. Lemmer Valentina M. Factor Snorri S. Thorgeirsson | 2005 | Journal of Hepatology2005，，6： | 1 |
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